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The latest news on medicine, health, medications, medicines and prescriptions.

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Antidepressant withdrawal symptoms more common among long-term users, study finds

Published: May 22, 2025 04:29

People who have been taking antidepressants for more than two years are substantially more likely to experience withdrawal symptoms compared to short-term users when they come off the medication, finds a new study led by UCL researchers.

Generic drugs can be reliably supplied at big savings, study finds

Published: May 21, 2025 15:40

A new study finds that CivicaScript, a not-for-profit drug manufacturer in the US, can reliably supply essential generic medicines at a price that saves patients over 60%, and public and private insurers over 90%, demonstrating the potential of the…

Promising results of niraparib appear in patients with advanced melanoma

Published: May 21, 2025 15:07

Researchers at Sutter's California Pacific Medical Center (CPMC) in San Francisco, Calif. have discovered early signs of clinical benefit while testing niraparib, a PARP inhibitor, in patients with advanced melanoma whose tumors had specific genetic…

Combined oral contraceptives triple risk of cryptogenic stroke in young women, new study shows

Published: May 21, 2025 10:58

New research presented today at the European Stroke Organization Conference (ESOC 2025) held in Helsinki, May 21–23, revealed that the use of combined oral contraceptives (OCs) is associated with a threefold increase in the risk of cryptogenic ischemic…

Candidate drug that boosts protective brain protein in mice has potential to treat Alzheimer's disease

Published: May 21, 2025 09:17

As researchers work to improve treatment of Alzheimer's disease, new research by UCLA Health identified a candidate drug that reduces levels of a toxic form of a protein in the brain caused by the disease and improved memory in mice by boosting production…

Researchers identify promising treatment for fentanyl-xylazine overdoses

Published: May 20, 2025 17:26

Researchers at Marshall University have developed a promising treatment strategy to address overdoses involving fentanyl and the veterinary sedative xylazine, a combination increasingly linked to severe health complications and reduced effectiveness of…

Study advances cancer precision therapies by identifying patients who benefit from bexmarilimab treatment

Published: May 20, 2025 16:41

Researchers at the University of Turku, Finland, have taken a step towards more personalized and effective cancer treatments. A new study has identified the conditions under which the antibody drug bexmarilimab can activate the body's own defense system…

Virtual trial shows combo rescue inhaler nearly halves severe asthma attacks

Published: May 19, 2025 17:18

Findings from a first-of-its-kind virtual trial in pulmonary medicine, conducted at Rutgers and many other institutions, suggest adding an inhaled corticosteroid to rescue therapy could sharply reduce the danger of severe attacks for millions of people…

Allopurinol designated as the first orphan drug for Marfan syndrome treatment

Published: May 19, 2025 16:54

The European Medicines Agency (EMA) has designated allopurinol as the first orphan drug for the treatment of Marfan syndrome, a rare connective tissue disease which has no cure to date. This disease causes an aortic aneurysm (an abnormal dilation of the…

Drug typically used for opioid addiction could be long COVID treatment

Published: May 19, 2025 13:11

Low-dose naltrexone (LDN) has been identified as a potential treatment for Long COVID after a Griffith University study, published in Frontiers in Molecular Biosciences, found it restored cellular function in human cells.

Branched-chain amino acids supplements may harm male bodybuilders' fertility

Published: May 16, 2025 12:27

A new study published in Zygote reveals that common over-the-counter supplements popular with male bodybuilders and athletes may impact their fertility. This study comes amid a global decline in male fertility.

How common drugs can help viruses spread

Published: May 15, 2025 13:40

Drugs are supposed to help us get rid of disease, or at least alleviate the symptoms of them. It is therefore particularly unfortunate that—on the contrary— drugs can contribute to making us sicker. Many medications can have side effects, but some are…

Family doctors' research on medication dosage timing answers critical questions that 'otherwise don't get asked'

Published: May 15, 2025 08:31

A University of Alberta-led study has put to rest a long-standing controversy about the best time of day to take blood pressure medications—and in the process has created a powerful research network of family doctors to answer important primary care…

Ajovy clinical trial shows little improvement over placebo in migraine and depression

Published: May 15, 2025 06:55

Albert Einstein College of Medicine and Teva Pharmaceuticals, in collaboration with multiple international institutions, report findings on the efficacy of fremanezumab (sold as Ajovy by Teva) in reducing migraine frequency and depressive symptoms among…

Daratumumab may help cancer patients with low physical function to live longer, study finds

Published: May 14, 2025 17:07

How cancer patients relying on daratumumab feel physically before starting the therapy can predict how long they will live and how well they will respond to the anti-multiple myeloma (MM) drug, according to a new study published in the European Journal of…

Low-cost formulation reduces dose and increases efficacy of drug against parasitic worms

Published: May 14, 2025 16:09

A group of researchers has developed a new formulation for the only drug available on the market to treat helminths, as worms such as schistosomes and tapeworms are known. According to the World Health Organization (WHO), 400 million people worldwide…

Research raises concerns about the safety of long-term ADHD medication treatment in children

Published: May 14, 2025 15:50

A recent study by the University of Turku and the University of Helsinki in Finland and the Finnish Social Insurance Institution Kela reveals that the average duration of ADHD medication for children and adolescents is more than three years. However,…

Using an inhaler alone may not be enough to manage asthma

Published: May 14, 2025 08:43

Inhalers have been key to asthma management since the 1950s. The most common, salbutamol, comes in a familiar blue-colored inhaler (or "puffer").

Traditional Chinese medicinal fungi might show potential for central nervous system diseases

Published: May 14, 2025 07:50

Shandong researchers suggest that edible and medicinal fungi contain bioactive components with therapeutic potential for central nervous system (CNS) diseases. Findings offer evidence for the potential of these fungi to serve as novel pharmaceuticals or…

Study finds long-term eczema treatment benefits patients with delayed response

Published: May 13, 2025 12:46

New research from the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai reveals that patients with moderate-to-severe atopic dermatitis (eczema) who did not initially respond to biologic treatment may…

Lower doses of the GLP-1 agonist medication as effective as higher ones, Danish study finds

Published: May 13, 2025 09:50

New research being presented at the European Congress on Obesity (ECO 2025) has found that patients of an online obesity clinic achieved similar weight loss to that reported in clinical trials—but with less than half the medication. The study is to be…

Interruptions disrupt pharmacy flow, risking safety

Published: May 13, 2025 08:41

A new study has found that phone calls, face-to-face consumer inquiries and out-of-scope questions from staff are the main sources of distraction during the dispensing process in pharmacy settings.

Migraine drug can also help with symptoms that occur before the actual headache begins

Published: May 12, 2025 15:40

A drug to treat migraine, ubrogepant, is also found to reduce common non-headache symptoms that occur in the hours preceding a migraine headache, according to the results of a large phase three clinical trial published in Nature Medicine. The findings…

Social, cultural and economic status can affect risk of receiving risky medication

Published: May 12, 2025 15:40

People with low wealth and income have up to 85% higher risk of receiving risky medication compared to the most affluent Danes. This is shown by a comprehensive national study led by researchers from Aarhus University, published in the journal PLOS…

Endometriosis: Daily pill to manage symptoms will soon be available on the NHS—here's how linzagolix works

Published: May 12, 2025 11:24

A daily pill to treat endometriosis has just been recommended by the National Institute for Health and Care Excellence (Nice). Once available on the NHS, linzagolix will provide a new treatment option for those who have been unable to manage the condition…

Do wellness patches work? How to tell the good from the bad

Published: May 12, 2025 11:16

From sleep aids and stress relief to vitamins and energy boosts, wellness patches are surging in popularity. These stick-on supplements promise to deliver nutrients and plant-based compounds directly through your skin and into your bloodstream—no pills, no…

Drug to slow Alzheimer's well tolerated outside of clinical trial setting, study finds

Published: May 12, 2025 11:00

The Food and Drug Administration's approval in 2023 of lecanemab—a novel Alzheimer's therapy shown in clinical trials to modestly slow disease progression—was met with enthusiasm by many in the field as it represented the first medication of its kind able…

Opioid prescribing standards changed practices in British Columbia, but with caveats

Published: May 12, 2025 00:10

In an effort to curb misuse of opioids and prevent overdose deaths, the College of Physicians and Surgeons of British Columbia released a legally enforceable practice standard, "Safe Prescribing of Drugs with Potential for Misuse/Diversion," in 2016. This…

Weight-loss drugs cut alcohol intake by almost two-thirds, research in Ireland suggests

Published: May 9, 2025 18:10

Individuals who take liraglutide or semaglutide for weight loss reduce their alcohol consumption by almost two-thirds in four months, new research presented at the European Congress on Obesity (ECO 2025) has found.

Foam treatment rapidly relieves itch and clears stubborn scalp psoriasis lesions

Published: May 9, 2025 09:12

Research led by the SKiN Center for Dermatology observed substantial clearance of scalp and body psoriasis and rapid itch reduction in patients treated with roflumilast foam, 0.3%. Findings indicated significantly higher rates of clinical improvement in…

Fighting infections while expecting: Research examines safe antibiotic use during pregnancy

Published: May 9, 2025 07:08

Pregnant women often think--or are told--that they cannot take medications during pregnancy to avoid harming the mom or baby. But one University of Mississippi professor is hoping new research will help medical professionals reexamine those…

When statins aren't enough, this drug may help lower 'bad' cholesterol

Published: May 8, 2025 16:01

A new drug combo lowers "bad" LDL cholesterol for people whose levels remain high even after taking statins. The new pill pairs a new drug called obicetrapib with an existing one, ezetimibe. In a Phase 3 clinical trial, this combo reduced LDL levels by…

Wireless device enables precise activation of light-sensitive pain drugs in animal study

Published: May 8, 2025 14:58

Photoactivable drugs are activated when irradiated by a beam of light—via an optical fiber—thus generating a controlled and local therapeutic effect on target tissues. Now, a scientific team has pioneered a new breakthrough in the field of…

HIV drugs offer 'substantial' Alzheimer's protection, new research suggests

Published: May 8, 2025 13:11

UVA Health scientists are calling for clinical trials testing the potential of HIV drugs called NRTIs to prevent Alzheimer's disease after discovering that patients taking the drugs are substantially less likely to develop the condition. The researchers…

Moxidectin could provide a faster route to eliminating parasitic infection endemic to Africa

Published: May 7, 2025 15:14

Tens of millions of people in Africa are infected by parasitic worms that cause lymphatic filariasis (also called elephantiasis), a disease that leads to severe swelling and deformities of the limbs and genitals. Despite widespread treatment programs that…

Quality improvement program aids antibiotic duration for common infections in children

Published: May 7, 2025 13:10

A quality improvement program can improve recommended antibiotic duration in children for both acute otitis media (AOM) and community-acquired pneumonia (CAP) across multiple care delivery settings, according to a study presented at the annual meeting of…

How a cholesterol drug may prevent heart attacks

Published: May 6, 2025 15:47

A new study conducted at Cedars-Sinai reveals how the cholesterol-reducing drug evolocumab prevents heart attacks in people with coronary artery disease—a leading cause of death in the United States.

Alzheimer's: Certain combinations of prescription drugs may slow progression of disease, according to mice study

Published: May 6, 2025 13:10

Millions of older adults take five or more prescription drugs every day to manage chronic illnesses. While polypharmacy is often necessary, this practice has also been linked to many negative health outcomes in older adults—including memory problems,…

Pooled buying can reduce costs of life-saving drugs, but planning is key

Published: May 6, 2025 12:23

Pooling orders for life-saving medicines can help drive down their cost and ensure a steady supply for low- and middle-income countries, though there are trade-offs, according to a new study led by a University of Massachusetts health economist and…

Lifesaving opioid addiction meds are rarely started after emergency visits for overdose

Published: May 6, 2025 11:49

Medications proven to effectively treat opioid addiction are rarely given after emergency department visits for overdose, and who gets them varies, sometimes greatly, depending on race, ethnicity or geography, University of Michigan researchers say.

Diabetes drug shows potential to slow prostate cancer cell growth

Published: May 6, 2025 10:54

An international team of scientists led by the Medical University of Vienna has identified similarities in the mechanisms of diabetes and cancer: as the researchers show, the protein PPARγ, which is central to the regulation of metabolic processes, can…

Single-dose gel clears ear infections in animal study within 24 hours

Published: May 5, 2025 16:56

Ear infections are a common and painful occurrence in infants and toddlers. Oral antibiotics are often prescribed for a week to treat the condition, but these drugs can trigger side effects that disrupt treatment, which can lead to infection recurrence and…

Drug resistance worsens UTI crisis in Malawi

Published: May 5, 2025 14:18

A growing resistance to antibiotics is complicating the treatment of urinary tract infections (UTIs) in Malawi, with new research revealing that nearly half of women presenting with symptoms at a major referral hospital had infections resistant to multiple…

Preterm infant with drug-resistant seizures responds to antisense oligonucleotide treatment

Published: May 5, 2025 10:00

Ludwig-Maximilians-Universität München-led researchers have induced a greater than 60% reduction in seizure frequency in a preterm infant with early-onset SCN2A developmental and epileptic encephalopathy (DEE). Seizures initially occurred at a rate of 20…

Promising Parkinson's drug decoded

Published: May 5, 2025 09:55

How well our brain functions depends heavily on the performance of our nerve cells. That is why they are regularly checked for their proper function—defective cell components are marked, disposed of and recycled. This includes the mitochondria, the…