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The Lancet RSS feed.
Site URL: www.thelancet.com/journals/lancet/issue/current
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Posts: 54
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[Correspondence] Endometriosis: an Australian perspective on encouraging change
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02511-X/fulltext?rss=yes
Published: February 1, 2025 00:00
I was interested to read the Editorial from Oct 5, 2024,1 which mentioned the National Action Plan for Endometriosis (NAPE). As an Australian emergency physician, I wanted to offer a lived patient experience.
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00159-X/fulltext?rss=yes
Published: February 1, 2025 00:00
Naci H, Murphy P, Woods B, Lomas J, Wei J, Papanicolas I. Population-health impact of new drugs recommended by the National Institute for Health and Care Excellence in England during 2000–20: a retrospective analysis. Lancet 2025; 405: 50–60—The copyright…
[Articles] Suspected and confirmed mpox cases in DR Congo: a retrospective analysis of national epidemiological and laboratory surveillance data, 2010–23
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02669-2/fulltext?rss=yes
Published: February 1, 2025 00:00
The incidence and geographical distribution of suspected mpox cases have increased substantially since 2010. Improvements in surveillance and decentralised testing are essential to monitor mpox trends and direct interventions effectively, to address the…
[World Report] Should alcohol carry cancer warning labels?
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00187-4/fulltext?rss=yes
Published: February 1, 2025 00:00
Associations between alcohol consumption and cancer are scientifically well established, but the public are often unaware of the links. Sharmila Devi reports.
[Correspondence] Sunitinib for the treatment of phaeochromocytomas and paragangliomas
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02782-X/fulltext?rss=yes
Published: February 1, 2025 00:00
The completion of the First International Randomized study in Malignant Progressive Pheochromocytoma and Paragangliomas (FIRSTMAPPP)1 trial by Eric Baudin and colleagues is indeed a success. However, the adverse events of sunitinib are substantial in…
[Comment] Rethinking surveillance after breast cancer
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00093-5/fulltext?rss=yes
Published: February 1, 2025 00:00
To provide best care for women with a personal history of breast cancer, follow-up after treatment completion is necessary. Annual surveillance mammography is an imperative part of this follow-up. Mammography is not a particularly good imaging test in this…
[Correspondence] Case for a health equity framework in health technology assessment
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02430-9/fulltext?rss=yes
Published: February 1, 2025 00:00
Improving health equity is essential for both individual wellbeing and societal prosperity. However, health opportunities are not equally distributed, with life expectancy varying substantially across different areas in England with a 20-year gap for women…
[World Report] Psychedelics for health
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00188-6/fulltext?rss=yes
Published: February 1, 2025 00:00
A wave of studies and recent regulatory approvals have renewed interest in the health applications of psychedelics. Talha Burki reports.
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00160-6/fulltext?rss=yes
Published: February 1, 2025 00:00
The Lancet. Infectious diseases in 2025: a year for courage and conviction. Lancet 2025; 405: 97—The International Day of Epidemic Preparedness was on Dec 27. This change has been made to the online version as of Jan 30, 2025.
[Articles] Annual versus less frequent mammographic surveillance in people with breast cancer aged 50 years and older in the UK (Mammo-50): a multicentre, randomised, phase 3, non-inferiority trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02715-6/fulltext?rss=yes
Published: February 1, 2025 00:00
For patients aged 50 years or older and at 3 years post diagnosis, less frequent mammograms were non-inferior compared with annual mammograms for breast cancer-specific survival, recurrence-free interval, and overall survival, and should be considered for…
[Perspectives] A doctor's lineage
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00157-6/fulltext?rss=yes
Published: February 1, 2025 00:00
As you lay dying in hospice, my father was sick in a hospital. Your prognosis was absolute. My father's diagnosis was elusive, his outcome uncertain. You both spoke to each other daily. Facetime, telephone lines. The weight of an ending hovering between…
[Perspectives] Preparing for the next pandemic
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00156-4/fulltext?rss=yes
Published: February 1, 2025 00:00
In a clinic in Guinea, a community health worker is puzzled by the number of people in a village becoming severely ill and reports this to their superior, who notifies the Ministry of Health about the outbreak. Across the world in San Francisco, USA, a…
[Correspondence] Future-proofing Europe and Central Asia: a renewed focus on child and adolescent health
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02507-8/fulltext?rss=yes
Published: February 1, 2025 00:00
The data are clear: Europe and Central Asia are failing their children. Hard-earned reductions in child mortality in the region are reversing or stagnating. Mental health concerns have doubled since the COVID-19 pandemic, with one in four children younger…
[Correspondence] Hughes Stovin syndrome is not associated with pulmonary embolism – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00154-0/fulltext?rss=yes
Published: February 1, 2025 00:00
We would like to thank Nikolas Ruffer and Martin Krusche for their considered Correspondence; their letter raised an important point regarding the nomenclature used in our case report. The authors correctly emphasise that the filling defects present on our…
[Perspectives] Chloe Orkin: forefronting social justice in medicine
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00155-2/fulltext?rss=yes
Published: February 1, 2025 00:00
HIV researcher and physician Chloe Orkin, Professor of Infection and Inequities at Queen Mary University of London, UK, embarked on her career at the age of just 16 years when she began her medical degree at the University of the Witwatersrand, South…
[Comment] Rising mpox trends in DR Congo: the neglected spread of an epidemic
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00137-0/fulltext?rss=yes
Published: February 1, 2025 00:00
The monkeypox virus is causing concurrent outbreaks of mpox in Africa, with more and more frequent exportations outside the continent.1 Although community transmission has established itself in a number of African countries, DR Congo undoubtedly bears the…
[Comment] Offline: The journey towards equality
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00192-8/fulltext?rss=yes
Published: February 1, 2025 00:00
Our world needs some good news. The French economist, Thomas Piketty, in his short book, Nature, Culture, and Inequality (2024), provides at least a glimmer of hope in otherwise overwhelming times: our world is getting progressively more equal. These…
[Correspondence] Sunitinib for the treatment of phaeochromocytomas and paragangliomas
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02781-8/fulltext?rss=yes
Published: February 1, 2025 00:00
The phase 2, randomised, non-comparative First International Randomized study in Malignant Progressive Pheochromocytoma and Paragangliomas (FIRSTMAPPP) by Eric Baudin and colleagues1 investigated sunitinib versus placebo in patients with metastatic…
[Correspondence] Nepal set to launch historic HPV vaccination programme
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00008-X/fulltext?rss=yes
Published: February 1, 2025 00:00
Nepal is set to launch its human papillomavirus (HPV) vaccination campaign on Feb 4, 2025, on World Cancer Day. Supported by Gavi, the Vaccine Alliance, WHO, and UNICEF, the campaign aims to immunise more than 1·6 million adolescent schoolgirls (grades 6…
[Editorial] Cancer registries: the bedrock of global cancer care
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00189-8/fulltext?rss=yes
Published: February 1, 2025 00:00
The International Agency for Research on Cancer predicts more than 35 million new cancer cases in 2050, a 77% increase from 2022. The greatest burden will fall on low-income and middle-income countries, where cancer mortality rates are expected to almost…
[Obituary] Maurice Henry King
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00158-8/fulltext?rss=yes
Published: February 1, 2025 00:00
Doctor, lecturer, and author. Born in Hatton, Sri Lanka, on Feb 7, 1927, he died on Aug 18, 2024, in Leeds, UK, aged 97 years.
[Correspondence] Sunitinib for the treatment of phaeochromocytomas and paragangliomas – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02783-1/fulltext?rss=yes
Published: February 1, 2025 00:00
We thank Alexander Sherry and colleagues and Sheng Zhang and colleagues for their interest in the First International Randomized study in Malignant Progressive Pheochromocytoma and Paragangliomas (FIRSTMAPPP) phase 2 trial methodology.
[Correspondence] Hughes Stovin syndrome is not associated with pulmonary embolism
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02558-3/fulltext?rss=yes
Published: February 1, 2025 00:00
We read with great interest the Clinical Picture by Cook and colleagues.1 The authors describe a man aged 76 years who developed recurrent venous thrombosis despite anticoagulation and progressive bilateral pulmonary artery aneurysms.
[Correspondence] Eliminating cervical cancer in the Tibetan Plateau
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02635-7/fulltext?rss=yes
Published: February 1, 2025 00:00
In 2020, WHO proposed the global strategy to accelerate the elimination of cervical cancer as a public health problem,1 which means 194 countries and regions have the responsibility to take action to ensure no one is neglected and left behind. 4 years have…
[Comment] Dual checkpoint blockade for microsatellite instability-high colorectal cancer
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00144-8/fulltext?rss=yes
Published: January 25, 2025 21:52
Metastatic colorectal cancer with microsatellite instability-high or mismatch repair-deficient status represents a distinct tumour subtype that accounts for around 5% of total colorectal cancer cases. Although standard chemotherapy has some efficacy in…
[Articles] Nivolumab plus ipilimumab versus nivolumab in microsatellite instability-high metastatic colorectal cancer (CheckMate 8HW): a randomised, open-label, phase 3 trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02848-4/fulltext?rss=yes
Published: January 25, 2025 21:52
Nivolumab plus ipilimumab showed superior progression-free survival versus nivolumab across all treatment lines, with a manageable safety profile, in patients with microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer.…
[Correspondence] A regional approach to addressing global health inequities
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02638-2/fulltext?rss=yes
Published: January 25, 2025 00:00
Adam Strobeyko and colleagues1 propose strengthening WHO's capacity to address pandemic product inequities through amendments to the International Health Regulations and establishing the Global Supply Chain and Logistics Network as a successor to the…
[Correspondence] The R21/Matrix-M malaria vaccine: questions remain – Author's reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02780-6/fulltext?rss=yes
Published: January 25, 2025 00:00
We thank the authors for their interest in our paper, and their queries. In response to Yue Li and Guangsen Liu, given the current situation of malaria deaths and cases increasing in recent years,1 it is imperative that an efficacious vaccine is deployed…
[Correspondence] Undervaccination and severe COVID-19 outcomes – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02866-6/fulltext?rss=yes
Published: January 25, 2025 00:00
We thank our colleagues for their interest in our Article.1 In response to Ari R Joffe, we provided estimates of the number of severe outcomes associated with a fully vaccinated counterfactual. These estimates controlled for time since the last positive…
[Comment] Durability of patient benefit from CT-guided chest pain management
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00100-X/fulltext?rss=yes
Published: January 25, 2025 00:00
Contemporary guidelines for the evaluation of patients with stable chest pain recommend coronary CT angiography (CCTA) as the preferred first-line test in most patients who do not have previously established coronary artery disease.1,2 These…
[Correspondence] The R21/Matrix-M malaria vaccine: questions remain
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02778-8/fulltext?rss=yes
Published: January 25, 2025 00:00
The R21/Matrix-M malaria vaccine offers the highest efficacy in the history of malaria vaccine development as reported by Mehreen Datoo and colleagues.1 The potential for saving the lives of African children must be harnessed immediately but cautiously,…
[Articles] Stopping of adalimumab in juvenile idiopathic arthritis-associated uveitis (ADJUST): a multicentre, double-masked, randomised controlled trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02468-1/fulltext?rss=yes
Published: January 25, 2025 00:00
Discontinuing adalimumab led to higher rates of recurrence of uveitis, arthritis, or both in patients with previously controlled juvenile idiopathic arthritis-associated uveitis. However, all patients who had treatment failure successfully regained control…
[Perspectives] Health advocacy in the history of US immigrants’ rights
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00103-5/fulltext?rss=yes
Published: January 25, 2025 00:00
Foreign-born practitioners in the health professions are critical to the health-care labour force in many high-income countries. In addition, both immigrant and non-immigrant health professionals have a stake in protecting the rights of their patients and…
[Correspondence] Leadership roles in response to mpox and Marburg virus disease outbreaks
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00009-1/fulltext?rss=yes
Published: January 25, 2025 00:00
Public health emergencies demand decisive leadership, proactive capacities, and swift, coordinated responses to mitigate their impacts on lives, livelihoods, and economies, particularly in Africa, where health systems have little resilience to public…
[Articles] Impact of SARS-CoV-2 spike antibody positivity on infection and hospitalisation rates in immunosuppressed populations during the omicron period: the MELODY study
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02560-1/fulltext?rss=yes
Published: January 25, 2025 00:00
All people with immunosuppression require ongoing access to COVID-19 protection strategies. Assessment of anti-S Ab responses, which can be performed at scale, can identify people with immunosuppression who remain most at risk, providing a mechanism to…
[Correspondence] Malaria and undernutrition in Angola
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00011-X/fulltext?rss=yes
Published: January 25, 2025 00:00
The 2024 WHO disease outbreak news report1 on malaria underscores the challenges posed in DR Congo and neighbouring regions.2 The update identifies acute respiratory infections complicated by malaria, with 891 infections and 48 deaths reported in children…
[Perspectives] Taking the temperature of humankind
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00102-3/fulltext?rss=yes
Published: January 25, 2025 00:00
In 2015 this journal published a report by the Lancet Commission on Health and Climate Change, making the case that the climate crisis could have catastrophic effects on human health. Abnormally high temperatures, extreme weather events, degradation of and…
[World Report] Trump's anticipated UNFPA defunding will harm millions
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00134-5/fulltext?rss=yes
Published: January 25, 2025 00:00
Women and girls will lose access to essential health services should the incoming US President cut funding. By Udani Samarasekera.
[Perspectives] Catherine Draper: nurturing early childhood development
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00101-1/fulltext?rss=yes
Published: January 25, 2025 00:00
When I spoke to researcher Catherine Draper, she was about to travel to work in a rural area of South Africa. Draper is Associate Professor in the MRC/Wits Developmental Pathways for Health Research Unit at the University of the Witwatersrand, South…
[Comment] Antibody testing to predict SARS-CoV-2 risk in immunocompromised people
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00098-4/fulltext?rss=yes
Published: January 25, 2025 00:00
The development of adaptive immunity to SARS-CoV-2 (in the shape of antibody, B, and T cells) is associated with protection against infection and severe disease, regardless of whether this is induced by infection, vaccination, or a combination of both.1 It…
[Comment] Uveitis in juvenile idiopathic arthritis: when to stop adalimumab?
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02616-3/fulltext?rss=yes
Published: January 25, 2025 00:00
Juvenile idiopathic arthritis is the most common chronic systemic disease associated with uveitis in childhood. Uveitis occurs in 11–22% of children with juvenile idiopathic arthritis.1 Due to the chronic course of intraocular inflammation, there is a high…
[Correspondence] The R21/Matrix-M malaria vaccine: questions remain
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02779-X/fulltext?rss=yes
Published: January 25, 2025 00:00
Several studies have found non-live vaccines, including the RTS,S malaria vaccine, to be associated with increased female mortality.1 It is therefore unfortunate that the recent paper by Mehreen Datoo and colleagues2 on the phase 3 trial of the new R21…
[Editorial] Wildfires: what does the evidence say?
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00136-9/fulltext?rss=yes
Published: January 25, 2025 00:00
The Californian wildfires have captured global attention. The Golden State is once again engulfed in flames, with neighbourhoods decimated and more than 40 000 acres of land reduced to ash and rubble. Lives have been lost, people are missing, communities…
[Correspondence] The R21/Matrix-M malaria vaccine: questions remain
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02777-6/fulltext?rss=yes
Published: January 25, 2025 00:00
I am writing to voice concerns over the findings of the phase 3 trial of the R21/Matrix-M malaria vaccine by Mehreen Datoo and colleagues.1 The study indicates that the vaccine's efficacy appears to decline over time, from an initial 79% in months 1–3 to…
[World Report] Repression of health-care workers continues in Belarus
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00135-7/fulltext?rss=yes
Published: January 25, 2025 00:00
As elections approach, doctors have described increasingly draconian crackdowns that are driving many to emigrate. Ed Holt reports.
[Comment] Offline: Making obesity matter
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00132-1/fulltext?rss=yes
Published: January 25, 2025 00:00
“None of us were entirely right, none of us were entirely wrong.” That was Francesco Rubino's wry comment on his Commission, published by The Lancet Diabetes and Endocrinology on Jan 14, 2025, and launched at the Royal College of Physicians in London. The…
[Correspondence] Polio in Sudan and other conflict zones: a call for urgent support
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02793-4/fulltext?rss=yes
Published: January 25, 2025 00:00
Polio is a highly viral infectious disease that poses a life-threating risk to young children, often leading to paralysis and death, and children who are not fully immunised are especially vulnerable. Since the initiation of the Global Polio Eradication…
[Articles] Coronary CT angiography-guided management of patients with stable chest pain: 10-year outcomes from the SCOT-HEART randomised controlled trial in Scotland
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02679-5/fulltext?rss=yes
Published: January 25, 2025 00:00
After 10 years, CCTA-guided management of patients with stable chest pain was associated with a sustained reduction in coronary heart disease death or non-fatal myocardial infarction. Identification of coronary atherosclerosis by CCTA improves long-term…
[World Report] WHO South-East Asia Regional Director faces investigation
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00133-3/fulltext?rss=yes
Published: January 25, 2025 00:00
Bangladesh's Anti-Corruption Commission has accused Saima Wazed of securing her position thanks to her mother, Bangladesh's former Prime Minister. Samaan Lateef reports.
[Correspondence] Undervaccination and severe COVID-19 outcomes
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02865-4/fulltext?rss=yes
Published: January 25, 2025 00:00
In their Article, the HDR UK COALESCE Consortium concluded that those who are fully vaccinated against SARS-CoV-2 are less likely to be admitted to hospital and to die with COVID-19.1 If the tests for SARS-CoV-2 infection are accurate and unbiased, this is…
[Corrections] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00105-9/fulltext?rss=yes
Published: January 25, 2025 00:00
GBD 2021 US Burden of Disease Collaborators. The burden of diseases, injuries, and risk factors by state in the USA, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet 2024; 404: 2314–40—In this Article, the x-axis labels…
[Correspondence] Undervaccination and severe COVID-19 outcomes
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02864-2/fulltext?rss=yes
Published: January 25, 2025 00:00
The HDR UK COALESCE Consortium concluded that “higher vaccination coverage would have been associated with considerable reduction in severe COVID-19 outcomes”.1 This statement requires some perspective.
[Correspondence] Global South leaders should strengthen strategic capacity
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02637-0/fulltext?rss=yes
Published: January 25, 2025 00:00
Madhukar Pai and colleagues1 highlight the need for Global North institutions to assume an allyship position in the decolonisation of global health. Pai and colleagues’ vision, anchored in principles of equity and justice, presents an ideal of what global…
[Obituary] Luciano Gattinoni
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00104-7/fulltext?rss=yes
Published: January 25, 2025 00:00
Influential specialist in intensive care medicine. Born on Jan 12, 1945, in Milan, Italy, he died on Dec 2, 2024, in Göttingen, Germany, aged 79 years.