Senescent cells cluster CTCF on nuclear speckles to instruct an alternative splicing program
https://www.nature.com/articles/s43587-026-01171-6
Published: July 21, 2026 00:00
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How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the connection between aging and disease? Can we predict the evolving trends in the aging of human populations and prepare our societies for what has been called the Silver Tsunami? These are some of the important questions that the broad field of aging research is trying to address and that together form one of the Grand Challenges of the twenty-first century. The mission of Nature Aging is to provide a unique multidisciplinary, unifying and highly visible publishing platform for the aging-research community. The journal is highly selective yet broad in its coverage, publishing research from across the entire spectrum of the field, ranging from the basic biology of aging to the impact of aging on society. The journal aims to foster interactions among different areas of this diverse field of research and to promote new and exciting ideas within and beyond the research community, to enable synergy and maximize scientific and societal impact.
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Senescent cells cluster CTCF on nuclear speckles to instruct an alternative splicing program
https://www.nature.com/articles/s43587-026-01171-6
Published: July 21, 2026 00:00
Positioning TERT at the apex of aging
https://www.nature.com/articles/s43587-026-01179-y
Published: July 20, 2026 00:00
Plasma proteome profiling identified biomarkers for the differential diagnosis and molecular staging of neurodegenerative dementias
https://www.nature.com/articles/s43587-026-01162-7
Published: July 20, 2026 00:00
Disruption of CDK4/6–RARα–NF-κB axis attenuates senescence-associated inflammation and improves function during aging and following chemotherapy
https://www.nature.com/articles/s43587-026-01168-1
Published: July 17, 2026 00:00
Trained immunity links hematopoietic stem cell aging to aging-associated inflammation
https://www.nature.com/articles/s43587-026-01175-2
Published: July 16, 2026 00:00
Spatiotemporal dynamics of tau extent and load increase in Alzheimer’s disease across four longitudinal cohorts
https://www.nature.com/articles/s43587-026-01143-w
Published: July 14, 2026 00:00
Mapping and manipulating aged and senescent microglia
https://www.nature.com/articles/s43587-026-01167-2
Published: July 13, 2026 00:00
Spatial mapping and senolytic targeting of senescent and disease-associated microglia in aged mouse brain white matter
https://www.nature.com/articles/s43587-026-01154-7
Published: July 13, 2026 00:00
Author Correction: A Treg-specific long noncoding RNA maintains immune-metabolic homeostasis in aging liver
https://www.nature.com/articles/s43587-026-01184-1
Published: July 9, 2026 00:00