🦜 ((Triple Negative Breast Neoplasmspathology[MAJR]))
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((Triple Negative Breast Neoplasmspathology[MAJR])): Latest results from PubMed
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Myeloid Cell Targeting Strategies Show Limited Durable Activity in the Breast Cancer Tumor Microenvironment and Do Not Enhance the Activity of Thermally Ablative Focused Ultrasound
https://pubmed.ncbi.nlm.nih.gov/42274627/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1zA4h3Qg-ND_Lvx8qFap6dOGSjORqFX5gx1cFZpJGVFLXsasr2&fc=None&ff=20260611192300&v=2.20.0
Published: June 11, 2026 10:00
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BrCa), owing to its lack of targetable receptors and resistance to chemical and molecularly targeted therapeutic approaches. While chemotherapy and surgical resection…
Annexin A6 Modulates the Secretion of Pro-Inflammatory Cytokines and Exosomes via Interaction with SNAP23 in Triple-Negative Breast Cancer Cells
https://pubmed.ncbi.nlm.nih.gov/42274606/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1zA4h3Qg-ND_Lvx8qFap6dOGSjORqFX5gx1cFZpJGVFLXsasr2&fc=None&ff=20260611192300&v=2.20.0
Published: June 11, 2026 10:00
Annexin A6 (AnxA6) is a predominantly intracellular calcium-dependent membrane-binding multifunctional protein that is also detected extracellularly and in small extracellular vesicles (exosomes). We previously demonstrated that lapatinib resistance in…
Stage at Diagnosis and Molecular Subtype Distribution of Breast Cancer in Sub-Saharan Africa: A Systematic Review
https://pubmed.ncbi.nlm.nih.gov/42266142/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1zA4h3Qg-ND_Lvx8qFap6dOGSjORqFX5gx1cFZpJGVFLXsasr2&fc=None&ff=20260611073704&v=2.20.0
Published: June 10, 2026 10:00
CONCLUSIONS: Our findings provide an updated synthesis of the stage at diagnosis of breast cancer in sub-Saharan Africa since January 2014. Although a high proportion of patients continue to present at late stage, comparisons with earlier reports should be…
Novel N9-Substituted 6-Cycloalkylaminoadenines as Promising Compounds Against Triple Negative Breast Cancer
https://pubmed.ncbi.nlm.nih.gov/42244243/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1zA4h3Qg-ND_Lvx8qFap6dOGSjORqFX5gx1cFZpJGVFLXsasr2&fc=None&ff=20260610072345&v=2.20.0
Published: June 5, 2026 10:00
Triple negative breast cancer (TNBC) accounts for 15% of breast cancers, exhibiting high proliferation and resistance to conventional treatments, highlighting the need for innovative therapies. Purine derivatives are recognised for their anticancer…
Impact of Germline BRCA1/2 Mutations on Clinical Outcomes in Metastatic Triple-Negative Breast Cancer Patients Treated with Sacituzumab Govitecan-An International CEBCC Study from Poland, the Czech Republic and Slovakia
https://pubmed.ncbi.nlm.nih.gov/42238016/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1zA4h3Qg-ND_Lvx8qFap6dOGSjORqFX5gx1cFZpJGVFLXsasr2&fc=None&ff=20260608063257&v=2.20.0
Published: June 4, 2026 10:00
Background: Germline breast cancer susceptibility gene 1/2 (BRCA1/2) variants guide breast cancer treatment, but their clinical relevance in metastatic triple-negative breast cancer (mTNBC) treated with sacituzumab govitecan (SG) remains unclear. The study…
Modeling the role of urokinase-type plasminogen activator, uPA, and circulating cancer-associated fibroblasts (cCAFs) in breast cancer cell extravasation
https://pubmed.ncbi.nlm.nih.gov/42234219/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1zA4h3Qg-ND_Lvx8qFap6dOGSjORqFX5gx1cFZpJGVFLXsasr2&fc=None&ff=20260606021548&v=2.20.0
Published: June 3, 2026 10:00
Circulating Cancer-Associated Fibroblasts (cCAFs) have been identified in circulating tumor cell clusters from all stages of disease progression in breast cancer patients. We have shown that CAFs promote lung metastases in the mouse tail vein model when…
Dectin-1 signaling promotes Galectin-3 shedding and expansion of immunosuppressive CD71+ erythroid cells in breast cancer
https://pubmed.ncbi.nlm.nih.gov/42228003/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1zA4h3Qg-ND_Lvx8qFap6dOGSjORqFX5gx1cFZpJGVFLXsasr2&fc=None&ff=20260605012948&v=2.20.0
Published: June 2, 2026 10:00
Immunotherapy with immune checkpoint inhibitors (ICIs) has transformed cancer treatment, yet many patients fail to respond, underscoring the need to better understand mechanisms of resistance. One emerging mechanism involves the recruitment of erythroid…
Integrated Network Pharmacology and Machine Learning to Reveal the Mechanisms of Schisandrin A Against Triple-Negative Breast Cancer
https://pubmed.ncbi.nlm.nih.gov/42220063/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1zA4h3Qg-ND_Lvx8qFap6dOGSjORqFX5gx1cFZpJGVFLXsasr2&fc=None&ff=20260601095852&v=2.20.0
Published: June 1, 2026 10:00
This study aimed to elucidate the mechanism of action of Schisandrin A in the intervention of triple-negative breast cancer (TNBC). Through the application of network pharmacology and the integration of targets from multiple databases, the research…
Premedication with steroids in breast cancer - supportive treatment or tumour growth promotion?
https://pubmed.ncbi.nlm.nih.gov/42218678/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1zA4h3Qg-ND_Lvx8qFap6dOGSjORqFX5gx1cFZpJGVFLXsasr2&fc=None&ff=20260531144233&v=2.20.0
Published: May 31, 2026 10:00
Glucocorticoids, most commonly dexamethasone, are widely used alongside breast cancer therapy to alleviate adverse effects of chemotherapy, particularly allergic reactions and nausea. However, growing evidence shows that the activation of the…