@pubmed.ncbi.nlm.nih.gov.rss-feed.feed.id.1naywjerihpnd1zezqkcjfjmscln1zmapf2zw7sxqst8hb9mzq.v.2.18.0.post9.e462414.ff.20241105133420.utm.source.rss-parrot-bot.utm.medium.rss.utm.content.1naywjerihpnd1zezqkcjfjmscln1zmapf2zw7sxqst8hb9mzq@rss-parrot.net
I'm an automated parrot! I relay a website's RSS feed to the Fediverse. Every time a new post appears in the feed, I toot about it. Follow me to get all new posts in your Mastodon timeline! Brought to you by the RSS Parrot.
---
Disease Ontology: Latest results from PubMed
Feed URL: pubmed.ncbi.nlm.nih.gov/rss/search/1naYwjERihpnD1ZeZQKCjFJMSCln1ZmAPF2zw7SxQst8hb9Mzq/
Posts: 10
Followers: 1
Analysis of hub genes temporal dynamics in cardiac ischemia/reperfusion injury: a bioinformatics and experimental study
Published: December 5, 2025 11:00
CONCLUSION: Analysis across multiple datasets and HL-1 cell experimental models revealed four significantly altered genes-Serpine1, Ccl2, Il6 and Fn1-indicating their potential targets for MIRI.
The DO-KB knowledgebase 2026 update: expanding programmatic and language access
Published: November 26, 2025 11:00
The Human Disease Ontology Knowledgebase (DO-KB; https://disease-ontology.org/), a Global Core Biodata Resource, serves as a reference framework for multiscale biomedical data integration and analysis, within a unifying etiology-based disease…
RBP2GO 2.0: Integrating disease associations and sequence features to explore RNA-binding protein functions
Published: November 24, 2025 11:00
RNA-binding proteins (RBPs) play key roles in a wide range of biological processes and human diseases. Here, we updated RBP2GO, a comprehensive resource on RBPs, their binding partners, and functions across 13 species. The database RBP2GO 2.0 now provides…
Machine learning-driven exploration of therapeutic targets for atrial fibrillation-joint analysis of single-cell and bulk transcriptomes and experimental validation
Published: November 19, 2025 11:00
CONCLUSION: This study provides new insights into the molecular mechanisms of AF and offers potential non-invasive biomarkers for AF diagnosis. The identified key genes and constructed model may facilitate the development of targeted therapies for AF.
Consistent performance of large language models in rare disease diagnosis across ten languages and 4917 cases
Published: October 15, 2025 10:00
BACKGROUND: Large language models (LLMs) are increasingly used medicine for diverse applications including differential diagnostic support. The training data used to create LLMs such as the Generative Pretrained Transformer (GPT) predominantly consist of…
Bee venom promotes exosome secretion and alters miRNA cargo in T cells
Published: October 13, 2025 10:00
Exosomes are important mediators of intercellular communication, primarily through the transfer of miRNAs. However, the mechanisms regulating exosome secretion and miRNA cargo loading in T cells remain incompletely understood. In this study, we…
Mondo: Integrating Disease Terminology Across Communities
Published: October 6, 2025 10:00
Precision medicine aims to enhance diagnosis, treatment, and prognosis by integrating multimodal data at the point of care. However, challenges arise due to the vast number of diseases, differing methods of classification, and conflicting terminological…
Comprehensive identification of immune-related biomarkers and therapeutic targets in preeclampsia: integrative bioinformatics and experimental validation
Published: October 3, 2025 10:00
CONCLUSIONS: Our study identified four hub IRDEGs that may serve as potential diagnostic indicators and therapeutic targets for PE. These findings suggest an important role of immune dysregulation in PE pathogenesis and offer new perspectives for treatment…
Emerging plasticizer induced lipid metabolism disorders revealed by network toxicology molecular docking and dynamics simulation
Published: October 3, 2025 10:00
Acetyl tributyl citrate (ATBC) and epoxidized soybean oil (ESBO) are widely used emerging plasticizers, but their potential to induce lipid metabolism disorders remains poorly understood. In this study, we explored their toxicological mechanisms using a…
Exploring CCND1 as a Key Target of Acorus calamus Against RSV Infection: Network Pharmacology, Molecular Docking, and Bioinformatics Analysis
Published: September 29, 2025 10:00
Acorus calamus, a traditional Tibetan medicine with potential antiviral activity but undefined mechanisms, was studied for its anti-respiratory syncytial virus (RSV) mechanisms using network pharmacology and molecular docking, given RSV's substantial…