RSS Parrot

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays

https://pubmed.ncbi.nlm.nih.gov/40077831/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250313083957&v=2.18.0.post9+e462414

Published: March 13, 2025 10:00

Uncompetitive inhibition is an effective strategy for suppressing dysregulated enzymes and their substrates, but discovery of suitable ligands depends on often-unavailable structural knowledge and serendipity. Hence, despite surging interest in mass…

Rational Design of Near-Infrared Reflective Pigments by Adjusting the Ni2+ Coordination Environment

https://pubmed.ncbi.nlm.nih.gov/40051261/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250307072603&v=2.18.0.post9+e462414

Published: March 7, 2025 11:00

Inorganic pigments offer excellent potential because of their resilience in a variety of environments, and high-reflectance near-infrared (NIR) pigments are a useful tactic to reduce the heat island effect. Nonetheless, the design of inorganic pigments is…

New perspectives on repetitive behaviour

https://pubmed.ncbi.nlm.nih.gov/40048024/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250306143652&v=2.18.0.post9+e462414

Published: March 6, 2025 11:00

Human existence is shaped by interconnected patterns and repetitions that unfold in rhythmic cycles, from biological functions to socially constructed behaviors. While innate (physiological) and natural (environmental) cycles remain fixed, self-constructed…

Immersive Data-Driven Storytelling: Scoping an Emerging Field Through the Lenses of Research, Journalism, and Games

https://pubmed.ncbi.nlm.nih.gov/40031146/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250304033848&v=2.18.0.post9+e462414

Published: March 3, 2025 11:00

In recent years, data-driven stories have found a firm footing in journalism, business, and education. They leverage visualization and storytelling to convey information to broader audiences. Likewise, immersive technologies, like augmented and virtual…

From Rat Tails to Glycoproteostasis: Motivated by Biology, Enabled by Biophysics, and Lucky

https://pubmed.ncbi.nlm.nih.gov/40024434/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250303015439&v=2.18.0.post9+e462414

Published: March 2, 2025 11:00

In this article I tell the story of my career path and how I have come to focus my research on protein folding in the cell. My early fascination with protein folding began during my undergraduate research. My graduate work exploited reductionist approaches…

From Serendipity to Scalability in Rare Disease Patient Collaborations

https://pubmed.ncbi.nlm.nih.gov/39958601/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250217133556&v=2.18.0.post9+e462414

Published: February 17, 2025 11:00

As the rate of diagnosis for rare disease increases, so does the need to develop scalable solutions to address patient community needs. Drawing upon our experiences in rare intellectual and developmental disability research, advocacy, and treatment, we…

Drug development in psychiatry: 50 years of failure and how to resuscitate it

https://pubmed.ncbi.nlm.nih.gov/39952266/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250215175057&v=2.18.0.post9+e462414

Published: February 14, 2025 11:00

The past 50 years have seen remarkable advances in the science of medicine. The pharmacological treatments of disorders such as hypertension, immune disorders, and cancer are fundamentally different from those used in the 1970s, and are now more often…

Serendipity Can Rule the Day: Remarkable Efficacy of a Mushroom Extract Powder in Childhood Treatment-Resistant Epilepsy

https://pubmed.ncbi.nlm.nih.gov/39951934/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250215175057&v=2.18.0.post9+e462414

Published: February 14, 2025 11:00

INTRODUCTION: The goal of this report is to highlight an unanticipated effect of medicinal mushroom supplement in reducing seizures in a child.

Thermally Induced Reversible Martensitic Phase Transition and Self-Healing in Nickel Glycinamide Crystals

https://pubmed.ncbi.nlm.nih.gov/39945668/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250213134815&v=2.18.0.post9+e462414

Published: February 13, 2025 11:00

Martensitic phase transitions and self-healing in molecular compounds are extremely rare, and while they carry potential for rapid energy transduction, they are currently found only by serendipity. Here, we report the observation of both phenomena in a…

Hormonology: A kaleidoscopic tale of dedication, serendipity, and ingenuity

https://pubmed.ncbi.nlm.nih.gov/39938725/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250213032525&v=2.18.0.post9+e462414

Published: February 12, 2025 11:00

This article delves into stories of hormone discovery, characterization, clinical application, and the scientists themselves. Our journey begins with Arnold Berthod's rooster castration experiments, laying the groundwork for understanding testosterone, and…

Can researchers attract serendipity?

https://pubmed.ncbi.nlm.nih.gov/39934027/?utm_source=RSS-Parrot-Bot&utm_medium=rss&utm_campaign=None&utm_content=1nwkqzEtY5u_6fo79woxBsnRZCJiA07pXIz5ZHOeh83WUBQkDf&fc=None&ff=20250212020355&v=2.18.0.post9+e462414

Published: February 11, 2025 11:00

No abstract