Concise synthesis of chiral tricyclic γ-lactams via synergistic isothiourea/Ir catalyzed asymmetric [3 + 2] annulation
https://www.nature.com/articles/s41467-025-67390-4
Published: December 7, 2025 00:00
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<p><em>Nature Communications</em> is an open access, multidisciplinary journal dedicated to publishing high-quality research in all areas of the biological, health, physical, chemical and Earth sciences. Papers published by the journal aim to represent important advances of significance to specialists within each field.</p> <p>We are committed to providing an efficient service for both authors and readers. Our team of independent editors make rapid and fair publication decisions. Prompt dissemination of accepted papers to a wide readership and beyond is achieved through a programme of continuous online publication. </p>
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Concise synthesis of chiral tricyclic γ-lactams via synergistic isothiourea/Ir catalyzed asymmetric [3 + 2] annulation
https://www.nature.com/articles/s41467-025-67390-4
Published: December 7, 2025 00:00
Tissue-resident microbiota impacts colorectal cancer progression and prognosis
https://www.nature.com/articles/s41467-025-67047-2
Published: December 7, 2025 00:00
CASSIA: a multi-agent large language model for automated and interpretable cell annotation
https://www.nature.com/articles/s41467-025-67084-x
Published: December 7, 2025 00:00
Vinyloxy radicals unveiled as critical intermediates in Ni/La2O3-catalyzed ethanol steam reforming for hydrogen production
https://www.nature.com/articles/s41467-025-67170-0
Published: December 7, 2025 00:00
INSM1 governs a neuronal progenitor state that drives glioblastoma in a human stem cell model
https://www.nature.com/articles/s41467-025-66371-x
Published: December 7, 2025 00:00
EP300 deficiency leads to chronic replication stress mediated by defective replication fork protection
https://www.nature.com/articles/s41467-025-67171-z
Published: December 7, 2025 00:00
Multichannel, ultra-wideband Rydberg electrometry with an optical frequency comb
https://www.nature.com/articles/s41467-025-64439-2
Published: December 7, 2025 00:00
Molecular competition induced Janus hydrogel bioelectronic interface for electroceutical modulation
https://www.nature.com/articles/s41467-025-67143-3
Published: December 7, 2025 00:00
Worldwide trends in metabolic syndrome from 2000 to 2023: a systematic review and modelling analysis
https://www.nature.com/articles/s41467-025-67268-5
Published: December 6, 2025 00:00
Targeting TNK2/ACK1 reverses the immunosuppressive tumor microenvironment and synergizes with immunochemotherapy in pancreatic cancer
https://www.nature.com/articles/s41467-025-67197-3
Published: December 6, 2025 00:00
Lipid dependence of connexin-32 gap junction channel conformations
https://www.nature.com/articles/s41467-025-67004-z
Published: December 5, 2025 00:00
Complexity of quantum tomography from genuine non-Gaussian entanglement
https://www.nature.com/articles/s41467-025-67062-3
Published: December 5, 2025 00:00
Bone homeostasis regulation by in vivo generation of osteoclast-derived apoptotic bodies using targeted self-assembly
https://www.nature.com/articles/s41467-025-66791-9
Published: December 5, 2025 00:00
Discovery of a small molecule TLR3 agonist adjuvant
https://www.nature.com/articles/s41467-025-66878-3
Published: December 4, 2025 00:00
Non-small cell lung cancer molecular subtypes and vulnerability to immunotherapy treatment combinations
https://www.nature.com/articles/s41467-025-66803-8
Published: December 3, 2025 00:00
Metagenomic sequencing enables accurate pathogen and antimicrobial susceptibility profiling in complicated UTIs in approximately four hours
https://www.nature.com/articles/s41467-025-66865-8
Published: December 3, 2025 00:00
Mechanically-robust and humidity-tunable self-destructive polymers enabled by hydrogen-bond nanoconfinement
https://www.nature.com/articles/s41467-025-66044-9
Published: December 3, 2025 00:00
Tensile strain regulation via grain boundary buffering for flexible perovskite solar cells
https://www.nature.com/articles/s41467-025-67027-6
Published: December 2, 2025 00:00
An ammonia-induced universal synthesis approach for manganese based layered oxides
https://www.nature.com/articles/s41467-025-66960-w
Published: December 2, 2025 00:00
Renal insulin-like growth factor binding-protein 7 is a critical promoter of progressive diabetic kidney disease
https://www.nature.com/articles/s41467-025-66490-5
Published: December 1, 2025 00:00
PyFuRNAce: an integrated design engine for RNA origami
https://www.nature.com/articles/s41467-025-66290-x
Published: December 1, 2025 00:00
Recyclable quasi-solid-state dynamic windows via reversible dual-metal electrodeposition for building energy modulation
https://www.nature.com/articles/s41467-025-66963-7
Published: December 1, 2025 00:00
Emergence of alternative states in a synthetic human gut microbial community
https://www.nature.com/articles/s41467-025-67036-5
Published: December 1, 2025 00:00
Dietary lipid content modifies wah-1/AIFM1-associated phenotypes via LRK-1 and DRP-1 expression in C. elegans
https://www.nature.com/articles/s41467-025-66900-8
Published: December 1, 2025 00:00
THRAP3 promotes ferroptosis resistance in acute myelocytic leukemia through SLU7-mediated alternative splicing of GIT2
https://www.nature.com/articles/s41467-025-66931-1
Published: December 1, 2025 00:00
MYC drives left-handed Z-DNA formation to shape gene expression
https://www.nature.com/articles/s41467-025-66886-3
Published: December 1, 2025 00:00
TMEM145 is a key stereociliary component in the link structures of outer hair cells and mediates the secretion of stereocilin and tubby
https://www.nature.com/articles/s41467-025-67011-0
Published: December 1, 2025 00:00