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🦜 Gastroenterology and digestive system disorders research news

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The latest news on gastrointestinal and gastroenterology research from Medical Xpress

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Exploring interactions between gut microbiota and sleep disorders through the brain-gut axis

Published: November 4, 2025 01:00

A comprehensive review published in Brain Medicine illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep…

Study shows semaglutide, tirzepatide and dulaglutide have similar gastrointestinal safety profiles in clinical settings

Published: November 3, 2025 17:00

A new observational study compared the risk for severe gastrointestinal adverse events across dulaglutide, semaglutide, and tirzepatide in patients with type 2 diabetes (T2D). The study found that the medications have similar gastrointestinal safety…

Gut microbiome tests are everywhere. Should you get one?

Published: November 3, 2025 09:50

At-home gut microbiome tests are trending, selling insights to the curious, empowerment to the chronically ill and a claimed path to longevity to the wellness-conscious.

Q&A: Bacteria research could be a gut-punch to inflammatory bowel disease

Published: October 31, 2025 18:10

The group of lifelong intestinal conditions known as inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, significantly impacts digestive health and quality of life for an estimated 2.4 and 3.1 million people in the U.S.

Researchers map how gut neurons respond to bacteria, parasites and food allergies

Published: October 31, 2025 11:38

The enteric nervous system (ENS) is a vast network of nerves built into the walls of the intestine. While it is well known for its role in regulating digestion and the movement of food through the intestine, researchers are learning that its influence…

Lab-grown liver model offers a platform to study fibrosis and regeneration

Published: October 31, 2025 11:19

As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments. The model recreates interactions between hepatocytes and…

Underweight and unbalanced: Gut microbial diversity in underweight Japanese women

Published: October 31, 2025 10:56

Low body weight in young women has been linked to a range of health concerns, including disrupted menstrual cycles, infertility, weakened immune function, and a long-term decline in bone density. Japan has seen a rising trend in the proportion of…

Maxing out your fiber intake can have broad health benefits

Published: October 31, 2025 07:07

The amount of fiber you consume can have significant impacts on your body. From healthy digestion, to reducing your risk of developing cancer, eating fiber has huge benefits—which may be why the fibermaxxing trend is taking over.

Diets high in sugar and butter lead to changes in gut microbiome linked to excessive alcohol intake in mice

Published: October 30, 2025 13:32

Mice that switched from a high sugar/butter diet to a standard diet developed a strong preference for alcohol over water, in a study exploring the connection between gastrointestinal microorganisms and alcohol use disorder (AUD). The findings, published in…

Babies' gut bacteria may influence future emotional health

Published: October 30, 2025 06:00

A child's early gut microbiome may influence their risk of developing depression, anxiety or other internalizing symptoms in middle childhood, according to a new UCLA Health study. The effect appears to be related to the way bacteria are linked to…

Demographic disparities found in uptake of colorectal cancer screenings

Published: October 29, 2025 12:12

Colorectal cancer (CRC) screening is considered one of the most effective and successful tools to protect public health: Screening has been found to significantly reduce the incidence of CRC through the removal of precancerous polyps during colonoscopies…

1 in 10 people without celiac disease or wheat allergy report sensitivity to gluten or wheat, finds study

Published: October 28, 2025 18:30

Around one in ten people worldwide report gastrointestinal and other symptoms such as fatigue and headache after eating foods containing gluten or wheat despite not having a diagnosis of either celiac disease or wheat allergy, finds a large systematic…

How bacteria that cause inflammatory colitis outmaneuver our body's defenses

Published: October 28, 2025 13:13

Bacteria use multiple defense mechanisms to survive in the host body. Shigella bacteria that cause colitis disable multiple host defense pathways using three specialized effector proteins, as reported by researchers from Japan. They found that these…

Protecting the gut after stem cell transplantation: New evidence uncovered for potential of microbiome-based therapies

Published: October 28, 2025 12:03

Patients receiving intensive cancer treatments—such as radiation or stem cell transplantation—often suffer from severe damage to the intestinal lining. This not only causes pain and complications but also worsens long-term outcomes. A Nature Communications…

A Mediterranean diet could be the place to start when tackling IBS

Published: October 28, 2025 08:50

A randomized clinical trial has found that the Mediterranean diet is superior to traditional diet advice in managing irritable bowel syndrome (IBS) symptoms, suggesting that it could be considered a viable first-line dietary intervention for IBS. The study…

Magnetic robotic valve offers minimally invasive option for acid reflux treatment

Published: October 27, 2025 12:45

A team of researchers led by Xiaoguang Dong, assistant professor of mechanical and biomedical engineering at Vanderbilt University, have developed a magnetic robotic valve to provide minimally invasive intervention for gastroesophageal reflux disease and…