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Nutrients, Vol. 17, Pages 1040: Evaluation of Inulin and Polyphenol Content and the Cytotoxicity of Cichorium intybus L. var. foliosum Root Extracts Obtained by Pectinase- and Pressure-Assisted Extraction

https://www.mdpi.com/2072-6643/17/6/1040

Published: March 16, 2025 00:00

Background: Cichorium intybus L., a member of the Asteraceae family, has numerous health-promoting properties that categorize its preparations as functional foods and herbal medicines. Most previous research focused on the root of C. intybus var. sativum…

Toxics, Vol. 13, Pages 215: Arsenic Exposure During Pregnancy and Childhood: Factors Explaining Changes over a Decade

https://www.mdpi.com/2305-6304/13/3/215

Published: March 16, 2025 00:00

Arsenic chronic exposure, particularly in its inorganic form, represents a significant public health concern. This study was conducted in Arica, the northernmost city in the country, whose inhabitants have been exposed to inorganic arsenic both naturally…

Diagnostics, Vol. 15, Pages 738: A Retrospective Study Regarding the Efficacy of Nuvola® OP Clear Aligners in Maxillary Arch Expansion in Adult Patients

https://www.mdpi.com/2075-4418/15/6/738

Published: March 16, 2025 00:00

Background/Objectives: The study evaluated the effectiveness of Nuvola® OP aligners, combined with an interceptive myofunctional device, in achieving dental arch expansions over an 18–26-month treatment period. Methods: 54 patients (31 women and…

Emergency Care and Medicine, Vol. 2, Pages 14: Canadian Emergency Physician Attitudes Toward Somatic Symptom and Related Disorders

https://www.mdpi.com/2813-7914/2/1/14

Published: March 16, 2025 00:00

Background: Somatic symptom disorder (SSD) involves physical symptoms that cannot entirely be explained by an organic medical cause, accompanied by persistent thoughts, feelings and behaviours relating to one’s health. SSD is common yet…

Sensors, Vol. 25, Pages 1842: An Identification Method for Road Hypnosis Based on XGBoost-HMM

https://www.mdpi.com/1424-8220/25/6/1842

Published: March 16, 2025 00:00

Human factors are the most important factor in road traffic crashes. Human-caused traffic crashes can be reduced through the active safety system of vehicles. Road hypnosis is an unconscious driving state caused by the combination of external environmental…

Materials, Vol. 18, Pages 1304: Influence of Pozzolanic Additives on the Structure and Properties of Ultra-High-Performance Concrete

https://www.mdpi.com/1996-1944/18/6/1304

Published: March 16, 2025 00:00

The aim of this paper is to analyse the influence of the following different supplementary cementitious materials (SCMs): milled quartz sand, microsilica, waste metakaolin, milled window glass, and a binary additive made of one part waste metakaolin and…

Molecules, Vol. 30, Pages 1328: Enzymatic Esterification of Functional Lipids for Specialty Fats: 1,3-Dipalmitoylglycerol and 1,3-Distearoylglycerol

https://www.mdpi.com/1420-3049/30/6/1328

Published: March 16, 2025 00:00

High-melting point 1,3-diacylglycerols not only provide health benefits, but are also suitable for manufacture of foods containing various specialty fats. It is difficult to prepare such high-melting point diacylglycerols, as the activities of specific…

Nanomaterials, Vol. 15, Pages 450: Development and Performance Study of Continuous Oil–Water Separation Device Based on Superhydrophobic/Oleophilic Mesh

https://www.mdpi.com/2079-4991/15/6/450

Published: March 16, 2025 00:00

Oil–water separation is an important method for treating oily wastewater and recovering oil resources. Based on the different affinities of superhydrophobic surfaces to water and oil, long-term oil–water separation devices with low-energy and…

Physchem, Vol. 5, Pages 12: Random Forest-Based Machine Learning Model Design for 21,700/5 Ah Lithium Cell Health Prediction Using Experimental Data

https://www.mdpi.com/2673-7167/5/1/12

Published: March 16, 2025 00:00

In this research, the use of machine learning techniques for predicting the state of health (SoH) of 5 Ah—21,700 lithium-ion cells were explored; data from an experimental aging test were used to build the prediction model. The main objective of this…

Water, Vol. 17, Pages 845: Rice Fields and Aquatic Insect Biodiversity in Italy: State of Knowledge and Perspectives in the Context of Global Change

https://www.mdpi.com/2073-4441/17/6/845

Published: March 15, 2025 00:00

Rice fields are one of the most important and extensive agro-ecosystems in the world. Italy is a major non-Asian rice producer, with a significant proportion of its yield originating from a vast area within the Po Valley, a region nourished by the waters…

Life, Vol. 15, Pages 468: The Influence of Microorganisms on the Onset and Development of Colorectal Cancer in Humans: A Descriptive Cross-Reference Study

https://www.mdpi.com/2075-1729/15/3/468

Published: March 15, 2025 00:00

Background: The aim of this study is to determine which types of microorganisms influence the onset and development of colorectal cancer (CRC) in humans. Methods: In patients with CRC, three swabs were taken for microbiological analysis during surgical…

Sensors, Vol. 25, Pages 1830: The Effects of Palmar Cooling on Repeated Sprinting Ability: A Randomized Controlled Clinical Trial

https://www.mdpi.com/1424-8220/25/6/1830

Published: March 15, 2025 00:00

Evidence supports the role of palmar cooling to improve exercise performance, especially with endurance and resistance activities. The aim of this randomized placebo-controlled trial was to explore the effects of palmar cooling on repeated sprinting…

Children, Vol. 12, Pages 365: Health-Related Quality of Life of Individuals with Physical Disabilities in Childhood

https://www.mdpi.com/2227-9067/12/3/365

Published: March 15, 2025 00:00

Background: The use of patient-reported outcomes is essential to understand and manage health-related quality of life (HRQOL) in youth with lifelong disabilities. This study evaluated HRQOL in youth with physical disorders and examined its relationship…

Life, Vol. 15, Pages 469: Interleukin 8 Molecular Interplay in Allergic Rhinitis and Chronic Rhinosinusitis with Nasal Polyps: A Scoping Review

https://www.mdpi.com/2075-1729/15/3/469

Published: March 15, 2025 00:00

The present scoping review underlines the molecular interplay between allergic rhinitis (AR), chronic rhinosinusitis with nasal polyps (CRSwNP), and interleukin-8 (IL-8). A query of PubMed database resulted in the inclusion of 34 articles in the final…

Minerals, Vol. 15, Pages 301: A 3D Geological Modeling Method Using the Transformer Model: A Solution for Sparse Borehole Data

https://www.mdpi.com/2075-163X/15/3/301

Published: March 15, 2025 00:00

Three-dimensional (3D) geological models are essential for geological analysis and mineral resource estimation. Although conventional on-site survey methods, such as boreholes, provide local engineering geological information for 3D geological modeling,…

Nanomaterials, Vol. 15, Pages 444: Mn2+-Doped CsPbBr2I Quantum Dots Photosensitive Films for High-Performance Photodetectors

https://www.mdpi.com/2079-4991/15/6/444

Published: March 15, 2025 00:00

The variable bandgap and high absorption coefficient of all-inorganic halide perovskite quantum dots (QDs), particularly CsPbBr2I make them highly promising for photodetector applications. However, their high defect density and poor stability limit their…

Polymers, Vol. 17, Pages 783: Processing of High-Performance Polymeric Materials: Modeling and Characterization

https://www.mdpi.com/2073-4360/17/6/783

Published: March 15, 2025 00:00

Polymers are an integral part of our world [...]

Cells, Vol. 14, Pages 433: Lysine Demethylase 1 Has Demethylase-Dependent and Non-Canonical Functions in Myofibroblast Activation in Systemic Sclerosis

https://www.mdpi.com/2073-4409/14/6/433

Published: March 14, 2025 00:00

Systemic sclerosis (SSc) is an autoimmune disease of unknown aetiology characterised by vasculopathy with progressive fibrosis of the skin and internal organs. Tissue fibrosis is driven by activated fibroblasts (myofibroblasts) with exacerbated contractile…

Applied Sciences, Vol. 15, Pages 3151: Investigation of Airborne Particulate Matter from a Holiday Celebration in Central Oklahoma Using an Unmanned Aerial Vehicle (UAV)

https://www.mdpi.com/2076-3417/15/6/3151

Published: March 14, 2025 00:00

Herein, a recently developed UAV/Drone approach as a new vector for the collection of airborne particulate matter is reported. In this study, airborne particle emissions from plumes generated in a holiday fireworks display were collected. A platform…

Nutrients, Vol. 17, Pages 1014: The Epithelial Barrier Hypothesis in Food Allergies: The State of the Art

https://www.mdpi.com/2072-6643/17/6/1014

Published: March 14, 2025 00:00

Recently, the “epithelial barrier hypothesis” has been proposed as a key factor in the development of allergic diseases, such as food allergies. Harmful environmental factors can damage epithelial barriers, with detrimental effects on the host…

Applied Sciences, Vol. 15, Pages 3153: Nonlinear Stability Analysis of Shallow-Buried Bias Tunnel Based on Failure Mode Improvement

https://www.mdpi.com/2076-3417/15/6/3153

Published: March 14, 2025 00:00

Based on the improvement of the Karl Terzaghi failure mode for calculating the surrounding rock pressure of loose rock mass, combined with the upper bound theorem of limit analysis, the formula for calculating the surrounding rock pressure of…

Cancers, Vol. 17, Pages 979: An Overview of Cellular and Molecular Determinants Regulating Chemoresistance in Pleural Mesothelioma

https://www.mdpi.com/2072-6694/17/6/979

Published: March 14, 2025 00:00

Malignant pleural mesothelioma (PM) is a highly aggressive disease of the lung pleura associated with poor prognosis. Despite advances in improving the clinical management of this malignancy, there is no effective chemotherapy for refractory or relapsing…

EJIHPE, Vol. 15, Pages 35: Responses to the AI Revolution in Hospitality and Tourism Higher Education: The Perception of Students Towards Accepting and Using Microsoft Copilot

https://www.mdpi.com/2254-9625/15/3/35

Published: March 14, 2025 00:00

This research aims to examine hospitality and tourism students’ acceptance and usage of Microsoft Copilot for educational purposes in Egyptian public universities. It also investigates the mediating role of behavioral intention (BI) in the connection…

Healthcare, Vol. 13, Pages 628: Validation of the Spanish Version of the Body Awareness Questionnaire (BAQ) and an Exploration of Its Relationship to Meditation and Embodiment Variables

https://www.mdpi.com/2227-9032/13/6/628

Published: March 14, 2025 00:00

Purposes: The Body Awareness Questionnaire (BAQ) has been considered the best available measure of body awareness, but it is not currently available in Spanish. Methods: To address this shortcoming, a sample of 281 Spanish participants completed a survey…

Biomolecules, Vol. 15, Pages 412: A Plasmid System That Utilises Phosphoribosylanthranilate Isomerase to Select Against Cells Expressing Truncated Proteins

https://www.mdpi.com/2218-273X/15/3/412

Published: March 14, 2025 00:00

We have generated a vector that enables the removal of plasmids coding for truncated proteins. This vector expresses a protein of interest in the yeast Saccharomyces cerevisiae from a galactose-inducible promoter. The gene of interest is fused in-frame to…

JRFM, Vol. 18, Pages 154: Crowdfunding Amidst FinTech Winter: Complement or Substitute?

https://www.mdpi.com/1911-8074/18/3/154

Published: March 14, 2025 00:00

This study examines the transformative potential of FinTech, particularly crowdfunding, in the context of traditional financial systems amidst the FinTech market downturn (‘Winter’) of 2022. We address a fundamental question: Does crowdfunding…

Grasses, Vol. 4, Pages 12: Accounting for Diurnal Variation in Enteric Methane Emissions from Growing Steers Under Grazing Conditions

https://www.mdpi.com/2813-3463/4/1/12

Published: March 14, 2025 00:00

Automated head chamber systems (AHCS) are increasingly deployed to measure enteric emissions in vivo. However, guidance for AHCS-derived emissions data analyses pertains to confined settings, such as feedlots, with less instruction for grazing systems.…

Buildings, Vol. 15, Pages 911: An Experimental Investigation of the Effects of Adding Polymer and Basalt Fibers on the Mechanical Properties and Durability of Lightweight Concrete

https://www.mdpi.com/2075-5309/15/6/911

Published: March 14, 2025 00:00

Despite extensive research on fiber-reinforced lightweight concrete, the synergistic effects of combining different types of fibers, such as polymer and basalt fibers, on the mechanical properties and durability of lightweight concrete have not been fully…

Buildings, Vol. 15, Pages 912: Study on Load-Bearing Characteristics and Engineering Applications for Cement–Soil Pipe Pile

https://www.mdpi.com/2075-5309/15/6/912

Published: March 14, 2025 00:00

The cement–soil pipe pile is a novel blend of cement and soil, designed to enhance load-bearing capabilities while cutting down on the need for cement. Its tubular construction is key to its strength. To delve into how the pile’s…

Coatings, Vol. 15, Pages 333: Cross-Scale Mechanical Contact Analysis from Asperities to Rough Surfaces: A Critical Review

https://www.mdpi.com/2079-6412/15/3/333

Published: March 14, 2025 00:00

Engineering equipment is an important material foundation for supporting national defense security and promoting the development of the national economy. Large and complex mechanical equipment has a complex structural composition and a large number of…

Quantum Reports, Vol. 7, Pages 12: Practical Implementation of Unconditionally Secure File Transfer Application with QKD and OTP

https://www.mdpi.com/2624-960X/7/1/12

Published: March 14, 2025 00:00

With the looming threat of quantum computers capable of breaking classical encryption and the uncertainty regarding the security of post-quantum encryption algorithms, some highly sensitive applications aim for the highest level of security in information…

Vaccines, Vol. 13, Pages 314: Anti-Tumor Efficacy of a Mesothelin-Based Nanovaccine in a KPC Orthotopic Mouse Model of Pancreatic Cancer

https://www.mdpi.com/2076-393X/13/3/314

Published: March 14, 2025 00:00

Background/Objectives: Immunotherapy has shown promising results in some cancers, but its efficacy remains limited in pancreatic ductal adenocarcinoma (PDAC). Vaccines in nanoparticle form (nanovaccines) can incorporate immunostimulating components to…

IJERPH, Vol. 22, Pages 424: Changes in Hand Hygiene Knowledge, Attitudes, and Practices Among Primary School Students: Insights from a Promotion Program in Guatemala

https://www.mdpi.com/1660-4601/22/3/424

Published: March 14, 2025 00:00

School-aged children are vulnerable to infectious diseases due to their developing immune systems and frequent social interactions. The COVID-19 pandemic underscored the importance of non-pharmaceutical interventions, like hand hygiene (HH). This study…

Toxins, Vol. 17, Pages 136: Innovations in Snake Venom-Derived Therapeutics: A Systematic Review of Global Patents and Their Pharmacological Applications

https://www.mdpi.com/2072-6651/17/3/136

Published: March 14, 2025 00:00

Active compounds from natural sources, particularly snake venoms, are crucial for pharmaceutical development despite challenges in drug discovery. Snake venoms, historically used for medicinal purposes, contain bioactive peptides and enzymes that show…

Diseases, Vol. 13, Pages 83: An Application for Spatial Frailty Models: An Exploration with Data on Fungal Sepsis in Neonates

https://www.mdpi.com/2079-9721/13/3/83

Published: March 14, 2025 00:00

Background: Globally, neonatal fungal sepsis (NFS) is a leading cause of neonatal mortality, particularly among vulnerable populations in neonatal intensive care units (NICU). The use of spatial frailty models with a Bayesian approach to identify hotspots…

Agronomy, Vol. 15, Pages 703: Assessing Agricultural Reuse Potential of Treated Wastewater: A Hybrid Machine Learning Approach

https://www.mdpi.com/2073-4395/15/3/703

Published: March 14, 2025 00:00

Estimating the quality of treated wastewater is a complex, nonlinear challenge that traditional statistical methods struggle to address. This study introduces a hybrid machine learning approach to predict key effluent parameters from an advanced biological…

Minerals, Vol. 15, Pages 296: Evolution of Permian Sedimentary Environment in South China: Constraints on Heterogeneous Accumulation of Organic Matter in Black Shales

https://www.mdpi.com/2075-163X/15/3/296

Published: March 14, 2025 00:00

Permian black shale, as a potential target for marine shale gas exploration in South China, is characterized by its great thickness and organic matter (OM) content. To understand the constraints on the heterogeneous accumulation of OM in Permian black…

Foods, Vol. 14, Pages 984: Factors Influencing the Intention to Eat Insects as an Alternative Protein Source: A Sample from Turkey

https://www.mdpi.com/2304-8158/14/6/984

Published: March 14, 2025 00:00

The consumption of insect-based foods has been widely studied in recent years due to their nutritional value and their contribution to sustainability. In this study, the integrated sustainable neophilic insect-based eating model (ISNIEM) was used to…

Polymers, Vol. 17, Pages 763: Efficient Bioprocess for Mixed PET Waste Depolymerization Using Crude Cutinase

https://www.mdpi.com/2073-4360/17/6/763

Published: March 14, 2025 00:00

In recent years, several plastic-degrading enzymes with efficient depolymerization abilities for PET have been reported. Here, we report a bioprocess for mixed PET waste depolymerization using crude extracellularly expressed enzymes in E. coli. The…

Cancers, Vol. 17, Pages 978: Pre- and Postnatal Exposures to Residential Pesticides and Survival of Childhood Acute Lymphoblastic Leukemia

https://www.mdpi.com/2072-6694/17/6/978

Published: March 14, 2025 00:00

Background: Exposure to pesticides has been associated with an increased risk of developing childhood leukemia. However, the impact of pesticides on childhood leukemia survival has not been examined. We investigated the associations between residential…

Antibiotics, Vol. 14, Pages 300: Community Pharmacists’ Responses Toward Antimicrobial Prescriptions in Jordan: A Cross-Sectional Survey

https://www.mdpi.com/2079-6382/14/3/300

Published: March 14, 2025 00:00

Background: Globally, community pharmacists worldwide have prescribed more over-the-counter systemic antibiotics, posing significant issues for international organizations tackling antibiotic-resistant bacteria, a major global threat, due to the…

Social Sciences, Vol. 14, Pages 175: Assessment of the Effectiveness of the Parenting Intervention Programme “Intelligent Families”: A Randomised Controlled Study

https://www.mdpi.com/2076-0760/14/3/175

Published: March 14, 2025 00:00

This study presents and analyses the effectiveness of the programme “Intelligent Families” aimed at promoting the development of parenting skills in parents within the framework of positive parenting. The popularity of attachment- and…

Algorithms, Vol. 18, Pages 166: A GNN-Based False Data Detection Scheme for Smart Grids

https://www.mdpi.com/1999-4893/18/3/166

Published: March 14, 2025 00:00

A Cyber-Physical System (CPS) incorporates communication dynamics and software into phsical processes, providing abstractions, modeling, design, and analytical techniques for the system. Based on spatial temporal graph neural networks (STGNNs), anomaly…

Commodities, Vol. 4, Pages 3: Secondhand Clothing in Global Commerce: Trade Patterns and Impact

https://www.mdpi.com/2813-2432/4/1/3

Published: March 14, 2025 00:00

Secondhand clothing has undergone a significant transformation from a vital household asset in the pre-industrial era to a dynamic segment of global trade in the 21st century. However, the advent of fast fashion has led to overproduction and mass…

Foods, Vol. 14, Pages 985: Study on the Effects of Tannase on the De Astringency of Pomegranate Juice

https://www.mdpi.com/2304-8158/14/6/985

Published: March 14, 2025 00:00

Reducing the punicalagin content is an effective strategy for eliminating the astringency of pomegranate juice. In this study, pomegranate juice was used as the raw material, and tannase was applied to convert punicalagin into ellagic acid and gallic acid.…

JMMS, Vol. 12, Pages 7: The Importance of Prenatal Whole-Exome Sequencing Testing in the Romanian Population

https://www.mdpi.com/2392-7674/12/1/7

Published: March 14, 2025 00:00

One major cause of prenatal mortality and morbidity is congenital abnormalities. Knowing the prevalence and etiology of congenital malformations is essential for analyzing trends and improving neonatal care. Objective: the team aimed to evaluate the…

Bioengineering, Vol. 12, Pages 290: Heart Sound Classification Based on Multi-Scale Feature Fusion and Channel Attention Module

https://www.mdpi.com/2306-5354/12/3/290

Published: March 14, 2025 00:00

Intelligent heart sound diagnosis based on Convolutional Neural Networks (CNN) has been attracting increasing attention due to its accuracy and efficiency, which have been improved by recent studies. However, the performance of CNN models, heavily…

Nitrogen, Vol. 6, Pages 17: Effects of Biochar, Biogas Slurry, and Dicyandiamide Application on N2O Emissions from Soil in Tomato Production Under Protected Cultivation

https://www.mdpi.com/2504-3129/6/1/17

Published: March 14, 2025 00:00

An experiment was conducted in spring 2024 to investigate the effects of biochar, biogas slurry, and dicyandiamide (DCD) on N2O emissions from soil in protected tomato cultivation. Five treatments were applied: conventional fertilization (CK1), biogas…

Mathematics, Vol. 13, Pages 958: Exploring the Role of Material Science in Advancing Quantum Machine Learning: A Scientometric Study

https://www.mdpi.com/2227-7390/13/6/958

Published: March 14, 2025 00:00

Quantum Machine Learning (QML) opens up exciting possibilities for tackling problems that are incredibly complex and consume a lot of time. The drive to make QML a reality has sparked significant progress in material science, inspiring a growing number of…

Biology and Life Sciences Forum, Vol. 38, Pages 11: Statement of Peer Review

https://www.mdpi.com/2673-9976/38/1/11

Published: March 14, 2025 00:00

In submitting conference proceedings to Biology and Life Sciences Forum, the volume editors of the proceedings certify to the publisher that all papers published in this volume have been subjected to peer review administered by the volume editors [...]

Microorganisms, Vol. 13, Pages 656: Biocontrol Potential of Bacillus velezensis RS65 Against Phytophthora infestans: A Sustainable Strategy for Managing Tomato Late Blight

https://www.mdpi.com/2076-2607/13/3/656

Published: March 14, 2025 00:00

This study aimed to investigate the biocontrol activity of rhizosphere isolates against late blight disease of tomatoes caused by the fungus Phytophthora infestans. A total of 30 rhizospheric bacterial isolates were evaluated for their antagonistic…

IJMS, Vol. 26, Pages 2608: Low Plasma Carnosinase-1 Activity in Patients with Left Ventricular Systolic Dysfunction: Implications for Carnosine Therapy in Heart Failure

https://www.mdpi.com/1422-0067/26/6/2608

Published: March 14, 2025 00:00

Therapeutic efficacy of histidyl dipeptides such as carnosine is hampered by circulating carnosinase-1 (CN1), which catalyzes carnosine’s hydrolysis and degradation. Prior reports suggest that oral carnosine may improve cardiometabolic parameters in…

Microorganisms, Vol. 13, Pages 657: Nitrogen Fertilization Alleviates Microplastic Effects on Soil Protist Communities and Rape (Brassica napus L.) Growth

https://www.mdpi.com/2076-2607/13/3/657

Published: March 14, 2025 00:00

Agricultural plastic mulch enhances crop yields but leads to persistent microplastic contamination in soils. Concurrently, nitrogen (N) fertilization and atmospheric deposition profoundly reshape microbial ecosystems. This study examined the individual and…

Applied Sciences, Vol. 15, Pages 3152: A Study of Immunoenzymatic Parameters in Pediatric Ischemic Stroke as a Contribution to More Efficient Pediatric Monitoring and Diagnosis

https://www.mdpi.com/2076-3417/15/6/3152

Published: March 14, 2025 00:00

Introduction: Pediatric ischemic stroke (IS) is a rare but severe neurological emergency, with an incidence of 2–13 per 100,000. Most cases occur in the prenatal period or early infancy. Integrating artificial intelligence (AI) into clinical practice…

JCM, Vol. 14, Pages 1959: The Unseen Burden: A Qualitative Investigation of Polish LGBTQ+ Caregivers’ Experiences

https://www.mdpi.com/2077-0383/14/6/1959

Published: March 14, 2025 00:00

Background/Objectives: As the world’s population ages, the growing number of individuals affected by Alzheimer’s disease and related dementias (ADRDs) will undoubtedly continue to impose social and economic challenges. Informal caregivers play…

Sensors, Vol. 25, Pages 1796: Factors Influencing Resistivity Inversion for CO2 Geological Storage Zones: A Quantitative Study

https://www.mdpi.com/1424-8220/25/6/1796

Published: March 14, 2025 00:00

This study establishes a homogeneous half-space and a horizontally layered two-layer background stratigraphy model using cross-borehole electrical resistivity tomography (ERT) based on an incomplete Gauss–Newton (IGN) method to investigate the…

Applied Sciences, Vol. 15, Pages 3102: Integrate the Isogeometric Analysis Approach Based on the T-Splines Function for the Numerical Study of a Liquefied Petroleum Gas (LPG) Cylinder Subjected to a Static Load

https://www.mdpi.com/2076-3417/15/6/3102

Published: March 13, 2025 00:00

LGP cylinders are necessary for fuel storage and home heating. To avoid material and human risk, it is essential to maintain their structural integrity. Extensive mechanical research studies and physical tests are necessary for its design. This paper…

Agronomy, Vol. 15, Pages 686: New Insights into the Regulatory Non-Coding RNAs Mediating Rice–Brown Planthopper Interactions

https://www.mdpi.com/2073-4395/15/3/686

Published: March 13, 2025 00:00

The brown planthopper (Nilaparvata lugens Stål, BPH) is a destructive pest of rice. Non-coding RNAs (ncRNAs) regulate the defense mechanisms in rice and the adaptive strategies of BPHs. In rice, ncRNAs modulate key resistance pathways such as…

Healthcare, Vol. 13, Pages 618: The Economic and Occupational Impact of Mental Health-Related Temporary Work Disabilities in Spanish Workers During and After the COVID-19 Pandemic: A Longitudinal Study

https://www.mdpi.com/2227-9032/13/6/618

Published: March 13, 2025 00:00

Background: The COVID-19 pandemic has affected mental health worldwide, exposing gaps in managing work-related disabilities. In Spain, Mutual Collaborators with Social Security play a pivotal role in managing temporary work disabilities associated with…

Energies, Vol. 18, Pages 1411: Research on Multi-Objective Programming Model of Profits and Carbon Emission Reduction in Manufacturing Industry

https://www.mdpi.com/1996-1073/18/6/1411

Published: March 13, 2025 00:00

As the issue of global climate change becomes increasingly severe, governments worldwide have implemented carbon reduction policies, such as carbon taxes and industrial low-carbon transitions, to effectively control total carbon emissions. This study…

J. Intell., Vol. 13, Pages 37: Critical Thinking and Teacher Training in Secondary Education

https://www.mdpi.com/2079-3200/13/3/37

Published: March 13, 2025 00:00

Various studies on the formation of critical thinking in teachers express difficulties in the training of teachers at different levels of education. Some of them recognize conceptual dispersion evidenced in their conceptions and explanations; others…

Water, Vol. 17, Pages 823: From Data Scarcity to Solutions: Hydrological and Water Management Modeling in a Highly Managed River Basin

https://www.mdpi.com/2073-4441/17/6/823

Published: March 13, 2025 00:00

In many river basins worldwide, decision-making depends on limited data and information. Yet, decisions, like the planning of a new multi-purpose dam, must be taken relying on available data. The incorporation of socio-economic developments, climate or…

Future, Vol. 3, Pages 4: Time to Focus on Movement and Active Play Across the First 2000 Days of Life

https://www.mdpi.com/2813-2882/3/1/4

Published: March 13, 2025 00:00

Chronic health conditions including obesity, cardiovascular diseases, type 2 diabetes, and depression are rising in Australia, and are often addressed reactively in adulthood rather than proactively during childhood. Evidence highlights the first 2000 days…

Applied Sciences, Vol. 15, Pages 3103: Key Barriers to Personalized Learning in Times of Artificial Intelligence: A Literature Review

https://www.mdpi.com/2076-3417/15/6/3103

Published: March 13, 2025 00:00

Personalized learning (PL) has emerged as a promising approach to address diverse educational needs, with artificial intelligence (AI) playing an increasingly pivotal role in its implementation. This systematic literature review examines the landscape of…

IJERPH, Vol. 22, Pages 418: Modeling the Interactions Between Chemicals and Proteins to Predict the Health Consequences of Air Pollution

https://www.mdpi.com/1660-4601/22/3/418

Published: March 13, 2025 00:00

The impacts of air pollution on human health have become a major concern, especially with rising greenhouse gas emissions and urban development. This study investigates the molecular mechanisms using the STITCH 4.0 and STRING 9.0 databases to analyze the…

Photonics, Vol. 12, Pages 255: Weyl Semimetal-Based Terahertz Chips for the Determination of Nickel Metal Particle Concentration in Sewage

https://www.mdpi.com/2304-6732/12/3/255

Published: March 13, 2025 00:00

A novel terahertz-responsive chip was developed for rapid, non-contact detection of nickel metal particle concentrations in aqueous solutions. The chip integrates a Weyl semimetal thin film as the active layer and a sub-wavelength metallic structure as the…

Healthcare, Vol. 13, Pages 619: Effects of Trehalose on Halitosis: A Randomized Cross-Over Clinical Trial

https://www.mdpi.com/2227-9032/13/6/619

Published: March 13, 2025 00:00

Background/Objectives: Halitosis is a condition characterized by an unpleasant malodor. Intra-oral halitosis is caused by volatile sulfur compounds (VSCs) and can be associated with oral dryness. Trehalose is one of the materials used to relieve oral…

Fermentation, Vol. 11, Pages 140: Novel Malolactic Fermentation Starter Formulated Using Native Lactic Acid Bacteria Strains from a Re-Emerging Wine-Growing Region of Argentina—A Pilot Scale Vinification

https://www.mdpi.com/2311-5637/11/3/140

Published: March 13, 2025 00:00

Argentina ranks worldwide among the top ten wine producers, known for its diverse terroirs and Malbec as its emblematic varietal. Typically, the winemaking process involves alcoholic fermentation, led by yeasts, and malolactic fermentation (MLF), primarily…

AI, Vol. 6, Pages 56: Emotion-Aware Embedding Fusion in Large Language Models (Flan-T5, Llama 2, DeepSeek-R1, and ChatGPT 4) for Intelligent Response Generation

https://www.mdpi.com/2673-2688/6/3/56

Published: March 13, 2025 00:00

Empathetic and coherent responses are critical in automated chatbot-facilitated psychotherapy. This study addresses the challenge of enhancing the emotional and contextual understanding of large language models (LLMs) in psychiatric applications. We…

Forests, Vol. 16, Pages 506: Assessing Ash (Fraxinus excelsior L.) Dieback Dynamics in the Białowieża Forest, Poland, Using Bi-Temporal High-Resolution Remote Sensing Data

https://www.mdpi.com/1999-4907/16/3/506

Published: March 13, 2025 00:00

The ash dieback epidemic, caused by the fungus Hymenoscyphus fraxineus, has been a significant issue in Europe for over 20 years, severely affecting ash tree populations (Fraxinus excelsior L.). In the Białowieża Forest, ash trees now represent…

Risks, Vol. 13, Pages 52: An Integrated Risk Management Methodology for Deposits and Loans

https://www.mdpi.com/2227-9091/13/3/52

Published: March 13, 2025 00:00

This paper presents an integrated risk management methodology for measuring and managing the economics, risks, and financial resources/constraints related to deposits and loans in a commercial bank. Within a comprehensive and integrated framework, we…

Energies, Vol. 18, Pages 1412: Investigation on Energy Enhancement of Shale Oil Imbibition Under Different Fracture Fluid Injection Methods—A Case Investigation of Jimsar Lucaogou Formation

https://www.mdpi.com/1996-1073/18/6/1412

Published: March 13, 2025 00:00

This paper describes an innovatively designed experimental method for fracturing fluid energy storage to explore the energy storage mechanism during the well shut-in process of fractured shale reservoirs. By improving the existing core clamp and adding…

Cells, Vol. 14, Pages 423: Stabilization of Transcription Factor, HIF-1α by Prolylhydroxylase 1 Knockout Reduces Cardiac Injury After Myocardial Infarction in Mice

https://www.mdpi.com/2073-4409/14/6/423

Published: March 13, 2025 00:00

Inhibition of HIF-prolyl hydroxylases (PHD1, PHD2, and PHD3) causes the stabilization of hypoxia-inducible factor-1α and -2α (HIF-1α and HIF-2α) to regulate various cell signaling pathways. Hypoxia-inducible factor (HIF) is crucial…

Computation, Vol. 13, Pages 72: Short-Term Predictions of Global Horizontal Irradiance Using Recurrent Neural Networks, Support Vector Regression, Gradient Boosting Random Forest and Advanced Stacking Ensemble Approaches

https://www.mdpi.com/2079-3197/13/3/72

Published: March 13, 2025 00:00

In today’s world, where sustainable energy is essential for the planet’s survival, accurate solar energy forecasting is crucial. This study focused on predicting short-term Global Horizontal Irradiance (GHI) using minute-averaged data from the…

Dentistry Journal, Vol. 13, Pages 124: Identifying Key Factors in Papilla Growth Around Implants: Focus on Intraoral Negative Pressure

https://www.mdpi.com/2304-6767/13/3/124

Published: March 13, 2025 00:00

The absence of interdental papillae in dental prosthetics often leads to unsatisfactory esthetic outcomes, such as black triangles and elongated clinical crowns. While previous research has demonstrated that papillae can regenerate in a coronal direction,…

Future Internet, Vol. 17, Pages 127: Deep Neural Network-Based Modeling of Multimodal Human–Computer Interaction in Aircraft Cockpits

https://www.mdpi.com/1999-5903/17/3/127

Published: March 13, 2025 00:00

Improving the performance of human–computer interaction systems is an essential indicator of aircraft intelligence. To address the limitations of single-modal interaction methods, a multimodal interaction model based on gaze and EEG target selection…

Cancers, Vol. 17, Pages 966: Deep Learning Models Based on Pretreatment MRI and Clinicopathological Data to Predict Responses to Neoadjuvant Systemic Therapy in Triple-Negative Breast Cancer

https://www.mdpi.com/2072-6694/17/6/966

Published: March 13, 2025 00:00

Purpose: To develop deep learning models for predicting the pathologic complete response (pCR) to neoadjuvant systemic therapy (NAST) in patients with triple-negative breast cancer (TNBC) based on pretreatment multiparametric breast MRI and…

Information, Vol. 16, Pages 220: An RFID-Based Indoor Guiding System for Visually Impaired People

https://www.mdpi.com/2078-2489/16/3/220

Published: March 13, 2025 00:00

This paper proposes a solution for guiding visually impaired people to reach predefined locations marked with preregistered passive ultra-high-frequency RFID tags inside public buildings (e.g., secretary’s offices and information desks). Our approach…

JoF, Vol. 11, Pages 219: Optimization of Protoplast Preparation and Establishment of PEG-Mediated Genetic Transformation Method in Cordyceps cicadae

https://www.mdpi.com/2309-608X/11/3/219

Published: March 13, 2025 00:00

Cordyceps cicadae (C. cicadae) is an important edible medicinal fungus; however, owing to its wild growth and lack of genome annotation, construction of a stable genetic transformation system in C. cicadae is greatly limited, impeding the extensive…

Metals, Vol. 15, Pages 310: Achieving High Strength and Plasticity by Controlling the Volume Fractions of Martensite and Ferrite in Rare Earth, Micro-Alloyed Dual-Phase Steel

https://www.mdpi.com/2075-4701/15/3/310

Published: March 13, 2025 00:00

The volume fractions of martensite and ferrite in dual-phase steel affect its strength and plasticity. In this study, the effect of heat treatment on the structure morphology and volume fractions of martensitic and ferrite was studied in rare earth,…

Diversity, Vol. 17, Pages 204: Understanding the Diversity and Distribution of Lycophytes and Ferns in Northeast China Based on Historical Records

https://www.mdpi.com/1424-2818/17/3/204

Published: March 13, 2025 00:00

Understanding the species diversity distribution of lycophytes and ferns is crucial for identifying biodiversity hotspots and conservation planning. Northeast China, a biodiversity-sensitive area affected by climate change, lacks comprehensive information…

Symmetry, Vol. 17, Pages 428: Hamming and Symbol-Pair Distances of Constacyclic Codes of Length 2ps over Fpm[u,v]⟨u2,v2,uv−vu⟩

https://www.mdpi.com/2073-8994/17/3/428

Published: March 13, 2025 00:00

Let R=Fpm[u,v]⟨u2,v2,uv−vu⟩, where p is an odd prime and m is a positive integer. For a unit α in R, α-constacyclic codes of length 2ps over R are ideals of R[x]⟨x2ps−α⟩, where s is a positive…

Biosensors, Vol. 15, Pages 180: Attention Affecting Response Inhibition in Overweight Adults with Food Addiction

https://www.mdpi.com/2079-6374/15/3/180

Published: March 13, 2025 00:00

Food addiction is associated with attention bias and response inhibition deficits, while the relationship between these two domains is unclear. Participants with body mass index (BMI) ≥ 25 and exhibiting food addiction behaviors (FA group, n = 20) were…

Animals, Vol. 15, Pages 813: Effect of Inhibin Immunization on Reproductive Hormones and Testicular Morphology of Dezhou Donkeys During the Non-Breeding Season

https://www.mdpi.com/2076-2615/15/6/813

Published: March 13, 2025 00:00

The present study was designed to investigate the potential role of inhibin immunization on plasma hormone concentration and testicular histoarchitecture of Dezhou donkeys in the nonbreeding season (November–February). For this purpose, adult Dezhou…

Oral, Vol. 5, Pages 19: Comparative Analysis of Gene Expression in Periodontal Ligament Stem Cells Exposed to Biodentine and Bio-C Repair: Implications for Cementogenesis—An In Vitro Study

https://www.mdpi.com/2673-6373/5/1/19

Published: March 13, 2025 00:00

Background/Objectives: Bioactive materials are gaining increased popularity as materials of choice for pulpal regeneration. A similar trend is emerging with root repair materials; however, there is a significant gap in the literature about cementogenic…

Plants, Vol. 14, Pages 894: Hypoglycemic and Hypolipidemic Effects of Triterpenoid Standardized Extract of Agave durangensis Gentry

https://www.mdpi.com/2223-7747/14/6/894

Published: March 13, 2025 00:00

Diabetes mellitus is a chronic, degenerative, and multifactorial disease characterized by hyperglycemia, and at least 537 million people suffered from diabetes in 2021. Agave durangensis Gentry, a species of agave native to the state of Durango, reports…

CIMB, Vol. 47, Pages 187: Detection of Helicobacter pylori and the Genotypes of Resistance to Clarithromycin, Fluoroquinolones, and Metronidazole in Gastric Biopsies: An In Silico Analysis to Help Understand Antibiotic Resistance

https://www.mdpi.com/1467-3045/47/3/187

Published: March 13, 2025 00:00

Antibiotic resistance in Helicobacter pylori is increasing rapidly and emerging as a major factor in treatment failure. We aimed to identify genetic mutations associated with resistance to clarithromycin (23S rRNA peptidyl transferase), fluoroquinolones…

Geriatrics, Vol. 10, Pages 39: Cognitive Performance Among Older Adults with Subjective Cognitive Decline

https://www.mdpi.com/2308-3417/10/2/39

Published: March 13, 2025 00:00

Objectives: The main objective of this cross-sectional study was to investigate if there are significant differences in cognition between a group of older adults with subjective cognitive decline (SCD) and cognitively intact controls. Methods: An initial…

Chemosensors, Vol. 13, Pages 103: Method Validation and Determination of Ametryn Pesticide in Water Samples by QuEChERS-GC-MS

https://www.mdpi.com/2227-9040/13/3/103

Published: March 13, 2025 00:00

This study developed an analytical method to monitor pesticide residues in water, ensuring compliance with maximum limits and protecting human health. While the QuEChERS method is commonly used for food matrices, its application to aqueous samples has been…

IJMS, Vol. 26, Pages 2565: Isolation, Identification, and Genetic Evolution Analysis of VP1 Gene of Feline Calicivirus Strain ZZ202306

https://www.mdpi.com/1422-0067/26/6/2565

Published: March 13, 2025 00:00

This study investigated a suspected Feline calicivirus (FCV) outbreak at a veterinary facility in Zhengzhou, Henan Province, China. RT-PCR analysis confirmed the FCV presence, with subsequent CRFK cell culture propagation leading to the isolation and…

Sensors, Vol. 25, Pages 1774: Aptamer-Functionalized Platform for Selective Bacterial Isolation and Rapid RNA Purification Using Capture Pins

https://www.mdpi.com/1424-8220/25/6/1774

Published: March 13, 2025 00:00

Efficient bacterial lysis and RNA purification are essential for molecular diagnostics and biosensing applications. This study presents a piezoelectric platform integrated with gold-plated RNA capture pins (RCPs) functionalized with synthetic…

Metabolites, Vol. 15, Pages 198: The Therapeutic Potential of Orange Juice in Cardiac Remodeling: A Metabolomics Approach

https://www.mdpi.com/2218-1989/15/3/198

Published: March 13, 2025 00:00

Cardiovascular diseases are a leading cause of death worldwide, and the process of cardiac remodeling lies at the core of most of these diseases. Sustained cardiac remodeling almost unavoidably ends in progressive muscle dysfunction, heart failure, and…

Religions, Vol. 16, Pages 359: Empirical Evaluation of the Role of African Traditional Religion in Promoting Gender-Based Violence in Southeast Nigeria

https://www.mdpi.com/2077-1444/16/3/359

Published: March 13, 2025 00:00

The tenets and philosophies of the Igbo traditional religion (ATR) form the bedrock of the Igbo traditional and sociocultural belief system whose principles and practices directly and indirectly influence the perceptions and way of life of the Igbo…

Molecules, Vol. 30, Pages 1281: Study on the Ultrasonic-Assisted Extraction Process of Anthocyanin from Purple Cabbage with Deep Eutectic Solvent

https://www.mdpi.com/1420-3049/30/6/1281

Published: March 13, 2025 00:00

In this paper, purple cabbage was used as raw material for ultrasonic-assisted extraction of anthocyanin with deep eutectic solvent. The effects of extraction solvent type, solid–liquid ratio, moisture, extraction temperature, and time on the yield…

Religions, Vol. 16, Pages 360: Why Ethics Requires a God and Is Safer from Evolutionary Debunking Threats as a Result: A Reply to Sterba

https://www.mdpi.com/2077-1444/16/3/360

Published: March 13, 2025 00:00

Sterba has argued that ethics does not require God and that an atheistic objectivist ethics is compatible with an evolutionary account of our development. This paper argues that though ethics does not require God specifically, it does require a god of some…

Energies, Vol. 18, Pages 1410: Enhancing Grid Stability in Renewable Energy Systems Through Synchronous Condensers: A Case Study on Dedieselization and Assessment Criteria Development

https://www.mdpi.com/1996-1073/18/6/1410

Published: March 13, 2025 00:00

The dedieselization program is one of the PLN’s (Indonesia’s state-owned utility company) programs to reduce the greenhouse gas effect. The program manifestation is the integration of photovoltaic (PV) systems into isolated island networks by…

Applied Microbiology, Vol. 5, Pages 29: Transplantation of Fecal Flora from Patients with Atherosclerosis to Mice Can Increase Serum Low-Density Lipoprotein Cholesterol and Affect Intestinal Flora and Its Metabolites

https://www.mdpi.com/2673-8007/5/1/29

Published: March 13, 2025 00:00

Atherosclerosis (AS) is emerging as a major global public health problem. Researchers are developing and implementing various anti-AS strategies. This study aimed to investigate gut microbiota and metabolite changes associated with elevated serum…

Marine Drugs, Vol. 23, Pages 124: Multi-Functional Alginate Lyase AlgVR7 from Vibrio rumoiensis: Structural Insights and Catalytic Mechanisms

https://www.mdpi.com/1660-3397/23/3/124

Published: March 13, 2025 00:00

In this study, we identified AlgVR7, a novel bifunctional alginate lyase from Vibrio rumoiensis and characterized its biochemical properties and substrate specificity. Sequence alignment analysis inferred the key residues K267, H162, N86, E189, and T244…

Information, Vol. 16, Pages 219: Blockchain-Based Privacy-Preserving Authentication and Access Control Model for E-Health Users

https://www.mdpi.com/2078-2489/16/3/219

Published: March 13, 2025 00:00

The advancement of e-health systems has resulted in substantial enhancements in healthcare delivery via effective data management and accessibility. The use of digital health solutions presents dangers to sensitive health information, including…

Microorganisms, Vol. 13, Pages 641: Safety and Efficacy of Ephedrine Alkaloids-Free Ephedra Herb Extract (EFE) for Mild COVID-19: A Double-Blind, Placebo-Controlled, Randomized Comparative Trial

https://www.mdpi.com/2076-2607/13/3/641

Published: March 12, 2025 00:00

Several Ephedra Herb-containing Kampo medicines are common initial treatments for various infections; however, the ephedrine alkaloids in Ephedra Herb can cause side effects by stimulating adrenergic receptors. Accordingly, an ephedrine alkaloids-free…