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Biological Science Disciplineshistory[MAJR]: Latest results from PubMed
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Professor Stanisław Jan Konturek: imagination and knowledge - without them, there can be no true doctor
Published: December 2, 2025 11:00
Physiology, as a science, is the foundation of modern medical knowledge and the starting point for understanding the mechanisms of most diseases. The dynamic development of physiology at the Jagiellonian University dates back to the 14th century, but the…
Measurement under uncertainty: theory-measurement relations in early electrophysiological research
Published: December 1, 2025 11:00
Recent work in philosophy of measurement has converged on a "theory-dependence consensus", according to which measurement reliability requires sophisticated theoretical scaffolding. This consensus has been largely shaped by case studies from physics and…
Bacteriological research and 'puerperal' fever: female health and childbirth in late colonial India
Published: November 30, 2025 11:00
This article explores female healthcare at the crossroads of bacteriology and obstetric research. Puerperal fever or childbed fever manifested as an epidemic since the nineteenth century, and in both Europe and America, it charted a distinct course for…
The people behind the papers - Rebecca Oramas and Jianjun Sun
Published: November 24, 2025 11:00
Drosophila insulin-like peptide 8 (ILP8) is expressed in mature follicle cells, but not in younger follicles. In their work, Jianjun Sun and colleagues show that ILP8 is required to induce ovulation and egg laying in virgin Drosophila females. To learn…
An education in tolerance: the 2025 Nobel Prize in Physiology or Medicine
Published: November 19, 2025 11:00
The 2025 Nobel Prize in Physiology or Medicine has been awarded to Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance". This award celebrates research into the mechanisms by which the adaptive…
The people behind the paper - Robert Morabito and Benjamin Martin
Published: November 17, 2025 11:00
Nervous system and mesodermal tissue development in vertebrate embryos rely on the formation of transient midline tissues - such as the floorplate, notochord and hypochord - by midline progenitor cells. In a comprehensive new study, Benjamin Martin and…
How Rudolph Virchow changed the approach to autopsy of the brain
Published: November 13, 2025 11:00
Anatomical studies of the brain and successive analyses of this organ were performed in ancient times. Indeed, notes found in the Edwin Smith Papyrus mention that the Egyptians identified the meninges and gyri millennia ago. Their successors examined the…
Hogness at one hundred
Published: November 12, 2025 11:00
During his remarkable scientific career, David S. Hogness transformed the molecular analysis of genes, genomes, and animal development. Hogness was born 1 century ago this month, on November 17, 1925. On the 100th anniversary of his birth, we would like to…
The people behind the papers - Hannah Schrader Dear, Nicole Franks and Benjamin Allen
Published: November 7, 2025 11:00
There has been a lack of experimental tools to visualise endogenous GLI proteins - the transcriptional effectors of the Hedgehog signalling pathway. In a new study, Allen and colleagues present a homozygous reporter mouse line in which each of the three…
Robert Haselkorn (1934-2025): Pioneer in molecular biology and microbiology
Published: November 5, 2025 11:00
Robert Haselkorn (1934-2025) began a long and impactful career during the early years of nucleic acids research when the foundations of molecular biology were being laid. Focusing first on plant viruses, and then also bacteriophage, he hit upon a…