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Clinical trial shows constipation drug can treat patients with chronic kidney disease

https://medicalxpress.com/news/2025-08-clinical-trial-constipation-drug-patients.html

Published: August 29, 2025 14:00

Chronic kidney disease (CKD) is a major health issue worldwide. Many patients end up requiring regular dialysis to avoid kidney failure and stay alive. Despite the severity of the condition, there are currently no drugs available that improve kidney…

Analysis aims to ease GI symptoms for cancer patients

https://medicalxpress.com/news/2025-08-analysis-aims-ease-gi-symptoms.html

Published: August 28, 2025 11:58

Many modern cancer treatments are highly effective at reducing or eliminating tumors, but they can also cause severe gastrointestinal symptoms that impact patients' quality of life or lead to discontinuation of treatment. A new analysis from University of…

Gastrointestinal tumor microbes may predict prognosis and inform treatment

https://medicalxpress.com/news/2025-08-gastrointestinal-tumor-microbes-prognosis-treatment.html

Published: August 28, 2025 09:04

Microbes inside cancerous tumors can influence the spread of disease and the effectiveness of treatment. Those roles make them appealing targets for new therapies and offer ways to better predict risk. Tumor microbiota-based tools could help identify…

Longitudinal study reveals how short bowel syndrome treatment transforms the intestine at a cellular level

https://medicalxpress.com/news/2025-08-longitudinal-reveals-short-bowel-syndrome.html

Published: August 27, 2025 15:05

Short bowel syndrome (SBS) is one of the most challenging conditions in gastroenterology, affecting patients who have lost significant portions of their small intestine due to surgery, disease or congenital abnormalities. Patients with SBS often struggle…

Researchers identify new therapeutic target in advanced gastrointestinal stromal tumors

https://medicalxpress.com/news/2025-08-therapeutic-advanced-gastrointestinal-stromal-tumors.html

Published: August 27, 2025 14:41

Gastrointestinal stromal tumors (GISTs) are the most common type of sarcoma, often driven by mutations in the KIT or PDGFRA genes. Tyrosine kinase inhibitors (TKIs) like imatinib have been the cornerstone of treatment, but most patients eventually develop…

AI analysis of colonoscopy improves assessment of Crohn's disease

https://medicalxpress.com/news/2025-08-ai-analysis-colonoscopy-crohn-disease.html

Published: August 27, 2025 12:21

In a new study, artificial intelligence matched and potentially exceeded the performance of gastroenterologists and conventional scoring in evaluating endoscopies of Crohn's disease patients.

First enzyme-targeting drug reverses damage in metabolic fatty liver disease

https://medicalxpress.com/news/2025-08-enzyme-drug-reverses-metabolic-fatty.html

Published: August 27, 2025 12:18

Researchers at the University of California San Diego School of Medicine have identified a new investigational drug that shows promise in treating metabolic dysfunction-associated steatohepatitis (MASH), a serious form of fatty liver disease linked to…

How alcohol opens the floodgates for harmful bacteria to reach the liver

https://medicalxpress.com/news/2025-08-alcohol-floodgates-bacteria-liver.html

Published: August 26, 2025 16:55

Alcohol-associated liver disease (ALD) is a major cause of liver transplantation and death worldwide, and its impact is only growing. In 2022, the annual cost of ALD in the United States was $31 billion. By 2040, this number could be as high as $66…

What to know about colon cancer

https://medicalxpress.com/news/2025-08-colon-cancer.html

Published: August 26, 2025 07:30

Colon cancer screening myths and facts.

Research uncovers why IBD causes blood clots—and how to prevent them

https://medicalxpress.com/news/2025-08-uncovers-ibd-blood-clots.html

Published: August 25, 2025 16:23

Inflammatory bowel disease, in which the immune system attacks the gut, is a painful chronic condition that affects three million Americans. Rates of IBD are rising, and there's currently no cure. IBD can also be deadly: Up to 8% of people with the disease…

How subtle bacterial shifts keep gut inflammation at bay

https://medicalxpress.com/news/2025-08-subtle-bacterial-shifts-gut-inflammation.html

Published: August 25, 2025 15:59

One of the most captivating mysteries about the immune system is how it manages to keep its healthy equilibrium—staying on high alert and ready to react to harmful invaders or damaged cells, while remaining calm in the presence of innocent triggers such as…

Gut bacteria show promise as a non-invasive, low-cost screening tool for colorectal cancer

https://medicalxpress.com/news/2025-08-gut-bacteria-invasive-screening-tool.html

Published: August 25, 2025 15:14

Colorectal cancer is the second leading cause of cancer death worldwide. If detected early, it can be efficiently treated, but the cost and discomfort of colonoscopies—the main diagnostic method currently in use—often result in delayed diagnosis.

Alcohol withdrawal therapy linked to healthy changes in the gut microbiome

https://medicalxpress.com/news/2025-08-alcohol-therapy-linked-healthy-gut.html

Published: August 25, 2025 13:50

Alcohol withdrawal is associated with positive changes in the composition and function of the gut microbiome, improving our understanding of the gut's influence on physiological and behavioral health, including alcohol craving, a new study suggests. The…

Mouth to gut bacteria migration explains why smoking is good for inflamed bowels

https://medicalxpress.com/news/2025-08-mouth-gut-bacteria-migration-good.html

Published: August 25, 2025 13:09

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered why smoking tobacco helps people suffering from ulcerative colitis, a chronic disease typified by inflammation of the large intestine.

Kidney fibrosis linked to molecule made by gut bacteria

https://medicalxpress.com/news/2025-08-kidney-fibrosis-linked-molecule-gut.html

Published: August 25, 2025 13:00

A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis—a serious complication of diabetes and a leading cause of kidney failure—according to a new study from…

Shame linked to lower quality of life in chronic gut disorders

https://medicalxpress.com/news/2025-08-shame-linked-quality-life-chronic.html

Published: August 25, 2025 11:55

Feelings of shame are linked to reduced quality of life—as shown by the first study to measure shame as a factor influencing the connection between chronic gastrointestinal disorders and mental health.

Light pills could transform understanding of how the gut controls the body

https://medicalxpress.com/news/2025-08-pills-gut-body.html

Published: August 25, 2025 11:22

Scientists have long struggled with how to study the gut's vast nervous system—often called the body's "second brain"—without damaging it. Current research methods are invasive and often require complex surgeries that make it difficult to study normal gut…

Exercise intensity could be impacting your gut

https://medicalxpress.com/news/2025-08-intensity-impacting-gut.html

Published: August 25, 2025 10:30

While exercise is great for both your mental and physical health, new research from Edith Cowan University (ECU) has found that exercise intensity could result in changes to the internal gut biome.

Why does my child's stomach hurt? 5 common causes of stomach pain in kids

https://medicalxpress.com/news/2025-08-child-stomach-common-pain-kids.html

Published: August 25, 2025 09:58

"My stomach hurts." It's one of the most common complaints from school-aged children and young teens. Occasional stomach pain in kids is normal, but when it happens often, it's important to know the most common causes—and when to call your pediatrician.

Gut check: Glycemic control, not body weight, may sway how we choose what to eat

https://medicalxpress.com/news/2025-08-gut-glycemic-body-weight-sway.html

Published: August 25, 2025 09:13

Maybe you shouldn't always listen to your gut.

What does an IBD diagnosis mean?

https://medicalxpress.com/news/2025-08-ibd-diagnosis.html

Published: August 24, 2025 09:40

Inflammatory bowel disease, or IBD, is an umbrella term for a group of chronic conditions that cause inflammation and swelling in the digestive tract. It primarily includes two conditions: ulcerative colitis and Crohn's disease. While both involve…

Yogurt and hot spring bathing show a promising combination for gut health

https://medicalxpress.com/news/2025-08-yogurt-hot-combination-gut-health.html

Published: August 22, 2025 12:41

Researchers at Kyushu University have demonstrated that yogurt intake increases the diversity of gut microbiota and alters its composition. Furthermore, bathing in chloride hot springs after yogurt intake was found to improve defecation status more than…

Bariatric surgery linked to improved IBD outcomes in patients with obesity

https://medicalxpress.com/news/2025-08-bariatric-surgery-linked-ibd-outcomes.html

Published: August 21, 2025 16:25

For patients with inflammatory bowel disease and obesity, bariatric surgery is associated with improved inflammatory bowel disease-related outcomes, according to a study published online July 22 in BJS Open.

Worse emotional health-related quality of life seen for women with cirrhosis, ascites

https://medicalxpress.com/news/2025-08-worse-emotional-health-quality-life.html

Published: August 21, 2025 13:20

Women with cirrhosis and ascites experience worse health-related quality of life (HRQoL) than men, although no difference is seen in daily function, according to a study published in the August issue of the American Journal of Gastroenterology.

Broccoli can have a protective effect against colon cancer, study reveals

https://medicalxpress.com/news/2025-08-broccoli-effect-colon-cancer-reveals.html

Published: August 21, 2025 09:30

The broccoli and Brussels sprouts that often get pushed to the edge of the plate might aid in reducing the risk of colon cancer.

Red meat gut byproduct linked to elevated risk of abdominal aortic aneurysms

https://medicalxpress.com/news/2025-08-red-meat-gut-byproduct-linked.html

Published: August 20, 2025 11:00

Cleveland Clinic researchers have discovered a connection between elevated blood levels of TMAO (trimethylamine N-oxide)—a byproduct of gut bacteria digestion of nutrients found in red meat and other animal products—and a higher risk of abdominal aortic…

Red meat triggers gut bacteria shift, fueling inflammation in mouse study

https://medicalxpress.com/news/2025-08-red-meat-triggers-gut-bacteria.html

Published: August 20, 2025 03:10

Epidemiological studies have revealed a strong correlation between red meat consumption and the development of inflammatory bowel disease. In a new study published in Molecular Nutrition and Food Research that was conducted in mice, red meat consumption…

Gastroesophageal reflux disease linked to increased incidence of pulmonary disease

https://medicalxpress.com/news/2025-08-gastroesophageal-reflux-disease-linked-incidence.html

Published: August 19, 2025 18:30

The presence of gastroesophageal reflux disease (GERD) is associated with an increased incidence of pulmonary diseases, but this effect may be attenuated with GERD treatment, according to research published online July 22 in Frontiers in Cell and…

Gut microbiota linked to autism spectrum disorder progression in mice

https://medicalxpress.com/news/2025-08-gut-microbiota-linked-autism-spectrum.html

Published: August 19, 2025 15:29

Autism spectrum disorder (ASD) affects an estimated 1 in 31 children in the United States by 2025, and prevalence in East Asian countries, such as South Korea, Singapore, and Japan, may be even higher than those in the United States. Despite its increasing…

Studies show food additives could be harmful to the gut

https://medicalxpress.com/news/2025-08-food-additives-gut.html

Published: August 19, 2025 13:30

Animal studies suggest that some food additives, such as artificial colorants and sweeteners, emulsifiers, and antimicrobial preservatives, could be harmful to gut health. A recent review published in The FASEB Journal summarizes the literature and finds…

Global study warns hepatitis B care must be overhauled to meet WHO 2030 elimination targets

https://medicalxpress.com/news/2025-08-global-hepatitis-overhauled.html

Published: August 19, 2025 09:17

The first global systematic review and meta-analysis of hepatitis B care has found critical patient losses at every step of care, calling for decentralized, integrated models to improve diagnosis, treatment, and patient retention.

Understanding how cells in small intestine of patients with celiac disease communicate with one another

https://medicalxpress.com/news/2025-08-cells-small-intestine-patients-celiac.html

Published: August 18, 2025 14:46

A new comprehensive atlas of cells fills gaps in knowledge on how different cells in the intestine act together to drive celiac disease, potentially opening new avenues for future therapeutic intervention.