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Vitamin B12 identified as a potential therapeutic agent in the prevention and treatment of acute pancreatitis

https://medicalxpress.com/news/2024-10-vitamin-b12-potential-therapeutic-agent.html

Published: October 17, 2024 16:37

Acute pancreatitis (AP), which affects people of all ages, is one of the leading causes of hospital admission due to gastrointestinal diseases. Approximately 20% of patients develop moderate or severe acute pancreatitis, which carries extremely high…

Scientists develop tools to identify intestinal nutrient sensors

https://medicalxpress.com/news/2024-10-scientists-tools-intestinal-nutrient-sensors.html

Published: October 17, 2024 14:00

A multi-institutional group of researchers led by the Hubrecht Institute and Roche's Institute of Human Biology has developed strategies to identify regulators of intestinal hormone secretion. In response to incoming food, these hormones are secreted by…

Researchers identify gene linked to severe ulcerative colitis

https://medicalxpress.com/news/2024-10-gene-linked-severe-ulcerative-colitis.html

Published: October 17, 2024 12:19

Abdominal pain, diarrhea, and debilitating fatigue define the daily lives of millions of people worldwide who suffer from chronic bowel disease. Most of these individuals are diagnosed in their youth, and the disease's progression can vary significantly,…

Study links PFAS exposure to kidney function decline via gut microbiome

https://medicalxpress.com/news/2024-10-links-pfas-exposure-kidney-function.html

Published: October 17, 2024 10:32

New research has revealed that the connection between per- and polyfluoroalkyl substances, or PFAS, and kidney damage may be tied to dysregulation of the gut microbiome, which is made up of bacteria and other microorganisms that live in the digestive…

AI models help redefine core microbiome for personalized therapies

https://medicalxpress.com/news/2024-10-ai-redefine-core-microbiome-personalized.html

Published: October 16, 2024 16:32

Researchers at Rutgers University-New Brunswick, along with international collaborators, have introduced a novel method for identifying the crucial set of gut microbes commonly found in humans and essential for health.

Gut flora differs in patients with epilepsy and cognitive dysfunction

https://medicalxpress.com/news/2024-10-gut-flora-differs-patients-epilepsy.html

Published: October 16, 2024 16:10

There is an imbalance in the gut flora of patients with epilepsy compared with healthy controls, according to a study published online Sept. 28 in the Journal of Health, Population and Nutrition.

Breast cancer drug shows potential for rare appendix cancer

https://medicalxpress.com/news/2024-10-breast-cancer-drug-potential-rare.html

Published: October 16, 2024 16:00

Researchers at University of California San Diego School of Medicine found an FDA-approved drug used to treat breast cancer has the potential to be an effective therapeutic for a specific type of appendix cancer.

Magnifying US gastrointestinal disease mortality reveals health disparities

https://medicalxpress.com/news/2024-10-magnifying-gastrointestinal-disease-mortality-reveals.html

Published: October 16, 2024 09:32

Diseases affecting the digestive system, including the upper gastrointestinal (GI) tract, chronic liver disease, cirrhosis, inflammatory bowel disease and others, are significant causes of death worldwide. Mayo Clinic and North Dakota State University…

Promising treatment for gastrointestinal stromal tumors

https://medicalxpress.com/news/2024-10-treatment-gastrointestinal-stromal-tumors.html

Published: October 15, 2024 08:57

About 1,200 Germans are diagnosed with gastrointestinal stromal tumors every year—a rare type of cancer in which the tumors develop in the walls of the digestive organs and quickly develop resistance to common precision drugs.

Using genes to predict whether a different diet helps irritable bowel syndrome

https://medicalxpress.com/news/2024-10-genes-diet-bowel-syndrome.html

Published: October 15, 2024 08:56

Irritable bowel syndrome (IBS) is a digestive disorder characterized by abdominal pain, bloating, diarrhea or constipation. It affects up to 10% of the world's population. Despite its prevalence, the treatment of IBS remains a challenge, as the symptoms…

Clinical trials confirm zolbetuximab's efficacy in gastric cancer

https://medicalxpress.com/news/2024-10-clinical-trials-zolbetuximab-efficacy-gastric.html

Published: October 14, 2024 15:34

In Germany, around 17,000 people are diagnosed with gastric cancer every year. The disease is one of the leading causes of tumor-related deaths. This is due to late diagnosis and the rapid spread of tumor cells throughout the body.

Does the gut microbiome affect spine health?

https://medicalxpress.com/news/2024-10-gut-microbiome-affect-spine-health.html

Published: October 14, 2024 10:14

Are back problems influenced by your gut? Researchers at Rush think there may be a connection.

Novel procedure combined with semaglutide may eliminate insulin dependency in type 2 diabetes

https://medicalxpress.com/news/2024-10-procedure-combined-semaglutide-insulin-diabetes.html

Published: October 13, 2024 18:00

Groundbreaking research presented at UEG Week 2024 reveals a promising new treatment strategy for type 2 diabetes (T2D) that could significantly reduce or even eliminate the need for insulin therapy.

Chronic stress accelerates colorectal cancer progression by disrupting the balance of gut microbiota, study shows

https://medicalxpress.com/news/2024-10-chronic-stress-colorectal-cancer-disrupting.html

Published: October 12, 2024 18:00

Cutting-edge research has uncovered how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer (CRC), opening new avenues for CRC prevention and treatment.

Inflammatory bowel diseases may be detectable at birth

https://medicalxpress.com/news/2024-10-inflammatory-bowel-diseases-birth.html

Published: October 11, 2024 13:46

Across the Western world, the prevalence of inflammatory bowel diseases, which have no cure, is rising. In Denmark alone, 50,000 people suffer from either Crohn's disease or ulcerative colitis, which represents a doubling in cases over the past 20 years.…

Possible trigger of Crohn's disease discovered: Dysfunctional mitochondria disrupt the gut microbiome

https://medicalxpress.com/news/2024-10-trigger-crohn-disease-dysfunctional-mitochondria.html

Published: October 11, 2024 11:07

Disruptions of mitochondrial functions have a fundamental influence on Crohn's disease. This connection has now been demonstrated by researchers at the Technical University of Munich (TUM). In a study published in Cell Host & Microbe, they show that…

Too much lactate can harm our health—these microbes in our gut keep it in check

https://medicalxpress.com/news/2024-10-lactate-health-microbes-gut.html

Published: October 11, 2024 08:40

Lactate will be familiar to many due to a common belief that it causes muscle "burn" following exercise—but this is a myth.

Study determines higher dosage of radioembolization to treat liver cancer improves survival rates

https://medicalxpress.com/news/2024-10-higher-dosage-radioembolization-liver-cancer.html

Published: October 10, 2024 17:11

A study led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) and Singapore General Hospital (SGH) has determined the benefits of using a higher dosage of radioembolization treatment using yttrium-90 (Y-90)…

Faulty 'fight or flight' response drives deadly C. difficile infections, research reveals

https://medicalxpress.com/news/2024-10-faulty-flight-response-deadly-difficile.html

Published: October 10, 2024 12:44

The portion of our nervous systems responsible for the "fight or flight" response can shape the severity of potentially deadly C. difficile infections, new research from the University of Virginia School of Medicine reveals.

Metabolic syndrome factors linked to increased bowel cancer risk

https://medicalxpress.com/news/2024-10-metabolic-syndrome-factors-linked-bowel.html

Published: October 10, 2024 11:20

Metabolic disorders such as obesity, high blood pressure and non-alcoholic fatty liver diseases have been directly linked to an increased risk of developing bowel cancer, warn Flinders University researchers.

What a tiny, 3D gut can tell us about gastrointestinal disorders

https://medicalxpress.com/news/2024-10-tiny-3d-gut-gastrointestinal-disorders.html

Published: October 10, 2024 09:19

The relationship between our nervous and digestive systems is a relatively new area of scientific study. But what Northeastern University researcher Abigail Koppes calls the "brain gut" connection has vast implications for our overall health that we're…

Lachnospiraceae could be key to successful fecal transplants

https://medicalxpress.com/news/2024-10-lachnospiraceae-key-successful-fecal-transplants.html

Published: October 9, 2024 15:02

Fecal microbiota transplants, or FMTs, are a magic bullet for patients with recurring infections from Clostridioides difficile (C. diff), but researchers are only beginning to understand why. A new in-depth study of pre- and post-transplant microbiomes…