🦜 The Lancet
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[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02716-8/fulltext?rss=yes
Published: December 21, 2024 00:00
Morris MJ, Castellano D, Herrmann K, et al. 177Lu-PSMA-617 versus a change of androgen receptor pathway inhibitor therapy for taxane-naive patients with progressive metastatic castration-resistant prostate cancer (PSMAfore): a phase 3, randomised,…
[Correspondence] From bad to worse: the unbreathable air of Lahore
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02601-1/fulltext?rss=yes
Published: December 21, 2024 00:00
Imagine stepping outside and each breath feels like a hazard—this situation is the grim reality for millions living in Lahore, Pakistan. The average air quality index (AQI) in Lahore from Oct 17 to Nov 16, 2024, ranged from unhealthy to hazardous (AQI 180…
[Correspondence] Xenotransplantation: the future is closer than we think
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02433-4/fulltext?rss=yes
Published: December 21, 2024 00:00
We read with interest the Offline piece on xenotransplantation published in The Lancet.1 As a research group that has made substantial preclinical contributions to the field of genetically modified pig-to-baboon liver xenotransplantation,2 we find the…
[Correspondence] HIV and alcohol misuse among miners in Zimbabwe
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02543-1/fulltext?rss=yes
Published: December 21, 2024 00:00
Zimbabwe has successfully reached the UNAIDS 95-95-95 HIV testing, treatment, and viral suppression targets; however, gaps remain particularly among the growing population of artisanal and small-scale miners, who are highly vulnerable to HIV. Sex work,…
[Correspondence] Concerns about the role of physician associates in UK clinical practice
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02607-2/fulltext?rss=yes
Published: December 21, 2024 00:00
In the Comment by Jessamy Bagenal on the roles of physician associates and doctors in the UK, professional protectionism is cited as a factor in opposing the appointment of physician associates.1 However, there are legitimate concerns2 that physician…
[Correspondence] The role of physican associates under Labour reforms
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02609-6/fulltext?rss=yes
Published: December 21, 2024 00:00
We found the Comment by Jessamy Bagenal to be an insightful exploration of the role of physician associates in the UK health-care system.1 Since its publication, the UK's political landscape has shifted with the election of the Labour Government, bringing…
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02752-1/fulltext?rss=yes
Published: December 21, 2024 00:00
Jairath V, Acosta Felquer ML, Jaihyun Cho R. IL-23 inhibition for chronic inflammatory disease. Lancet 2024; 404: 1679–92—In this Therapeutics paper, the name IL-23A in the abstract should have been IL-23. Also, the model of TYK2 activation shown in the…
[Correspondence] Physician associates and patient safety
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02608-4/fulltext?rss=yes
Published: December 21, 2024 00:00
We read Jessamy Bagenal's Comment about physician associates with concern and offer a crucial perspective prioritising patient safety and transparency.1 Research by the Royal College of General Practitioners found that 81% of respondents considered…
[Editorial] European health security needs a reboot in 2025
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02789-2/fulltext?rss=yes
Published: December 21, 2024 00:00
2025 marks the centenary of the Locarno Treaties—a series of treaties between European countries after World War 1, negotiated in October, 1925, in Locarno, Switzerland, and signed in London in December, 1925. These agreements ushered in a period of…
[Correspondence] Combined liver–kidney transplantation: 40 years of saving lives
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02320-1/fulltext?rss=yes
Published: December 21, 2024 00:00
Since the first successful combined liver–kidney transplantation reported in The Lancet in 1984,1 this procedure has evolved into a preferred treatment for patients with end-stage liver disease and end-stage kidney disease. Since the Model for End-stage…
[Comment] Winner of the 2024 Wakley Prize Essay: a deeper kind of caring
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02714-4/fulltext?rss=yes
Published: December 21, 2024 00:00
For the 2024 Wakley Prize Essay we invited submissions on any clinical topic of importance to health and particularly encouraged entries that reflect on the act of caring in medicine.1 In the call for submissions we noted how “Medicine is a caring…
[World Report] The Warnock Report: 40 years on
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02787-9/fulltext?rss=yes
Published: December 21, 2024 00:00
Published in 1984, the Warnock Report gave the embryo a “special status”, enabling medical research. As science and society develops, there are new challenges. Jacqui Thornton reports.
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02753-3/fulltext?rss=yes
Published: December 21, 2024 00:00
Andersen BK, Sejr-Hansen M, Maillard L, et al. Quantitative flow ratio versus fractional flow reserve for coronary revascularisation guidance (FAVOR III Europe): a multicentre, randomised, non-inferiority trial. Lancet 2024; 404: 1835–46—In this Article,…
[Correspondence] Another claw hand in a Renaissance portrait
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02373-0/fulltext?rss=yes
Published: December 21, 2024 00:00
The medical knowledge of Renaissance artists, honed through the study of classical texts and direct anatomical exploration (including autopsies and early scientific observations), played a surprisingly crucial role in advancing the understanding of human…
[Perspectives] Highlights 2024: diverse insights and perspectives on health stories
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02718-1/fulltext?rss=yes
Published: December 21, 2024 00:00
In this issue of The Lancet we feature 30 photographs selected from the many interesting images that were entered for this year's Highlights photography competition. The winning images offer different insights and perspectives on health stories from a…
[Correspondence] Physician associates, competence expansion, and general practitioner burnout
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02606-0/fulltext?rss=yes
Published: December 21, 2024 00:00
Jessamy Bagenal's argument in support of p-hysician associates in primary care1 overlooks the effect of such competence expansion of non-general practitioners on general practitioner workloads and, ultimately, general practitioner burnout. Burnout among…
[Wakley Prize Essay] Physical findings
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02627-8/fulltext?rss=yes
Published: December 21, 2024 00:00
I spent most of my 2010 wedding day in the emergency ward of my local hospital. Instead of exchanging vows, I was desperately trying to convince the doctors there not to call elder protective services regarding the woman who was about to become my…
[Correspondence] Top ten menopause research priorities
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02602-3/fulltext?rss=yes
Published: December 21, 2024 00:00
Most people with functioning ovaries will eventually go through menopause. However, the research priorities for those with lived experience of menopause and their health-care providers is not known.1 A James Lind Alliance Priority Setting Partnership is a…
[Clinical Picture] Abscopal response in a patient with fibrolamellar hepatocellular carcinoma following radiotherapy
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02600-X/fulltext?rss=yes
Published: December 21, 2024 00:00
A 17-year-old child with fibrolamellar hepatocellular carcinoma presented for treatment of recurrence in the right hilum and bilateral lungs discovered during routine surveillance imaging; he had reported no symptoms.The patient was first diagnosed at 13…
[Correspondence] End non-consensual surgeries on intersex children in Serbia
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02535-2/fulltext?rss=yes
Published: December 21, 2024 00:00
A report from October, 2024,1 on sex normalisation surgeries for intersex children in Serbia exposed an urgent human rights crisis. Serbian doctors claim that these procedures prevent trauma, but extensive evidence2 shows that non-consensual sex…
[World Report] TĂĽrkiye rocked by newborn care scandal
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02788-0/fulltext?rss=yes
Published: December 21, 2024 00:00
A huge criminal investigation is under way following accusations that fraud and substandard care have resulted in the deaths of several babies. Kaya Genc reports from Istanbul.
[Correspondence] Extended optical treatment for children with amblyopia in Europe: the EuPatch trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02234-7/fulltext?rss=yes
Published: December 14, 2024 00:00
We would like to express our appreciation for the substantial contribution made by Frank A Proudlock and colleagues in their comparative analysis of extended optical treatment and early patching regimens’ efficacy in treating childhood amblyopia.1…
[World Report] Smog once again plagues India and Pakistan
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02711-9/fulltext?rss=yes
Published: December 14, 2024 00:00
Air pollution is having extremely harmful health effects in south Asia. Why is the problem so bad? And what can be done about it? Talha Burki reports.
[Perspectives] A feminist psychiatry
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02672-2/fulltext?rss=yes
Published: December 14, 2024 00:00
During the 1980s in some health-care settings in the UK an acronym started appearing in medical notes, or rather, in women's medical notes: TATT CC AAO. Many doctors were trying to get the “tired all the time, can’t cope, aching all over” patients out of…
[Perspectives] Emma Rawson-Te Patu: decolonising public health globally
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02671-0/fulltext?rss=yes
Published: December 14, 2024 00:00
In the spring of 2024, Emma Rawson-Te Patu became the first Indigenous person to serve as President of the civil society organisation the World Federation of Public Health Associations (WFPHA). Before that, Rawson-Te Patu, who describes herself as a…
[Comment] Catching smoke: the rising and unequal burden of landscape fires on global health
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02525-X/fulltext?rss=yes
Published: December 14, 2024 00:00
Landscape fires occur on every continent except Antarctica.1 While some fires have devasting effects on local communities, more than two billion people around the world are also affected by air pollution produced by these fires, also known as smoke…
[Perspectives] On paying attention
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02673-4/fulltext?rss=yes
Published: December 14, 2024 00:00
Coined in 1971 by Nobel laureate economist Herbert A Simon, the term “attention economy” describes attention as a most valuable and limited resource. In this zero-sum game, the growing “wealth of information means the dearth of something else” or, as Simon…
[Clinical Picture] Sarcoidosis of the pituitary gland and stalk in a man presenting asthenia, impotence, loss of libido, polyuria, and polydipsia
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02556-X/fulltext?rss=yes
Published: December 14, 2024 00:00
A 36-year-old man with a 6-month history of asthenia, impotence, loss of libido, polyuria, and polydipsia attended our department; he also reported needing to wake up twice at night to urinate and Raynaud's phenomenon. The patient had a medical history of…
[Correspondence] Neurocysticercosis school outbreak in Belgium
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02356-0/fulltext?rss=yes
Published: December 14, 2024 00:00
Human cysticercosis results from ingesting microscopic Taenia solium eggs shed by a tapeworm carrier, forming cystic larvae (ie, cysticerci) in tissues. These larvae normally encyst in the pig, the natural intermediate host. Upon consumption by humans,…
[Correspondence] Extended optical treatment for children with amblyopia in Europe: the EuPatch trial – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02235-9/fulltext?rss=yes
Published: December 14, 2024 00:00
We thank Catherine Stewart and colleagues and Yue Li and Guangsen Liu for their comments. Their work over 25 years, advocating personalised treatment with age-adjusted patching durations and extended optical treatment, represents important contributions.…
[Editorial] Health in Ukraine amid great uncertainty
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02712-0/fulltext?rss=yes
Published: December 14, 2024 00:00
More than 1000 days of deaths, destruction, fear, displacement, separation, hunger, and trauma have passed since the full-scale invasion of Ukraine by Russia. The UN estimates that in 2024, 14·6 million people in Ukraine needed humanitarian assistance…
[World Report] What will new assisted dying legislation mean for doctors?
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02710-7/fulltext?rss=yes
Published: December 14, 2024 00:00
Members of Parliament have backed a bill to legalise assisted dying in England and Wales, paving the way for a fundamental shift in doctors’ practice. Jacqui Thornton reports.
[Correspondence] Extended optical treatment for children with amblyopia in Europe: the EuPatch trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02233-5/fulltext?rss=yes
Published: December 14, 2024 00:00
The most common form of amblyopia therapy comprises two components: glasses wear (optical treatment) and occlusion (patching) of the unaffected eye. Historically prescribed concurrently but now consecutively, initial glasses wear of typically 18 weeks will…
[World Report] New EU Health Commissioner appointed amid controversy
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02709-0/fulltext?rss=yes
Published: December 14, 2024 00:00
Olivér Várhelyi's tempestuous confirmation process has seen pandemic preparedness and reproductive health stripped from his portfolio. Marianne Guenot reports.