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[Correspondence] Physical activity and exercise training in patients with HFrEF ā Authorsā reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01542-4/fulltext?rss=yes
Published: September 19, 2026 00:00
We thank Tim KambiÄ and colleagues for their Correspondence regarding the importance of exercise and physical activity for patients with heart failure with reduced ejection fraction (HFrEF).
[Perspectives] Waleska Teixeira Caiaffa: shaping healthier cities
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01871-4/fulltext?rss=yes
Published: September 19, 2026 00:00
In 1974, as the Brazilian student resistance movement strengthened against repression by the country's authoritarian government, Waleska Teixeira Caiaffa became a medical student at the Federal University of Minas Gerais in Brazil. The university wasā¦
[Correspondence] Unmasking inequity: emergency presentations in ovarian cancer care ā Authorsā reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01543-6/fulltext?rss=yes
Published: September 19, 2026 00:00
We thank Rui Wu and colleagues for their thoughtful commentary on the outlined objectives for the Lancet Commission on Ovarian Cancer.1 The authors have provided intriguing data regarding the percentage of women who are first diagnosed in emergency roomā¦
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01874-X/fulltext?rss=yes
Published: September 19, 2026 00:00
Hatter L, Holliday M, Oldfield K, et al. Budesonideāformoterol versus salbutamol as reliever therapy in children with mild asthma (CARE): a 52-week, open-label, multicentre, superiority, randomised controlled trial. Lancet 2025; 406: 1473ā83āIn thisā¦
[Correspondence] The Italian model of screening for CKD
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01586-2/fulltext?rss=yes
Published: September 19, 2026 00:00
Tonelli and colleagues should be commended for their recently published Health Policy.1 This advocacy paper will indeed profoundly change the vision of nephrology practice on chronic kidney disease (CKD). The paper itemises the major steps towards a majorā¦
[Editorial] The unmet needs of people living with severe asthma
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01904-5/fulltext?rss=yes
Published: September 19, 2026 00:00
More than 260 million people worldwide live with asthma, and more than 400ā000 die of the disease each year. 5ā10% of people with asthma live with severe asthma, but it has an outsized effectāfrequent disease exacerbations, poor lung function, and aā¦
[Obituary] Vadim Pokrovsky
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01873-8/fulltext?rss=yes
Published: September 19, 2026 00:00
Epidemiologist and leading HIV specialist in Russia. Born on Jan 17, 1955, in Moscow, Russia, he died on May 20, 2026, in Moscow, aged 71 years.
[Correspondence] Making rehabilitation indicators disability-inclusive
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01718-6/fulltext?rss=yes
Published: September 19, 2026 00:00
Global efforts to strengthen rehabilitation systems are urgently needed. The WHO Rehabilitation 2030 initiative and its work to develop standardised rehabilitation indicators1 are therefore important steps towards improving rehabilitation services andā¦
[Correspondence] Patient organisations are key implementation partners
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01587-4/fulltext?rss=yes
Published: September 19, 2026 00:00
As President of the Mario Robles Ossio Foundation, a Mexican patient organisation, I strongly support the focus on implementation in the Health Policy by Tonelli and colleagues.1 Mexico has one of the highest burdens of kidney disease worldwide. In March,ā¦
[Perspectives] Why medicine needs philosophy of medicine
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01877-5/fulltext?rss=yes
Published: September 19, 2026 00:00
The starting point for medicine is accurate knowledge of the body. These words belong to the renowned 2nd-century physician Galen. However, as revealed by the title of their text, The Best Physician is Also a Philosopher, Galen argued that a true followerā¦
[Correspondence] Platinum-resistant ovarian cancers: lessons from KEYNOTE-B96 ā Authorsā reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01592-8/fulltext?rss=yes
Published: September 19, 2026 00:00
We thank Stanislas Quesada and colleagues for their thoughtful comments and for recognising the clinically meaningful benefit of pembrolizumab plus weekly paclitaxel, with or without bevacizumab, in platinum-resistant ovarian cancer.1 Becauseā¦
[Comment] Offline: The emptiness of the quantified self
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01869-6/fulltext?rss=yes
Published: September 19, 2026 00:00
Byung-Chul Han's short book, Psychopolitics: Neoliberalism and New Technologies of Power (2025, first published in German in 2014), opens with a line that should make us all pause: āFreedom will prove to have been merely an interlude.ā End-of argumentsā¦
[Correspondence] Physical activity and exercise training in patients with HFrEF
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00696-3/fulltext?rss=yes
Published: September 19, 2026 00:00
We read with great interest the Seminar by Antonio Cannata and colleagues1 on novel diagnosis and management approaches to heart failure with reduced ejection fraction (HFrEF). We were surprised by the omission of recent guideline-recommended regularā¦
[Correspondence] Platinum-resistant ovarian cancers: lessons from KEYNOTE-B96
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01205-5/fulltext?rss=yes
Published: September 19, 2026 00:00
We congratulate Nicoletta Colombo and colleagues for the practice changing results of the ENGOT-ov65/KEYNOTE-B96 trial in platinum-resistant ovarian cancer.1 Their study reports clinically significant improvement in progression-free survival and clinicallyā¦
[Perspectives] The battle for better mental health systems needs us all
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01872-6/fulltext?rss=yes
Published: September 19, 2026 00:00
When I was in my late 20s I stood on a bridge for a very long time. I was there, for many reasons. Fatigue being the greatest among them. This tiredness was not only caused by lack of sleep but also from exhaustion linked to 2 years spent as a Black womanā¦
[Correspondence] Unmasking inequity: emergency presentations in ovarian cancer care
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00848-2/fulltext?rss=yes
Published: September 19, 2026 00:00
We highly commend Isabelle Ray-Coquard and colleagues for their Comment announcing the Lancet Commission on Ovarian Cancer,1 emphasising equity-driven reform. However, we believe they overlook a crucial barrier to improving population-level survival:ā¦
[Perspectives] Tim Baker: bringing systems change to acute health-care provision
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01823-4/fulltext?rss=yes
Published: September 12, 2026 00:00
āGlobal health has traditionally focused on health promotion and preventing diseaseā, says Tim Baker, Associate Professor at Muhimbili University of Health and Allied Sciences in Dar es Salaam, Tanzania. āBut some people will get sick, and many becomeā¦
[Editorial] Gene-editing therapies: delivering safely for patients
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01858-1/fulltext?rss=yes
Published: September 12, 2026 00:00
āThe pain I would feel in my body was like being struck by lightning and hit by a freight train all at once.ā Victoria Gray's words will resonate with anyone who has experienced a sickle-cell disease crisis. In 2019, she became the first patient to haveā¦
[Correspondence] Inverting power must begin with authorship
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01509-6/fulltext?rss=yes
Published: September 12, 2026 00:00
The Johns Hopkins Centre for Humanitarian HealthāLancet Commission by Paul Spiegel and colleagues1 makes a claim that is both correct and overdue: the humanitarian system requires structural transformation, not incremental reform, and that transformationā¦
[Correspondence] Humanitarian lessons from UNRWA's experience in Gaza
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01512-6/fulltext?rss=yes
Published: September 12, 2026 00:00
The Johns Hopkins Center for Humanitarian HealthāLancet Commission by Paul Spiegel and colleagues1 argues that the current humanitarian system is no longer fit for purpose. It identifies four recommendations: invert the power, end impunity, fix the money,ā¦
[Correspondence] Global science to promote cooperation and understanding
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01697-1/fulltext?rss=yes
Published: September 12, 2026 00:00
The idea that science might promote cooperation could sound naive in a world beset by war, sanctions, strategic rivalry, and institutional breakdown. Science cannot stop armies or resolve diplomatic failures. When formal political institutions weaken,ā¦
[Perspectives] A positive difference: unimagined communities, reimagined research
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01824-6/fulltext?rss=yes
Published: September 12, 2026 00:00
Existing narratives around race and ethnicity in medicine are overwhelmingly negative. Historians have documented overt bias and outright exploitation of Black and Brown people. Social scientists and policy researchers routinely evidence the harmfulā¦
[Department of Error] Department of Error
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01822-2/fulltext?rss=yes
Published: September 12, 2026 00:00
Shen L, Zhang X, Ji K, et al. Perioperative serplulimab with neoadjuvant chemotherapy versus perioperative chemotherapy in PD-L1-positive gastric cancer (ASTRUM-006): a randomised, double-blind, multicentre, phase 3 study. Lancet 2026; 407: 2542ā53āIn thisā¦
[Articles] Efficacy and safety of mitapivat in adults with transfusion-dependent α-thalassaemia or β-thalassaemia (ENERGIZE-T): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00874-3/fulltext?rss=yes
Published: September 12, 2026 00:00
Mitapivat significantly reduced the transfusion burden and was generally well tolerated, showing a favourable benefitārisk profile. These findings support mitapivat as the first oral disease-modifying therapy for adults with transfusion-dependentā¦
[Comment] rVSVĪG-ZEBOV-GP vaccine-induced seroreactivity to Bundibugyo virus: a cross-protection dilemma
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01771-X/fulltext?rss=yes
Published: September 12, 2026 00:00
The virus family Filoviridae includes several species known to cause severe and often fatal disease in humans. Within the genus Orthoebolvirus, the majority of clinical disease cases and associated deaths have been caused by Orthoebolavirus zairense (Ebolaā¦
[Comment] Offline: The tragic fallacy of global health reform
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01853-2/fulltext?rss=yes
Published: September 12, 2026 00:00
In Jorge Luis Borges's fantastical short story, Tlƶn, Uqbar, Orbis Tertius, written in 1940, he imagines the invention of a new world, Tlƶn, by a secret society of, among others, astronomers, biologists, and engineers. Over several centuries, theyā¦
[Obituary] Maura L Gillison
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01825-8/fulltext?rss=yes
Published: September 12, 2026 00:00
Medical oncologist and scientist who defined the role of HPV in oropharyngeal cancer. Born on Jan 4, 1965, in London, ON, Canada, she died of small intestine cancer on June 21, 2026, in Willoughby, OH, USA, aged 61 years
[World Report] Conflict and inequality complicate Colombia earthquake relief
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01860-X/fulltext?rss=yes
Published: September 12, 2026 00:00
Health care in Chocó, the epicentre of the earthquake, was already under severe strain. Daniela DĆaz Rangel and Amy Booth report.
[Correspondence] Humanitarian crises are a hotbed for organ trafficking
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01510-2/fulltext?rss=yes
Published: September 12, 2026 00:00
Paul Spiegel and colleagues should be congratulated on their Commission related to health, conflict, and displacement in a world of crises and impunity.1
[World Report] Fears over longer term health impacts of Nepal floods
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01859-3/fulltext?rss=yes
Published: September 12, 2026 00:00
Experts warn of a risk of communicable diseases, malnutrition, and mental health conditions following catastrophic flooding that has killed thousands. Sophie Cousins reports.
[Correspondence] Inverting power must begin with authorship ā Authorsā reply
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01703-4/fulltext?rss=yes
Published: September 12, 2026 00:00
We thank Qusai Khraisha for a critique that is at once generous and exacting. We appreciate that the Commission's central claim1āthat transforming the humanitarian system is a question of power, of who decides, and on whose behalfāwas read as clear andā¦
[Comment] Mitapivat for transfusion-dependent α-thalassaemia and β-thalassaemia
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01609-0/fulltext?rss=yes
Published: September 12, 2026 00:00
Thalassaemias are the most common monogenic inherited diseases and are characterised by reduced production of globin chains of haemoglobin. The two most common forms are α-thalassaemia and β-thalassaemia, which affect the production of α-globin andā¦
[Correspondence] Naming palliative care in conflict and forced displacement
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01511-4/fulltext?rss=yes
Published: September 12, 2026 00:00
The Johns Hopkins Center for Humanitarian HealthāLancet Commission by Paul Spiegel and colleagues offers a compelling account of humanitarian system failure and its consequences for people affected by conflict and forced displacement.1 The Commission callsā¦
[Correspondence] Minority voices in conflict-affected health systems
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01508-4/fulltext?rss=yes
Published: September 12, 2026 00:00
We read with interest the Commission by Paul Speigel and colleagues1 and commend its timely and ambitious effort to advance health equity and address the structural drivers of poor health outcomes worldwide. At a moment when conflict, displacement,ā¦