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[World Report] RFK Jr vaccine statement overturns decision-making conventions
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01180-8/fulltext?rss=yes
Published: June 7, 2025 00:00
US Health Secretary Kennedy's withdrawal of COVID-19 vaccine recommendation for pregnant women and children surprised officials and bypassed key committees. Tony Kirby reports.
[Correspondence] Gaza deaths and lawful warfare – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00872-4/fulltext?rss=yes
Published: June 7, 2025 00:00
We acknowledge the Correspondence by Joel Zivot and colleagues regarding our Article.1
[World Report] Health aid funding falls short as Gaza crisis deepens
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01181-X/fulltext?rss=yes
Published: June 7, 2025 00:00
Despite strong advocacy, donor funding for humanitarian relief and health in the occupied Palestinian territories remains critically low. John Zarocostas reports.
[Correspondence] US disinvestment threatens progress on violence prevention
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00909-2/fulltext?rss=yes
Published: June 7, 2025 00:00
Amid widespread concern about the global consequences of recent US funding cuts, violence prevention and response remain under-discussed.1 Nearly one in three women worldwide—approximately 736 million—have been victim to physical or sexual violence from an…
[Editorial] From innovation to impact in cardiovascular disease
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01182-1/fulltext?rss=yes
Published: June 7, 2025 00:00
Cardiovascular disease remains the world's leading cause of death and a major source of disability. Global deaths due to cardiovascular disease increased from 12·4 million in 1990 to 19·8 million in 2022, reflecting not only population growth and ageing…
[Comment] CAR T-cell therapy in advanced gastro-oesophageal cancer
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01095-5/fulltext?rss=yes
Published: June 7, 2025 00:00
Chimeric antigen receptor (CAR) T-cell therapy has shown remarkable clinical efficacy in haematological malignancies, currently representing a well established second-line treatment option for patients with relapsed or refractory B-cell lymphomas, B-cell…
[Correspondence] Gaza deaths and lawful warfare
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00873-6/fulltext?rss=yes
Published: June 7, 2025 00:00
International agreements govern the legality of going to war. Once conflict commences, the conduct of war should conform to International Humanitarian Law1 and the four Geneva Conventions,2 both of which foresee civilian deaths due to military necessity.…
[World Report] Papua New Guinea's Village Health Attendants
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01184-5/fulltext?rss=yes
Published: June 7, 2025 00:00
Papua New Guinea's community volunteers provide essential services and health promotion, but the absence of financial support makes life difficult for many. Sima Barmania reports.
[Correspondence] The relevance of WHO behavioural health insights
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00835-9/fulltext?rss=yes
Published: June 7, 2025 00:00
The cuts in WHO funding caused by the international situation and US withdrawal are of great concern. As behavioural scientists and public health professionals, we would like to highlight how WHO Europe's Behavioural and Cultural Insights (BCI) unit has…
[Correspondence] Being a victim of a predatory journal
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00821-9/fulltext?rss=yes
Published: June 7, 2025 00:00
I read with deep respect and reflection Christine Laine and colleagues’ recent publication on predatory journals.1 I have been working in rural Maharashtra, India since 1976, conducting clinical research on various rural health issues. Over the years, I…
[Articles] Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00860-8/fulltext?rss=yes
Published: May 31, 2025 20:00
This is the first randomised controlled trial of CAR T-cell therapy in solid tumours globally. Satri-cel treatment resulted in a significant improvement in progression-free survival, with a manageable safety profile. These results support satri-cel as a…
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01102-X/fulltext?rss=yes
Published: May 31, 2025 00:00
Lenze EJ, Mulsant BH, Blumberger DM, et al. Efficacy, safety, and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in late life: a randomised, double-blind, placebo-controlled trial. Lancet 2015; 386:…
[Correspondence] Global trends and projections in antimicrobial resistance
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00810-4/fulltext?rss=yes
Published: May 31, 2025 00:00
The systematic analysis by the GBD 2021 Antimicrobial Resistance Collaborators addresses an important gap in the literature by presenting detailed estimates of antimicrobial resistance (AMR) burden across 204 countries and territories and leverages…
[World Report] Janabi elected as new WHO Regional Director for Africa
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01141-9/fulltext?rss=yes
Published: May 31, 2025 00:00
Promising a vision of universal health coverage and resilient health systems, a Tanzanian cardiologist is set to become one of Africa's most influential health leaders. Paul Adepoju reports.
[Correspondence] Global trends and projections in antimicrobial resistance
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00806-2/fulltext?rss=yes
Published: May 31, 2025 00:00
The systematic analysis of the global burden of bacterial antimicrobial resistance (AMR) 1990–2021 by the GBD 2021 Antimicrobial Resistance Collaborators1 will help to improve understanding of global trends of AMR, but the authors’ interpretations of the…
[Comment] Safety of low-intensity monitoring after thrombolysis in acute ischaemic stroke
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01097-9/fulltext?rss=yes
Published: May 31, 2025 00:00
30 years have passed since the landmark publication of the National Institute of Neurological Disorders and Stroke (NINDS) trial of tissue plasminogen activator for acute ischaemic stroke. The NINDS trial assessed neurological and functional improvements…
[Correspondence] Critical factors for improving maternal health
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00726-3/fulltext?rss=yes
Published: May 31, 2025 00:00
The timely Editorial1 on prioritising and investing in maternal health captures the scale of the challenges facing UK maternity services. However, there are important gaps in the analysis and the wider discourse. Focusing on failures in specific hospitals…
[Correspondence] Global trends and projections in antimicrobial resistance
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00809-8/fulltext?rss=yes
Published: May 31, 2025 00:00
The GBD 2021 Antimicrobial Resistance Collaborators raised alarming concerns about worsening bacterial antimicrobial resistance (AMR), which they projected will kill 39 million people by 2050.1 However, we would like to offer a different perspective…
[Correspondence] Implementation challenges of personalised phage therapy
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00737-8/fulltext?rss=yes
Published: May 31, 2025 00:00
Bacteriophage therapy, first applied in 1919 to be forgotten after the large-scale introduction of antibiotics in the 1940s, was rediscovered in the midst of the global antimicrobial resistance crisis. However, the high specificity of bacteriophages…
[Correspondence] Prioritising maternal health must include care before pregnancy
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00725-1/fulltext?rss=yes
Published: May 31, 2025 00:00
The number of women dying during or soon after pregnancy in the UK is higher today than 10 years ago,1 with shocking reports of avoidable deaths, as articulated by The Lancet.2
[World Report] The medicine of…Hajj
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01143-2/fulltext?rss=yes
Published: May 31, 2025 00:00
In our continuing series on medicine in unique circumstances, Talha Burki looks at how medical care is provided for the 2 million Muslims expected to perform Hajj in Mecca this year.
[Correspondence] Global trends and projections in antimicrobial resistance
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00808-6/fulltext?rss=yes
Published: May 31, 2025 00:00
We have read the systematic analysis by the GBD 2021 Antimicrobial Resistance Collaborators1 with great interest. Although we commend this work, we would like to highlight a few issues of concern.
[World Report] WHA adopts new strategy on traditional medicine
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01142-0/fulltext?rss=yes
Published: May 31, 2025 00:00
WHO is seeking ways to integrate traditional medicine—relied on by billions worldwide—into wider health systems. Talha Burki reports.
[Correspondence] Moving from evidence to prioritised action on AMR
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00738-X/fulltext?rss=yes
Published: May 31, 2025 00:00
Reductions in global health funding heighten the need for improved prioritisation of the remaining funds. Antimicrobial resistance (AMR) is an agreed priority, predicted to account for 1·91 million attributable deaths annually in humans by 2050.1 Ambitious…
[Correspondence] Global trends and projections in antimicrobial resistance – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00811-6/fulltext?rss=yes
Published: May 31, 2025 00:00
We thank Manica Balasegaram, Edmond Siu-Keung Ma and colleagues, Abebaw Fekadu and colleagues, Sylvia Yang Liu and colleagues, and Vimalraj Selvaraj and colleagues for their insightful contributions to this important topic. To our knowledge, our systematic…
[Correspondence] Global trends and projections in antimicrobial resistance
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00807-4/fulltext?rss=yes
Published: May 31, 2025 00:00
The GBD 2021 Antimicrobial Resistance Collaborators estimated the deaths associated with and attributable to bacterial antimicrobial resistance (AMR) from 1990 to 2021, and produced forecasts of AMR burden up to 2050 using robust methods.1 We provide…