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Multiple [TIAB] AND sclerosis [TIAB] AND therapy [TIAB] AND trial: Latest results from PubMed
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A network meta-analysis of the performance of acupoint stimulation therapy in improving fatigue, neurological function, and activities of daily living in patients with multiple sclerosis
Published: June 11, 2026 10:00
CONCLUSION: The application of acupoint stimulation therapy in combination with standard pharmacotherapy has demonstrated potential value in relieving fatigue, improving neurological function, and enhancing quality of life in patients with MS. However, due…
Task-oriented virtual reality and brain functional plasticity in progressive multiple sclerosis: A randomized controlled trial on upper limb rehabilitation
Published: June 10, 2026 10:00
CONCLUSION: In PMS treated with high-efficacy therapy, TO rehabilitation, particularly when combined with VR, can improve motor function, inducing functional gains and plasticity in cerebral networks.
Sustainable RP-HPLC Method Development for Simultaneous Estimation of Fampridine and Monomethyl Fumarate in Lipid Nanocarriers and Biological Fluids: Application of AQbd Principles
Published: June 5, 2026 10:00
Analytical quality by design (AQbD) provides a systematic framework for developing reliable pharmaceutical analytical methods. In this study, environmentally conscious RP-HPLC method was developed for fampridine and monomethyl fumarate, two…
Vitamin D for multiple sclerosis as an adjuvant therapy: A network meta-analysis of randomized controlled trials
Published: June 4, 2026 10:00
CONCLUSION: Vitamin D supplementation as an adjuvant therapy may reduce relapse and disability progression, with a favorable safety profile. These findings support the consideration of vitamin D supplementation in MS management, particularly in deficient…
The use of cladribine tablets in patients with MS beyond the age of 50: experiences from a large tertiary German centre
Published: June 3, 2026 10:00
CONCLUSIONS: Cladribine showed sustained effectiveness and an acceptable safety profile in MS patients over 50 years.
Disease-modifying treatment preferences and decision-making in a multiple sclerosis randomized and observational clinical trial (DELIVER-MS)
Published: May 31, 2026 10:00
CONCLUSION: Baseline DELIVER-MS data demonstrate that participants with milder disease are more likely to participate in RCT. The choice of EHT versus ESC was associated with demographic factors and disease activity.
Ketogenic Diet-Based Therapy for Fatigue in Patients with Multiple Sclerosis
Published: May 27, 2026 10:00
Background/Objectives: Fatigue is a frequent, disabling and difficult-to-treat symptom of multiple sclerosis (MS). Low-grade inflammation and energetic dysfunction have been proposed as mechanisms underlying the pathogenesis of this symptom. Owing to its…
Targeting non-apoptotic regulated cell death (RCD) to treat neurodegenerative diseases
Published: May 25, 2026 10:00
Regulated cell death (RCD) is well-known as a controlled form of cell death regulated by one or more cascading signaling pathways. Over the past few decades, increasing evidence has implicated various non-apoptotic forms of RCD in neurons-including…
Mesenchymal stromal/stem cell-derived extracellular vesicles in brain disorders: mechanisms of repair and recovery
Published: May 25, 2026 10:00
Mesenchymal stem/stromal cell-derived small extracellular vesicles (MSC-sEVs) have emerged as promising cell-free therapeutics for central nervous system (CNS) disorders including stroke, traumatic brain injury (TBI), dementia, and multiple sclerosis (MS).…
Game-based and gamification-enhanced telerehabilitation for physical therapy in people with multiple sclerosis: a scoping review
Published: May 23, 2026 10:00
CONCLUSION: GBT solutions may serve as a therapeutic alternative to conventional therapy, particularly when access to traditional services is limited or when individuals with MS experience reduced motivation to maintain their exercise routines. More…