RSS Parrot

Once-daily oral icotrokinra outperforms placebo in ulcerative colitis

https://medicalxpress.com/news/2026-10-daily-oral-icotrokinra-outperforms-placebo.html

Published: October 23, 2026 22:00

For patients with moderately to severely active ulcerative colitis, oral icotrokinra, a peptide that blocks the interleukin-23 receptor, yields a clinical response at week 12 significantly more often than placebo, according to a study published in the Oct.…

Tegoprubart preserves kidney function better than tacrolimus in first-time transplant patients, trial suggests

https://medicalxpress.com/news/2026-10-tegoprubart-kidney-function-tacrolimus-transplant.html

Published: October 23, 2026 18:30

The phase 2 BESTOW clinical trial showed that tegoprubart (a novel anti-CD40L antibody therapy) was better at preserving kidney function than tacrolimus (the current standard of care) in immunosuppressive regimens in adults receiving their first kidney…

Standard kidney function tests underestimate chronic kidney disease in people with cancer

https://medicalxpress.com/news/2026-10-standard-kidney-function-underestimate-chronic.html

Published: October 23, 2026 18:30

New research indicates that commonly used measures of kidney function underestimate the prevalence of chronic kidney disease (CKD) in patients with cancer. The findings will be presented at ASN Kidney Week 2026, Oct. 22–25.

Cancer cells' own carbon monoxide fuels anticancer drug production in lab tests

https://medicalxpress.com/news/2026-10-cancer-cells-carbon-monoxide-fuels.html

Published: October 23, 2026 13:40

What if we could use a cancer's own byproduct to make drugs that destroy tumor cells from the inside? That is what Katsunori Tanaka and his team have done at the RIKEN Pioneering Research Institute (PRI) in Japan.

FDA approves hepatitis B shot that may let some patients stop all treatment

https://medicalxpress.com/news/2026-10-fda-hepatitis-shot-patients-treatment.html

Published: October 23, 2026 13:00

Some adults with chronic hepatitis B may now have a path to something today's treatments rarely deliver—stopping all medication while the virus stays in check.

How psilocybin reshapes brain circuits

https://medicalxpress.com/news/2026-10-psilocybin-reshapes-brain-circuits.html

Published: October 23, 2026 12:40

A new study led by researchers at the University of California, Santa Cruz, reveals how psilocybin, the psychoactive compound in "magic mushrooms," reshapes neural connections in the brain.

Study finds patients experienced rapid weight gain after starting antipsychotic medication

https://medicalxpress.com/news/2026-10-patients-experienced-rapid-weight-gain.html

Published: October 23, 2026 11:20

People with severe mental illness experienced more rapid increases in both weight and long-term blood sugar levels during the first three months after starting treatment with antipsychotic medication, according to a study from Karolinska Institutet and…

Potassium binder may ease the burden of dietary potassium restriction in people on dialysis

https://medicalxpress.com/news/2026-10-potassium-binder-ease-burden-dietary.html

Published: October 22, 2026 18:30

Dietary potassium restriction is important for managing hyperkalemia, or high blood potassium levels, in individuals on maintenance hemodialysis, but it imposes a substantial day-to-day burden. Results from a recent clinical trial indicate that adding the…

Early uptake for oral semaglutide proves rapid relative to injectables

https://medicalxpress.com/news/2026-10-early-uptake-oral-semaglutide-rapid.html

Published: October 22, 2026 18:20

Early uptake was rapid for oral semaglutide (Wegovy pill) relative to injectable incretin-based weight management therapies, according to a study published online Oct. 13 in Annals of Internal Medicine.

ADHD medication unlikely to raise risk of self-harm, international study finds

https://medicalxpress.com/news/2026-10-adhd-medication-international.html

Published: October 22, 2026 18:00

The risk of self-harm among people with attention deficit hyperactivity disorder (ADHD) is highest before people start ADHD medication, rather than after treatment begins, according to new research led by Aston University and recently published in the…

Common multiple sclerosis treatment linked to bowel disease risk

https://medicalxpress.com/news/2026-10-common-multiple-sclerosis-treatment-linked.html

Published: October 22, 2026 17:00

People with multiple sclerosis (MS) who are treated with rituximab have an increased risk of developing inflammatory bowel disease, particularly Crohn's disease, although the absolute risk remains low. This is according to the first large population-based…

International study helps support FDA approval of HIV drug for newborns

https://medicalxpress.com/news/2026-10-international-fda-hiv-drug-newborns.html

Published: October 22, 2026 16:40

An international study conducted through the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network, including researchers at the University of California San Diego, helped inform the U.S. Food and Drug Administration's (FDA)…

New AI platform helps uncover promising cancer drug combinations

https://medicalxpress.com/news/2026-10-ai-platform-uncover-cancer-drug.html

Published: October 22, 2026 16:00

UCLA investigators have developed a new artificial intelligence-based platform that could help scientists identify promising drug combinations to overcome treatment resistance in cancer.

Lab study shows needle-free mRNA vaccine protects against COVID and flu

https://medicalxpress.com/news/2026-10-lab-needle-free-mrna-vaccine.html

Published: October 22, 2026 12:20

A needle-free vaccination method protected mice against the viruses that cause COVID-19 and flu, offering a possible new way to deliver mRNA vaccines while limiting unwanted inflammation.

GLP‑1 weight‑loss drugs change how people eat, but nausea needs closer study

https://medicalxpress.com/news/2026-10-glp1-weightloss-drugs-people-nausea.html

Published: October 22, 2026 11:40

Someone taking a weight-loss drug might leave half their dinner because they feel comfortably full. They might also stop because they feel nauseous. Measuring the leftovers would reveal the same result, but tell researchers little about why the person…

Clinical trials generate promising results for improving kidney health

https://medicalxpress.com/news/2026-10-clinical-trials-generate-results-kidney.html

Published: October 22, 2026 10:00

The results of numerous high-impact Phase III clinical trials that could affect kidney-related medical care were presented in person at American Society of Nephrology Kidney Week 2026, Oct. 22–25.

Rebalancing the body's cellular communication system could slow aging

https://medicalxpress.com/news/2026-10-rebalancing-body-cellular-communication-aging.html

Published: October 22, 2026 05:00

Researchers have outlined a plan for slowing aging by targeting one of the body's most important cellular communication systems. In a new paper published in Frontiers in Science, scientists describe how novel therapies that modulate GPCR signaling could…

FDA patient, consumer reps often tied to pharma-funded groups

https://medicalxpress.com/news/2026-10-fda-patient-consumer-reps-pharma.html

Published: October 21, 2026 22:40

Patient and consumer representatives advising U.S. Food and Drug Administration (FDA) expert panels might actually be a Trojan horse for the pharmaceutical industry, a new study says.

AAO: Sequential nonarteritic anterior ischemic optic neuropathy occurs earlier with GLP-1 receptor agonist exposure

https://medicalxpress.com/news/2026-10-aao-sequential-nonarteritic-anterior-ischemic.html

Published: October 21, 2026 20:20

For patients with nonarteritic anterior ischemic optic neuropathy (NAION), glucagon-like peptide-1 (GLP-1) receptor agonist exposure is associated with earlier sequential NAION, according to a study presented at the annual meeting of the American Academy…

AAO: Association between GLP-1 receptor agonists and age-related macular degeneration explored

https://medicalxpress.com/news/2026-10-aao-association-glp-receptor-agonists.html

Published: October 21, 2026 16:20

Crude odds ratios suggest an increased risk for age-related macular degeneration (AMD) in association with glucagon-like peptide-1 receptor agonist (GLP-1 RA) use, but this finding is reversed after adjustment for cardiometabolic confounding variables,…

Newer anticoagulants may help prevent strokes in AFib patients with previous brain bleeds

https://medicalxpress.com/news/2026-10-anticoagulants-afib-patients-previous-brain.html

Published: October 21, 2026 16:00

For people with atrial fibrillation (AFib), an irregular heartbeat, and intracranial hemorrhage, a type of stroke also known as a brain bleed, anticoagulant use was associated with a lower risk of ischemic stroke and death, according to a new study…

Existing cancer drug reduces blood vessel malformations in the brain

https://medicalxpress.com/news/2026-10-cancer-drug-blood-vessel-malformations.html

Published: October 21, 2026 14:00

Researchers have identified a substance that reduces blood vessel lesions in the brain in the disease cerebral cavernous malformation (CCM). The substance is already used to treat brain tumors in children and could therefore be repurposed relatively…

Started a GLP‑1 drug like Ozempic or Mounjaro? Here's what you need to know about nutrition

https://medicalxpress.com/news/2026-10-glp1-drug-ozempic-mounjaro-nutrition.html

Published: October 21, 2026 12:00

Around half a million Australians use GLP-1 medications for diabetes—and when you add people who use them for obesity and weight-related conditions, the total is much higher.

The hidden role of a cancer treatment target could explain toxic side effects

https://medicalxpress.com/news/2026-10-hidden-role-cancer-treatment-toxic.html

Published: October 21, 2026 11:00

Wee1 inhibitors are a promising new cancer treatment, but serious side effects threaten their adoption in the clinic. Now, researchers from the MRC Laboratory of Medical Sciences (LMS), the University of Oxford and UCL have discovered a previously unknown…

Would subsidizing weight-loss drugs make health care fairer?

https://medicalxpress.com/news/2026-10-subsidizing-weight-loss-drugs-health.html

Published: October 20, 2026 20:40

GLP-1 medicines such as Ozempic, Wegovy and Mounjaro have transformed the treatment of obesity, but access to them in Australia increasingly depends on something much less medical: whether you can afford them.

Low vitamin D use in patients on enzyme-inducing antiseizure drugs raises concerns

https://medicalxpress.com/news/2026-10-vitamin-d-patients-enzyme-antiseizure.html

Published: October 20, 2026 16:50

Enzyme-inducing antiseizure drugs (ASDs) are associated with increased odds of incident osteoporosis or osteopenia, but vitamin D supplementation is underutilized, according to a study presented at the annual meeting of the American Neurological…

Nutritional supplement may help ease 'brain fog' after breast cancer treatment

https://medicalxpress.com/news/2026-10-nutritional-supplement-ease-brain-fog.html

Published: October 20, 2026 16:00

A new study led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center found that a nutritional supplement containing oxaloacetate, a molecule naturally found in the body that helps cells produce energy, may help improve cognitive function…

'Smart bomb' combination attacks triple-negative breast cancer in preclinical study

https://medicalxpress.com/news/2026-10-smart-combination-triple-negative-breast.html

Published: October 20, 2026 13:00

A new preclinical study suggests that attacking triple-negative breast cancer (TNBC) in two ways at once can kill cancer cells, slow tumor growth and limit the cancer's spread. Researchers at The Ohio State University Comprehensive Cancer Center—Arthur G.…

Cannabis is getting stronger, but doubling THC dose doesn't get you twice as 'high'—new study

https://medicalxpress.com/news/2026-10-cannabis-stronger-thc-dose-doesnt.html

Published: October 20, 2026 12:40

Cannabis products are getting more potent and easier to buy around the world. Yet little is known about how bigger doses of tetrahydrocannabinol (THC), the main active ingredient in cannabis, change what people feel. Our new research found that larger…

Cranking up a natural defense pathway boosts cells' resistance to RSV

https://medicalxpress.com/news/2026-10-cranking-natural-defense-pathway-boosts.html

Published: October 20, 2026 12:40

Washington State University researchers have discovered how to "crank up" a natural defense system in the body to combat viral infection, potentially opening a new door for treating virus infections, cancer, neurological disorders and other diseases.

Search for Alzheimer's drug unexpectedly finds possible biomarker

https://medicalxpress.com/news/2026-10-alzheimer-drug-unexpectedly-biomarker.html

Published: October 20, 2026 12:20

Researchers developed a drug for Alzheimer's disease and then discovered that the molecule already exists in human blood and is found at lower levels in cognitively impaired people. Now the authors are exploring the peptide as a biomarker as well as a…

Testosterone therapy may increase risk of cardiovascular disease in postmenopausal women

https://medicalxpress.com/news/2026-10-testosterone-therapy-cardiovascular-disease-postmenopausal.html

Published: October 20, 2026 12:00

Testosterone therapy is not routinely recommended for postmenopausal women, in part because long-term safety data remain limited. It is, however, prescribed off label to help women suffering from low libido. A new study links testosterone therapy in…

Q&A: Why does your prescription cost so much?

https://medicalxpress.com/news/2026-10-qa-prescription.html

Published: October 20, 2026 11:40

You've probably had the experience of going to the pharmacy to pick up a medication and being surprised by how much it costs.

Combined estrogen and testosterone therapy increases lumbar spine bone mineral density

https://medicalxpress.com/news/2026-10-combined-estrogen-testosterone-therapy-lumbar.html

Published: October 20, 2026 11:20

Bone mineral density significantly decreases during and after menopause due to dropping levels of estrogen. Historically, estrogen therapy has been prescribed to help protect bones, but a new study suggests that the addition of testosterone therapy may…

Hormone therapy may increase weight-loss effectiveness of GLP-1s

https://medicalxpress.com/news/2026-10-hormone-therapy-weight-loss-effectiveness.html

Published: October 20, 2026 08:20

The success stories of GLP-1 weight-loss medications are dominating the airwaves. Midlife women, who commonly experience weight gain resulting from menopause, have been especially drawn to the drugs.

GLP-1 drugs linked to lower kidney failure risk in bipolar disorder

https://medicalxpress.com/news/2026-10-glp-drugs-linked-kidney-failure.html

Published: October 19, 2026 15:40

Mayo Clinic researchers found that GLP-1 receptor agonists, medications widely used for diabetes and weight management, were associated with a lower risk of dialysis or kidney transplantation in adults with bipolar disorder and chronic kidney disease.

Second-ever case of rare fungus resistant to four antifungal drug classes detected in Kenya

https://medicalxpress.com/news/2026-10-case-rare-fungus-resistant-antifungal.html

Published: October 19, 2026 09:20

While a mutant fungus in the real world might not be making humans violent and turning them against each other as in the fictional world of "The Last of Us," it is raising alarm bells for public health.

Common painkiller may not be to blame for blood clots in women on the pill

https://medicalxpress.com/news/2026-10-common-painkiller-blame-blood-clots.html

Published: October 19, 2026 09:00

The higher risk of blood clots (venous thromboembolism, VTE) seen in women who use nonsteroidal anti-inflammatory drugs (NSAIDs) with hormonal contraceptives (HCs) is likely due to the health problem for which the painkillers are taken, rather than the…

Millions of older Australians exposed to overlapping medication risks

https://medicalxpress.com/news/2026-10-millions-older-australians-exposed-overlapping.html

Published: October 19, 2026 07:20

An estimated 2.3 million older Australians are being dispensed multiple medicines associated with falls and fractures, while more than 1.2 million are receiving combinations linked to kidney-related side effects, according to new research from Adelaide…

Melatonin and Ambien before surgery may improve sleep, reduce pain and opioid use after surgery

https://medicalxpress.com/news/2026-10-melatonin-ambien-surgery-pain-opioid.html

Published: October 18, 2026 17:50

Improving sleep before surgery through the use of melatonin or Ambien (zolpidem) may ease presurgical anxiety, reduce pain after surgery, decrease opioid requirements and help patients recover better, according to an analysis of 25 years of research…

Lab-designed molecule reduces amyloid beta, the protein linked to Alzheimer's disease, in mice

https://medicalxpress.com/news/2026-10-lab-molecule-amyloid-beta-protein.html

Published: October 17, 2026 10:40

A research team led by the Molecular and Cellular Neurobiotechnology group at the Institute for Bioengineering of Catalonia (IBEC), in collaboration with Míriam Royo's laboratory at the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), the…

New drug-delivery method offers promise in fight against neurodegenerative diseases

https://medicalxpress.com/news/2026-10-drug-delivery-method-neurodegenerative-diseases.html

Published: October 16, 2026 14:20

For patients battling neurodegenerative diseases like ALS, Parkinson's, Alzheimer's and other dementias, delivering disease-fighting antibody drugs directly to the brain has proven to be a difficult task. Our bodies set up tight walls to prevent infections…

Head-to-head comparison of three mRNA vaccines reveals differences in their stability in human blood

https://medicalxpress.com/news/2026-10-comparison-mrna-vaccines-reveals-differences.html

Published: October 16, 2026 13:40

A study by Australian researchers compared three mRNA-LNP vaccine platforms in human blood samples, generating findings that could advance cancer treatment and vaccine design.

The receptor behind chili-pepper burn may hold clues to pain treatments

https://medicalxpress.com/news/2026-10-receptor-chili-pepper-clues-pain.html

Published: October 16, 2026 11:40

Scientists have long known that capsaicin, the ingredient that makes chili peppers feel hot and is used in some pain-relief creams, works by activating a pain-sensing receptor known as TRPV1.