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Activation of receptors involved in gut microbial breakdown of fiber may cut heart disease risk by up to 20%

https://medicalxpress.com/news/2025-05-receptors-involved-gut-microbial-breakdown.html

Published: May 23, 2025 04:04

A Monash University study of almost 400,000 people, published in the journal Cardiovascular Research , is the first to indicate, in humans, that the signaling of substances called short-chain fatty acids or SCFAs, released when gut bacteria break down…

Vibrating capsule shown to be safe, tolerable in treating chronic idiopathic constipation

https://medicalxpress.com/news/2025-05-vibrating-capsule-shown-safe-tolerable.html

Published: May 22, 2025 15:10

A study offers new hope to millions suffering from chronic idiopathic constipation (CIC). Published in a recent issue of Neurogastroenterology & Motility, the study, titled "The Vibrating Capsule: Safety and Tolerability in Patients With Chronic Idiopathic…

Study links gut health to fatigue in post-COVID syndrome patients

https://medicalxpress.com/news/2025-05-links-gut-health-fatigue-covid.html

Published: May 21, 2025 12:49

In a recent study, a research team from the Medical University of Vienna has gained new insights into post-COVID syndrome (PCS) and the relevance of a healthy gastrointestinal tract. The study, which was recently published in the journal Allergy, shows…

Rat study indicates strawberry tree extract may prevent and treat ulcerative colitis

https://medicalxpress.com/news/2025-05-rat-strawberry-tree-ulcerative-colitis.html

Published: May 21, 2025 04:52

New research in rats indicates that a Mediterranean plant may be an effective treatment for ulcerative colitis, a type of inflammatory bowel disease. The findings are published in the Journal of the Science of Food and Agriculture.

Key chemical discovered as potent stimulator of esophageal and upper stomach muscle movement

https://medicalxpress.com/news/2025-05-key-chemical-potent-esophageal-upper.html

Published: May 20, 2025 16:47

A research group has discovered that a natural substance in the body, known as platelet-activating factor (PAF), can strongly stimulate muscle movements in parts of the digestive system, especially the esophagus and the upper part of the stomach.

Gut microbes may help protect patients from chemotherapy side effects

https://medicalxpress.com/news/2025-05-gut-microbes-patients-chemotherapy-side.html

Published: May 20, 2025 15:39

Chemotherapy doesn't just kill cancer cells. It also affects the microbes in the digestive tract. Researchers at UC San Francisco have discovered that some gut bacteria can reduce the side effects of these potent treatments, and that one family of cancer…

Advanced genomics study improves detection of hard-to-find diarrheal infections

https://medicalxpress.com/news/2025-05-advanced-genomics-hard-diarrheal-infections.html

Published: May 20, 2025 11:27

A University of Liverpool study has used advanced genetic and genomic techniques to offer a major step forward in understanding and diagnosing infectious intestinal diseases. The research is published in the journal Genome Medicine.

Fast food, fast impact: How fatty meals rapidly weaken our gut defenses

https://medicalxpress.com/news/2025-05-fast-food-impact-fatty-meals.html

Published: May 19, 2025 10:24

A WEHI-led study has become the first in the world to unravel the immediate effects of a high-fat diet on our gut health. The pre-clinical study, published in Immunity, found even a few meals high in saturated fats can cause inflammation in the body,…

New cause of chronic inflammation in ulcerative colitis discovered

https://medicalxpress.com/news/2025-05-chronic-inflammation-ulcerative-colitis.html

Published: May 19, 2025 10:20

It is estimated that more than 5 million people worldwide suffer from ulcerative colitis, a chronic inflammation of the colon that often progresses in stages whose causes have not yet been fully investigated. A new international study with the…

Positive proof-of-concept experiments may lead to the world's first treatment for celiac disease

https://medicalxpress.com/news/2025-05-positive-proof-concept-world-treatment.html

Published: May 19, 2025 08:50

An investigational treatment for celiac disease effectively controls the condition—at least in an animal model—in a first-of-its-kind therapeutic for a condition that affects approximately 70 million people worldwide.

Chronic pain and mental well-being linked to IBS risk: Genetic study identifies modifiable factors

https://medicalxpress.com/news/2025-05-chronic-pain-mental-linked-ibs.html

Published: May 16, 2025 11:57

Irritable bowel syndrome (IBS) is a prevalent and debilitating gastrointestinal disorder affecting approximately 5%–10% of the global population. Characterized by abdominal pain, bloating, and altered bowel habits, IBS imposes a significant burden on…

Oral norovirus vaccine candidate successfully tested in human challenge trial

https://medicalxpress.com/news/2025-05-oral-norovirus-vaccine-candidate-successfully.html

Published: May 16, 2025 09:12

Vaxart Inc., in collaboration with researchers from multiple academic institutions, evaluated the VXA-G1.1-NN vaccine against norovirus infection. Findings show a 30% reduction in infection rates among vaccinated participants compared to those receiving a…

Betrayed by bile ducts? Researchers look for clues to treating a mysterious autoimmune disease

https://medicalxpress.com/news/2025-05-betrayed-bile-ducts-clues-mysterious.html

Published: May 15, 2025 21:10

Your bile duct network is a true tree of life. A floppy, pink tree of life.

Researchers discover gut bacteria 'weapon' and redirect it toward cancer

https://medicalxpress.com/news/2025-05-gut-bacteria-weapon-redirect-cancer.html

Published: May 15, 2025 13:27

University of Oklahoma researchers have discovered that some bacteria in the gut have their own unique "weapon system" to compete against other bacteria for dominance. Importantly, there is promising evidence that this system can be repurposed to target…

Study finds shorter radiotherapy course treats anal cancer while reducing treatment burden

https://medicalxpress.com/news/2025-05-shorter-radiotherapy-anal-cancer-treatment.html

Published: May 15, 2025 12:49

Patients and clinicians have welcomed the results of the ACT4 PLATO trial, which was the first clinical trial in the world to randomly assign patients with anal cancer to receive different doses of radiotherapy.

Inhibiting a cell death receptor restores mucosal healing in inflammatory bowel diseases, study finds

https://medicalxpress.com/news/2025-05-inhibiting-cell-death-receptor-mucosal.html

Published: May 15, 2025 12:00

An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from the University of Milan highlights the beneficial effect of inhibiting the death receptor TMEM219 to restore mucosal healing in…

'Rogue' immune cells explain why a gluten-free diet fails in some celiac patients

https://medicalxpress.com/news/2025-05-rogue-immune-cells-gluten-free.html

Published: May 15, 2025 09:02

Researchers at the Garvan Institute of Medical Research and UNSW Sydney have discovered why some people with celiac disease continue to suffer debilitating symptoms despite strictly avoiding gluten.

Low FODMAP diet can ease symptoms of those with endometriosis

https://medicalxpress.com/news/2025-05-fodmap-diet-ease-symptoms-endometriosis.html

Published: May 14, 2025 16:10

A low FODMAP diet developed by Monash University researchers for irritable bowel syndrome (IBS) has been shown to improve gastrointestinal symptoms in women with endometriosis.

Lipid-based communication between body and gut microbes can trigger beneficial immune responses

https://medicalxpress.com/news/2025-05-lipid-based-communication-body-gut.html

Published: May 14, 2025 11:00

The human gut is home to trillions of microbes that not only aid in digestion, but also play a key role in shaping our immune system. These microbes communicate with the body by releasing a range of molecules that influence how immune cells grow and…