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The latest news on gastrointestinal and gastroenterology research from Medical Xpress

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Professor urges better prevention and care of liver disease to reduce burden

Published: April 29, 2026 07:00

A University of Houston College of Pharmacy professor has published two studies offering a comprehensive look at chronic liver disease in the era of modern antiviral therapies. One study is the first analysis of its economic and human toll; the other…

Antibiotic use before celiac diagnosis may reflect symptoms, not cause, national study suggests

Published: April 28, 2026 17:20

The risk of celiac disease, an autoimmune reaction driven by gluten, is not a reason to avoid antibiotic treatment. This has been shown by a national study that analyzed the relationship between antibiotics and later celiac disease.

Bile duct cells reveal key pathway that may shape personalized fibrosis treatment

Published: April 28, 2026 16:40

Many liver diseases share a common characteristic: fibrosis, the progressive accumulation of scarring in the liver tissue. Those scars—the liver's response to persistent injuries or attacks—can prevent the organ from functioning properly. Fibrosis affects…

From gut to brain: Scientists engineer bacteria to treat severe liver-related brain dysfunction

Published: April 28, 2026 16:00

When the liver fails, toxins—such as ammonia—that should be filtered from the blood build up and reach the brain. The result is hepatic encephalopathy (HE), a devastating neurological complication of liver disease that can cause anxiety, confusion, memory…

Experimental drug offers new hope for celiac disease treatment

Published: April 28, 2026 13:00

An experimental drug may in future provide a new form of protection for people with celiac disease. According to an international study led by the Universities of Oulu and Tampere, the drug dampens the harmful effects of gluten not only in the gut but also…

World going too slow on eliminating hepatitis: WHO

Published: April 28, 2026 10:40

The World Health Organization on Tuesday said progress in eliminating hepatitis was too slow, with tools available to eliminate the disease that kills more than one million people annually.

Fruit and nuts fight non-alcoholic fatty liver disease

Published: April 28, 2026 09:20

Eating fruit and nuts can help protect against non-alcoholic fatty liver disease (NAFLD)—but a popular fiber supplement can make the condition worse, research by Edith Cowan University (ECU) has found. The paper, "Ellagic Acid Reduces Inulin's Adverse…

Repurposed cancer drugs may help repair gut barrier in Crohn's disease

Published: April 27, 2026 15:40

University of Houston biologists have contributed to a potential breakthrough in treating Crohn's disease by shifting the clinical focus from symptom management to addressing a primary underlying cause of the condition. Crohn's disease, a chronic…

Yellow food coloring changes gut microbiome in early life

Published: April 27, 2026 09:40

A food coloring widely used in the U.S. and worldwide has been found to alter the balance of bacteria living in the gut and may cause low levels of inflammation. Researchers will present these findings at the 2026 American Physiology Summit in Minneapolis…

Men and women may differ in how fitness level is linked to gut microbiome diversity

Published: April 27, 2026 09:00

Aerobic fitness may be influenced by microbes in the gut, but men and women appear to show a different connection, according to a first-of-its-kind study. Researchers will present these findings at the 2026 American Physiology Summit in Minneapolis (APS…

Blocking immune 'signal two' expands gut tolerance cells, may open new IBD treatments

Published: April 26, 2026 17:40

Weill Cornell Medicine investigators made an unexpected finding about how the immune system normally suppresses inappropriate chronic inflammation in the intestine, potentially opening new avenues for therapies against inflammatory bowel disease (IBD),…

Microplastics in human liver could be fueling global surge in disease

Published: April 25, 2026 09:00

There is considerable evidence that microplastics and nanoplastics are present in the livers of humans, and wild animal populations on land and in the ocean. Now experts in environmental and human health are investigating whether the presence of these tiny…

New scoring tool shows radiation can reprogram pancreatic tumor environment

Published: April 24, 2026 07:20

A new study by researchers at Fox Chase Cancer Center focusing on pancreatic cancer has shown that a new scoring system can provide a single numerical value that reflects whether the tumor microenvironment, the biological "neighborhood" surrounding a…

Rectal cancer is striking earlier and killing faster

Published: April 23, 2026 22:40

Rectal cancer deaths among older millennials are accelerating, with growth in mortality far outpacing colon cancer, suggesting primary care doctors should fully investigate early symptoms in patients under age 45, according to a study to be presented at…

Uncovering hidden genetic risks for early-onset and familial colorectal cancer

Published: April 23, 2026 18:20

Researchers and clinicians from National Taiwan University (NTU) and NTU Hospital have compiled the first large-scale genetic database for colorectal cancer (CRC) in Taiwan. This initiative identified inherited genetic abnormalities specifically linked to…

New cellular target prevents hepatitis E infection

Published: April 23, 2026 18:00

An international team of researchers has identified a promising new approach for treating infections with the Hepatitis E virus (HEV). At the center of the study is the drug Apilimod, which specifically blocks the entry of the virus into human liver cells,…

Simple 'gut reset' procedure may prevent weight rebound following GLP-1 discontinuation

Published: April 23, 2026 18:00

An outpatient procedure may offer a way for the estimated 70% of people who discontinue popular weight-loss drugs to avoid regaining the pounds they shed, according to a study presented at Digestive Disease Week (DDW) 2026.

The one-two punch of stress and nighttime eating may lead to toilet trouble

Published: April 23, 2026 16:40

It's well known that chronic stress can disrupt bowel function, sending people running to the bathroom or making them constipated. New research presented at Digestive Disease Week (DDW) 2026 suggests that eating late at night amplifies these effects, with…

New clues to hepatitis B species restriction could help build a novel model for studying infection

Published: April 22, 2026 19:20

Some 254 million people live with a chronic hepatitis B (HBV) infection that is often asymptomatic for decades, only to emerge in an advanced stage of disease that turns to fatal cirrhosis or liver cancer in nearly a million people every year. The…

Scientists uncover how the intestine balances cell growth and maintenance

Published: April 22, 2026 16:20

A new preclinical study from Weill Cornell Medicine found that the protein caspase-5 (CASP5), long thought to be a foot soldier in the body's defense against bacterial infection, does not actually help clear invaders the way its close cousin caspase-4…

Five health conditions mothers can develop after giving birth

Published: April 22, 2026 14:40

During pregnancy, a mother's body undergoes vast structural and functional changes. But what many might not know is that the after-effects of these changes can last long after giving birth—and can even result in the development of new health conditions.