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living systematic review OR living systematic reviews: Latest results from PubMed
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Effectiveness and safety of acetazolamide plus loop diuretics in acute congestive heart failure: A living systematic review - Version 2026 1.0
Published: July 30, 2026 10:00
CONCLUSIONS: Evidence suggests that it is necessary to promote further investigations regarding the use of acetazolamide plus loop diuretics in acute congestive heart failure. More robust, standardized, long-term studies are needed, and conclusions may…
Safety, immunogenicity, efficacy, and effectiveness of mpox vaccines in pregnant persons, children, and adolescents: a protocol for a living systematic review and meta-analysis
Published: July 18, 2026 10:00
BACKGROUND: Mpox is a zoonotic disease caused by the monkeypox virus (MPXV) that became a global health concern following the 2022 outbreak. It poses a significant threat to immunocompromised individuals, children, and pregnant persons. Disease spread in…
Disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis after failure of biologic or targeted synthetic therapy: a systematic review and network meta-analysis
Published: July 13, 2026 10:00
RATIONALE: After inadequate response to first-line biologic or targeted synthetic (b/ts) disease-modifying antirheumatic drug (DMARD) therapy in adults with rheumatoid arthritis, there are numerous alternative DMARD options, and current understanding of…
Compliance with existing standards: overview comparing Cochrane with non-Cochrane living systematic reviews
Published: July 10, 2026 10:00
CONCLUSIONS: This overview highlights a lack of methodological consistency among LSRs, potentially stemming from a lack of awareness of Cochrane's LSR standards. One criterion to become living is that the topic is a priority for decision-making; however,…
Efficacy, safety and policy implications of anti-amyloid monoclonal antibodies for Alzheimer's disease: protocol for a living systematic review and meta-analysis
Published: July 9, 2026 10:00
CONCLUSIONS: This living systematic review will provide an up-to-date synthesis of the benefits and harms of anti-amyloid monoclonal antibodies to inform clinical decision-making and health-system planning in Alzheimer's disease.
Interventions to prevent or cease electronic cigarette use in children and adolescents
Published: July 3, 2026 10:00
RATIONALE: The prevalence of e-cigarette use has recently increased globally amongst children and adolescents. In response to this increase and emerging evidence about the potential harms of e-cigarettes in children and adolescents, leading public health…
Evidence map of appendicitis - a living systematic review with meta-analyses
Published: July 1, 2026 10:00
CONCLUSION: The Evidence Map of Appendicitis is the ultimate go-to source for evidence on appendicitis. Constantly updated and freely accessible via www.EVIglance.com and as mobile phone app. Clinical decision-making, evidence-based patient information are…
Systematic review on genetic polymorphisms associated with idiosyncratic drug-induced liver injury (iDILI): iDILInet as an interactive visualization tool
Published: June 29, 2026 10:00
Idiosyncratic drug-induced liver injury (iDILI) is a rare, dose-independent and unpredictable adverse reaction occurring at therapeutic drug exposure, and it presents a significant challenge for drug development and patient safety. Despite extensive…
What's the Meta Now? More Updates on the Problems with Systematic Reviews
Published: June 27, 2026 10:00
CONCLUSIONS: Across successive updates, problems with systematic reviews remain widespread and consistent rather than isolated. Incremental reporting improvements coexist with persistent concerns about transparency, bias, and representativeness. Future…
It is Not Only About Staying Alive: A Living Systematic Review of Social Care Strategies for Older Adults in Residential Care Facilities During the COVID-19 Pandemic
Published: June 24, 2026 10:00
SUMMARY: The COVID-19 pandemic has had a negative impact on older adults in geriatric residential care facilities worldwide. In Canada, the mortality rate in these care settings was particularly high. To curb the spread of the virus, social distancing and…