RSS Parrot

Semaglutide linked to lower bone fracture risk

https://medicalxpress.com/news/2026-06-semaglutide-linked-bone-fracture.html

Published: June 14, 2026 14:50

In people with type 2 diabetes, semaglutide was associated with a 15% reduction in bone fractures and greater weight loss compared with other anti-obesity medications, according to a study presented at ENDO 2026, the Endocrine Society's annual meeting in…

Inflation Reduction Act's out-of-pocket cap lowered insulin costs, improved usage for some patients

https://medicalxpress.com/news/2026-06-inflation-reduction-pocket-cap-lowered.html

Published: June 14, 2026 10:30

The Inflation Reduction Act's attempt to improve insulin costs for Medicare beneficiaries—by capping out-of-pocket costs at $35—was associated with lower out-of-pocket costs and increased insulin use, but only for a small portion of U.S. patients,…

Study finds exercise decreases among people taking GLP-1 medication

https://medicalxpress.com/news/2026-06-decreases-people-glp-medication.html

Published: June 13, 2026 18:40

Adults with obesity who lost weight with glucagon-like peptide-1 (GLP-1) receptor agonist medications significantly decreased their physical activity, which is essential to protect muscle, according to a study presented at ENDO 2026, the Endocrine…

Adding genetic data to steroid prescribing can help predict side effects, data suggest

https://medicalxpress.com/news/2026-06-adding-genetic-steroid-side-effects.html

Published: June 13, 2026 18:00

Oral corticosteroids (OCSs) are widely used and effective in the treatment of chronic inflammatory conditions such as arthritis, asthma and autoimmune diseases. They work by reducing inflammation, relieving pain and calming the immune system. However, more…

Glucosamine supplements may speed memory loss from Alzheimer's, new research shows

https://medicalxpress.com/news/2026-06-glucosamine-supplements-memory-loss-alzheimer.html

Published: June 13, 2026 15:30

People with Alzheimer's disease who took the common supplement glucosamine were 25% more likely to die within five years than those who didn't. That's the key finding of a new study that my colleagues and I published in the journal Nature Metabolism.

Key mechanism regulating the anti-inflammatory function of extracellular vesicles identified

https://medicalxpress.com/news/2026-06-key-mechanism-anti-inflammatory-function.html

Published: June 13, 2026 11:00

A study led by the Innovation in Vesicles and Cells for Application in Therapy (IVECAT) group at the Germans Trias i Pujol Research Institute (IGTP) has identified a key mechanism regulating the anti-inflammatory function of extracellular vesicles derived…

ADA: Once-weekly cagrilintide + semaglutide promising in type 2 diabetes

https://medicalxpress.com/news/2026-06-ada-weekly-cagrilintide-semaglutide-diabetes.html

Published: June 12, 2026 14:20

Once-weekly cagrilintide, an amylin receptor agonist, plus semaglutide is efficacious for adults with type 2 diabetes inadequately controlled with diet and exercise, receiving metformin with or without a sodium glucose cotransporter 2 inhibitor (SGLT2i),…

Metal-free carbon monoxide prodrugs may help prevent cancer's deadly spread

https://medicalxpress.com/news/2026-06-metal-free-carbon-monoxide-prodrugs.html

Published: June 12, 2026 12:40

A carefully designed metal-free carbon monoxide prodrug—an inactive compound that is converted into its active form in the body—may help prevent some of the deadliest forms of cancer from spreading, according to researchers at Weill Cornell Medicine. Their…

Shorter clinical trials of medication for alcohol use disorder can be as useful or more useful than longer trials

https://medicalxpress.com/news/2026-06-shorter-clinical-trials-medication-alcohol.html

Published: June 12, 2026 12:20

Randomized control trials that are shorter than 12 weeks show similar results to longer trials when assessing a new medication's effectiveness in helping someone with alcohol use disorder reduce or stop drinking. And in trials where the medication showed…

Scientists track single-dose vaccines for Andes hantavirus strain

https://medicalxpress.com/news/2026-06-scientists-track-dose-vaccines-andes.html

Published: June 12, 2026 07:20

In a study published in The Lancet, researchers at The University of Texas Medical Branch (UTMB) report the development of new vaccines that, in animal testing, provided full protection against the deadly Andes hantavirus after a single dose.

A fentanyl countermeasure that adapts to combat future black-market drugs

https://medicalxpress.com/news/2026-06-fentanyl-countermeasure-combat-future-black.html

Published: June 12, 2026 07:00

Fentanyl and related variants of the synthetic opioid kill more Americans each year than car accidents and gun violence combined. In too-high doses, the drugs hijack brain chemistry and shut down the signals that control breathing. Existing medical…

Engineers find a way to deliver drugs directly to the esophagus

https://medicalxpress.com/news/2026-06-drugs-esophagus.html

Published: June 12, 2026 05:00

There are few treatment options available for people with disorders of the esophagus. Delivering drugs directly to this part of the body is difficult, so patients are usually treated with systemic drugs, which can have unwanted side effects.

Popular joint pain supplement might increase Alzheimer's risk, study says

https://medicalxpress.com/news/2026-06-popular-joint-pain-supplement-alzheimer.html

Published: June 11, 2026 22:40

A popular over-the-counter supplement taken for joint pain might increase people's risk for Alzheimer's disease, a new study says.

Cancer drug combo activates inflammatory signal that could boost immune response

https://medicalxpress.com/news/2026-06-cancer-drug-combo-inflammatory-boost.html

Published: June 11, 2026 13:20

What if a new combination of cancer drugs could sound an alarm, alerting the body's immune system to invoke a targeted response to cancer cells? Findings from a new study appear in a paper published in Nucleic Acids Research.

New study shows metformin given during acute COVID-19 infection reduced risk of clinician-diagnosed long COVID by 50%

https://medicalxpress.com/news/2026-06-metformin-acute-covid-infection-clinician.html

Published: June 11, 2026 13:00

New findings from the ACTIV-6 randomized clinical trial provide important confirmation of prior clinical trial results that metformin, a widely available and inexpensive medication with an established safety record, reduced the risk of clinician-diagnosed…

IV atorvastatin during myocardial infarction reduces myocardial damage compared to pre-infarction oral loading

https://medicalxpress.com/news/2026-06-iv-atorvastatin-myocardial-infarction-pre.html

Published: June 10, 2026 21:40

Reducing the damage sustained by the heart during a myocardial infarction remains one of the major challenges in cardiology, even when the blocked coronary artery is reopened in a timely manner. Part of the myocardial injury continues to be difficult to…

Once-weekly survodutide linked to drop in body weight in obesity

https://medicalxpress.com/news/2026-06-weekly-survodutide-linked-body-weight.html

Published: June 10, 2026 19:40

For adults with obesity without diabetes, once-weekly survodutide, an investigational glucagon receptor-glucagon-like peptide-1 receptor dual agonist, is associated with greater reductions in body weight than placebo, according to a study published online…

Why the liquid you take with your medication matters

https://medicalxpress.com/news/2026-06-liquid-medication.html

Published: June 10, 2026 18:00

Some alkaline mineral and medicinal waters may weaken the enteric coating of medications within just a few minutes, potentially reducing their effectiveness, according to a new study by Semmelweis University. The study, published in Pharmaceutics, found…

Girls are biggest consumers of anxiolytic and sedative drugs among adolescents in most EU countries

https://medicalxpress.com/news/2026-06-girls-biggest-consumers-anxiolytic-sedative.html

Published: June 10, 2026 17:40

Xabi Martinez-Mendia, a researcher at the EHU-University of the Basque Country, has analyzed how adolescent psychotropic drug consumption is linked to gender inequality and economic factors in 32 European countries. Published in the European Journal of…

Drug reduces the risk of developing rheumatoid arthritis, clinical trial finds

https://medicalxpress.com/news/2026-06-drug-rheumatoid-arthritis-clinical-trial.html

Published: June 10, 2026 17:20

A clinical trial led by researchers from Hospital Clínic de Barcelona, the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) and the Institute of Advanced Chemistry of Catalonia (IQAC-CSIC) compared the effectiveness of abatacept and…

How modern rheumatoid arthritis treatments can protect bone health

https://medicalxpress.com/news/2026-06-modern-rheumatoid-arthritis-treatments-bone.html

Published: June 10, 2026 17:10

A new review published in Calcified Tissue International highlights major advances in understanding and preventing bone loss in people with rheumatoid arthritis (RA), showing that modern antirheumatic therapies can significantly reduce local and…

New protein targets reveal 13 drug repurposing leads for progressive multiple sclerosis

https://medicalxpress.com/news/2026-06-protein-reveal-drug-repurposing-multiple.html

Published: June 10, 2026 16:40

A new study identified protein targets and drug candidates, including opportunities to repurpose existing drugs. Six key proteins were highlighted as potentially providing new insights and supporting future treatment development for progressive multiple…

'Molecular eraser' destroys cancerous mRNA before protein forms, reshaping cancer cells

https://medicalxpress.com/news/2026-06-molecular-eraser-destroys-cancerous-mrna.html

Published: June 10, 2026 14:40

Many of the deadliest forms of cancer are caused by a pathological mutation in the RAS protein. Yet, to date, no effective treatment for this cancer protein has been found. A new research approach aims to prevent the protein from forming in the first place…

Key protein behind chemotherapy resistance in colorectal cancer identified

https://medicalxpress.com/news/2026-06-key-protein-chemotherapy-resistance-colorectal.html

Published: June 9, 2026 21:40

One of the most widely used chemotherapeutic agents for colorectal cancer is 5-fluorouracil (5-FU), a cornerstone treatment that has improved outcomes for countless patients. However, repeated treatment often leads to drug resistance, allowing cancer cells…

Drug apitegromab may stop muscle loss when taking weight loss drugs

https://medicalxpress.com/news/2026-06-drug-apitegromab-muscle-loss-weight.html

Published: June 9, 2026 14:00

A drug called apitegromab may help preserve lean body mass during weight loss with tirzepatide, a GLP-1 receptor agonist, according to a phase 2 clinical trial published in Nature Medicine. The findings suggest that blocking a protein that limits muscle…

Physician–researcher's work yields landmark five-year data for Crohn's disease drug

https://medicalxpress.com/news/2026-06-physicianresearcher-yields-landmark-year-crohn.html

Published: June 9, 2026 12:20

A physician–scientist and national leader in inflammatory bowel disease at the University of Cincinnati has led the publication of landmark five-year efficacy and safety data for guselkumab, a biologic therapy for moderately to severely active Crohn's…

Medication burden and weight loss linked to fracture, fall risk in older adults

https://medicalxpress.com/news/2026-06-medication-burden-weight-loss-linked.html

Published: June 9, 2026 11:20

With an aging population now an irrefutable reality in Japan, concerns about the health and well-being of older adults have come to the forefront of public health dialogue. Older adults are especially at risk for fragility fractures and falls, which…

Tiny molecular fix revived tuberculosis antibiotic candidate and led to two patents

https://medicalxpress.com/news/2026-06-tiny-molecular-revived-tuberculosis-antibiotic.html

Published: June 9, 2026 11:00

How can we combat the growing global health crisis of antibiotic resistance? At Leiden University, researchers are tackling this issue from multiple angles. Ph.D. candidate Vladyslav Lysenko develops and redesigns new antibiotic molecules, while Sebastian…

New GLP-3 drug significantly slashes both weight and blood sugar levels in Phase III trial

https://medicalxpress.com/news/2026-06-glp-drug-significantly-slashes-weight.html

Published: June 9, 2026 10:40

Over the past few years, GLP-1 drugs have transformed the treatment landscape for obesity and type 2 diabetes. By mimicking a hormone that helps regulate blood sugar, slows digestion and curbs appetite, these medications have helped millions lose weight…

Single high dose of psilocybin temporarily restores lost abilities in an 80-year-old Alzheimer's patient

https://medicalxpress.com/news/2026-06-high-dose-psilocybin-temporarily-lost.html

Published: June 9, 2026 07:20

Psilocybin is a naturally occurring psychoactive compound found in mushrooms of the Psilocybe genus. These mushrooms may have existed on Earth for nearly 65 million years, dating to the asteroid impact that caused the dinosaurs' extinction. While…

A popular joint pain supplement may accelerate dementia

https://medicalxpress.com/news/2026-06-popular-joint-pain-supplement-dementia.html

Published: June 9, 2026 05:00

New research has found an association between taking glucosamine, a popular over-the-counter supplement used for joint pain, and a higher likelihood of progressing from mild cognitive impairment to Alzheimer's disease. The finding by University of Florida…

New Lassa fever vaccine shows promising results for first-in-human clinical trial

https://medicalxpress.com/news/2026-06-lassa-fever-vaccine-results-human.html

Published: June 9, 2026 05:00

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health, or CVD, report encouraging results from an early clinical trial that tested a new dual vaccine against Lassa fever and rabies. The study,…

Encouraging trial results for AstraZeneca's new weight-loss pill

https://medicalxpress.com/news/2026-06-trial-results-astrazeneca-weight-loss.html

Published: June 9, 2026 05:00

A new pill developed by the British pharmaceutical firm AstraZeneca appears to help people lose a similar amount of weight as other oral GLP-1 drugs, trial results showed Monday.

Nanoparticles target psoriasis genes, aiming to treat 190 million people worldwide

https://medicalxpress.com/news/2026-06-nanoparticles-psoriasis-genes-aiming-million.html

Published: June 8, 2026 19:40

A technological platform developed by Brazilian researchers could revolutionize the treatment of skin diseases such as psoriasis and vitiligo. The group, affiliated with the NanoGeneSkin laboratory at the University of São Paulo (USP) in Ribeirão Preto, is…

The hunt for a new Ebola vaccine: Two scientists explain the challenges

https://medicalxpress.com/news/2026-06-ebola-vaccine-scientists.html

Published: June 8, 2026 18:40

The ongoing Ebola virus outbreak in the Democratic Republic of Congo (DRC) and Uganda has now killed 61 people, with 359 confirmed cases. The Bundibugyo strain of the virus has a fatality rate of between 30% and 50%, and there is currently no vaccine…

Target trial does not suggest major adverse outcomes with early GLP-1 use in pregnancy

https://medicalxpress.com/news/2026-06-trial-major-adverse-outcomes-early.html

Published: June 8, 2026 17:00

A target trial emulation estimated the risks associated with glucagon-like peptide-1 receptor agonist (GLP-1RA) exposure in early pregnancy. The findings did not indicate a substantially increased risk for nonlive birth, abnormal fetal growth, or major…

Left-handed DNA tubes double cancer drug killing by boosting cell uptake

https://medicalxpress.com/news/2026-06-left-dna-tubes-cancer-drug.html

Published: June 8, 2026 16:40

Researchers in the lab of Cancer Center at Illinois (CCIL) member Xing Wang have discovered the influential role of structural chirality, or "handedness," of a DNA nanostructure to dictate cancer cell response to targeted therapeutics. The team's findings…

New GLP-1 oral pill lowers blood sugar and reduces bodyweight, clinical trial finds

https://medicalxpress.com/news/2026-06-glp-oral-pill-lowers-blood.html

Published: June 8, 2026 16:20

Oral GLP-1 medications have the potential to increase access to therapies that can help lower blood sugar and reduce bodyweight. At the American Diabetes Association's Scientific Session, Mass General Brigham physician investigator Vanita Aroda, MD,…

New drug could slow the development of Alzheimer's

https://medicalxpress.com/news/2026-06-drug-alzheimer.html

Published: June 8, 2026 16:00

"Compound 10" is how Ursula Quitterer refers to the chemical compound that her team has developed and that could slow the progression of Alzheimer's disease. Quitterer is a professor of molecular pharmacology at ETH Zurich and has so far tested the active…

Ultrasound turns anticancer molecule into deep-lung bacteria killer

https://medicalxpress.com/news/2026-06-ultrasound-anticancer-molecule-deep-lung.html

Published: June 8, 2026 14:00

An anticancer medication called TLD1433, a ruthenium(II) complex that has entered Phase II trials for conditions such as non-muscle-invasive bladder cancer, is now being repurposed to address one of the biggest public health issues globally—bacterial…

Hay fever, antihistamines and the evidence on dementia risk

https://medicalxpress.com/news/2026-06-hay-fever-antihistamines-evidence-dementia.html

Published: June 8, 2026 14:00

For millions of people around the world, pollen season means weeks of sneezing, itchy eyes, and a blocked or runny nose. The timing varies depending on where you live and which plants are in flower, but grass pollen is one of the most common triggers.

New map reveals how antidepressants reshape the brain's serotonin system

https://medicalxpress.com/news/2026-06-reveals-antidepressants-reshape-brain-serotonin.html

Published: June 8, 2026 12:40

A new study has uncovered how antidepressants affect different groups of serotonin-producing brain cells in opposite ways, offering new insights into why selective serotonin reuptake inhibitors (SSRIs) can cause unpleasant side effects at the start of…

Africa races for Ebola vaccine as outbreak outpaces response

https://medicalxpress.com/news/2026-06-africa-ebola-vaccine-outbreak-outpaces.html

Published: June 8, 2026 12:00

Researchers racing to develop a vaccine to fight the growing Ebola outbreak centered in the Democratic Republic of the Congo (DRC) say doses could be ready for human testing within "two to three months," while the more promising candidate could take up to…

Ozempic, GPL-1s may help curb substance use disorders, study finds

https://medicalxpress.com/news/2026-06-ozempic-gpl-1s-curb-substance.html

Published: June 8, 2026 10:40

A new study led by researchers at the University of Texas at El Paso found that use of weight-loss drugs like Ozempic and other GLP-1s is associated with a lower risk of developing alcohol, opioid, nicotine and cocaine use disorders.