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living systematic review OR living systematic reviews: Latest results from PubMed
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Performance of CEUS LI-RADS v2017 major feature combinations: individual patient data meta-analysis
Published: February 18, 2026 11:00
CONCLUSION: CEUS LI-RADS demonstrated progressively higher PPVs from LR-3 to LR-5, supporting its ability to stratify risk across HCC categories. Major feature combinations performed similarly within each category, indicating internal consistency of the…
The landscape of artificial intelligence tools and platforms for evidence synthesis: a scoping review
Published: February 10, 2026 11:00
Evidence synthesis (ES) involves rigorous, reproducible methodologies, which are increasingly being presented as 'Living' systematic reviews. As such, ES are critical to evidence-informed decision-making processes, such as the development, implementation,…
Reperfusion Strategies for Acute Pulmonary Embolism: Design and Rationale of RECONNECT-PE - a Living Systematic Review and Meta-analysis
Published: February 5, 2026 11:00
CONCLUSION: This living meta-analysis will offer continuously updated, comparative evidence on reperfusion strategies for acute PE, with a focus on informing the role of catheter-based interventions in clinical decision-making.
Wearable-Derived Heart Rate Variability Across the Menstrual Cycle, Hormonal Contraceptive Use, and Reproductive Life Stages in Females: A Living Systematic Review
Published: January 16, 2026 11:00
CONCLUSIONS: Wearable-derived HRV is associated with differences across the menstrual cycle, oral contraceptive use, and reproductive life stages. This should be considered when presenting HRV metrics to female users. This may improve the interpretation of…
The accuracy of Apple Watch measurements: a living systematic review and meta-analysis
Published: January 9, 2026 11:00
Apple Watch provides continuous monitoring of physiological and behavioural health metrics, increasingly used to support health-care delivery. Yet, evidence regarding its measurement accuracy remains limited. We aimed to assess the accuracy of measurements…
Artificial intelligence in the workplace: a living systematic review protocol on worker safety, health, and well-being implications
Published: December 30, 2025 11:00
BACKGROUND: Advancements in artificial intelligence (AI) are transforming employment and working conditions in ways that shape the safety, health, and well-being of workers. We describe a protocol for a living systematic review (LSR) that will examine the…
Drug Development
Published: December 25, 2025 11:00
CONCLUSION: We present a practical approach to prioritising repurposed drugs to evaluate in the context of clinical AD. We would like to thank our patient and public contributors and the wider investigator team.
Topical medications for moderate-to-severe rosacea: protocol for a living systematic review and network meta-analysis
Published: December 21, 2025 11:00
INTRODUCTION: Rosacea is a chronic skin condition characterised by papules, pustules, transient erythema (flushing), persistent erythema, telangiectasia and phymatous changes. Rosacea can be associated with substantial effects on quality of life. Rosacea…
A semi-automated approach facilitated the assessment of the certainty of evidence in a network meta-analysis: Part 1 - Direct comparisons
Published: December 20, 2025 11:00
CONCLUSION: Automated judgements using established decision rules agreed with expert judgement for the vast majority of GRADE CoE ratings.
A semi-automated approach facilitated the assessment of the certainty of evidence for in a network meta-analysis: Part 2 - Indirect and Mixed comparisons
Published: December 18, 2025 11:00
CONCLUSION: Automated approaches facilitated CoE ratings for indirect and network estimates. Further work is required to define appropriate algorithms for intransitivity.