🦜 Hypothesis Stream
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How To Fix DEI
https://hypothes.is/a/1QSQEGRDEfC--u-0W3VQGQ
Published: July 19, 2025 01:58
no large country has ever successfully transitioned to a majority minority demographic while maintaining a full democracy. Experience suggests that such a transition is much more likely to be blocked than to succeed.Paul's hunch as a child!
POMC neurons control fertility through differential signaling of MC4R in kisspeptin neurons
https://hypothes.is/a/Ji13tmRBEfC--P-qsH7Bkw
Published: July 19, 2025 01:39
RRID:Addgene_20298DOI: 10.7554/eLife.100722 Resource: RRID:Addgene_20298 Curator: @dhovakimyan1 SciCrunch record: RRID:Addgene_20298 What is this?
POMC neurons control fertility through differential signaling of MC4R in kisspeptin neurons
https://hypothes.is/a/JlI9MGRBEfCebctEfjahgw
Published: July 19, 2025 01:39
catalog no. 006414DOI: 10.7554/eLife.100722 Resource: (IMSR Cat# JAX_006414,RRID:IMSR_JAX:006414) Curator: @dhovakimyan1 SciCrunch record: RRID:IMSR_JAX:006414 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JgWclmRBEfCYoF_tgvHnUw
Published: July 19, 2025 01:39
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81289 Curator: @maulamb SciCrunch record: RRID:BDSC_81289 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/Jae6fGRBEfCrqXf4nMGvgQ
Published: July 19, 2025 01:39
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81286 Curator: @maulamb SciCrunch record: RRID:BDSC_81286 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JVjM-mRBEfCvwcv9T2nnzQ
Published: July 19, 2025 01:39
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81285 Curator: @maulamb SciCrunch record: RRID:BDSC_81285 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JcwBwGRBEfCx4mfb7FChZg
Published: July 19, 2025 01:39
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81288 Curator: @maulamb SciCrunch record: RRID:BDSC_81288 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JX7KpGRBEfCisBdxYs4Hcw
Published: July 19, 2025 01:39
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81300 Curator: @maulamb SciCrunch record: RRID:BDSC_81300 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JL3jrGRBEfCg0QfnqZaleA
Published: July 19, 2025 01:39
#81281 - 81302DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81282 Curator: @maulamb SciCrunch record: RRID:BDSC_81282 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JN9qmmRBEfCoyaemOGN3ig
Published: July 19, 2025 01:39
#81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81283 Curator: @maulamb SciCrunch record: RRID:BDSC_81283 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JS8bimRBEfC9Wxu2kfEqLQ
Published: July 19, 2025 01:39
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81287 Curator: @maulamb SciCrunch record: RRID:BDSC_81287 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JQcD6GRBEfCkWhPpGahlvg
Published: July 19, 2025 01:39
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81284 Curator: @maulamb SciCrunch record: RRID:BDSC_81284 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JHU10GRBEfC66T87FrJCiw
Published: July 19, 2025 01:38
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81298 Curator: @maulamb SciCrunch record: RRID:BDSC_81298 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JC2rIGRBEfCfjK83n5Z2lw
Published: July 19, 2025 01:38
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81296 Curator: @maulamb SciCrunch record: RRID:BDSC_81296 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JJdsfGRBEfC5XrP4XaSs8Q
Published: July 19, 2025 01:38
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81299 Curator: @maulamb SciCrunch record: RRID:BDSC_81299 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JEy2-mRBEfC5XQMcV5QSTQ
Published: July 19, 2025 01:38
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81297 Curator: @maulamb SciCrunch record: RRID:BDSC_81297 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/JA0CCGRBEfC-97vvsTXOzg
Published: July 19, 2025 01:38
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81301 Curator: @maulamb SciCrunch record: RRID:BDSC_81301 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/I8sIxmRBEfCXiDvajXUO7w
Published: July 19, 2025 01:38
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81294 Curator: @maulamb SciCrunch record: RRID:BDSC_81294 What is this?
Split-QF System for Fine-Tuned Transgene Expression in Drosophila
https://hypothes.is/a/I-1ESmRBEfCmK59auhERLQ
Published: July 19, 2025 01:38
##81281 - 81302.DOI: 10.1534/genetics.119.302034 Resource: RRID:BDSC_81295 Curator: @maulamb SciCrunch record: RRID:BDSC_81295 What is this?
基层法官职业素质现状探析--中国法学网
https://hypothes.is/a/CLJsHmRBEfCZhNdvnvVQSg
Published: July 19, 2025 01:38
朱苏力教授将基层法院法官的来源分了三类:一是复转军人;二是大专学校毕业生;三是其他地方单位调进的。其实还有一类人苏力教授没有提到,这就是85年(全国法院统一招干)以来历次招…
The Transformation of Silence into Language and Action_by Audre Lorde
https://hypothes.is/a/pqzS3GQuEfCXWg_eRIgJyw
Published: July 18, 2025 23:26
Butweallhurtinsomanydifferentways,allthetime,andpainwilleitherchangeorend.Death,ontheotherhand,isthefinalsilence.This section is a small reminder that we never truly experience silence until death. With that being said, finding your voice and speaking…
The Transformation of Silence into Language and Action_by Audre Lorde
https://hypothes.is/a/c04GNmQuEfClzl-7j-1_fg
Published: July 18, 2025 23:25
I agree. The importance of speaking up about mental and social death has slowly been coming to light in today's society.
The Transformation of Silence into Language and Action_by Audre Lorde
https://hypothes.is/a/TpCuDGQuEfC3gOM3ir6EGw
Published: July 18, 2025 23:24
Thewomenwhosustainedmethroughthatperiodwereblackandwhite,oldandyoung,lesbian,bisexual,andheterosexual,andweallsharedawaragainstthetyranniesofsilence.This section takes me back to when she spoke about how silence is a weakness. The discrimination people…
The Transformation of Silence into Language and Action_by Audre Lorde
https://hypothes.is/a/ExmalmQuEfCYELOfeSk9Iw
Published: July 18, 2025 23:22
Iwasforcedtolookuponmyselfandmylivingwithaharshandurgentclaritythathasleftmestillshakenbutmuchstronger.Thisisasituationfacedbymanywomen,bysomeofyouheretoday.SomeofwhatIexperiencedduringthattimehashelpedelucidateformemuchofwhatIfeelconcerningthetransformati…
urn:x-pdf:8407ad401319d61029ae96fb4e0c7372
https://hypothes.is/a/0ALnXmQsEfCQMyvbS9qhQA
Published: July 18, 2025 23:13
Chaos FortresseSiiiick picture.
urn:x-pdf:8407ad401319d61029ae96fb4e0c7372
https://hypothes.is/a/rbUBxmQpEfCxqRPcq64PzQ
Published: July 18, 2025 22:51
The Realm of Chaos is thebirthplace of heroes, Daemons and monsters, the forgefrom which eternal life or everlasting damnation can bewrought. In reality, the Realm of Chaos is this andincomprehensibly more besides; a cosmically vastrealm where the laws of…
Navigating Failures in Pods With Devices
https://hypothes.is/a/5_5ZbmQoEfCJLNt0t_KWbg
Published: July 18, 2025 22:45
Navigating Failures in Pods With Devices## Summary: Navigating Failures in Pods With Devices
This article examines the unique challenges Kubernetes faces in managing **specialized hardware** (e.g., GPUs, accelerators) within AI/ML workloads, and explores…
urn:x-pdf:8407ad401319d61029ae96fb4e0c7372
https://hypothes.is/a/TFHD3mQoEfCYAmPHB68Pkw
Published: July 18, 2025 22:41
It said that it is better to take your own lifethan to be left at the mercy of Dechala, for the meaningof the word mercy is alien to her.I like this Slaaneshi champ's style, get an army of drug addicts behind you.
Osteoporosis
https://hypothes.is/a/yb7b-mQnEfCyiTvcG2CokA
Published: July 18, 2025 22:37
Ejercicio medicina interna
Paramount’s Trump Settlement: A Big Fat Bribe | Jeffrey Epstein Never Dies | FIFA Trophy Row
https://hypothes.is/a/FVoTYGQmEfC8LocZ82x2jQ
Published: July 18, 2025 22:25
[Paramount’s Trump Settlement: A Big Fat Bribe - Jeffrey Epstein Never Dies - FIFA Trophy Row](https://www.youtube.com/watch?v=zzvx3L3DQb8)
Paramount’s Trump Settlement: A Big Fat Bribe | Jeffrey Epstein Never Dies | FIFA Trophy Row
https://hypothes.is/a/ieJnamQlEfCQJ5_SmQyyww
Published: July 18, 2025 22:21
Watching this three days after it aired and reading headlines like [‘Late Show With Stephen Colbert’ Is Being Canceled by CBS](https://www.nytimes.com/2025/07/17/business/stephen-colbert-late-show-ending.html), it would seem obvious why they're not…
urn:x-pdf:8407ad401319d61029ae96fb4e0c7372
https://hypothes.is/a/hp9jMmQlEfCrcj9HlZsBAw
Published: July 18, 2025 22:21
wo eyes, glitteringlike multi-faceted gems, burning with inner balefires, stared back at him.His armour was covered in twisting eldritch runes that glowed in thedarkness of the Chaos wasteland. His sword gleamed with blue light andseemed to moan as he…
urn:x-pdf:8407ad401319d61029ae96fb4e0c7372
https://hypothes.is/a/StD88GQjEfCzF39uqh98oA
Published: July 18, 2025 22:05
From then on, Gotthard had known he was truly alone. He had riddendown the guards at the River Gate and taken the road to the north. Soonhe was beyond the borders of Reikland, but witch hunters, outriders, andbounty hunters were never far behind. He had…
A stratification system for breast cancer based on basoluminal tumor cells and spatial tumor architecture
https://hypothes.is/a/tc4P9GQhEfC7kWuFeu6qFw
Published: July 18, 2025 21:53
RRID:AB_2134409DOI: 10.1016/j.ccell.2025.06.019 Resource: (Millipore Cat# MAB1611, RRID:AB_2134409) Curator: @scibot SciCrunch record: RRID:AB_2134409 What is this?
How to Stop A Bully So He Regrets It | Russian Mafia Advice
https://hypothes.is/a/ZjyODGQhEfC0_ltjQNcsIQ
Published: July 18, 2025 21:51
[How to Stop A Bully So He Regrets It | Russian Mafia Advice](https://www.youtube.com/watch?v=d7KUzbmkvQA)
A clever video fronting for for a book advertisement.
urn:x-pdf:8407ad401319d61029ae96fb4e0c7372
https://hypothes.is/a/YE2mlGQgEfCPWWeZ6GhI7w
Published: July 18, 2025 21:44
Thus the gods turn their most favouredChampions into Daemon Princes, and these creaturesscour the mortal realms in turn looking for worthyChampions for their master to recruit or reward.The pyramid scheme never ends.
urn:x-pdf:8407ad401319d61029ae96fb4e0c7372
https://hypothes.is/a/XXNyVmQfEfCphzMRudCu8Q
Published: July 18, 2025 21:37
Boundwithin the metal of the blade, and imprisoned therefor an eternity, is the spirit of a Daemon. The weaponserves only the interests of its Chaos God, reapingsouls for the glory of its master.Presumably expediting the process of soul-harvesting from…
urn:x-pdf:8407ad401319d61029ae96fb4e0c7372
https://hypothes.is/a/GvhVPGQeEfCTEn9MAgisww
Published: July 18, 2025 21:28
So it is that the Daemon Princes of ChaosSo it goes: Marauder, Warrior/Knight, Chosen, Exalted Hero, Champion, Lord, then Daemon Prince. I'm still not sure where 'Champion' fits into the hierarchy, or if it's more of a catch-all term.
urn:x-pdf:8407ad401319d61029ae96fb4e0c7372
https://hypothes.is/a/f1ztPGQcEfCR2gMEwD9ttw
Published: July 18, 2025 21:16
The strangest aspect of these suits is that they bindthemselves to the flesh of their wearer, becomingsomething like a second skin. Once donned, a suit ofChaos Armour may not be removed until death.Furthermore, Chaos Armour is self-repairing, closingrents…
We R Memory Maker Typecast Typewriter Review! (Royal Classic, Royal Epoch)
https://hypothes.is/a/QnatLGQcEfCYSVNOA4lQ8A
Published: July 18, 2025 21:14
[We R Memory Maker Typecast Typewriter Review! (Royal Classic, Royal Epoch)](https://www.youtube.com/watch?v=Vo62Y7cYfE0)
by [[Transcendental Airwaves]]
He's got a mention of where to adjust the on-feet/motion adjustment screws are on the carriage at the…
Chromosomal capture of beneficial genes drives plasmids toward ecological redundancy
https://hypothes.is/a/eRiDPGQNEfCuXg95fEFqmA
Published: July 18, 2025 19:29
Interesting articulation of evolution of beneficial genes from plasmid acquisition to domestication through chromosomal capture.
README
https://hypothes.is/a/I81ilmQLEfCJ3UfNLOvrMA
Published: July 18, 2025 19:12
It is currently aimed at the analysis of metagenomes sequenced using Illumina short read technology.Does this work with long-reads as well?
> (Todd) likely due to indels in long reads and other issues we had to fight with for SeqScreen-Nano etc
Gertrude — Mud Paintings
https://hypothes.is/a/hZnDfmQHEfCFjRuXTa5Q5A
Published: July 18, 2025 18:46
sweet, plain text is working fine :)
Gertrude — Mud Paintings
https://hypothes.is/a/efSycmQHEfCN8vO7H5e6vQ
Published: July 18, 2025 18:46
huzzah!
Blogging
https://hypothes.is/a/q8ajNGQFEfCbEBclQFY54Q
Published: July 18, 2025 18:33
Blogging helps students to work on their online presence and become reflective in their learning as well.I also think this can help students understand the impact of their digital footprint
Blogging
https://hypothes.is/a/c0ABSmQFEfCKnssD2bpqrw
Published: July 18, 2025 18:31
One tip that works well for some is to have a document open throughout the week, and as you have ideas (or a few free minutes) jot them down in the documentI love this idea of journaling throughout the day to have entries to talk about in the blog
Blogging
https://hypothes.is/a/LT9BamQFEfCwGp9zjLRgNg
Published: July 18, 2025 18:29
research suggests that reflecting on teaching practice can lead to improved lesson and learning quality within the classroom.I think reflecting on teaching practices is essential to classroom learning. Self reflection for students is extremely important, I…
Controlled colonization of the human gut with a genetically engineered microbial therapeutic
https://hypothes.is/a/R0JpkGQDEfCd7wvxO-Qb-A
Published: July 18, 2025 18:16
Cool stuff!
Rules for end-of-line hyphens?
https://hypothes.is/a/62__EmQAEfCLY3OuH1c3kA
Published: July 18, 2025 17:59
in olden timey days, they taught more or less like this:
hyphenate between syllables, in general, more than half the word should be on the first line.
If the bell has gone off, then generally don’t start a long word. After the bell, there is room for…
Rules for end-of-line hyphens?
https://hypothes.is/a/yHipRmQAEfC_Je8XebCBpQ
Published: July 18, 2025 17:58
[Rules for end-of-line hyphens?](https://www.reddit.com/r/typewriters/comments/1m2vc8m/rules_for_endofline_hyphens/)
by u/Heavyduty35
Back in the heyday of typewriters in the office books like Dougherty's Instant Spelling Dictionary were kept on the desks…
Are AI’s Promises of Productivity Worth the Risks for Pastors? - 9Marks
https://hypothes.is/a/9_7w_mP_EfCLcqdBa0y6JA
Published: July 18, 2025 17:52
atrophy through dependency is one issue that is unique to AI.Very good point!
YouTube
https://hypothes.is/a/oeDr-mP_EfCLPKtddW4a7g
Published: July 18, 2025 17:50
Ватикан, код Давични
и массоны.
Ватикан как главное место,
где хранятся самые страшыне тайны человечеста
How can you tell when someone has real potential in pure mathematics?
https://hypothes.is/a/EVW_1GP_EfCh7duCi1kjdA
Published: July 18, 2025 17:46
How can you tell when someone has real potential in pure mathematics?question by u/OkGreen7335 at https://reddit.com/r/math/comments/1m0qe7f/how_can_you_tell_when_someone_has_real_potential/
The same way the music teacher in Liverpool who had half of The…
Carbon 14 - an overview | ScienceDirect Topics
https://hypothes.is/a/ZuvVfmP-EfCxoR_qj5U33Q
Published: July 18, 2025 17:41
Taking all anthropogenic sources into account, a global average specific activity of modern carbon is now 13.56 ± 0.07 dpm/g C. In §5.8.1 we discuss dating by the “C14-method”,C-14 decay rate today
Carbon 14 - an overview | ScienceDirect Topics
https://hypothes.is/a/Sf3C2GP-EfCt52uNM2VJgw
Published: July 18, 2025 17:40
14C is produced in the atmosphere by a variety of reactions, the most important being between thermalized neutrons from cosmic radiation and nitrogen atoms:(5.2)n(slow)+14N→14C+1HThis reaction occurs with a yield of approximately 22 000 atoms 14C formed…
Stability and comparability of meritocratic beliefs in school-age students: A measurement invariance approach across time and cohorts
https://hypothes.is/a/NCzt9mPxEfCtXUNQdKjPyQ
Published: July 18, 2025 16:06
MeasuresTengo que agregar acá la variable de cohort_level, la freq, M y SD de la edad y el sexo agrupando por cohorte
Stability and comparability of meritocratic beliefs in school-age students: A measurement invariance approach across time and cohorts
https://hypothes.is/a/F21kAmPxEfCScHNstu39Wg
Published: July 18, 2025 16:05
1.1Agregaría en el background algo sobre contexto chileno, ya sea una subsección o ir nutriendo lo que ya está con evidencia desde Chile y explicando el contexto del mercado educativo, para que tenga más sentido.
International Chemical Identifier
https://hypothes.is/a/oRhKxGPwEfCtfiuSmLzS-w
Published: July 18, 2025 16:02
Stereochemical layer
double bonds and cumulenes (prefix: "b")
tetrahedral stereochemistry of atoms and allenes (prefixes: "t", "m")
type of stereochemistry information (prefix: "s")sterochemical layer of inchi
Citizen-Sensing-A-Toolkit.pdf
https://hypothes.is/a/WvRgtGPwEfCh1NcFyRJN9A
Published: July 18, 2025 16:00
From urban noise pollution totemperature, humidity and light inrural environments, the issues at thecore of each Barcelona pilot were verydifferent. Accordingly, we recheck this out
US History in 15 Foods
https://hypothes.is/a/PBWkqmPwEfCvPSumEjmwHQ
Published: July 18, 2025 15:59
Enslaved people onthese ships often used the refusal of food as a tool of resistance, subjectingthemselves to starvation or throwing themselves overboard to escape theirbondageResistance against enslavers
US History in 15 Foods
https://hypothes.is/a/BMZCemPwEfCq9kfCXEaAXg
Published: July 18, 2025 15:58
When enslaved people drank potlikker, ate greens, or sopped up the liquidwith corn pone, they were carrying on a long and storied food tradition thatthey and their ancestors brought with them from different parts of the AfricancontinentTraditions, sense of…
US History in 15 Foods
https://hypothes.is/a/PG9_qGPvEfCF5gcfwxjOpA
Published: July 18, 2025 15:52
Potlikker embodies many elements of the story of food in enslavement.Potlikker associates with enslavements
Considered nutritious and is welcome in enslaved people's diet
US History in 15 Foods
https://hypothes.is/a/DqhJvGPtEfCJuWMroeZpaw
Published: July 18, 2025 15:37
At the turn of the nineteenth century, the United States was still a veryyoung nation, reconfiguring itself in response to new ideas and new leaders.Political changes- probably resistance after the Whiskey Rebellion
US History in 15 Foods
https://hypothes.is/a/91MWTmPrEfC3bI9lJhb4hg
Published: July 18, 2025 15:29
This was a time of dietary excess, to which Graham was reacting.Dietary reforms- probably around the Industrial Revolution cause it produced too much food for people to consume.
view
https://hypothes.is/a/wg6MZmPrEfCLg6uyQsb4QA
Published: July 18, 2025 15:27
A trusting and collaborative relationship between the board and superintendentThis would mean that the superintendent has a collaborative and trusting relationship with staff. In order for the district to be effective trusting and collaborative…
view
https://hypothes.is/a/ahPAWGPrEfCU4O-taiFjng
Published: July 18, 2025 15:25
clear that school boards in high-achieving districts holda high, shared vision about the capabilities of both students and staff—I am sure in low achieving schools the board, administration and staff have the same visions however outside factors might be…
US History in 15 Foods
https://hypothes.is/a/MbKeoGPrEfCq63ebQJGqyg
Published: July 18, 2025 15:23
Graham’s work embodies the United States of the early nineteenth century.It was a time of widening if still limited democracy, of political upheaval, a timeof national expansion and technological innovation, of religious ferment andpublic health reform,…
US History in 15 Foods
https://hypothes.is/a/2DuKOmPqEfCl489oeohqjQ
Published: July 18, 2025 15:21
As rum consumption continued to decline with the banon the international slave trade in the early 1800s, whiskey became the mostpopular and cheapest alcoholic drink. The period between the 1790s and the1820s saw Americans drinking more alcohol overall than…
US History in 15 Foods
https://hypothes.is/a/n1fctGPqEfC7PVdfqjgC2A
Published: July 18, 2025 15:19
Whiskey mattered, butnot because the frontiersmen were hillbillies obsessed with getting drunk.As this chapter has illustrated, whiskey mattered because it facilitated trade.Whiskey facilitated trade, Whiskey rebellion --> survival, sense of identity (?)
tRNA genes rapidly change in evolution to meet novel translational demands
https://hypothes.is/a/6y8GDmPpEfCl33c7bNZa9A
Published: July 18, 2025 15:14
To demonstrate the importance of the balance between codon usage and the cellular tRNA pool we created a yeast strain in which the single copy of the arginine tRNA gene, tR(CCU)J, was deleted (designated ΔtRNAArgCCU). Consequently, in this deletion strain,…
tRNA genes rapidly change in evolution to meet novel translational demands
https://hypothes.is/a/vcQWMmPpEfCTdp-5yampng
Published: July 18, 2025 15:13
tRNAs constitute a fundamental component in the process of translation, linking codons to their corresponding amino acids (Widmann et al., 2010). tRNA genes are classified into gene families according to their anticodon, with each gene family containing…
The heterogeneity of dermal mesenchymal cells reproduced in skin equivalents regulates barrier function and elasticity
https://hypothes.is/a/pY9tUGPpEfCQUOvIYiby5g
Published: July 18, 2025 15:12
**Note:** This preprint has been reviewed by subject experts for *Review Commons*. Content has not been altered except for formatting.
Learn more at [Review Commons](https://reviewcommons.org)
-----
### Referee \#4
#### Evidence, reproducibility and…
The heterogeneity of dermal mesenchymal cells reproduced in skin equivalents regulates barrier function and elasticity
https://hypothes.is/a/pWQknGPpEfCTda_I-QrqSA
Published: July 18, 2025 15:12
**Note:** This preprint has been reviewed by subject experts for *Review Commons*. Content has not been altered except for formatting.
Learn more at [Review Commons](https://reviewcommons.org)
-----
### Referee \#3
#### Evidence, reproducibility and…
The heterogeneity of dermal mesenchymal cells reproduced in skin equivalents regulates barrier function and elasticity
https://hypothes.is/a/pcJsyGPpEfCl3SfD6XNzaQ
Published: July 18, 2025 15:12
**Note:** This response was posted by the corresponding author to *Review Commons*. The content has not been altered except for formatting.
Learn more at [Review Commons](https://reviewcommons.org)
-----
### Reply to the reviewers
__*Reviewer #1*__
…
The heterogeneity of dermal mesenchymal cells reproduced in skin equivalents regulates barrier function and elasticity
https://hypothes.is/a/pRgWkmPpEfCwLMNojo2Ymg
Published: July 18, 2025 15:12
**Note:** This preprint has been reviewed by subject experts for *Review Commons*. Content has not been altered except for formatting.
Learn more at [Review Commons](https://reviewcommons.org)
-----
### Referee \#2
#### Evidence, reproducibility and…
JavaScript Builder Design Pattern
https://hypothes.is/a/s0Uh6GPUEfCziS_E-td00A
Published: July 18, 2025 12:42
AbstractBuilder is not used because JavaScript does not support abstract classesSure it does.
Impacts of Structural Properties of Myosin II Filaments on Force Generation
https://hypothes.is/a/r8rdgmPUEfCJDeOoQjT9nQ
Published: July 18, 2025 12:42
**Reviewer #1 (Public review):**
Summary:
This work by Ding et al uses agent-based simulations to explore the role of the structure of molecular motor myosin filaments in force generation in cytoskeletal structures. The focus of the study is on…
Impacts of Structural Properties of Myosin II Filaments on Force Generation
https://hypothes.is/a/r_NlImPUEfCWMvusWJcCvQ
Published: July 18, 2025 12:42
**eLife Assessment**
The authors present a useful agent-based model to study the tensile force generated by myosin mini-filaments in actin systems (bundles and networks); by numerically solving a mechanical model of myosin-II filaments, the authors…
Impacts of Structural Properties of Myosin II Filaments on Force Generation
https://hypothes.is/a/r3SVOmPUEfCpb_cTxjW-cA
Published: July 18, 2025 12:42
**Author response:**
The following is the authors’ response to the original reviews
> **Public Reviews:**
>
> **Reviewer #1 (Public review):**
>
> Summary:
>
> This work by Ding et al uses agent-based simulations to explore the role of the structure…
Impacts of Structural Properties of Myosin II Filaments on Force Generation
https://hypothes.is/a/r6B97mPUEfChsx9xdspouQ
Published: July 18, 2025 12:42
**Reviewer #2 (Public review):**
Summary:
In this study, the authors use a mechanical model to investigate how the geometry and deformations of myosin II filaments influence their force generation. They introduce a force generation efficiency…
Synaptic Encoding of Time in Working Memory
https://hypothes.is/a/c4SXUGPUEfCo7I9yM_1LIw
Published: July 18, 2025 12:40
**Reviewer #1 (Public review):**
Summary:
The issue of how the brain can maintain the serial order of presented items in working memory is a major unsolved question in cognitive neuroscience. It has been proposed that this serial order maintenance…
Synaptic Encoding of Time in Working Memory
https://hypothes.is/a/c7Q1CmPUEfC-4ReUoy240g
Published: July 18, 2025 12:40
**eLife Assessment**
This valuable manuscript addresses the longstanding question of how the brain maintains serial order in working memory, proposing a biologically grounded model based on synaptic augmentation mechanisms that operates on longer time…
Synaptic Encoding of Time in Working Memory
https://hypothes.is/a/c1PHsGPUEfCcyGtBuUwmPQ
Published: July 18, 2025 12:40
**Reviewer #2 (Public review):**
In this manuscript, the authors present a model to explain how working memory (WM) encodes both existence and timing simultaneously using transient synaptic augmentation. A simple yet intriguing idea.
The model…
Synaptic Encoding of Time in Working Memory
https://hypothes.is/a/cyOrcGPUEfCrcudJUAzoaA
Published: July 18, 2025 12:40
**Author response:**
> **Reviewer #1 (Public Review):**
> (1) The network they propose is extremely simple. This simplicity has pros and cons: on the one hand, it is nice to see the basic phenomenon exposed in the simplest possible setting. On the other…
https://www.biorxiv.org/lookup/doi/10.1101/2024.10.07.616413
https://hypothes.is/a/d-2p-mPSEfC-36ugalfxaA
Published: July 18, 2025 12:26
Version 2 of this preprint has been **peer-reviewed and recommended by [Peer Community in Ecology](https://ecology.peercommunityin.org/)**.
See [the peer reviews and the recommendation](https://doi.org/10.24072/pci.ecology.100764).
Tőzsdei megbízás - ClavisNXT
https://hypothes.is/a/_igjlGPQEfC6k3eUP774-g
Published: July 18, 2025 12:16
Kész. Kivettem mindegyik tranzakciós leírásból és a Tranzakció Általános leírásból.
Kivéve ezt a mondatot: A Tranzakciók/Megbízás menüpontban az Ügyfél tranzakciók aloldalon Új tranzakció létrehozása gombbal rögzíthető.
Azért, mert a Bundle tranzakció…
Bloomberg - ClavisNXT
https://hypothes.is/a/g4S8EGPQEfChrls82eXSzg
Published: July 18, 2025 12:12
Kész. Zsófi javította.
The evolution of interdisciplinarity and internationalization in scientific journals
https://hypothes.is/a/ci6wyGPMEfCAKX9n5BF_OQ
Published: July 18, 2025 11:43
**eLife Assessment**
This important study uses data on over 56 million articles to examine the dynamics of interdisciplinarity and international collaborations in research journals. The data analytics used to quantify disciplinary and national…
The evolution of interdisciplinarity and internationalization in scientific journals
https://hypothes.is/a/cdQxtmPMEfCKXruoTRkDDw
Published: July 18, 2025 11:43
**Reviewer #2 (Public review):**
Summary:
This paper uses large-scale publication data to examine the dynamics of interdisciplinarity and international collaborations in research journals. The main finding is that interdisciplinarity and…
The evolution of interdisciplinarity and internationalization in scientific journals
https://hypothes.is/a/cgJ7NGPMEfC1Ru8lZl8myQ
Published: July 18, 2025 11:43
**Reviewer #1 (Public review):**
Summary:
The authors aim to explore how interdisciplinarity and internationalization-two increasingly prominent characteristics of scientific publishing-have evolved over the past century. By constructing…
Single neurons detect spatiotemporal activity transitions through STP and EI imbalance
https://hypothes.is/a/sJW6EGPLEfCPr8tSQhaabw
Published: July 18, 2025 11:38
**Reviewer #1 (Public review):**
Summary:
This study uses optogenetics to activate CA3, while recording from CA1 neurons and characterizing the excitation/inhibition (E/I) balance. They observe use-dependent alterations in the E/I balance as a…
Single neurons detect spatiotemporal activity transitions through STP and EI imbalance
https://hypothes.is/a/sMMwOmPLEfCO6Ld6kW-H-A
Published: July 18, 2025 11:38
**eLife Assessment**
This useful study examines excitation/inhibition (E/I) balance in the CA3-CA1 circuit of the hippocampus. Experimental and computational modeling results are presented, but these results provide incomplete evidence to support the…
Single neurons detect spatiotemporal activity transitions through STP and EI imbalance
https://hypothes.is/a/sDkJlmPLEfC5Ud_Nz73g4Q
Published: July 18, 2025 11:38
**Reviewer #3 (Public review):**
Summary:
This work shows experimentally and computationally that single CA1 neurons can perform mismatch detection on patterned CA3 inputs and that STP and EI balance underlie this detection.
Strengths:
…
Single neurons detect spatiotemporal activity transitions through STP and EI imbalance
https://hypothes.is/a/sGkNCGPLEfC1mcc8vb3_wQ
Published: July 18, 2025 11:38
**Reviewer #2 (Public review):**
Summary:
The authors investigate EI balance in the CA3-CA1 projections, emphasizing synaptic depletion and the implied rebalancing of excitatory and inhibitory projections onto a single CA1 Pyramidal cell. They…
Quantifying Intracellular Mechanosensitive Response upon Spatially Defined Mechano-Chemical Triggering
https://hypothes.is/a/gQ7MumPKEfCUANNu4BZWpA
Published: July 18, 2025 11:29
**eLife Assessment**
This valuable study provides evidence that the integration of the nuclear envelope into the endoplasmic reticulum provides a mechanism for mechanical integration across this continuous membrane system. If robustly demonstrated,…
Glossary
https://hypothes.is/a/PQo4omO6EfCvy2P3QTK4Wg
Published: July 18, 2025 09:33
Địa Chỉ Thu Mua Phế Liệu Tại Bình Dương Uy Tín
https://hypothes.is/a/f9Y9WGO5EfCT9O_l0wsi5g
Published: July 18, 2025 09:28
Chúng tôi thu mua đa dạng các loại vật liệu:
Phế liệu kim loại : sắt, đồng, nhôm, inox,…
Phế liệu phi kim loại : thùng carton, giấy, nhựa, linh kiện điện tử,…
Phế liệu công nghiệp khác : pallet gỗ, hàng lỗi, vải xốp, bao bì,…
Với hơn 10 năm kinh…
Dual transcranial electromagnetic stimulation of the precuneus-hippocampus network boosts human long-term memory
https://hypothes.is/a/7DN3qmOzEfCgj1PXnsGQoA
Published: July 18, 2025 08:48
**eLife Assessment**
This work presents potentially important findings suggesting that a combination of transcranial stimulation approaches applied for a short period could improve memory performance. However, the evidence supporting the conclusions…
Dual transcranial electromagnetic stimulation of the precuneus-hippocampus network boosts human long-term memory
https://hypothes.is/a/7AQ2tmOzEfChm7OI3OiFXQ
Published: July 18, 2025 08:48
**Review #1 (Public Review):**
Summary:
The authors employ a combination of repetitive transcranial magnetic stimulation (intermittent theta burst-iTBS) and transcranial alternating current stimulation (gamma tACS) as an approach aimed to improve memory…
Dual transcranial electromagnetic stimulation of the precuneus-hippocampus network boosts human long-term memory
https://hypothes.is/a/66Ac7mOzEfCLJsul0a95sw
Published: July 18, 2025 08:48
**Reviewer #3 (Public review):**
Summary:
Borghi and colleagues present results from 4 experiments aimed at investigating the effects of dual γtACS and iTBS stimulation of the precuneus on behavioral and neural markers of memory formation. In their first…
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