RSS Parrot

Ivarmacitinib 4 mg, 8 mg efficacious for adults with severe alopecia areata

https://medicalxpress.com/news/2025-03-ivarmacitinib-mg-efficacious-adults-severe.html

Published: March 13, 2025 13:50

For adults with severe alopecia areata (AA), ivarmacitinib, a selective Janus kinase 1 (JAK1) inhibitor, at doses of 4 and 8 mg is efficacious and tolerable, according to a study presented at the annual meeting of the American Academy of Dermatology, held…

Three-quarters of people who have taken antidepressants say they were helpful

https://medicalxpress.com/news/2025-03-quarters-people-antidepressants.html

Published: March 13, 2025 13:39

In a sample of nearly 20,000 people who have taken selective serotonin reuptake inhibitors (SSRIs), 75% report they found them helpful, finds new research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London.

World-first clinical trial shows promise for transformative oral snakebite treatment

https://medicalxpress.com/news/2025-03-world-clinical-trial-oral-snakebite.html

Published: March 13, 2025 11:27

Researchers from Liverpool School of Tropical Medicine (LSTM) have completed a Phase I clinical trial for a new oral treatment for snakebite.

Diterpene-based drug achieves functional neuronal regeneration after brain injury in preclinical study

https://medicalxpress.com/news/2025-03-diterpene-based-drug-functional-neuronal.html

Published: March 13, 2025 09:18

Researchers from the University of Seville and the University of Cadiz, coordinated by the professors of Physiology Pedro Núñez-Abades and Carmen Castro, have demonstrated that the use of diterpenes facilitates repopulation with new neurons in brain…

Improving rehabilitation after spinal cord injury using a small compound oral drug

https://medicalxpress.com/news/2025-03-spinal-cord-injury-small-compound.html

Published: March 13, 2025 08:20

Spinal cord injury (SCI)—a condition that leads to partial or complete paralysis—has a profound impact on millions of individuals globally. Despite recent advances in SCI treatment, restoring lost motor functions, such as hand movement, remains a…

Newly approved clot-busting drug works as well as traditional drug for stroke, research shows

https://medicalxpress.com/news/2025-03-newly-clot-drug-traditional.html

Published: March 13, 2025 08:07

A clot-busting drug recently approved to treat acute ischemic strokes (AIS) that can be delivered quickly works as well as a decades-old medication used by most hospitals in the U.S. and could hold significant advantages for some patients, a study led by a…

Scientists are on track to find a treatment for autoimmune hair loss

https://medicalxpress.com/news/2025-03-scientists-track-treatment-autoimmune-hair.html

Published: March 13, 2025 06:00

A research group, led by Dr. Pavel Majer from IOCB Prague, in collaboration with the laboratories of Barbara Slusher and Louis Garza at Johns Hopkins University, has developed a compound that could potentially treat the autoimmune disorder alopecia areata,…

Cannabis terpenes offer potential new way to treat fibromyalgia pain

https://medicalxpress.com/news/2025-03-cannabis-terpenes-potential-fibromyalgia-pain.html

Published: March 12, 2025 15:53

Terpenes from the Cannabis sativa plant may be a viable medication for fibromyalgia and post-surgical pain relief, according to University of Arizona Health Sciences research published in Pharmacological Reports.

Monoclonal antibody significantly reduces nasal polyps and need for surgery in Phase 3 clinical trial

https://medicalxpress.com/news/2025-03-monoclonal-antibody-significantly-nasal-polyps.html

Published: March 12, 2025 15:10

Chronic rhinosinusitis with nasal polyps presents a substantial clinical burden, affecting nasal airflow, olfactory function, and quality of life. Epithelial barrier dysfunction and type 2 inflammatory responses drive disease progression. Treatments such…

Tecovirimat is safe but ineffective as treatment for clade II mpox

https://medicalxpress.com/news/2025-03-tecovirimat-safe-ineffective-treatment-clade.html

Published: March 12, 2025 13:15

The antiviral drug tecovirimat used without other antivirals did not reduce the time to clinical resolution of clade II mpox lesions or improve pain control among adults in an international clinical trial sponsored by the National Institutes of Health…

Drug may prevent COVID-19 in exposed people within households, major trial finds

https://medicalxpress.com/news/2025-03-drug-covid-exposed-people-households.html

Published: March 12, 2025 13:08

An international clinical trial has identified a medication that can help prevent symptomatic COVID-19 in people exposed within households. The results could be particularly important for families where someone is at high risk of serious complications from…

Reformulation of HIV prevention drug lenacapavir makes it last for a year

https://medicalxpress.com/news/2025-03-reformulation-hiv-drug-lenacapavir-year.html

Published: March 12, 2025 12:20

A team of pharmaceutical researchers at biopharma company Gilead Sciences has announced that a reformulation of its HIV prevention drug lenacapavir allows it to persist in the body for up to a year. In their paper published in The Lancet journal, the group…

Pharmacies in England may be twice as likely to supply antibiotics for sore throat than in Wales

https://medicalxpress.com/news/2025-03-pharmacies-england-antibiotics-sore-throat.html

Published: March 12, 2025 11:17

Patients with a sore throat are more than twice as likely to be given antibiotics by a pharmacist through England's Pharmacy First Scheme compared with a similar scheme in Wales, according to an initial analysis published in the Journal of Antimicrobial…

Study finds yearly 18% rise in ADHD prescriptions in England since COVID-19 pandemic

https://medicalxpress.com/news/2025-03-yearly-adhd-prescriptions-england-covid.html

Published: March 11, 2025 18:30

Prescriptions for attention deficit hyperactivity disorder (ADHD) in England have risen 18% year on year since the pandemic. This is higher than previously reported, and masks wide regional variations in prescribing rates, finds research published in the…

Stopping GLP-1 RAs 14 days before surgery can minimize complications

https://medicalxpress.com/news/2025-03-glp-ras-days-surgery-minimize.html

Published: March 11, 2025 16:50

Stopping glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment 14 days before total joint arthroplasty can minimize risks for complications, according to a study presented at the annual meeting of the American Academy of Orthopaedic Surgeons, held…

Remibrutinib beneficial for urticaria after H1-antihistamine treatment

https://medicalxpress.com/news/2025-03-remibrutinib-beneficial-urticaria-h1-antihistamine.html

Published: March 11, 2025 13:40

For patients with symptomatic chronic spontaneous urticaria after treatment with second-generation H1-antihistamines, administration of the oral, highly selective Bruton's tyrosine kinase inhibitor, remibrutinib, results in a significant improvement in a…

Compound found in common herbs inspires potential anti-inflammatory drug for Alzheimer's disease

https://medicalxpress.com/news/2025-03-compound-common-herbs-potential-anti.html

Published: March 10, 2025 15:14

The herb rosemary has long been linked with memory. "There's rosemary, that's for remembrance," says Ophelia in Shakespeare's "Hamlet." So it is fitting that researchers would study a compound found in rosemary and sage—carnosic acid—for its impact on…

Upper urinary tract cancer drug may offer long-term benefits

https://medicalxpress.com/news/2025-03-upper-urinary-tract-cancer-drug.html

Published: March 10, 2025 13:20

While randomized comparative trials are needed, a relatively new treatment option for upper urinary tract cancers shows promise for lowering long-term recurrence in many patients with low-grade disease, according to a multicenter study led by researchers…

Ammonia buildup kills liver cells but can be prevented using existing drug

https://medicalxpress.com/news/2025-03-ammonia-buildup-liver-cells-drug.html

Published: March 7, 2025 14:00

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice led by researchers from UCL.

Experimental drug found to more than double survival time for glioblastoma patients

https://medicalxpress.com/news/2025-03-experimental-drug-survival-glioblastoma-patients.html

Published: March 7, 2025 09:48

A drug developed at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has been shown to extend survival for patients with glioblastoma, the most common primary brain tumor in adults.

FDA approves TNKase for acute ischemic stroke

https://medicalxpress.com/news/2025-03-fda-tnkase-acute-ischemic.html

Published: March 6, 2025 17:09

The U.S. Food and Drug Administration has approved TNKase (tenecteplase), a thrombolytic or clot-dissolving agent, for the treatment of acute ischemic stroke in adults.

No link seen between preop GLP-1 receptor agonist use and postop aspiration pneumonia

https://medicalxpress.com/news/2025-03-link-preop-glp-receptor-agonist.html

Published: March 6, 2025 13:58

Preoperative glucagon-like peptide-1 receptor agonist (GLP-1 RA) use is not associated with short-term postoperative aspiration pneumonia, according to a study published online March 4 in JAMA Network Open.

Long-acting injectable HIV therapy offers hope for those unable to take pills

https://medicalxpress.com/news/2025-03-hiv-therapy-unable-pills.html

Published: March 6, 2025 11:00

Patients who struggle to take daily HIV pills can benefit from long-acting injectable treatments, a new study by researchers at UCSF has found.

Robert F. Kennedy Jr says vitamin A protects you from deadly measles. Here's what the study he cites actually says

https://medicalxpress.com/news/2025-03-robert-kennedy-jr-vitamin-deadly.html

Published: March 6, 2025 10:56

Robert F. Kennedy Jr, who oversees the health of more than 340 million Americans, says vitamin A can prevent the worst effects of measles rather than urging more people to get vaccinated.

Over-the-counter pain relievers linked to improved recovery from concussion

https://medicalxpress.com/news/2025-03-counter-pain-relievers-linked-recovery.html

Published: March 5, 2025 16:24

People who take over-the-counter pain relievers after a concussion may recover faster than those who do not take pain relievers, according to a preliminary study released today, March 5, 2025, that will be presented at the American Academy of Neurology's…

A 'Trojan horse' approach may enable development of new antimalarial drugs

https://medicalxpress.com/news/2025-03-trojan-horse-approach-enable-antimalarial.html

Published: March 5, 2025 16:10

Antimalarial drug resistance is a pressing issue in combating the spread of malaria worldwide. In a new study, researchers from Children's Hospital of Philadelphia (CHOP) have discovered a key process where malarial parasites take up a human blood cell…

Obtaining ADHD drugs via telehealth could increase addiction risk

https://medicalxpress.com/news/2025-03-adhd-drugs-telehealth-addiction.html

Published: March 5, 2025 14:50

For nearly five years, people with attention deficit/hyperactivity disorder have had the option of getting their stimulant medications prescribed and renewed by doctors they see only over a computer screen, despite the risks that these stimulant drugs can…

Combination of approved drugs offers new strategies for acute myeloid leukemia

https://medicalxpress.com/news/2025-03-combination-drugs-strategies-acute-myeloid.html

Published: March 5, 2025 11:16

The combined use of two well-known active substances can fight leukemic cells and limit their spread. This is the result of a study conducted by the Karl Landsteiner University of Health Sciences (KL Krems) and published in the journal Cancer Letters.

New study to inform Australia's first psychedelics clinical guideline

https://medicalxpress.com/news/2025-03-australia-psychedelics-clinical-guideline.html

Published: March 5, 2025 10:06

Australia's first clinical practice guideline on the appropriate use of methylenedioxymethamphetamine-assisted psychotherapy (MDMA-AP) to treat post-traumatic stress disorder (PTSD) is a step closer following the publication of a new Monash-led study.

Gut-liver modulator shows promising type 2 diabetes control in phase 2 clinical trial

https://medicalxpress.com/news/2025-03-gut-liver-modulator-diabetes-phase.html

Published: March 5, 2025 08:00

Researchers across 14 medical centers in China, including Peking University People's Hospital, have found that an investigational drug, berberine ursodeoxycholate (HTD1801), significantly lowered blood sugar levels and improved metabolic and liver health…

Study shows that long-term NSAID use is linked to a decreased risk of developing dementia

https://medicalxpress.com/news/2025-03-term-nsaid-linked-decreased-dementia.html

Published: March 5, 2025 03:10

Past research has suggested that inflammation may contribute to the development and progression of dementia and that non-steroidal anti-inflammatory (NSAID) medications may help protect against dementia due to their anti-inflammatory effects. A new large…

New knowledge may help make medicines taste better for the most bitter-sensitive

https://medicalxpress.com/news/2025-03-knowledge-medicines-bitter-sensitive.html

Published: March 4, 2025 17:04

Many medicines taste so bitter that some people avoid taking them. To help with the bad taste, flavors and sweeteners are added to modify the taste and make it more acceptable. However, not everyone has the same sense of taste and sensitivity toward…

Twice-yearly drug eases symptoms in chronic rhinosinusitis with polyps

https://medicalxpress.com/news/2025-03-yearly-drug-eases-symptoms-chronic.html

Published: March 4, 2025 10:13

An international collaboration of researchers, sponsored by GSK and working on behalf of the ANCHOR-1 and ANCHOR-2 trial investigators, conducted two Phase III clinical trials to evaluate depemokimab, an ultra-long-acting anti-IL-5 biologic drug, for…

Common malaria drug repurposed to fight cancer

https://medicalxpress.com/news/2025-03-common-malaria-drug-repurposed-cancer.html

Published: March 4, 2025 08:57

Can a drug that's used to treat malaria be repurposed to fight cancer? Researchers at The University of Texas at El Paso have secured a patent for the anti-malarial drug pyronaridine to do just that. Pyronaridine has been used to treat the mosquito-borne…