@www.fightaging.org@rss-parrot.net
I'm an automated parrot! I relay a website's RSS feed to the Fediverse. Every time a new post appears in the feed, I toot about it. Follow me to get all new posts in your Mastodon timeline! Brought to you by the RSS Parrot.
---
The science of rejuvenation biotechnology. Advocacy for longer, healthier lives.
Site URL: www.fightaging.org
Feed URL: www.fightaging.org/feed
Posts: 16
Followers: 1
Autophagy Upregulation in Bone Marrow Stromal Cells Extends Life in Mice
Published: September 6, 2024 18:55
Autophagy is the name given to the collection of processes that recycle damaged and excess proteins and structures in the cell. It encompasses mechanisms by which these recycling targets are first identified, then flagged, and finally transported to a…
Hormone Replacement Therapy Produces Only a Modest Improvement in Phenotypic Age
Published: September 6, 2024 10:22
Phenotypic age is a popular measure of biological age, in part because it is easily calculated using a few commonly available assays conducted on a blood sample. One of the interesting items in this study is the fact that average phenotypic age is somewhat…
S6K1 Inhibition Reduces Liver Inflammation, a Possible Mechanism Mediating Slowed Aging
Published: September 6, 2024 10:11
Reduced expression of SK61 is one downstream consequence of mTOR inhibition, a class of intervention that is demonstrated to slow aging in animal models. Researchers here down that SK61 inhibition reduces liver inflammation, in part by reducing the burden…
Arguing for More Practical Research Based on a Hyperfunction View of Aging
Published: September 5, 2024 18:22
Hyperfunction theories of aging have emerged in recent years from the programmed aging camp, vary considerably, and have yet to settle down into a single consensus hyperfunction theory. Roughly speaking, in this viewpoint aging is the consequence of the…
A Focus on the Importance of Synaptic Plasticity in Age-Related Neurodegeneration
Published: September 5, 2024 10:22
The brain continually adjusts the networks of synaptic connections between neurons, and cognitive functions such as memory and learning absolutely require this ongoing plasticity of neural networks. With aging synaptic plasticity declines, and this loss of…
Analyzing the Progression of Alzheimer's Disease
https://www.fightaging.org/archives/2024/09/analyzing-the-progression-of-alzheimers-disease/
Published: September 5, 2024 10:11
A better understanding of how exactly Alzheimer's disease progresses may open the door to more effective early intervention aimed at preventing the condition from occurring. The study noted here adds to the evidence for inflammatory dysfunction of…
What Have We Learned from Heterochronic Parabiosis?
https://www.fightaging.org/archives/2024/09/what-have-we-learned-from-heterochronic-parabiosis/
Published: September 4, 2024 17:05
In heterochronic parabiosis, the circulatory systems of an old mouse and young mouse are surgically joined. It is now well established that this accelerates measures of aging in the young mouse, and reverses measures of aging in the old mouse. This…
Autophagy of the Endoplasmic Reticulum Appears Important in Life Span
Published: September 4, 2024 10:22
The endoplasmic reticulum is a cell structure associated with ribosomes that aids in protein folding and protein transport, but also has a range of other purposes. It is an important component of the machinery that builds proteins and other molecules in…
A Genetic View of the Degree to Which Human Longevity is Shaped by Cancer
Published: September 4, 2024 10:11
Cancers are not as high in the list of major causes of death in our species as one might imagine. In this we differ from laboratory mice, which researchers have fondly referred to as "little cancer factories". Nonetheless, when thinking about the evolution…
Thoughts on Combination Therapies to Treat Aging
https://www.fightaging.org/archives/2024/09/thoughts-on-combination-therapies-to-treat-aging/
Published: September 3, 2024 17:10
The research and development communities are not good at prioritizing the evaluation and development of combination therapies. The incentives surrounding intellectual property and demands of regulators can explain much of this, and the rest is due to the…
More Evidence for the Importance of Senescent Cell / Immune Cell Interactions in Proficient Regeneration
Published: September 3, 2024 10:22
Studies of the biochemistry of wound healing in species capable of complete regeneration of limbs and organs, such as salamanders and zebrafish, has pointed to differences in the behavior of senescent cells and immune cells such as macrophages during the…
Aging Changes the Heart's Response to Injury
https://www.fightaging.org/archives/2024/09/aging-changes-the-hearts-response-to-injury/
Published: September 3, 2024 10:11
Older people are less capable of regeneration from injury. On top of that, the heart is one of the least regenerative organs in the body, vulnerable in ways that other muscle tissue is not. Cardiovascular disease leads to heart injury, and the aged body is…
A Continued Focus on Autophagy in Clinical Development
https://www.fightaging.org/archives/2024/09/a-continued-focus-on-autophagy-in-clinical-development/
Published: September 2, 2024 17:53
Evidence suggests that improved autophagy is the most important mechanism by which calorie restriction and other mild stresses produce slowed aging and extended life in lower animals and mammals. Disabling autophagy prevents calorie restriction from…
Expression of Contractile Proteins in the Heart Changes with Age
Published: September 2, 2024 10:22
Contractile proteins embedded into the cell cytoskeleton enable muscle cells to change shape in response to stimulus from the nervous system. Here researchers explore age-related changes in these proteins in the heart, finding that the balance of what are…
Towards a Better Understanding of CD4+ T Cells in Immune Aging
Published: September 2, 2024 10:11
The immune system is enormously complex, and one can subdivide its cell populations near endlessly via many different combinations of characteristics, most commonly the type and amount of cell surface markers. Immune cell populations change in number and…
Fight Aging! Newsletter, September 2nd 2024
https://www.fightaging.org/archives/2024/09/fight-aging-newsletter-september-2nd-2024/
Published: September 1, 2024 10:09
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested…