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The Lancet RSS feed.
Site URL: www.thelancet.com/journals/lancet/issue/current
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Posts: 50
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[Correspondence] The Changing Mindsets Initiative
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00578-1/fulltext?rss=yes
Published: May 10, 2025 00:00
The past 50 years have seen remarkable improvements in health globally. But people in lower-income majority world countries still have poorer health and health care than those in much higher-income minority world countries. This disparity is sustained in…
[Correspondence] Intimate partner violence and ART adherence in Uganda
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00580-X/fulltext?rss=yes
Published: May 10, 2025 00:00
Globally, an estimated 3·4 million young people aged 15–24 years are living with HIV, two-thirds of whom reside in sub-Saharan Africa.1 Uganda, for instance, has one of the highest HIV prevalence rates among young people, with adolescent girls and young…
[Correspondence] Safety of intranasally administered etripamil: RAPID trial update
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00545-8/fulltext?rss=yes
Published: May 10, 2025 00:00
We are writing to provide further detail on adverse event findings presented in our Lancet publication on the RAPID trial.1 Etripamil is a fast-acting, intranasally administered calcium-channel blocker in development for on-demand therapy outside of a…
[Correspondence] Isotretinoin-associated cervical osteophytosis – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00496-9/fulltext?rss=yes
Published: May 10, 2025 00:00
We thank Huang Chang-Quan for his interest in our recent Clinical Picture1 and the relevant points raised. As suggested, we did indeed consider diffuse idiopathic skeletal hyperostosis (DISH) as one of the main differential diagnoses because our patient…
[Correspondence] Positive RPR and TPLA tests cannot confirm congenital syphilis
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00360-5/fulltext?rss=yes
Published: May 10, 2025 00:00
We appreciate Tomoaki Hirate and colleagues1 for sharing a case of congenital syphilis. However, we must clarify that the assertion that “both mother and child were positive on RPR [rapid plasma reagin] and TPLA [Treponema pallidium latex assay]…
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00903-1/fulltext?rss=yes
Published: May 10, 2025 00:00
Bossi A, Foulon S, Maldonado X, et al. Efficacy and safety of prostate radiotherapy in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 × 2 factorial design. Lancet 2024; 404:…
[Correspondence] Triple crisis among refugee youth resettled in high-income countries
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00581-1/fulltext?rss=yes
Published: May 10, 2025 00:00
In the past 10 years, youth from refugee families resettled in high-income countries, including the USA, Canada, and Australia, have been dying at unprecedented rates from the triple crisis of suicide, drug and alcohol overdose, and youth violence.1–3…
[World Report] Trump works towards US tariffs on drug imports
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00982-1/fulltext?rss=yes
Published: May 10, 2025 00:00
Observers warn of the negative health consequences if US President Donald Trump follows through on his promise to impose tariffs on pharmaceuticals. Susan Jaffe reports.
[Correspondence] Positive RPR and TPLA tests cannot confirm congenital syphilis – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00361-7/fulltext?rss=yes
Published: May 10, 2025 00:00
We would like to thank Xin Yu Yang and colleagues for their interest in our Clinical Picture1 and for highlighting the diagnostic challenges of congenital syphilis in their comments.
[World Report] US AI regulatory rollback and health
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00980-8/fulltext?rss=yes
Published: May 10, 2025 00:00
Donald Trump has promised to create a pro-AI environment, but even tech companies are frustrated by federal cuts that hamper regulatory processes. Paul Webster reports.
[Correspondence] Isotretinoin-associated cervical osteophytosis
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00495-7/fulltext?rss=yes
Published: May 10, 2025 00:00
The Clinical Picture by Kamran Naraghi and Helena Marzo-Ortega1 highlights an unusual case of cervical osteophytosis linked to the long-term use of isotretinoin, which was prescribed to treat rosacea. However, questions remain regarding the causal…
[Editorial] 50 years of SSRIs: weighing benefits and harms
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00981-X/fulltext?rss=yes
Published: May 10, 2025 00:00
More than 50 years have passed since the discovery of fluoxetine, better known by its trade name Prozac. Together with the development of several other compounds, collectively known as selective serotonin reuptake inhibitors (SSRIs), fluoxetine transformed…
[Correspondence] The impact of US tariff hikes on health care
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00779-2/fulltext?rss=yes
Published: April 29, 2025 22:30
The recent escalation of US trade policies, characterised by steep tariff increases on imports from China and other nations,1 threatens to destabilise not only global supply chains but also public health systems worldwide. US President Donald Trump…
[Correspondence] USA–China tariffs on pharmaceuticals affect global health equity
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00780-9/fulltext?rss=yes
Published: April 29, 2025 22:30
US President Donald Trump's decision to impose punitive tariffs of 145% for pharmaceutical imports from China,1 effective since April 10, 2025, will pose substantial challenges towards global health security, marking an evolution in the trade tiff between…
[Correspondence] Cholera risk in Goma, DR Congo, after forced clearing of relief camps
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00658-0/fulltext?rss=yes
Published: April 29, 2025 22:30
The emerging crisis in eastern DR Congo and especially around the city of Goma, in the province of North Kivu, has worrying implications for cholera in the region. The area around Goma has been tumultuous since 2021 because of a volcanic eruption, followed…
[Obituary] Pippa Tyrrell
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00772-X/fulltext?rss=yes
Published: April 26, 2025 00:00
Neurologist who developed an integrated model of care for stroke in the UK and saw it become the standard of care nationwide. She was born in Sheffield, UK, on Sept 10, 1956, and died of bowel cancer at home in Wilmslow, UK, on Jan 1, 2025, aged 68 years.
[World Report] NIH access bans imperil global scientific cooperation
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00818-9/fulltext?rss=yes
Published: April 26, 2025 00:00
Six countries, including China, have been banned from key data repositories. Bryant Furlow reports.
[Correspondence] Research at the centre of UK health-care delivery to fix clinical academia
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00493-3/fulltext?rss=yes
Published: April 26, 2025 00:00
Clinical academia is on a steep decline globally. In the UK, a 6% reduction in the number of clinical academics since 2012 has been reported, with the number of senior lecturer level researchers having decreased by 24%.1 Research is key to evidence-based…
[Correspondence] Ticagrelor monotherapy for acute coronary syndromes
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00364-2/fulltext?rss=yes
Published: April 26, 2025 00:00
I read with great interest the Article by Marco Valgimigli and colleagues.1 The study provides valuable insights into balancing ischaemic protection and bleeding risks, especially in patients with acute coronary syndromes (ACS) and non-ACS. I would like to…
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00776-7/fulltext?rss=yes
Published: April 26, 2025 00:00
Amouzou A, Barros AJD, Requejo J, et al. The 2025 report of the Lancet Countdown to 2030 for women's, children's, and adolescents’ health: tracking progress on health and nutrition. Lancet 2025; 405: 1505–54—In this Review, Abdoulaye Maïga was missing from…
[Perspectives] On going backwards
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00771-8/fulltext?rss=yes
Published: April 26, 2025 00:00
There are patients you can never forget. Some because you connected unusually deeply with them as people or with their stories—some because you may have seen yourself or a loved one in their shoes, on that gurney, in that pain. On a paediatric rotation as…
[Correspondence] Ticagrelor monotherapy for acute coronary syndromes
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00362-9/fulltext?rss=yes
Published: April 26, 2025 00:00
We read with interest the Article by Marco Valgimigli and colleagues comparing dual antiplatelet therapy (DAPT) de-escalation to ticagrelor monotherapy versus continuing DAPT for 12 months after coronary drug-eluting stent implantation.1 The authors…
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00775-5/fulltext?rss=yes
Published: April 26, 2025 00:00
Hu X, Zhang J, Yang S, et al. Angiography-derived fractional flow reserve versus intravascular ultrasound to guide percutaneous coronary intervention in patients with coronary artery disease (FLAVOUR II): a multicentre, randomised, non inferiority trial.…
[World Report] The medicine of…competitive eating
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00820-7/fulltext?rss=yes
Published: April 26, 2025 00:00
In our continuing series on medicine in unusual circumstances, Talha Burki gets a taste of the world of competitive eating.
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00767-6/fulltext?rss=yes
Published: April 26, 2025 00:00
Strunk T, Molloy EJ, Mishra A, Bhutta ZA. Neonatal bacterial sepsis. Lancet 2024; 404: 277–93—In figure 1 of this Seminar, the teal key title has been updated to “Other neonatal disorders”. This correction has been made to the online version as of April…
[World Report] Can the FDA fulfil its mission with a smaller workforce?
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00819-0/fulltext?rss=yes
Published: April 26, 2025 00:00
The US Food and Drug Administration's new commissioner promises to restore public trust despite mass layoffs. Washington Correspondent Susan Jaffe reports.
[Correspondence] Pretransplantation optimisation for unresectable colorectal liver metastases: the TransMet trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00661-0/fulltext?rss=yes
Published: April 26, 2025 00:00
We read the Article on the TransMet trial by René Adam and colleagues with great enthusiasm.1 The results are unprecedented, with a staggering 5-year overall survival of 56·6% (95% CI 43·2−74·1) in the liver transplantation plus chemotherapy group compared…
[Correspondence] Pretransplantation optimisation for unresectable colorectal liver metastases: the TransMet trial – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00660-9/fulltext?rss=yes
Published: April 26, 2025 00:00
We thank Akhil Santhosh and colleagues, Dimitrios Moris and colleagues, and Shouhui Yi and colleagues for their positive comments and relevant questions about the practice-changing TransMet trial.1
[Correspondence] Ticagrelor monotherapy for acute coronary syndromes
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00363-0/fulltext?rss=yes
Published: April 26, 2025 00:00
One of the key concerns in the Article by Marco Valgimigli and colleagues is the ambiguity in defining the non-inferiority margin for major adverse cardiovascular or cerebrovascular events (MACCE).1 The study sets a non-inferiority margin of 1·15 for the…
[Correspondence] Pretransplantation optimisation for unresectable colorectal liver metastases: the TransMet trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00663-4/fulltext?rss=yes
Published: April 26, 2025 00:00
We read with great interest the results of the TransMet trial1 by René Adam and colleagues showing that the combination of liver transplantation and chemotherapy prolongs survival in patients with colorectal liver metastases and, in some cases, can provide…
[Correspondence] Ticagrelor monotherapy for acute coronary syndromes – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00365-4/fulltext?rss=yes
Published: April 26, 2025 00:00
We thank our colleagues for their interest in our Article.1 Chunguang Guo and colleagues state that a non-inferiority margin of 1·15 means that the study would deem ticagrelor monotherapy acceptable even if it increased the major adverse cardiovascular or…
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00768-8/fulltext?rss=yes
Published: April 26, 2025 00:00
Buonfrate D, Ferrari TCA, Adegnika AA, Russell Stothard J, Gobbi FG. Human schistosomiasis. Lancet 2025; 405: 658–70—In this Seminar, Ayola Akim Adegnika's name should have appeared as Prof A A Adegnika in the affiliations. This correction has been made to…
[Correspondence] Pretransplantation optimisation for unresectable colorectal liver metastases: the TransMet trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00662-2/fulltext?rss=yes
Published: April 26, 2025 00:00
We read with great interest the Article on the TransMet trial by René Adam and colleagues.1 This multicentre randomised controlled trial provides robust evidence supporting the benefits of liver transplantation for patients with unresectable colorectal…
[Correspondence] Taiwan's national health care on the brink of systemic collapse
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00489-1/fulltext?rss=yes
Published: April 26, 2025 00:00
In early 2025, Taiwan's health-care system faced an unprecedented crisis due to simultaneous outbreaks of influenza and norovirus. The emergency departments had severe overcrowding, which was exacerbated by a shortage of ward beds. A patient died of septic…
[Editorial] Supporting medical science in the USA
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00814-1/fulltext?rss=yes
Published: April 26, 2025 00:00
The pursuit of rigorous medical science is not compatible with capitulation to government demands aimed at weaponising and eroding science. On April 14, Edwin R Martin Jr, the Trump-appointed interim US attorney for the District of Columbia, sent a letter…
[World Report] Humanitarians warn over assistance for mine victims
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00763-9/fulltext?rss=yes
Published: April 19, 2025 00:00
Funding cuts threaten support for victims, while several countries are withdrawing from a treaty that bans the use of indiscriminate weapons such as mines. John Zarocostas reports.
[World Report] After release, another struggle: Syria's ex-detainees
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00762-7/fulltext?rss=yes
Published: April 19, 2025 00:00
Syria's society and health-care sector are unable to meet the needs of thousands recently released from Assad's detention centres. Cosette Molijn reports.
[Perspectives] My autistic meltdown: the impact of autistic sensory needs
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00732-9/fulltext?rss=yes
Published: April 19, 2025 00:00
As an autistic adult, even the word meltdown is humiliating. A shameful part of my past, no longer relevant to a senior doctor, or so I would like to think. And yet the reality is different. Some 2 years on, tears threaten when I recall what happened. It…
[Correspondence] Irrigation efficacy in CSDH surgery: the FINISH trial – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00332-0/fulltext?rss=yes
Published: April 19, 2025 00:00
We thank Aaron Lawson McLean for their interest in the FINISH trial.1
[World Report] Aid cuts prompting a shift in migration policy
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00764-0/fulltext?rss=yes
Published: April 19, 2025 00:00
Countries are cutting funding and focusing more on regional efforts to deter migration rather than humanitarian relief. Sharmila Devi reports.
[Comment] Safety and immunogenicity of a virus-like particle Chikungunya virus vaccine
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00571-9/fulltext?rss=yes
Published: April 19, 2025 00:00
Chikungunya virus epidemics can be explosive and unpredictable, such as the 2015 outbreak in Brazil, which led to an estimated 1 million cases.1 Although only 620 000 cases were reported worldwide last year, approximately 4 billion people live in areas at…
[Correspondence] The need for expansion of global collaborations on AI in oncology
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00634-8/fulltext?rss=yes
Published: April 19, 2025 00:00
Over the past decade, artificial intelligence (AI) has made great progress in addressing unmet clinical needs in oncology and has emerged as a potential game changer.1 High-dimensional datasets, advances in high-performance computing, and innovative deep…
[Correspondence] Irrigation efficacy in CSDH surgery: the FINISH trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00331-9/fulltext?rss=yes
Published: April 19, 2025 00:00
The FINISH trial by Rahul Raj and colleagues offers key insights into the surgical management of chronic subdural haematoma (CSDH) by evaluating the efficacy of irrigation during burr-hole drainage.1 This study shows that irrigation can reduce reoperation…
[Obituary] Susan Franklin Wood
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00733-0/fulltext?rss=yes
Published: April 19, 2025 00:00
Influential health policy expert who focused on women's health. Born on Nov 5, 1958, in Jacksonville, FL, USA, she died of brain cancer glioblastoma multiforme on Jan 17, 2025, in London, UK, aged 66 years.
[Correspondence] Medical research funding cuts will save money and spend lives
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00544-6/fulltext?rss=yes
Published: April 19, 2025 00:00
Recent budget cuts to organisations central to US and international health—for example, the National Institutes of Health (NIH), the Food and Drug Administration (FDA), and the Centers for Disease Control and Prevention (CDC)—threaten medical research and…
[Correspondence] Population health and a representative US health-care workforce
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00659-2/fulltext?rss=yes
Published: April 19, 2025 00:00
Programmes to build a more representative US health-care workforce are under attack, despite the long-standing under-representation of health-care providers from racially and ethnically minoritised groups and evidence that a representative health-care…
[Correspondence] Need for VA-ECMO after heart transplantation with HOPE
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00358-7/fulltext?rss=yes
Published: April 19, 2025 00:00
We have read with interest the Article by Filip Rega and colleagues1 on the use of hypothermic oxygenated perfusion (HOPE) for the donor heart in heart transplantation. This trial provides evidence of the benefits of HOPE compared with static cold storage…
[Correspondence] Finalising the WHO Pandemic Agreement for a safer future
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00656-7/fulltext?rss=yes
Published: April 19, 2025 00:00
In December, 2021, all 194 Member States of WHO decided to establish the Intergovernmental Negotiating Body (INB) to draft and negotiate a convention, agreement, or other international instrument on pandemic prevention, preparedness, and response under…
[Correspondence] Need for VA-ECMO after heart transplantation with HOPE – Authors' reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00359-9/fulltext?rss=yes
Published: April 19, 2025 00:00
We thank Jose Gonzalez-Costello and colleagues for reviewing our trial report1 and appreciate the opportunity to address their comments. We acknowledge the observation regarding venoarterial extracorporeal membrane oxygenation (VA-ECMO) use in the…
[Correspondence] Rehabilitation under fire: insights from SUMC
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00412-X/fulltext?rss=yes
Published: April 19, 2025 00:00
Advancements in rehabilitation medicine and war are closely linked, with modern medicine improving survival rates for both soldiers and civilians.1 However, survival is just the beginning, and rehabilitation medicine has become increasingly important.…