RSS Parrot

Molecular glues evolve from serendipity to rational design

https://pubmed.ncbi.nlm.nih.gov/41344934/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251205071312&v=2.18.0.post22+67771e2

Published: December 4, 2025 11:00

Molecular glues (MGs) modulate protein interactions to inhibit, activate, or degrade targets. Classical MGs like thalidomide, cyclosporin, and fusicoccin were discovered serendipitously; a key challenge is to develop rational design approaches for MGs.…

The Impact of AI-Recommended Content Affordances on Post-Purchase Intention in Stockout Substitution Scenarios

https://pubmed.ncbi.nlm.nih.gov/41301309/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251127075745&v=2.18.0.post22+67771e2

Published: November 27, 2025 11:00

Stockouts significantly threaten consumer loyalty and cause substantial economic losses. In response, online platforms are widely deploying AI recommender systems to provide substitutes. However, whether such AI-driven substitution strategies can…

Chest Wound Gunshot Management Aided by Cardiopulmonary Bypass: Interdisciplinary Teamwork or "Serendipity"?

https://pubmed.ncbi.nlm.nih.gov/41283604/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251124141801&v=2.18.0.post22+67771e2

Published: November 24, 2025 11:00

Background and clinical significance. Penetrating cardiothoracic wounds require prompt treatment in order to decrease mortality and morbidity. Surgical therapy, aimed at bleeding control and removal of damaged tissue, varies widely from the direct suture…

Pushing your luck: on chance, serendipity, and athlete development

https://pubmed.ncbi.nlm.nih.gov/41269499/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251121173132&v=2.18.0.post22+67771e2

Published: November 21, 2025 11:00

The notion that problems with prediction can be resolved with more, and better, data has a long history. In this paper, we examine the role of chance and randomness (i.e., events where there is a low probability of occurrence) in athlete development,…

Serendipity How? Data Insights During the Age of Artificial Intelligence

https://pubmed.ncbi.nlm.nih.gov/41231389/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251113130254&v=2.18.0.post22+67771e2

Published: November 13, 2025 11:00

No abstract

Accelerating the discovery of multicatalytic cooperativity

https://pubmed.ncbi.nlm.nih.gov/41183569/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251104034524&v=2.18.0.post22+67771e2

Published: November 3, 2025 11:00

Cooperative catalysis, in which multiple catalytic units operate synergistically, underpins a variety of synthetically and mechanistically important organic reactions^(1-4). Despite its potential utility in new reactivity contexts, approaches to the…

Linker Enantiomericity Engineering in Reticular Frameworks for Architecting Robust Materials with Synergetic Open Metal Sites for Efficient SF6 Capture

https://pubmed.ncbi.nlm.nih.gov/41158087/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251029080206&v=2.18.0.post22+67771e2

Published: October 29, 2025 10:00

Chiral linkers offer built-in enantiomericity capable of regulating pore microenvironments or even net dimensions and topologies of the resulting reticular frameworks. Whereas it has been established that enantiopure and racemic linkers can form…

LorBin: efficient binning of long-read metagenomes by multiscale adaptive clustering and evaluation

https://pubmed.ncbi.nlm.nih.gov/41136439/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251025004700&v=2.18.0.post22+67771e2

Published: October 24, 2025 10:00

Long-read sequencing has transformed metagenomics and improved the quality of metagenome-assembled genomes (MAGs). However, current binning methods struggle with identifying unknown species and managing imbalanced species distributions. Here, we present…

From Serendipity to Systematics: Tracing the Trails of Cockroach Research in India

https://pubmed.ncbi.nlm.nih.gov/41119818/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251022141627&v=2.18.0.post22+67771e2

Published: October 21, 2025 10:00

Globally, the cockroach diversity comprises approximately 4641 nominative species, 188 of which are reported in India classified under 73 genera. However, it remains a poorly studied and overlooked groups in terms of species documentation, taxonomy and…

Serendipity discrete complexes with enhanced regularity

https://pubmed.ncbi.nlm.nih.gov/41114403/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20251022141627&v=2.18.0.post22+67771e2

Published: October 20, 2025 10:00

In this work we address the problem of finding serendipity versions of approximate de Rham complexes with enhanced regularity. The starting point is a new abstract construction of general scope which, given three complexes linked by extension and reduction…