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Innovative semaglutide hydrogel could reduce diabetes shots to once a month

https://medicalxpress.com/news/2024-09-semaglutide-hydrogel-diabetes-shots-month.html

Published: September 7, 2024 18:10

French researchers have developed a new drug delivery system that could cut the dosing schedule for type 2 diabetes and weight control drug semaglutide to just once a month, according to new research to be presented at this year's annual meeting of the…

Antibody–drug conjugate I-DXd shows meaningful response in patients with extensive-stage small cell lung cancer

https://medicalxpress.com/news/2024-09-antibodydrug-conjugate-dxd-meaningful-response.html

Published: September 7, 2024 11:30

The antibody–drug conjugate ifinatamab deruxtecan (I-DXd) has shown clinically meaningful responses in pretreated patients with extensive-stage small cell lung cancer (ES-SCLC), according to an interim analysis of the Phase 2 IDeate-Lung01 study. The data…

Lack of workplace support after medication errors can worsen outcomes among health care professionals

https://medicalxpress.com/news/2024-09-lack-workplace-medication-errors-worsen.html

Published: September 6, 2024 12:25

Psychological distress is the most common negative outcome experienced by health care professionals after making medication errors, according to a new study from the University of Eastern Finland. After such events, turnover intentions and absenteeism were…

Research team investigates the relationship between cannabis use, sleep and memory

https://medicalxpress.com/news/2024-09-team-relationship-cannabis-memory.html

Published: September 5, 2024 16:25

The growing legal use of recreational and medical cannabis has generated an increased concern for potential side effects from long-term use, particularly regarding problems with memory and sleep. Until now, the effect of cannabis use on sleep and on memory…

Risky combinations of psychiatric drugs prescribed for young patients

https://medicalxpress.com/news/2024-09-risky-combinations-psychiatric-drugs-young.html

Published: September 5, 2024 15:43

A new study reveals that young patients treated with psychiatric medications receive potentially dangerous combinations with concerning frequency.

Research reports improved outcomes with mineralocorticoid receptor antagonists across different types of heart failure

https://medicalxpress.com/news/2024-09-outcomes-mineralocorticoid-receptor-antagonists-heart.html

Published: September 5, 2024 15:34

Mineralocorticoid receptor antagonists (MRAs) reduced the risk of cardiovascular death or heart failure (HF) hospitalization in patients with HF and reduced ejection fraction (HFrEF) and also in those with mildly reduced or preserved ejection fraction…

Study points to need for developing cannabis use guidelines for treating cancer-related pain

https://medicalxpress.com/news/2024-09-cannabis-guidelines-cancer-pain.html

Published: September 5, 2024 12:47

A recent study led by a University at Buffalo researcher suggests a paradigm shift in patient attitudes regarding perceptions of cannabis and prescription opioid use for pain management associated with cancer treatment.

Promising drug-like compounds found to have strong action against blood cancers

https://medicalxpress.com/news/2024-09-drug-compounds-strong-action-blood.html

Published: September 5, 2024 11:29

For researchers, projects can sometimes feel like babies, and there is nothing more satisfying than seeing your baby grow up. For William Tansey, professor of cell and developmental biology, this baby started 10 years ago when he and Stephen Fesik, Orrin…

Most U.S. seniors prescribed at least one drug, but many skip meds due to cost

https://medicalxpress.com/news/2024-09-seniors-drug-meds-due.html

Published: September 5, 2024 08:26

Too many U.S. seniors are skipping their prescription meds due to cost, and the problem is most acute among the poor and chronically ill, new data shows. The new study was published Sept. 5 in National Health Statistics Reports.

Insulin and metformin combo aids diabetic foot ulcer healing, new study finds

https://medicalxpress.com/news/2024-09-insulin-metformin-combo-aids-diabetic.html

Published: September 4, 2024 17:54

People with chronic diabetic foot ulcers could soon have a new way to treat their wounds for faster healing and fewer hospital stays. Researchers from Michigan State University and South Shore Hospital have uncovered that the combination of two common…

Neither adjunctive intravenous argatroban nor eptifibatide significantly improves ischemic stroke outcomes: Study

https://medicalxpress.com/news/2024-09-adjunctive-intravenous-argatroban-eptifibatide-significantly.html

Published: September 4, 2024 17:00

Stroke patients who survive a blood clot in the brain's blood vessels are prone to developing new blockages during their recovery periods, even if they receive vessel-clearing interventions. In an effort to avoid further clots, doctors at 57 sites around…

New guideline for Helicobacter pylori includes change to primary treatment recommendation

https://medicalxpress.com/news/2024-09-guideline-helicobacter-pylori-primary-treatment.html

Published: September 4, 2024 16:00

The American Journal of Gastroenterology has published a new guideline on the treatment of Helicobacter pylori (H. pylori) infection.

Drug discovery could prevent spread of childhood bone cancer

https://medicalxpress.com/news/2024-09-drug-discovery-childhood-bone-cancer.html

Published: September 4, 2024 16:00

Despite decades of advancement in treatment, cancer spreading to multiple parts of the body remains one of the biggest challenges facing patients and their health-care teams.

Ketamine clinics vary widely in pregnancy-related safeguards, study finds

https://medicalxpress.com/news/2024-09-ketamine-clinics-vary-widely-pregnancy.html

Published: September 3, 2024 14:50

More hospitals and clinics now offer patients ketamine therapy for severe depression, post-traumatic stress disorder and other mental health conditions that haven't responded to other treatments.

Oral anticoagulants should be paused before transcatheter aortic valve implantation, researchers say

https://medicalxpress.com/news/2024-09-oral-anticoagulants-transcatheter-aortic-valve.html

Published: September 3, 2024 10:25

There was no apparent benefit to continuing oral anticoagulants compared with interruption in patients undergoing transcatheter aortic valve implantation (TAVI), according to late-breaking research presented in a Hot Line session today at ESC Congress…

Taking Wegovy, Zepbound? One expert has dietary advice

https://medicalxpress.com/news/2024-09-wegovy-zepbound-expert-dietary-advice.html

Published: September 3, 2024 09:40

Folks taking weight-loss drugs like Wegovy or Zepbound might think they've found a shortcut to better health.

Novel low-dose triple single-pill combination shows efficacy and tolerability in two international trials

https://medicalxpress.com/news/2024-09-dose-triple-pill-combination-efficacy.html

Published: September 3, 2024 09:37

A low-dose triple single-pill combination was effective at lowering blood pressure (BP) in two trials presented in a Hot Line session today at ESC Congress 2024.

Beta-blockers do not affect patients' quality of life, study finds

https://medicalxpress.com/news/2024-09-beta-blockers-affect-patients-quality.html

Published: September 2, 2024 13:04

Long-term use of beta-blockers in patients with myocardial infarction and preserved heart function does not significantly change quality of life or well-being compared to no beta-blockers. This is according to a study from Karolinska Institutet and Uppsala…

Asundexian inferior to apixaban for stroke prevention in atrial fibrillation: Study

https://medicalxpress.com/news/2024-09-asundexian-inferior-apixaban-atrial-fibrillation.html

Published: September 2, 2024 10:51

Asundexian 50 mg daily was inferior to apixaban for stroke and systemic embolism prevention in high-risk patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session Sept. 1 at ESC Congress 2024.

Evening vs. morning dosing of blood pressure medication: No differences seen

https://medicalxpress.com/news/2024-09-evening-morning-dosing-blood-pressure.html

Published: September 2, 2024 10:44

In two trials, one in frail elderly patients, evening administration of BP-lowering medications had no clinical benefits over morning administration, according to late-breaking research presented in a Hot Line session August 31 at ESC Congress 2024.

Examining aspirin interruption or continuation in patients with coronary stents undergoing non-cardiac surgery

https://medicalxpress.com/news/2024-09-aspirin-patients-coronary-stents-cardiac.html

Published: September 2, 2024 10:42

Among patients undergoing non-cardiac surgery more than one year after coronary drug-eluting stent (DES) implantation, there was no difference with respect to ischemic outcomes or major bleeding between perioperative aspirin monotherapy and receiving no…

Single tablet with four BP-lowering drugs found more effective than taking three drugs in separate pills

https://medicalxpress.com/news/2024-09-tablet-bp-lowering-drugs-effective.html

Published: September 2, 2024 10:40

A single-pill combination of four BP-lowering medications was significantly more effective than a combination of three medications, according to late-breaking research presented in a Hot Line session August 31 at ESC Congress 2024.

Edoxaban outperforms edoxaban plus antiplatelet agent in patients with a-fib and stable coronary artery disease: Study

https://medicalxpress.com/news/2024-09-edoxaban-outperforms-antiplatelet-agent-patients.html

Published: September 2, 2024 10:39

Edoxaban monotherapy reduced net adverse clinical events compared with edoxaban plus a single antiplatelet agent, when used as long-term antithrombotic therapy, in patients with high-risk atrial fibrillation (AF) and stable coronary artery disease (CAD),…

Researchers explore barriers to effective structured medication reviews

https://medicalxpress.com/news/2024-09-explore-barriers-effective-medication.html

Published: September 2, 2024 09:54

Researchers at the University of Liverpool have captured important evidence across primary and secondary care to explore the barriers to implementing effective structured medication reviews (SMRs). These new findings have the potential to help up to 14…

Clinical trial finds finerenone reduces worsening heart failure and cardiovascular death

https://medicalxpress.com/news/2024-09-clinical-trial-finerenone-worsening-heart.html

Published: September 2, 2024 09:50

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an…