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Sleep Efficiency and Neurocognitive Decline in Atopic Dermatitis: A Systematic Review
Published: October 30, 2024 10:00
Atopic dermatitis is often accompanied by a lack of sleep efficiency, which may impact neurocognitive functions. This review assesses the association between sleep quality in atopic dermatitis patients and neurocognitive decline. Databases searched…
Dermoid Cysts of the Auricle: A Review of the Literature
Published: October 30, 2024 10:00
CONCLUSIONS: Dermoid cysts of the auricle are reported more frequently in individuals with lighter skin; however, this is likely due to reporting bias. Complete surgical excision can be used to treat patients successfully, with a very low risk of…
Variability of rehabilitation protocols for ulnar collateral ligament repair with suture tape augmentation
Published: October 30, 2024 10:00
CONCLUSION: Rehabilitation protocols for UCL repair with suture tape augmentation were often structured around a 5-phase program with RTS approaching 20 weeks. They utilized immobilization and range of motion restriction as well as strengthening and…
An Update on Clinically Evaluated Medicinal Plants for Psoriasis Management
Published: October 30, 2024 10:00
Psoriasis is a prevalent inflammatory disease affecting almost 0.5-5 % of the world population. Multiple treatment approaches have been developed to manage psoriasis so far. Although concerns exist in the long-term usage of conventional and biological…
Facilitators and barriers to implementing patient-reported outcomes in clinical oncology practice: a systematic review based on the consolidated framework for implementation research
Published: October 30, 2024 10:00
CONCLUSIONS: This systematic review integrated facilitators and barriers affecting PRO implementation in routine oncology clinical practice settings and categorized them through the CFIR framework. These influencing factors should be fully considered in…
Detection of cardiac neuroendocrine tumour metastases by somatostatin receptor PET/CT: a systematic review and meta-analysis
Published: October 30, 2024 10:00
CONCLUSION: Evidence-based data demonstrate that SSTR-PET/CT enables early and better detection of CNTM compared to other radiological imaging methods. CNTM are encountered with a pooled prevalence of 1.5% of NEN patients performing SSTR-PET/CT.…
Safety and efficacy of peroral endoscopic myotomy for treating achalasia in pediatric and geriatric patients: A meta-analysis
Published: October 30, 2024 10:00
CONCLUSION: Our findings demonstrated that POEM was an effective and safe technique for pediatric and geriatric patients with achalasia.
Brain functional alteration and cognitive performance in cardiovascular diseases: a systematic review of fMRI studies
Published: October 30, 2024 10:00
CONCLUSION: It can be extrapolated that CVDs tend to alter the brain network connectivity and result in cognitive impairment and poorer task performance. However, for future imaging studies, more stringent and homogenous demographic data are highly…
Evaluating the Impact of Different Treatments on the Quality of Life in Patients With Burning Mouth Syndrome: A Scoping Review
Published: October 30, 2024 10:00
The profound impact of burning mouth syndrome (BMS) on patients' quality of life (QoL) highlights the critical need to identify effective treatments for this condition. This study aims to evaluate and compare the health-related quality of life (HRQoL) and…
Acromioclavicular joint biomechanics: a systematic review
Published: October 30, 2024 10:00
CONCLUSION: This review highlights the key AP and superior-inferior constraints of both the intact and ligament sectioned AC joint. The inconsistency of AC joint testing parameters and the lack of thorough translation studies indicate a necessity for…
Exploring Risk Factors for Post-operative Complications in Laparoscopic Common Bile Duct Exploration: A Literature Review
Published: October 30, 2024 10:00
Gallstone-related diseases, particularly common bile duct (CBD) stones, pose a significant global health challenge. The emergence of laparoscopic common bile duct exploration (LCBDE) has transformed the management of these conditions by offering a less…
Effect of Temperature on Emergency Ambulance Call-Outs for Cardiovascular Causes: A Scoping Review
Published: October 30, 2024 10:00
Climate change has increased interest in the effects of the thermal environment on cardiovascular health. Most studies have focused on mortality data. However, pre-hospital care data are better able to evaluate these effects, as they can register the full…
Heterotopic ossification (HO) prophylaxis after distal biceps repair
Published: October 30, 2024 10:00
HYPOTHESIS AND BACKGROUND: A potential complication of distal biceps repair is heterotopic ossification (HO), which impacts both limb function and overall patient outcomes. Common HO prophylaxis methods include nonsteroidal anti-inflammatory drugs or…
Effects of Dignity Therapy for Palliative Care Patients and Family Caregivers: A Systematic Review
Published: October 30, 2024 10:00
Dignity Therapy (DT) is a psychosocial intervention aimed at alleviating existential distress, enhancing meaning, and improving the overall well-being of palliative care patients and their family caregivers. While individual studies have demonstrated the…
Coracoclavicular fixation techniques for Neer IIb and "extralateral" fractures of the distal clavicle: a systematic review
Published: October 30, 2024 10:00
CONCLUSION: The present systematic review of coracoclavicular stabilization techniques for unstable Neer IIb and extralateral fractures of the distal clavicle demonstrates promising clinical outcomes, including effectiveness and safety. We support the…
Tumor Budding in Upper Gastrointestinal Carcinomas: A Systematic Review and Meta-Analysis
Published: October 30, 2024 10:00
Gastrointestinal (GI) carcinomas represent a heterogeneous composition of malignancies that stem from the organs of the GI tract. They are among the most prevalent and are associated with high mortality alongside morbidity rates. This study utilized the…
The Efficacy and Safety of Inclisiran for Low-Density Lipoprotein (LDL) in Patients With Atherosclerotic Cardiovascular Disease (ASCVD): A Systematic Review of Randomized Controlled Trials
Published: October 30, 2024 10:00
This systematic review synthesizes current evidence to evaluate the safety and efficacy of inclisiran for lowering low-density lipoprotein cholesterol (LDL-C). A thorough search was conducted across four main databases - PubMed, Web of Science, SCOPUS, and…
High rates of return to sport after suprascapular nerve decompression: an updated systematic review
Published: October 30, 2024 10:00
CONCLUSION: Suprascapular neuropathy treated with SSND significantly improves patient-reported outcomes and is noninferior to similar procedures without SSND. Appropriate clinical diagnosis of suprascapular neuropathy is required as opposed to a routine…
Association between 5-HTR1A gene C-1019G polymorphism and antidepressant response in patients with major depressive disorder: A meta-analysis
Published: October 30, 2024 10:00
CONCLUSION: This meta-analysis does not support a significant association between the 5-HTR1A C-1019G polymorphism and the efficacy of antidepressant treatment in MDD. The findings call for further research with larger cohorts to substantiate these results…
Evaluating the impact of transcranial electrical stimulation on post-stroke dysphagia: a systematic review and meta-analysis
Published: October 30, 2024 10:00
CONCLUSION: TES may improve swallowing in stroke patients, with potential benefits from low-intensity protocols.
Mechanism of imipenem-induced mental disorder: A meta-analysis
Published: October 30, 2024 10:00
CONCLUSION: Imipenem can cause mental disorders in patients. However, the low quality of the included literature may have affected the final results. Therefore, it is necessary to conduct a high-quality randomized controlled study with multiple samples to…
Arthroscopic reduction internal fixation for displaced radial head fractures: a systematic review of the outcomes and complications
Published: October 30, 2024 10:00
CONCLUSION: ARIF is a safe and viable option for treating displaced radial head fractures. It provides less soft tissue trauma and causes less stiffness compared to ORIF.
Exploring emotional intelligence in children using the trait emotional intelligence questionnaire: a systematic review
Published: October 30, 2024 10:00
CONCLUSIONS: This systematic review revealed that trait Emotional Intelligence measured via the TEIQue child forms provide reliable results and is valid, as it has been linked to key childhood variables. This review also provides guidance for future…
Spontaneous splenic rupture two days after laparoscopic sleeve gastrectomy
Published: October 30, 2024 10:00
IntroductionSleeve gastrectomy is a common bariatric procedure to manage morbid obesity. Splenic injury such as splenic rupture after sleeve gastrectomy is a rare complication which can be treated both with a splenectomy or conservative approach, called…
Metabolites Generated from Foods Through Lactic Fermentation and Their Benefits on the Intestinal Microbiota and Health
Published: October 30, 2024 10:00
Metabolites generated in foods with lactic fermentation have been subject of research in recent years due to different beneficial effects attributed to them on the microbiota and health in general, including their properties as antihypertensives,…
Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic review
Published: October 30, 2024 10:00
Maternal immunization (MI) is an emerging strategy to combat infant mortality in low-income (LIC) and lower-middle income countries (LMIC). We conducted a systematic review to identify the facilitators and barriers to MI and strategies that improve uptake…
Can International Classification of Disease Perinatal Mortality (ICD-PM) be a solution to overcome neglected tragedy? A scoping reviews
Published: October 30, 2024 10:00
CONCLUSION: The findings suggest that the utilization of ICD-PM on a global scale has been limited. The forthcoming advancement of ICD presents a chance to assess and enhance ICD-PM to establish it as a universally recognized standard system for…
Effects of Ginseng on Cognitive Function: A Systematic Review and Meta-Analysis
Published: October 30, 2024 10:00
Ginseng is a kind of traditional Chinese medicine. It is widely believed that ginseng can improve cognitive function, but its clinical efficacy is still controversial. This study aimed to systematically evaluate the effects of ginseng on cognitive function…
Can ChatGPT Be Used as a Research Assistant and a Patient Consultant in Plastic Surgery? A Review of 3 Key Information Domains
Published: October 30, 2024 10:00
CONCLUSION: ChatGPT can be a useful tool in the conception of and execution of literature searches and research information retrieval (with increased reliability when queries are specific); however, the technology is currently not reliable enough to be…
Efficacy of dextrose prolotherapy for temporomandibular joint hypermobility: A systematic review and meta-analysis
Published: October 30, 2024 10:00
CONCLUSIONS: Low-quality evidence suggests that dextrose prolotherapy may reduce MMO and improve pain scores compared to placebo in patients with TMJ hypermobility. Low-quality evidence also suggests that there may be minimal difference in outcomes between…
Incidence of immune effector cell-associated neurotoxicity among patients treated with CAR T-cell therapy for hematologic malignancies: systematic review and meta-analysis
Published: October 30, 2024 10:00
CONCLUSIONS: The overall incidences of ICANS with CAR T-cell therapy were 26.9% for all-grade and 10.5% for high-grade. Compared with other agents, patients with anti-CD19 drugs had a significantly increased risk of developing high-grade ICANS. Therefore,…
Knowledge gaps in diagnosing chronic polyneuropathy: Review of national guidelines
Published: October 30, 2024 10:00
The prevalence of chronic polyneuropathy will increase due to the aging population, and therefore, it becomes ever so important to optimize the diagnostic process. However, it is uncertain which blood tests are required and when nerve conduction studies…
The Trillat procedure: a systematic review of complications and outcome
Published: October 30, 2024 10:00
CONCLUSION: The Trillat procedure for recurrent anterior shoulder instability showed promising results, especially in selected cases, such as low-grade glenoid bone loss, with massive irreparable cuff tears or hyperlaxity.
The effect of Vagus nerve stimulation (VNS) on seizure control, cognitive function, and quality of life in individuals with drug-resistant epilepsy: A systematic review article
Published: October 30, 2024 10:00
OBJECTIVES: To evaluate the effect of vagus nerve stimulation (VNS) on seizure control, cognitive functions, and quality of life in individuals with drug-resistant epilepsy.
Prevalence of metabolic dysfunction-associated steatotic liver disease in people living with HIV and on antiretroviral treatment: A systematic review and meta-analysis protocol
Published: October 30, 2024 10:00
INTRODUCTION: Metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most common hepatic condition globally. The prevalence of MASLD continues to increase, paralleling the consistent rising rates of risk factors such as obesity and…
Complication rates of bone marrow aspirate concentrate injections versus other injectable therapies for knee osteoarthritis: A systematic review and meta-analysis
Published: October 30, 2024 10:00
CONCLUSIONS: Complication rates of BMAC injections are not significantly different from other injectables, nor specifically from HA for knee OA. Compared to other injections, 152 patients would need to receive a BMAC injection for one additional patient to…
Dosimetry Comparison of 3D Conformal Radiotherapy and Intensity-modulated Radiotherapy for the Treatment of Brain Tumors: A Meta-Analysis
Published: October 30, 2024 10:00
CONCLUSION: Our records suggested that IMRT with conventional linacs results in a meaningfully lower regular percentage of brain tumor volumes compared to 3D-CRT. Finally, this meta-analysis indicated that IMRT is better than 3D-CRT and decreases the…
Effectiveness of health education intervention on intention not to perform female genital mutilation/cutting in the future among key decision-makers: a systematic review and meta-analysis
Published: October 30, 2024 10:00
CONCLUSION: This review examined the impact of health education on key decisions-makers' intention not to perform FGM/C in the future. Although the pooled effect size estimate may have been influenced by heterogeneity, the results suggest that education…
AI in Clinical Trials and Drug Development: Challenges and Potential Advancements
Published: October 30, 2024 10:00
Artificial intelligence (AI) is one of the fastest-growing fields in various industries, including engineering, architecture, medical and clinical research, aerospace, and others. AI, which is a combination of machine learning (ML), deep learning (DL), and…
The Interplay of Inflammatory Bowel Disease (IBD) and Diabetes in Pediatrics: A Systematic Review
Published: October 30, 2024 10:00
The main objective of this study is to provide insights into the clinical problems and considerations in managing pediatric patients with both diabetes and inflammatory bowel disease (IBD) by summarizing the available information. We conducted a…
Outcomes of the effect of exercise on cognitive function in patients with depression: A meta-analysis
Published: October 30, 2024 10:00
CONCLUSION: Exercise could improve attention and information-processing speed in patients with depression, although improvements in executive function and memory are not significant.
A scoping review of COVID-19 vaccine hesitancy: refusal rate, associated factors, and strategies to reduce
Published: October 30, 2024 10:00
CONCLUSION: Vaccine hesitancy (VH) rate and the factors affecting it are different according to different populations, contexts, and data collection tools that need to be investigated in specific populations and contexts. The need to conduct studies at the…
Racial and Ethnic Disparities in Hip Fracture Surgery: A Systematic Review and Meta-Analysis
Published: October 30, 2024 10:00
CONCLUSIONS: This systematic review and meta-analysis found evidence of disparities in hip fracture surgery, with minority patients facing greater rates of surgical delay and perioperative complications. Even though the studies may not have been uniform in…
The Candida auris Infection After the COVID-19 Pandemic Seems to be an Urgent Public Health Emergency: A Call to Attention
Published: October 30, 2024 10:00
CONCLUSION: Without vaccines and effective treatment, its capacity to mutate and spread has detrimental effects on humans. Therefore, extensive research on drug development, quick, reliable diagnosis, and effective strategies for disease prevention and…
The diagnostic accuracy of urine-derived exosomes for bladder cancer: a systematic review and meta-analysis
Published: October 30, 2024 10:00
CONCLUSIONS: As a novel biomarker, urine-derived exosomes have significant diagnostic prospects in the diagnosis of BC. Nevertheless, their application in clinical settings still demands a considerable number of clinical trials to confirm their clinical…
Impact of Vitamin E Supplementation on High-Density Lipoprotein in Patients With Haptoglobin Genotype-Stratified Diabetes: A Systematic Review of Randomized Controlled Trials
Published: October 30, 2024 10:00
Background: Vitamin E, an essential micronutrient with antioxidant potential, can dramatically reduce the cardiovascular risk in individuals with haptoglobin (Hp) 2-2 genotype diabetes; however, the underlying mechanism remains unclear. Objective: The…
Milk Fat Globules: 2024 Updates
Published: October 30, 2024 10:00
Milk fat globules (MFGs) are a remarkable example of nature's ingenuity. Human milk (HM) carries contains 3-5% fat, 0.8-0.9% protein, 6.9-7.2% carbohydrate calculated as lactose, and 0.2% mineral constituents. Most of these nutrients are carried in these…
Multisensory sensitivity in relation to pain: a scoping review of terminology and assessment
Published: October 30, 2024 10:00
Chronic pain is a debilitating health problem affecting 20 million Americans annually. Most patients with chronic pain report negative impacts on daily function and quality of life, which can result in devastating emotional and financial stress. Although…
Complications of tunneled and non-tunneled peripherally inserted central catheter placement in chemotherapy-treated cancer patients: a meta-analysis
Published: October 30, 2024 10:00
CONCLUSIONS: The subcutaneous tunneling technology has advantages over normal technique in decreasing PICC-related complications for cancer patients undergoing chemotherapy.
Prevalence of colistin resistance in clinical isolates of Pseudomonas aeruginosa: a systematic review and meta-analysis
Published: October 30, 2024 10:00
CONCLUSION: The increase in colistin resistance in P. aeruginosa in recent years from 2% (in the period of 2006-2010) to 5% (in the period of 2020-2023) underscores the need for implementing infection prevention programs, using appropriate treatment…
Redefining Cognitive Domains in the Era of ChatGPT: A Comprehensive Analysis of Artificial Intelligence's Influence and Future Implications
Published: October 29, 2024 10:00
CONCLUSION: Building a socio-cognitive architecture for collective human-machine intelligence has significant potential. While ChatGPT offers impressive capabilities, over-reliance on it for cognitive tasks can lead to the erosion of essential skills. It…
Trend in serological and molecular diagnostic methods for Toxoplasma gondii infection
Published: October 29, 2024 10:00
CONCLUSIONS: By summarizing the advantages and disadvantages of different diagnostic techniques, it is hoped that the epidemiology, prevention, and control of toxoplasmosis will be improved in the future through the use of appropriate technologies.
Association between improved erectile function and dietary patterns: a systematic review and meta-analysis
Published: October 29, 2024 10:00
Erectile dysfunction (ED) is prevalent among men, but its relationship with dietary habits is uncertain. The aim of our study was to assess whether dietary patterns enhance erectile function by reviewing the literature published before August 1, 2022, via…
Efficacy and safety of stem cell therapy for fistula management: An overview of existing systematic reviews
Published: October 29, 2024 10:00
CONCLUSION: Stem cell therapy shows promise as an effective and safe treatment for fistulas, particularly in inducing remission and promoting closure of complex fistulas. The findings advocate for further high-quality research to confirm these benefits and…
Effects of virtual reality rehabilitation after spinal cord injury: a systematic review and meta-analysis
Published: October 29, 2024 10:00
CONCLUSION: VR has shown promise in enhancing walking ability and balance function in individuals with SCI. However, the existing evidence for VR interventions in SCI patients remains limited, highlighting the necessity for future studies in this area.
Deep learning approach to predict autism spectrum disorder: a systematic review and meta-analysis
Published: October 29, 2024 10:00
CONCLUSIONS: DL techniques has satisfactory sensitivity, specificity, and AUC in ASD classification. However, the major heterogeneity of the included studies limited the effectiveness of this meta-analysis. Further trials need to be performed to…
Risk factors associated with stunting incidence in under five children in Southeast Asia: a scoping review
Published: October 29, 2024 10:00
CONCLUSIONS: This scoping review determined the risk factors for childhood stunting in Southeast Asia, such as attributes of the child, traits of the parent, the amount of food the child consumes, the health of the child, feeding habits, access to health…
Assessment of meniscal extrusion with ultrasonography: a systematic review and meta-analysis
Published: October 29, 2024 10:00
CONCLUSIONS: This systematic review suggests ultrasonography can play an important role in the measurement of meniscal extrusion, with results comparable to that of MRI. However, to what extent it can differentiate between physiological and pathological…
Prevalence of adenomyosis in adolescents: diagnostic process and symptoms. Systematic review
Published: October 29, 2024 10:00
BACKGROUND: Adenomyosis is a uterine disorder commonly associated with painful menstrual cycles, abnormal uterine bleeding, and dyspareunia, which can significantly impact fertility, pregnancy outcomes and overall quality of life. Recent literature reports…
Role of serum kisspeptin as a biomarker to detect miscarriage: a systematic review and meta-analysis
Published: October 29, 2024 10:00
Miscarriage is a common adverse pregnancy outcome with physical and emotional effects. Identifying predictive miscarriage biomarkers should improve early detection and management. Serum kisspeptin, known for its critical role in reproductive biology, has…
Normal ranges of left atrial phasic strains and strain rates by 2D speckle-tracking echocardiography in pediatrics: a systematic review and meta-analysis
Published: October 29, 2024 10:00
Establishing normal values of left atrial (LA) phasic strains and strain rates is essential for distinguishing between normal and abnormal functions, determining the degree of abnormality, and understanding the clinical significance of reported values in…
Enablers and Barriers of Healthcare Services for Community-Dwelling Elderly in Rural Indonesia: A Qualitative Evidence Synthesis: Facilitadores e barreiras dos serviços de saĂşde para os idosos das comunidades nas zonas rurais da IndonĂ©sia: uma sĂntese qualitativa das provas
Published: October 29, 2024 10:00
CONCLUSION: A collaboration between communities, healthcare institutions, families, and government authorities was needed to support the success of the program and maintain the sustainability of services, which will result in adequate healthcare for the…
Associations between amyloid-β load and cognition in cerebrovascular disease beyond cerebral amyloid angiopathy: a systematic review and meta-analysis of positron emission tomography studies
Published: October 29, 2024 10:00
CONCLUSIONS: Amyloid-β load is associated with cognitive decline in non-CAA CVD patients. This is more pronounced in patients with subcortical vascular disease than in post-stroke patients. Executive function is the most susceptible domain in VCI when the…
Gut microbiota in women with polycystic ovary syndrome: an individual based analysis of publicly available data
Published: October 29, 2024 10:00
BACKGROUND: Polycystic ovary syndrome (PCOS) represents a prevalent endocrine disorder affecting numerous females worldwide. Dysbiosis of gut microbiota has been linked to the occurrence of PCOS; however, research into the characteristics of gut microbiota…
Weight-control compensatory behaviors patterns and correlates: a scoping review
Published: October 29, 2024 10:00
CONCLUSION: Weight-control compensatory behaviors may be a widely used weight management strategy and can be presented in diverse ways. Although believed to be promoting health, such behaviors appear to be associated with poor psychological well-being.…
Periodontal disease and cardiovascular disease: umbrella review
Published: October 29, 2024 10:00
CONCLUSIONS: Systematic reviews with high overall confidence support the association between PD, tooth loss, and cardiovascular diseases. However, it is crucial to interpret these results with caution due to methodological limitations. The potential public…
What is known about patients' quality of life with Phenylketonuria and their caregivers? A scoping review
Published: October 29, 2024 10:00
CONCLUSION: Patients of pediatric age and their caregivers, younger caregivers, and female patients and caregivers seem to be especially vulnerable to QoL impairments. The social and emotional dimensions were the most affected. These results emphasize the…
Efficacy of Fresh Versus Preserved Amniotic Membrane Grafts for Ocular Surface Reconstruction: META = meta-analysis
Published: October 29, 2024 10:00
Amniotic membrane transplantation is commonly employed in ophthalmology to mend corneal epithelial and stromal defects. Its effectiveness in restoring the ocular surface has been widely acknowledged in clinical practice. Nevertheless, there is ongoing…
Cost-effectiveness of Evolocumab in Cardiovascular Disease: A Systematic Review
Published: October 29, 2024 10:00
CONCLUSIONS: Our systematic review concludes that Evolocumab could be a cost-effective treatment, particularly for high-risk patient groups, but this varies by disease category, risk level, and evaluation methods. Future studies should investigate the…
PET imaging of pheochromocytoma and paraganglioma - 18F-FDOPA vs. somatostatin analogues
Published: October 29, 2024 10:00
CONCLUSION: 18F-FDOPA and 68Ga-SSA PET are both sensitive for localizing PPGL. However, 18F-FDOPA is the most sensitive for detecting pheochromocytoma, while 68Ga-SSA is superior to 18F-FDOPA for metastatic sympathetic and head-neck paraganglioma and…
Sleep disorders associated with cranial radiation - a systematic review
Published: October 29, 2024 10:00
CONCLUSIONS: This systematic review highlights the ongoing challenges with sleep symptoms/disorders related to cranial irradiation treatment in the primary brain tumor population. Further investigations on the interconnectedness of sleep disturbance…
Deprescribing Antidepressants in Children and Adolescents: A Systematic Review of Discontinuation Approaches, Cross-Titration, and Withdrawal Symptoms
Published: October 29, 2024 10:00
Background: Antidepressant medications, including selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), are commonly used to treat depressive, anxiety, and obsessive-compulsive disorders in youth. Yet,…
Translation, Cultural Adaptation, and Content Validation of a Pleural Mesothelioma Questionnaire to Portuguese Context - A Key Tool for Epidemiological Surveillance
Published: October 29, 2024 10:00
CONCLUSION: A validated FNSPPM questionnaire for the Portuguese context is now available to study individuals with pleural mesothelioma (PM) and asbestos exposure.
A Comparative Analysis of Botulinum Toxin Use Versus Other Therapies for Temporomandibular Disorders: A Systematic Review
Published: October 29, 2024 10:00
Existing literature regarding the efficacy of Botulinum toxin A (BoNT-A) therapy in improving the clinical outcomes of temporomandibular disorders (TMDs) is ambiguous and lacks consistency. Thus, this study aimed to evaluate the efficacy of BoNT-A in…
Problems Related to Endotracheal Intubation as an Input for the Design of a New Endotracheal Tube
Published: October 29, 2024 10:00
OBJECTIVE: The purpose of the current review is to identify the main problems of endotracheal intubation, which will serve as a basis for the design requirements for a novel endotracheal tube.
Outcomes of Intramedullary Nailing Versus Plate Fixation in the Management of Humeral Shaft Fractures: A Systematic Review and Meta-Analysis
Published: October 29, 2024 10:00
This systematic review and meta-analysis aimed to compare the outcomes of intramedullary nailing (IMN) and open reduction with internal fixation (ORIF) in treating traumatic humeral shaft fractures in adults (18 years and above). A comprehensive literature…
Improving patient safety and access to healthcare: The role of pharmacist-managed clinics in optimizing therapeutic outcomes
Published: October 29, 2024 10:00
Contemporary patient care requires a multidisciplinary approach to monitoring, assessing, and managing diseases. Promoting multidisciplinary approaches encourages the purposeful participation of many healthcare professionals and harnessing their combined…
The Effects of Subsidies for Healthy Foods on Food Purchasing Behaviors, Consumption Patterns, and Obesity/Overweight: A Systematic Review
Published: October 29, 2024 10:00
CONCLUSION: Although the subsidies appear to encourage purchase and consumption of healthier foods, enhancing the quality and diversity of dietary choices, the removal of subsidies can lead to a decline in the consumption of healthier foods. Additionally,…
Upfront Surgery Versus Upfront Concurrent Chemoradiotherapy as Primary Modality in Hypopharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis
Published: October 29, 2024 10:00
CONCLUSIONS AND RELEVANCE: The results demonstrated that upfront surgery showed better OS and DFS than concurrent chemoradiation and remind the clinicians of the potential reduction in survival outcomes when choosing concurrent chemoradiotherapy as primary…
The role of Chinese herbal medicine in the regulation of oxidative stress in treating hypertension: from therapeutics to mechanisms
Published: October 29, 2024 10:00
CONCLUSIONS: CHM display a beneficial multi-target, multi-component, overall and comprehensive regulation characteristics, and have potential value for clinical application in the treatment of hypertension by regulating the level of oxidative stress.
The effect of different dietary restriction on weight management and metabolic parameters in people with type 2 diabetes mellitus: a network meta-analysis of randomized controlled trials
Published: October 29, 2024 10:00
CONCLUSIONS: Both IF and CER exert positive influences on weight control and metabolic profile enhancement in individuals with T2DM, with FMD as part of IF demonstrating the greatest impact. To substantiate these findings, more rigorous randomized…
The Implementation of the International Health Regulations on Vector-Borne Diseases: A Scoping Review of the Qualitative Evidence Performed Worldwide
Published: October 29, 2024 10:00
CONCLUSION: There are severe asymmetries across countries on the implementation of international regulations with regards to vector-borne diseases, particularly on the issue of surveillance systems. State Parties should consider the lessons learned from…
Post-Amputation Pain: Combined Analyses of Randomized Controlled Trials Evaluating Opioids and Gabapentinoids versus Placebo
Published: October 29, 2024 10:00
CONCLUSION: Patients undergoing limb amputation have a clear unmet need for more adequate chronic pain control. Given that post-amputation pain is often diagnosed as a chronic condition, persisting for at least 90 days, our data highlight the need for…
Perioperative use of enteral nutrition with ω-3 polyunsaturated fatty acid in patients with gastric cancer: a meta-analysis
Published: October 29, 2024 10:00
CONCLUSION: enteral nutrition with ω-3 polyunsaturated fatty acid preparation has advantages in the efficacy and safety of perioperative nutritional therapy in patients with gastric cancer, and can be used as a clinical choice. Due to the limited number…
Management Strategies for Immature Teeth with Pulp Necrosis: An Umbrella Review of Systematic Reviews
Published: October 29, 2024 10:00
CONCLUSIONS: MTA apexification and RET are viable alternatives to CH apexification, with RET showing greater potential for root development and apical healing. Future research should focus on developing standardized protocols and uniform RET guidelines,…
What Are the Barriers to Telerehabilitation in the Treatment of Musculoskeletal Diseases?
Published: October 29, 2024 10:00
CONCLUSION: The barriers to telerehabilitation, which were more related to Internet access, telecommunication devices, personal relationships, and adequate monitoring of the exercise protocol, were overcome by diversifying the means of communication and…
Safety and efficacy of intravenous thrombolytic therapy in the extended window up to 24 hours: A systematic review and meta-analysis
Published: October 29, 2024 10:00
OBJECTIVE: About 25% of patients with acute ischemic stroke (AIS) present within the intravenous thrombolytic (IVT) therapeutic window of <4.5 h. This study is to elucidate the safety and efficacy of IVT in the extended therapeutic window (ETW) in patients…
Clinical Outcomes of Exercise Rehabilitation for Degenerative Tibial Meniscal Tears: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Published: October 29, 2024 10:00
CONCLUSION: Exercise therapy has shown potential in alleviating pain, enhancing lower limb muscle strength, and improving mobility in patients with degenerative meniscal lesions of the tibia (DMLT). Functional training and varied rehabilitation exercises…
Patient-reported outcomes of chimeric antigen receptor T-cell therapy in hematologic malignancies: a systematic review and meta-analysis
Published: October 29, 2024 10:00
Few studies evaluated patient-reported outcomes (PROs) for patients with hematologic malignancies receiving with Chimeric Antigen Receptor T (CAR-T) cell therapy. We performed a systematic review and meta-analysis to evaluate the benefits of CAR-T cell…
Cost-effectiveness of oral versus injectable disease modifying therapies in relapsing multiple sclerosis: a systematic review analysis
Published: October 29, 2024 10:00
CONCLUSION: A large number of health economic evaluations of disease-modifying therapies (DMTs) in MS were available at the international level, the comparison of which was difficult and sometimes contradictory. However, despite the difference in the…
Updating the Pharmacological Effects of α-Mangostin Compound and Unraveling Its Mechanism of Action: A Computational Study Review
Published: October 29, 2024 10:00
α-Mangostin, initially identified in 1855, is a xanthone derivative compound predominantly located in the pericarp of the mangosteen fruit (Garcinia mangostana L). This compound is known for its beneficial properties as an antioxidant and anti-inflammatory…
Meta-analysis of the effects of probiotics on hyperlipidemia
Published: October 29, 2024 10:00
CONCLUSION: The findings from this meta-analysis suggest that probiotics can enhance SCFA content in the body, decrease lipid levels in animals, improve oxidative stress and inflammation, reduce liver damage, and effectively alleviate hyperlipidemia.
Oral Health Research in the WHO African Region between 2011 and 2022: A Scoping Review
Published: October 29, 2024 10:00
The status of oral health research in the World Health Organization (WHO) African region is unclear, yet the need for such information is central to moving an oral health agenda forward. Such an agenda is essential for effectively translating research into…
Artificial Intelligence in Forensic Sciences: A Systematic Review of Past and Current Applications and Future Perspectives
Published: October 29, 2024 10:00
The aim of this study is to review the available knowledge concerning the use of artificial Intelligence (AI) in general in different areas of Forensic Sciences from human identification to postmortem interval estimation and the estimation of different…
Global Cancer Nurse's Experiences and Perceptions of Potential Occupational Exposure to Cytotoxic Drugs: Mixed Method Systematic Review With Framework Synthesis
Published: October 29, 2024 10:00
CONCLUSIONS: The review conclude that individuals espouse safe handling and administration of CDs. Synthesis highlights a complex interplay between self-reported perception and the observed experience of potential occupational exposure to cytotoxic drugs.
Focal myositis: a literature review of clinical and immunopathological aspects
Published: October 29, 2024 10:00
CONCLUSIONS: Clinical, laboratory, neurophysiological and imaging findings can allow a correct diagnosis. However, muscle biopsy seems to be the only diagnostic tool to differentiate among FM and other localized soft tissue masses.
Exploring the Impact of Fasting and Fasting-Mimicking Diets on Type 2 Diabetes Management in Adults: A Systematic Review
Published: October 29, 2024 10:00
Type 2 diabetes poses significant global health challenges, affecting both the quality of life and healthcare systems. This systematic review evaluates the efficacy of fasting and fasting-mimicking diets (FMD) in managing type 2 diabetes, with a focus on…
Asbestos Exposure and Malignant Pleural Mesothelioma: A Systematic Review of Literature
Published: October 29, 2024 10:00
CONCLUSION: There is high evidence to support the relationships between asbestos and MPM. However, the relatively scant information provided by the studies reinforces the need for well-conducted research and implementation of National Mesothelioma…
Duration and Efficiency of Combined versus Isolated Aerobic Training Interventions in Post-Stroke Cognition: A Systematic Review
Published: October 29, 2024 10:00
BACKGROUND: This study aimed to evaluate the effects of physical activity on the cognition of patients with stroke, comparing the effectiveness of using isolated or combined rehabilitation, as well as the duration and intensity of training, to identify the…
Antimicrobial Effects of Formulations of Various Nanoparticles and Calcium Hydroxide as Intra-canal Medications Against Enterococcus faecalis: A Systematic Review
Published: October 29, 2024 10:00
The combination of calcium hydroxide (Ca(OH)₂) and nanoparticles (NPs) offers a promising approach to improving the efficacy of intra-canal treatments. Their synergistic effects can enhance antimicrobial action, improve penetration, and promote better…
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