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Neural implant smaller than a grain of salt can wirelessly track brain

https://medicalxpress.com/news/2025-11-neural-implant-smaller-grain-salt.html

Published: November 3, 2025 16:00

Cornell University researchers and collaborators have developed a neural implant so small that it can rest on a grain of salt, yet it can wirelessly transmit brain activity data in a living animal for more than a year.

Protein plays unexpected dual role in protecting brain from oxidative stress damage

https://medicalxpress.com/news/2025-11-protein-plays-unexpected-dual-role.html

Published: November 3, 2025 15:47

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.

Reduced synapse protein SNAP 25 found in patients with major depressive disorder and schizophrenia

https://medicalxpress.com/news/2025-11-synapse-protein-snap-patients-major.html

Published: November 3, 2025 14:32

People with major depressive disorder or schizophrenia have been found to have lower levels of the synaptic protein "SNAP-25" in their cerebrospinal fluid, according a study by University Medicine Halle that included more than 200 participants. Even though…

Massive database maps links between brain development and mental health

https://medicalxpress.com/news/2025-11-massive-database-links-brain-mental.html

Published: November 3, 2025 14:17

A new large-scale, open data resource from the Perelman School of Medicine and collaborators helps researchers link brain development with mental health disorders.

The right dose for the brain: Selenomethionine's role in protecting dopaminergic neurons

https://medicalxpress.com/news/2025-11-dose-brain-selenomethionine-role-dopaminergic.html

Published: November 3, 2025 13:30

Dopamine is often called the brain's "motivation molecule," but for me, it represents something deeper, a window into how fragile our neurons can be. The cells that produce dopamine, known as dopaminergic neurons, are among the first to die in Parkinson's…

Exploring the relationship between sleep and diet

https://medicalxpress.com/news/2025-10-exploring-relationship-diet.html

Published: November 3, 2025 13:00

Sleep patterns and eating habits can influence each other, but the link between these behaviors remains unclear. In a new JNeurosci paper, researchers led by William Ja, from the Herbert Wertheim UF Scripps Institute for Biomedical Innovation and…

Reward-related neurons drive risky decision-making differently in male and female rats

https://medicalxpress.com/news/2025-10-reward-neurons-risky-decision-differently.html

Published: November 3, 2025 13:00

Some people with psychiatric conditions, including addiction and attention deficit hyperactivity disorder, struggle to control their urges or make decisions under uncertainty. In a collaboration between the University of Cambridge and the University of…

Wearable brain imaging technology sheds new light on multiple sclerosis

https://medicalxpress.com/news/2025-11-wearable-brain-imaging-technology-multiple.html

Published: November 3, 2025 11:56

A study using wearable scanning technology has revealed how brain function differs in people with multiple sclerosis (MS). It is the first study to use this newly developed technology in MS and demonstrates its potential for studying neurological disease.

Small brain region linked to schizophrenia risk through unique gene changes

https://medicalxpress.com/news/2025-11-small-brain-region-linked-schizophrenia.html

Published: November 3, 2025 11:40

New research published in the American Journal of Psychiatry provides new molecular insights into the role of the habenula, a pea-sized brain region that helps regulate motivation and mood, in contributing to the risk of schizophrenia. A team of…

Detailed map of the developing human brain opens new pathways for Parkinson's treatment

https://medicalxpress.com/news/2025-11-human-brain-pathways-parkinson-treatment.html

Published: November 3, 2025 11:01

Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single cell maps of the developing human brain. The atlas captures nearly every cell type, their genetic fingerprints, and how they grow and…

When mice meet Beethoven: How early sound shapes the brain differently for males and females

https://medicalxpress.com/news/2025-11-mice-beethoven-early-brain-differently.html

Published: November 3, 2025 09:30

When Kamini Sehrawat and Prof. Israel Nelken of the Hebrew University of Jerusalem exposed baby mice to the first movement of Beethoven's Symphony No. 9, they weren't simply setting a mood. They were probing one of neuroscience's most intriguing questions:…

Holographic optogenetics could enable faster brain mapping for new discoveries

https://medicalxpress.com/news/2025-10-holographic-optogenetics-enable-faster-brain.html

Published: November 3, 2025 07:00

Recent technological advances have opened new possibilities for neuroscience research, allowing researchers to map the brain's structure and synaptic connectivity (i.e., the junctions via which neurons communicate with each other) with increasing…

Study finds surprising link between gut and brain rhythms

https://medicalxpress.com/news/2025-11-link-gut-brain-rhythms.html

Published: November 2, 2025 14:52

The human body is packed with natural rhythms, from your sleep-wake cycle to the steady pulsing of blood through the brain to heart rate and pulse.

Long-term study challenges assumptions about epilepsy recovery

https://medicalxpress.com/news/2025-10-term-assumptions-epilepsy-recovery.html

Published: November 2, 2025 11:50

Patients with treatment-resistant epilepsy often cycle through multiple medications as they seek relief from the seizures that disrupt their lives. Yet in many cases, these drugs offer little benefit, reinforcing the long-held belief among experts that…

Astringent, sharper mind: Flavanols can trigger brain activity for memory and stress response

https://medicalxpress.com/news/2025-10-astringent-sharper-mind-flavanols-trigger.html

Published: November 1, 2025 10:00

Astringency is a dry, puckering, rough, or sandpapery sensation in the mouth caused by plant-derived polyphenols. Polyphenols, including flavanols, are well known for risk reduction in cardiovascular diseases.

Neuronal hyperactivity and broader tuning linked to altered sound processing in autism model rats

https://medicalxpress.com/news/2025-10-neuronal-hyperactivity-broader-tuning-linked.html

Published: October 31, 2025 13:48

People with autism spectrum disorders commonly have difficulty processing sensory information, which can make busy, bright or loud settings—such as schools, airports and restaurants—stressful or even painful. The neurological causes for altered sound…

After distractions, rotating brain waves may help thought circle back to the task

https://medicalxpress.com/news/2025-10-distractions-rotating-brain-thought-circle.html

Published: October 31, 2025 13:17

As sure as the brain is prone to distraction, it can also return its focus to the task at hand. A new study in animals by scientists at the Picower Institute for Learning and Memory of MIT shows how that seems to happen: Coordinated neural activity in the…

Imaging study shows how brains go off-track in rare childhood disorder

https://medicalxpress.com/news/2025-10-imaging-brains-track-rare-childhood.html

Published: October 31, 2025 12:49

Researchers at the VIB-UAntwerp Center for Molecular Neurology have visualized how brain network development is altered in a model of KCNQ2-related developmental and epileptic encephalopathy, a rare childhood brain disorder. Using longitudinal imaging…

Researchers map how gut neurons respond to bacteria, parasites and food allergies

https://medicalxpress.com/news/2025-10-gut-neurons-bacteria-parasites-food.html

Published: October 31, 2025 11:38

The enteric nervous system (ENS) is a vast network of nerves built into the walls of the intestine. While it is well known for its role in regulating digestion and the movement of food through the intestine, researchers are learning that its influence…

'Frazzled' fruit flies help unravel how neural circuits stay wired

https://medicalxpress.com/news/2025-10-frazzled-fruit-flies-unravel-neural.html

Published: October 31, 2025 10:17

Florida Atlantic University neuroscientists have uncovered a surprising role for a protein named "Frazzled" (known as DCC in mammals) in the nervous system of fruit flies, showing how it helps neurons connect and communicate with lightning speed. The…

New clue to ALS and FTD: Faulty protein disrupts brain's 'brake' system

https://medicalxpress.com/news/2025-10-clue-als-ftd-faulty-protein.html

Published: October 31, 2025 09:20

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and…

What to know about tinnitus and other hearing problems

https://medicalxpress.com/news/2025-10-tinnitus-problems.html

Published: October 31, 2025 08:00

Susan Bianco, an 87-year-old from Lancaster, realized she was losing her hearing when she found herself constantly asking her husband to repeat himself. She was also struggling during phone calls and social events.

Genetic mechanisms reveal how toxic substances damage balance cells in the inner ear

https://medicalxpress.com/news/2025-10-genetic-mechanisms-reveal-toxic-substances.html

Published: October 30, 2025 17:00

The vestibular system is responsible for the sense of balance in the inner ear. Prolonged use of toxic substances, such as certain antibiotics or anticancer drugs, can damage the hair cells that form part of this system, leading to alterations in balance…

Previously unrecognized hub in the brain's lymphatic drainage system may assist with clearing waste

https://medicalxpress.com/news/2025-10-previously-unrecognized-hub-brain-lymphatic.html

Published: October 30, 2025 16:50

How does the brain take out its trash? That is the job of the brain's lymphatic drainage system, and efforts to understand how it works have pushed the boundaries of brain-imaging technologies.

New electrical signature of Parkinson's disease identified

https://medicalxpress.com/news/2025-10-electrical-signature-parkinson-disease.html

Published: October 30, 2025 15:33

What happens in the brain when a person experiences the characteristic movement symptoms of Parkinson's disease? Researchers around the world are seeking answers through various approaches. One of these builds on a treatment already established in clinical…

A promising molecule against chemotherapy-induced neuropathies

https://medicalxpress.com/news/2025-10-molecule-chemotherapy-neuropathies.html

Published: October 30, 2025 14:01

Currently incurable, peripheral neuropathies are common neurological complications of chemotherapy, causing persistent pain, tingling and burning sensations in the feet and hands, sometimes even after treatment has ended. In the hope of offering a…

Hundreds of animal studies on brain damage after stroke flagged for problematic images

https://medicalxpress.com/news/2025-10-hundreds-animal-brain-flagged-problematic.html

Published: October 30, 2025 14:00

A new study has identified over 240 scientific publications on animal models of hemorrhagic stroke that contain potentially problematic images, thereby raising concerns about the trustworthiness of the body of literature in this field.

Decoded circuits reveal how brain cell networks stabilize memory formation

https://medicalxpress.com/news/2025-10-decoded-circuits-reveal-brain-cell.html

Published: October 30, 2025 14:00

Newly decoded brain circuits make memories more stable as part of learning, according to a study led by NYU Langone Health researchers.

Chronic traumatic encephalopathy caused by more than just head trauma, study finds

https://medicalxpress.com/news/2025-10-chronic-traumatic-encephalopathy-trauma.html

Published: October 30, 2025 14:00

Chronic traumatic encephalopathy (CTE)—most often found in athletes playing contact sports—is known to share similarities with Alzheimer's disease (AD), namely the buildup of a protein called tau in the brain.

'Split-brain' study finds just a few fibers enable communication between the two hemispheres

https://medicalxpress.com/news/2025-10-brain-fibers-enable-communication-hemispheres.html

Published: October 30, 2025 13:10

Just a few fibers are enough for the two hemispheres of the brain to communicate with each other. This was shown by a new international study led by Professor Dr. Michael Miller (University of California, Santa Barbara) and Professor Dr. Lukas J. Volz…

Researchers patent formula to block the transition from acute to chronic pain

https://medicalxpress.com/news/2025-10-patent-formula-block-transition-acute.html

Published: October 30, 2025 12:34

Anyone who has experienced chronic pain knows how debilitating it can be. Just ask Daniele Piomelli, Ph.D., who has dealt with pain twice in his life: once after a minor surgery, and again with a bad bout of back pain that lasted for four months.

Virtual reality pool reveals feeling rewarded can help learn physical skills—even without actual rewards

https://medicalxpress.com/news/2025-10-virtual-reality-pool-reveals-rewarded.html

Published: October 30, 2025 12:11

People master new physical skills, such as sports, crafts or controlling a vehicle while driving, by blending lessons learned from both feedback on the amount of error they had in failures and the rewards of successes, even when reward cues are removed,…

Immature brain-supporting cells switch fate to restore blood flow after stroke

https://medicalxpress.com/news/2025-10-immature-brain-cells-fate-blood.html

Published: October 30, 2025 11:33

Stroke is a leading cause of death and disability, affecting 1 in 4 people during their lifetime. Stroke happens when blood vessels in the brain get clogged or damaged, impairing blood flow and oxygen supply to the brain, which leads to death of neurons…

Q&A: Customizing communication for children with visual impairment

https://medicalxpress.com/news/2025-10-qa-customizing-communication-children-visual.html

Published: October 30, 2025 08:20

A Penn State alumna turned faculty member is working to help improve communication solutions for children with a brain-based visual impairment.

Rapid blood pressure fluctuations linked to early signs of brain degeneration in older adults

https://medicalxpress.com/news/2025-10-rapid-blood-pressure-fluctuations-linked.html

Published: October 30, 2025 06:27

Even when blood pressure is well controlled, older adults whose blood pressure fluctuates widely from one heartbeat to the next may be at greater risk for brain shrinkage and nerve cell injury, according to a new study led by the USC Leonard Davis School…

Scientists on 'urgent' quest to explain consciousness as AI gathers pace

https://medicalxpress.com/news/2025-10-scientists-urgent-quest-consciousness-ai.html

Published: October 30, 2025 06:00

As AI—and the ethical debate surrounding it—accelerates, scientists argue that understanding consciousness is now more urgent than ever.

Combination of two blood biomarkers improves diagnostic accuracy in ALS

https://medicalxpress.com/news/2025-10-combination-blood-biomarkers-diagnostic-accuracy.html

Published: October 29, 2025 18:10

Despite modern imaging and genetic testing, diagnosing amyotrophic lateral sclerosis (ALS) remains challenging, particularly when distinguishing it from clinically similar neurodegenerative disorders.

Detailed brain growth atlas in mice offers insights into brain development

https://medicalxpress.com/news/2025-10-brain-growth-atlas-mice-insights.html

Published: October 29, 2025 16:50

Brain growth and maturation doesn't progress in a linear, stepwise fashion. Instead, it's a dynamic, choreographed sequence that shifts in response to genetics and external stimuli like sight and sound. This is the first high-resolution growth chart to…

Chemotherapy nerve damage linked to immune cell stress pathway activation

https://medicalxpress.com/news/2025-10-chemotherapy-nerve-linked-immune-cell.html

Published: October 29, 2025 16:20

Scientists at Wake Forest University School of Medicine, in collaboration with researchers at Weill Cornell Medicine, have made a breakthrough in understanding why many cancer patients develop nerve damage after chemotherapy. Their new study reveals that a…

Sensory expectations configure neural responses before disturbances occur, study reveals

https://medicalxpress.com/news/2025-10-sensory-configure-neural-responses-disturbances.html

Published: October 29, 2025 16:10

A study led by Jonathan Michaels, a Faculty of Health professor at York's School of Kinesiology and Health Science, reveals how the brains of humans and monkeys use sensory expectations to prepare for unexpected disturbances, enabling faster and more…

Veterans with epilepsy after traumatic brain injury may have higher mortality rates

https://medicalxpress.com/news/2025-10-veterans-epilepsy-traumatic-brain-injury.html

Published: October 29, 2025 16:00

Military veterans who develop epilepsy after a traumatic brain injury may have a higher mortality rate in the following years than veterans who develop epilepsy with no previous traumatic brain injury, according to a study published on October 29, 2025, in…

Who is more likely to lose vision due to high brain pressure?

https://medicalxpress.com/news/2025-10-vision-due-high-brain-pressure.html

Published: October 29, 2025 16:00

If untreated, a disorder of high brain pressure called idiopathic intracranial hypertension can lead to vision loss. But this disorder can develop without noticeable symptoms, making it hard to catch. A new study looks at how these vision problems develop…

Highly sensitive imaging technique detects myelin damage

https://medicalxpress.com/news/2025-10-highly-sensitive-imaging-technique-myelin.html

Published: October 29, 2025 15:41

The breakdown of myelin, the insulating layer around brain cells that supports brain function, is prevalent in a range of neurodegenerative diseases, aging and because of various forms of trauma. While electron microscopy is considered the gold standard…

Novel molecular mechanisms shape neuron identity in retinal cells

https://medicalxpress.com/news/2025-10-molecular-mechanisms-neuron-identity-retinal.html

Published: October 29, 2025 15:12

A recent study led by Tiffany Schmidt, Ph.D., associate professor of Ophthalmology and of Neurobiology in the Weinberg College of Arts and Sciences, has discovered previously unknown cellular mechanisms that shape neuron identity in retinal cells, findings…

Bioinformatics uncovers regenerative therapy for spinal cord injury

https://medicalxpress.com/news/2025-10-bioinformatics-uncovers-regenerative-therapy-spinal.html

Published: October 29, 2025 14:44

Spinal cord injury (SCI) remains a major unmet medical challenge, often resulting in permanent paralysis and disability with no effective treatments. Now, researchers at University of California San Diego School of Medicine have harnessed bioinformatics to…

The minimal circuit of the circadian clock: Just four neurons keep fruit flies on schedule, study finds

https://medicalxpress.com/news/2025-10-minimal-circuit-circadian-clock-neurons.html

Published: October 29, 2025 12:21

A tiny neural network is sufficient to control the daily rhythm of the fruit fly, Drosophila melanogaster. Researchers at the University of Würzburg have shown that only four specialized nerve cells are necessary to drive the animals' endogenous clock.

Discovery of 'doorstop' for brain's electrical gates may open path to new therapies for neurodegenerative conditions

https://medicalxpress.com/news/2025-10-discovery-doorstop-brain-electrical-gates.html

Published: October 29, 2025 12:10

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores that let charged ions enter a cell and the molecular…

Breakthrough treatment shows promise for smell loss after head injuries

https://medicalxpress.com/news/2025-10-breakthrough-treatment-loss-injuries.html

Published: October 29, 2025 11:56

A new treatment using platelet-rich plasma (PRP) injections has shown promising results in helping people recover their sense of smell after head injuries, according to a preliminary study published in the November issue of Otolaryngology–Head and Neck…

A newly-discovered mechanism could contribute to the therapeutic effects of deep brain stimulation

https://medicalxpress.com/news/2025-10-newly-mechanism-contribute-therapeutic-effects.html

Published: October 29, 2025 07:20

Deep brain stimulation (DBS) is a surgical procedure that entails the delivery of high-frequency electrical impulses to specific regions of the brain, via surgically implanted electrodes. While it requires an invasive surgical procedure, DBS can alleviate…

Oxytocin helps synchronize heartbeat and breathing, newly uncovered neural pathway suggests

https://medicalxpress.com/news/2025-10-oxytocin-synchronize-heartbeat-newly-uncovered.html

Published: October 29, 2025 06:30

When humans and other animals are in a calm state, they tend to breathe slower, and their heartbeat also slows down. Contrarily, when they are exercising or under psychological stress, both their breath and heartbeat tend to speed up.

Changing the 'packaging' of DNA in neurons can turn memories on or off in mice

https://medicalxpress.com/news/2025-10-packaging-dna-neurons-memories-mice.html

Published: October 29, 2025 06:00

Our experiences leave traces in the brain, stored in small groups of cells called engrams. Engrams are thought to hold the information of a memory and are reactivated when we remember, which makes them very interesting for research on memory and age- or…

Attention lapses due to sleep deprivation coincide with a flushing of fluid from the brain, research reveals

https://medicalxpress.com/news/2025-10-attention-lapses-due-deprivation-coincide.html

Published: October 29, 2025 06:00

Nearly everyone has experienced it: After a night of poor sleep, you don't feel as alert as you should. Your brain might seem foggy, and your mind drifts off when you should be paying attention.

Whole tablets may be safer than crushed ones for patients with poststroke swallowing disorders

https://medicalxpress.com/news/2025-10-tablets-safer-patients-poststroke-swallowing.html

Published: October 28, 2025 15:02

For decades, stroke patients with swallowing difficulties have routinely received crushed tablets to reduce the risk of aspiration. New clinical data now challenge this practice. A study using endoscopic swallowing diagnostics in patients with poststroke…

Previously unknown genetic cause of microcephaly identified

https://medicalxpress.com/news/2025-10-previously-unknown-genetic-microcephaly.html

Published: October 28, 2025 14:56

Microcephaly is a congenital malformation that leads to a significantly reduced brain size and is often accompanied by developmental delay. An international research team led by Dr. Tran Tuoc from the Department of Human Genetics at Ruhr University Bochum,…

Prenatal alcohol exposure rewires the brain and fuels compulsive behavior, new study finds

https://medicalxpress.com/news/2025-10-prenatal-alcohol-exposure-rewires-brain.html

Published: October 28, 2025 14:38

Fetal Alcohol Spectrum Disorders (FASD), a leading cause of neurodevelopmental disorders, may affect as many as 1 in 20 school-aged children in the United States. Despite its prevalence, the exact brain circuit responsible for FASD's hallmark…

How our brain understands human actions

https://medicalxpress.com/news/2025-10-brain-human-actions.html

Published: October 28, 2025 12:30

How do we recognize and interpret what others are doing—whether they're greeting a friend, preparing a meal together or doing sports? A new study authored by André Bockes, Ph.D. student at the Chair of Cognitive Neuroscience, and Prof. Angelika Lingnau, in…

Integrated platform enables precise production of human neural circuits in the lab

https://medicalxpress.com/news/2025-10-platform-enables-precise-production-human.html

Published: October 28, 2025 12:13

How do the circuits of the human brain work—and what happens when they are disrupted? To investigate these questions, researchers at the Eye Clinic of the University Hospital Bonn (UKB) and the University of Bonn, together with colleagues from the…

Dopamine found to increase willingness to wait for rewards in humans

https://medicalxpress.com/news/2025-10-dopamine-willingness-rewards-humans.html

Published: October 28, 2025 12:11

A research team from the University of Cologne conducted one of the most comprehensive studies on dopamine and decision-making in humans so far, providing evidence for effects of the former on the latter. Dopamine is a neurotransmitter involved in several…

How neurons go with the flow when migrating through the brain

https://medicalxpress.com/news/2025-10-neurons-migrating-brain.html

Published: October 28, 2025 11:50

Researchers have discovered how newly created neurons depend on blood flow in the adult brain to travel from their site of origin to their final location. The study in mice, published today in eLife, is described by the editors as fundamental.

Researchers identify tipping point that leads to rapid sleep onset

https://medicalxpress.com/news/2025-10-rapid-onset.html

Published: October 28, 2025 11:04

In the new study, researchers demonstrated that the human brain falls asleep abruptly, rather than gradually, with a "tipping point" marking the transition from wakefulness into sleep. They were then able to predict the momentary progression into sleep…

Exploring the emerging role of neuromodulation in managing treatment-resistant OCD

https://medicalxpress.com/news/2025-10-exploring-emerging-role-neuromodulation-treatment.html

Published: October 28, 2025 10:20

In an article published in Brain Medicine, a European research team presents a focused review of emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder (OCD).

Head trauma symptoms may linger longer for patients with certain risk factors

https://medicalxpress.com/news/2025-10-trauma-symptoms-linger-longer-patients.html

Published: October 28, 2025 09:30

A multi-institutional investigation found several early presentation characteristics that were associated with symptoms after mild traumatic brain injury.

'Colorado sober' movement ditches alcohol for cannabis, psychedelics

https://medicalxpress.com/news/2025-10-colorado-sober-movement-ditches-alcohol.html

Published: October 28, 2025 09:20

Everything in moderation. Including moderation. That's the idea behind the Colorado sober movement, an unofficial yet growing trend away from alcohol, and toward plant-based and psychedelic drugs.

Online Tai Chi is helping people with chronic knee pain

https://medicalxpress.com/news/2025-10-online-tai-chi-people-chronic.html

Published: October 28, 2025 08:03

Tai Chi is a slow, gentle mind-body exercise that has been shown to benefit a wide range of health conditions and is particularly effective for people with chronic knee pain caused by osteoarthritis.

Distinct brain features in football players may tell who is at risk of long-term traumatic disease

https://medicalxpress.com/news/2025-10-distinct-brain-features-football-players.html

Published: October 28, 2025 06:39

Brain scans from American football players reveal subtle differences in the brain's outer grooves when compared to scans from otherwise healthy men who never played contact or collision sports, a new study shows. Its authors say the findings could…

Creativity is good for the brain and might even slow down its aging: New study

https://medicalxpress.com/news/2025-10-creativity-good-brain-aging.html

Published: October 27, 2025 17:40

Creative experience might enhance brain health, which could slow down the brain's aging.

Rare brain cell may hold key to preventing schizophrenia symptoms

https://medicalxpress.com/news/2025-10-rare-brain-cell-key-schizophrenia.html

Published: October 27, 2025 15:31

Difficulty completing everyday tasks. Failing memory. Unusually poor concentration. For many people living with schizophrenia, cognitive challenges are part of daily life. Alongside well-known symptoms such as hallucinations and delusions, these…

Exploring a mechanism of psychedelics

https://medicalxpress.com/news/2025-10-exploring-mechanism-psychedelics.html

Published: October 27, 2025 13:00

Using psychedelics to treat psychiatric diseases has become less controversial as scientists continue to reveal their underlying mechanisms. In an eNeuro paper, researchers led by Pavel Ortinski, from the University of Kentucky, used male rats to assess…

Common cholesterol drug might protect against 'chemo brain'

https://medicalxpress.com/news/2025-10-common-cholesterol-drug-chemo-brain.html

Published: October 27, 2025 10:40

The most common cholesterol drug around might help protect cancer patients from "chemo brain."

40Hz sensory stimulation may benefit some Alzheimer's patients for years, small study suggests

https://medicalxpress.com/news/2025-10-40hz-sensory-benefit-alzheimer-patients.html

Published: October 27, 2025 09:57

A new research paper documents the outcomes of five volunteers who continued to receive 40Hz light and sound stimulation for around two years after participating in an MIT early-stage clinical study of the potential Alzheimer's disease therapy. The results…

New study reveals hidden burden of multiple sclerosis on quality of life

https://medicalxpress.com/news/2025-10-reveals-hidden-burden-multiple-sclerosis.html

Published: October 27, 2025 09:45

A major UK-wide study led by researchers based in Liverpool has revealed the profound impact of multiple sclerosis (MS) on health-related quality of life, with findings that could reshape how services and resources are allocated for people living with the…

Mitochondrial epilepsy could originate in a specific group of brain neurons

https://medicalxpress.com/news/2025-10-mitochondrial-epilepsy-specific-group-brain.html

Published: October 27, 2025 09:44

A team led by the UAB Institut de Neurociències (INc-UAB) has for the first time identified the mechanism behind a potentially fatal type of epilepsy, a symptom of mitochondrial diseases. The discovery, based on mouse models, challenges the traditional…

A 'bird's eye view' of how human brains operate

https://medicalxpress.com/news/2025-10-bird-eye-view-human-brains.html

Published: October 27, 2025 09:12

A new study provides the best evidence to date that the connection patterns between various parts of the human brain can tell scientists the specialized functions of each region.

Suspenseful movies shed light on aging and memory

https://medicalxpress.com/news/2025-10-suspenseful-movies-aging-memory.html

Published: October 27, 2025 08:54

As horror enthusiasts queue up their favorite Alfred Hitchcock films to welcome in the Halloween season, Brock University researchers have turned to the master of suspense for a different reason—to better understand how aging brains process events and form…

Music therapy during surgery reduces anesthetic use and stress responses, study finds

https://medicalxpress.com/news/2025-10-music-therapy-surgery-anesthetic-stress.html

Published: October 27, 2025 08:00

A study published in the journal Music and Medicine demonstrates that intraoperative music therapy significantly reduces the amount of propofol and fentanyl required during laparoscopic cholecystectomy performed under general anesthesia. Patients exposed…

Why does ALS take away body movement? The hidden burden that seals the fate of motor neurons

https://medicalxpress.com/news/2025-10-als-body-movement-hidden-burden.html

Published: October 27, 2025 06:00

ALS, also known as Lou Gehrig's disease, is among the most challenging neurological disorders: relentlessly progressive, universally fatal, and without a cure even after more than a century and a half of research. Despite many advances, a key unanswered…

Hippocampal hyper-maturity: Synaptic gene changes connect stress, anxiety and accelerated aging

https://medicalxpress.com/news/2025-10-hippocampal-hyper-maturity-synaptic-gene.html

Published: October 27, 2025 04:00

Researchers at Fujita Health University and the Tokyo Metropolitan Institute of Medical Science have uncovered a previously overlooked form of brain abnormality linked to anxiety: excessive maturation and aging in the hippocampus, a state they term…

Open-source software reveals complete 3D architecture of brain cells

https://medicalxpress.com/news/2025-10-source-software-reveals-3d-architecture.html

Published: October 24, 2025 11:50

The neurons in our brain that underlie thought connect to each other using tiny branch-like structures on their surfaces known as dendritic spines. Now scientists at Columbia's Zuckerman Institute and their colleagues have come up with powerful new…

Physical fitness, physical activity and screen time are tied to adolescents' brain function

https://medicalxpress.com/news/2025-10-physical-screen-adolescents-brain-function.html

Published: October 24, 2025 11:21

Physical fitness, physical activity and screen time are associated with brain mechanisms underlying mental health and learning, according to two recent studies from the University of Eastern Finland and Kuopio University Hospital. Research into the effects…

Spinal cord stimulation may help prevent excess mortality associated with chronic pain

https://medicalxpress.com/news/2025-10-spinal-cord-excess-mortality-chronic.html

Published: October 24, 2025 10:15

Treating chronic neuropathic pain with spinal cord stimulation may help prevent excess mortality associated with chronic pain, a new study from the University of Eastern Finland and Kuopio University Hospital shows. The findings were published in…

The hidden life of pericytes: Understanding how cerebral malaria breaks the blood-brain barrier

https://medicalxpress.com/news/2025-10-hidden-life-pericytes-cerebral-malaria.html

Published: October 24, 2025 09:09

Researchers have built a 3D human blood-brain barrier in the lab and discovered a key role of brain pericytes in cerebral malaria disease

How the brain's activity, energy use and blood flow change as people fall asleep

https://medicalxpress.com/news/2025-10-brain-energy-blood-people-fall.html

Published: October 24, 2025 05:00

A new study by investigators from Mass General Brigham has used next-generation imaging technology to discover that when the brain is falling asleep, it shows a coordinated shift in activity.

Newly discovered Alzheimer's mechanism is linked to brain inflammation

https://medicalxpress.com/news/2025-10-newly-alzheimer-mechanism-linked-brain.html

Published: October 23, 2025 15:48

Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists' understanding of how brain inflammation arises in Alzheimer's disease.

Neuroscientists show that spoken words can sharpen the sense of touch in ways music cannot

https://medicalxpress.com/news/2025-10-neuroscientists-spoken-words-sharpen-ways.html

Published: October 23, 2025 15:36

Language allows humans to convey thoughts and ideas—it is a central means of communication. However, language also influences how we perceive the world through our senses, as demonstrated by a new study from the Brain Language Laboratory at Freie…

Chronic traumatic encephalopathy rare among individuals with isolated brain injuries

https://medicalxpress.com/news/2025-10-chronic-traumatic-encephalopathy-rare-individuals.html

Published: October 23, 2025 14:00

Chronic traumatic encephalopathy (CTE) is more common in people who experience extensive repetitive head impacts, and infrequent among individuals with isolated brain injuries or less extensive impacts, researchers from the Brain Injury Research Center of…

Scientists find ways to boost memory in aging brains

https://medicalxpress.com/news/2025-10-scientists-ways-boost-memory-aging.html

Published: October 23, 2025 13:06

Memory loss may not simply be a symptom of getting older. New research from Virginia Tech shows that it's tied to specific molecular changes in the brain and that adjusting those processes can improve memory.

Listening to or playing music over 75 linked to up to 39% reduction in dementia risk, study finds

https://medicalxpress.com/news/2025-10-playing-music-linked-reduction-dementia.html

Published: October 23, 2025 12:10

Listening to music when you are over 70 years of age has been linked to a 39% reduction in the risk of dementia, according to a Monash University-led study of over 10,800 older people.

No evidence to justify 'cocoon therapy' for pediatric concussions found

https://medicalxpress.com/news/2025-10-evidence-cocoon-therapy-pediatric-concussions.html

Published: October 23, 2025 10:28

Through the 1990s and early 2000s, guidelines for treating a concussion called for complete mental and physical rest. Current guidelines recommend a gradual resumption of cognitive and physical activity while consistently remaining engaged in typical daily…

Vicarious touch is common than previously thought, with implications for empathy, ASMR and mental health

https://medicalxpress.com/news/2025-10-vicarious-common-previously-thought-implications.html

Published: October 23, 2025 10:27

If you have ever watched a frightening movie which seemed so real, you felt a physical sensation in your own body if the characters on screen were hurt, you could be experiencing a phenomenon known as vicarious pain.

Simple screening tool can help uncover underdiagnosed back condition, study finds

https://medicalxpress.com/news/2025-10-simple-screening-tool-uncover-underdiagnosed.html

Published: October 23, 2025 09:54

For millions of people living with back pain, the cause is often elusive. One underrecognized culprit is axial spondyloarthritis (axSpA)—a form of inflammatory arthritis that primarily affects the spine and sacroiliac joints of the hips. Left undiagnosed,…

Glia may play a larger role in shaping neural circuit function than previously thought

https://medicalxpress.com/news/2025-10-glia-play-larger-role-neural.html

Published: October 23, 2025 09:35

Neurons have dominated neuroscience research for decades, but a growing body of evidence suggests that a group of non-neuronal brain cells called glia may play an equal or greater role in shaping brain health and disease. The human brain contains as many…

Scanning the tongue to detect and track motor neuron disease

https://medicalxpress.com/news/2025-10-scanning-tongue-track-motor-neuron.html

Published: October 23, 2025 07:04

Standard MRI scans of a person's tongue could assist in the early detection and ongoing monitoring of motor neuron disease.

Dementia linked to problems with brain's waste clearance system

https://medicalxpress.com/news/2025-10-dementia-linked-problems-brain-clearance.html

Published: October 23, 2025 07:00

Problems with the brain's waste clearance system could underlie many cases of dementia and help explain why poor sleep patterns and cardiovascular risk factors such as high blood pressure increase the risk of dementia.

Alzheimer's disrupts circadian rhythms of plaque-clearing brain cells, mouse study shows

https://medicalxpress.com/news/2025-10-alzheimer-disrupts-circadian-rhythms-plaque.html

Published: October 23, 2025 05:00

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later…

Gum disease associated with changes in the brain, increased stroke risk

https://medicalxpress.com/news/2025-10-gum-disease-brain.html

Published: October 22, 2025 16:00

Adults with gum disease may be more likely to have signs of damage to the brain's white matter, called white matter hyperintensities, than people without gum disease, according to a study published in Neurology Open Access.

A new developmental disorder—variations in the UNC13A gene can cause neurological impairments in children

https://medicalxpress.com/news/2025-10-developmental-disorder-variations-unc13a-gene.html

Published: October 22, 2025 15:40

Whether we are writing an email, rushing for a bus, or humming a tune, every thought, feeling, and action relies on communication between our roughly 100 billion nerve cells. This exchange of information happens at synapses, where messenger substances are…

Fat or carbs? The neural mechanism underlying food choices revealed

https://medicalxpress.com/news/2025-10-fat-carbs-neural-mechanism-underlying.html

Published: October 22, 2025 14:00

Feeding in mammals is controlled by a complex neural system. Although several key neural pathways related to total calorie intake have been extensively studied, it is still unclear how food choices are regulated and how they influence overall feeding…

Tears could open new avenue for diagnosing and monitoring eye and neurodegenerative diseases

https://medicalxpress.com/news/2025-10-avenue-eye-neurodegenerative-diseases.html

Published: October 22, 2025 13:47

Ocular fluids provide a window into the health of the eye and the development of various pathologies. However, their study usually involves invasive techniques. "A wide range of eye diseases are being investigated, but the methods for obtaining aqueous…

Our brains evaluate food within milliseconds, long before we've decided to eat it, research reveals

https://medicalxpress.com/news/2025-10-brains-food-milliseconds-weve-reveals.html

Published: October 22, 2025 10:46

Imagine you're at the grocery store, standing before a selection of snacks. Seemingly without thinking, you skip over the rice crackers to pick out a bag of chips.

When we dream, does our brain wake up?

https://medicalxpress.com/news/2025-10-brain.html

Published: October 22, 2025 09:35

An international consortium of researchers has created the largest-ever database compiling records of brain activity during sleep and dream reports. One of the first analyses of the database confirmed that dreams do not occur only during REM sleep, but…