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Once-daily oral icotrokinra outperforms placebo in ulcerative colitis

https://medicalxpress.com/news/2026-10-daily-oral-icotrokinra-outperforms-placebo.html

Published: October 23, 2026 22:00

For patients with moderately to severely active ulcerative colitis, oral icotrokinra, a peptide that blocks the interleukin-23 receptor, yields a clinical response at week 12 significantly more often than placebo, according to a study published in the Oct.…

Study identifies potential new treatment targets for the most common type of bowel cancer

https://medicalxpress.com/news/2026-10-potential-treatment-common-bowel-cancer.html

Published: October 23, 2026 15:20

Research published today identifies potential new ways to treat the most common type of colorectal cancer in Ireland. The study, conducted by an international research team led by RCSI University of Medicine and Health Sciences and The Institute of Cancer…

FDA approves hepatitis B shot that may let some patients stop all treatment

https://medicalxpress.com/news/2026-10-fda-hepatitis-shot-patients-treatment.html

Published: October 23, 2026 13:00

Some adults with chronic hepatitis B may now have a path to something today's treatments rarely deliver—stopping all medication while the virus stays in check.

Gut microbiome may help explain why sleep improvement varies after hydrogen supplementation

https://medicalxpress.com/news/2026-10-gut-microbiome-varies-hydrogen-supplementation.html

Published: October 23, 2026 09:12

A Hiroshima University–led clinical trial found that hydrogen supplementation did not significantly improve sleep quality compared with a placebo; however, exploratory analyses suggest that differences in the abundance of hydrogen-producing gut bacteria…

Nurses are an important resource in Swedish bowel cancer screening

https://medicalxpress.com/news/2026-10-nurses-important-resource-swedish-bowel.html

Published: October 22, 2026 17:40

Colonoscopies performed by specially trained nurses as part of the Swedish bowel cancer screening program are of at least the same quality as those performed by doctors, according to a study from Karolinska Institutet published in the journal Endoscopy.…

Common multiple sclerosis treatment linked to bowel disease risk

https://medicalxpress.com/news/2026-10-common-multiple-sclerosis-treatment-linked.html

Published: October 22, 2026 17:00

People with multiple sclerosis (MS) who are treated with rituximab have an increased risk of developing inflammatory bowel disease, particularly Crohn's disease, although the absolute risk remains low. This is according to the first large population-based…

No disease recurrences after short course of neoadjuvant immunotherapy, according to follow-up

https://medicalxpress.com/news/2026-10-disease-recurrences-short-neoadjuvant-immunotherapy.html

Published: October 22, 2026 15:20

A short course of neoadjuvant immunotherapy continues to show long-term outcomes in patients with locally advanced mismatch repair–deficient (dMMR) colon cancer. In the NICHE-2 study, none of the 111 patients in the primary efficacy population experienced…

Liver tumors form without detectable driver mutations in mice, revealing epigenetic route

https://medicalxpress.com/news/2026-10-liver-tumors-driver-mutations-mice.html

Published: October 22, 2026 14:40

Cancers can develop through epigenetic pathways even without driver gene mutations (DGMs), according to a study from Science Tokyo. Researchers uncovered the YAP1–TEAD–TET1 axis, which triggers DNA demethylation and activates multiple oncogenes in…

MRI scans and DNA data uncover new genetic links to fatty liver disease

https://medicalxpress.com/news/2026-10-mri-scans-dna-uncover-genetic.html

Published: October 22, 2026 13:00

Fatty liver disease is characterized by the accumulation of triglycerides—a type of fat—in the liver. The disease has a strong genetic component, but until now, knowledge about which genes influence its development has been limited. To gain a better…

Hypnosis may help relieve stomach pain

https://medicalxpress.com/news/2026-10-hypnosis-relieve-stomach-pain.html

Published: October 22, 2026 08:00

Stomach pain and other gastrointestinal complaints are common among children and adolescents. When symptoms recur over a long period, the cause may be a form of DGBI (disorders of gut-brain interaction), in which communication between the brain and the gut…

First drug-focused guideline outlines newer treatments for primary biliary cholangitis

https://medicalxpress.com/news/2026-10-drug-focused-guideline-outlines-treatments.html

Published: October 22, 2026 05:00

For the first time, a joint guideline from the American Gastroenterological Association (AGA) and American Association for the Study of Liver Diseases (AASLD) evaluates newer medications for primary biliary cholangitis (PBC), the most common cholestatic…

Fitness program for transplant candidates linked to lower mortality

https://medicalxpress.com/news/2026-10-transplant-candidates-linked-mortality.html

Published: October 21, 2026 09:00

When transplant candidates become frail, doctors often worry that they are too weak to survive transplantation. But according to a new study from Northwestern Medicine and the University of Pittsburgh, frailty can be significantly improved with the right…

Gut-friendly fiber formula gives hope to IBS sufferers

https://medicalxpress.com/news/2026-10-gut-friendly-fiber-formula-ibs.html

Published: October 21, 2026 08:00

Relief could be in sight for millions of people living with the pain and discomfort of irritable bowel syndrome (IBS) thanks to a specially formulated fiber that's been created and trialed by researchers at Edith Cowan University (ECU). The study is…

New drug could let some rectal cancer patients skip chemotherapy, radiation and surgery

https://medicalxpress.com/news/2026-10-drug-rectal-cancer-patients-chemotherapy.html

Published: October 20, 2026 21:20

Some people with rectal cancer may now be able to skip chemotherapy, radiation and surgery. The U.S. Food and Drug Administration (FDA) on Monday approved the immunotherapy Jemperli (dostarlimab-gxly) for certain adults with rectal cancer that hasn't been…

AI is helping pathologists find harmful lesions the eye can't see

https://medicalxpress.com/news/2026-10-ai-pathologists-lesions-eye.html

Published: October 20, 2026 15:40

As a pathologist, Dr. Christopher Owens has spent his career trying to improve his methods of catching precancerous colorectal polyps in patients. If he could catch cases earlier, fewer people would develop colorectal cancer, he said.

Body composition changes on CT scans may help identify pancreatic cancer risk

https://medicalxpress.com/news/2026-10-body-composition-ct-scans-pancreatic.html

Published: October 20, 2026 14:20

People who develop pancreatic cancer experience measurable changes in body composition years before diagnosis that differ from those seen in similar individuals without cancer, according to a Mayo Clinic study led by former Mayo Clinic research fellow…

Menopause survey reveals widespread digestive discomfort alongside anxiety across transition

https://medicalxpress.com/news/2026-10-menopause-survey-reveals-widespread-digestive.html

Published: October 20, 2026 10:00

It's not uncommon for women to experience more gastrointestinal (GI) issues, especially bloating and gas, during menopause due to fluctuating hormone levels that slow down digestion and alter gut function. Anxiety is also common. But are the two problems…

Routine liver cancer checks could extend lives below current screening thresholds for alcohol-related cirrhosis

https://medicalxpress.com/news/2026-10-routine-liver-cancer-current-screening.html

Published: October 20, 2026 05:50

A new study led by investigators from Mass General Brigham found routine liver cancer screening to be cost-effective and life-extending for individuals with alcohol-associated cirrhosis, even when their annual risk of developing liver cancer is less than…

Protein discovery reveals potential treatment target for common fatty liver disease

https://medicalxpress.com/news/2026-10-protein-discovery-reveals-potential-treatment.html

Published: October 19, 2026 17:40

The mechanisms that cause the world's most common chronic liver disease—metabolic dysfunction-associated steatotic liver disease (MASLD)—to develop and progress are still not fully understood.

Gut microbiome could help identify people at risk of dementia

https://medicalxpress.com/news/2026-10-gut-microbiome-people-dementia.html

Published: October 19, 2026 12:20

In what is thought to be the first study of its kind, researchers from Cardiff University and Imperial College London examined both gut bacteria and chemicals. Their findings could support earlier diagnosis and help spot people at risk of faster decline.

Antibiotic use from childhood linked to higher odds of IBS in young adulthood

https://medicalxpress.com/news/2026-10-antibiotic-childhood-linked-higher-odds.html

Published: October 18, 2026 18:10

Antibiotic use from childhood through early adulthood was associated with higher odds of irritable bowel syndrome (IBS) at age 24, with the odds increasing as the number of antibiotic prescriptions rose, according to a new study presented at UEG Week 2026.

Immune changes could signal inflammatory bowel disease up to 10 years before diagnosis

https://medicalxpress.com/news/2026-10-immune-inflammatory-bowel-disease-years.html

Published: October 18, 2026 18:10

A large-scale study, presented at UEG Week 2026, has identified distinct antibody patterns up to 10 years before the diagnosis of inflammatory bowel disease (IBD), potentially opening new avenues for earlier risk detection and providing insights into…

Upper endoscopy patients who inhale cannabis may need more anesthesia than edible users

https://medicalxpress.com/news/2026-10-upper-endoscopy-patients-inhale-cannabis.html

Published: October 18, 2026 17:50

Patients who smoke or vape cannabis may need more anesthesia during an upper endoscopy than those who use edibles or do not use cannabis, according to a new study presented at the Anesthesiology 2026 annual meeting.

Disability burden linked to alcohol-related cirrhosis and heart failure projected to rise sharply by 2050

https://medicalxpress.com/news/2026-10-disability-burden-linked-alcohol-cirrhosis.html

Published: October 16, 2026 18:10

The disability burden associated with alcohol-related cirrhosis complicated by heart failure is projected to rise substantially by 2050 across Central Europe, Eastern Europe and the United States (US), according to new research presented at UEG Week 2026.

Imaging-based modalities compared for identifying at-risk MASH

https://medicalxpress.com/news/2026-10-imaging-based-modalities-mash.html

Published: October 16, 2026 14:40

FibroScan-aspartate aminotransferase (FAST) demonstrated the highest sensitivity for ruling out at-risk metabolic dysfunction-associated steatohepatitis (MASH), according to a study published in the October issue of the American Journal of…