Aberrant engagement of P-selectin drives hematopoietic stem cell aging in mice
https://www.nature.com/articles/s43587-025-00880-8
Published: May 23, 2025 00:00
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How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the connection between aging and disease? Can we predict the evolving trends in the aging of human populations and prepare our societies for what has been called the Silver Tsunami? These are some of the important questions that the broad field of aging research is trying to address and that together form one of the Grand Challenges of the twenty-first century. The mission of Nature Aging is to provide a unique multidisciplinary, unifying and highly visible publishing platform for the aging-research community. The journal is highly selective yet broad in its coverage, publishing research from across the entire spectrum of the field, ranging from the basic biology of aging to the impact of aging on society. The journal aims to foster interactions among different areas of this diverse field of research and to promote new and exciting ideas within and beyond the research community, to enable synergy and maximize scientific and societal impact.
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Aberrant engagement of P-selectin drives hematopoietic stem cell aging in mice
https://www.nature.com/articles/s43587-025-00880-8
Published: May 23, 2025 00:00
Activation of AMPK by GLP-1R agonists mitigates Alzheimer-related phenotypes in transgenic mice
https://www.nature.com/articles/s43587-025-00869-3
Published: May 20, 2025 00:00
Large-scale plasma proteomic profiling unveils diagnostic biomarkers and pathways for Alzheimer’s disease
https://www.nature.com/articles/s43587-025-00872-8
Published: May 20, 2025 00:00
GLP-1R agonists protect against Alzheimer’s disease by rewiring energy regulation
https://www.nature.com/articles/s43587-025-00881-7
Published: May 20, 2025 00:00
Targeting the chromatin remodeler BAZ2B mitigates hepatic senescence and MASH fibrosis
https://www.nature.com/articles/s43587-025-00862-w
Published: May 19, 2025 00:00
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration
https://www.nature.com/articles/s43587-025-00878-2
Published: May 16, 2025 00:00
Ancient viruses sustain mammalian reproduction
https://www.nature.com/articles/s43587-025-00867-5
Published: May 14, 2025 00:00
Reference centiles for intrinsic capacity to monitor clinical health outcomes in real-world primary care cohorts
https://www.nature.com/articles/s43587-025-00861-x
Published: May 13, 2025 00:00
Gut microbiota-dependent increase in phenylacetic acid induces endothelial cell senescence during aging
https://www.nature.com/articles/s43587-025-00864-8
Published: May 12, 2025 00:00
Author Correction: Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer
https://www.nature.com/articles/s43587-025-00892-4
Published: May 12, 2025 00:00
Stem cell therapies for Parkinson’s disease
https://www.nature.com/articles/s43587-025-00885-3
Published: May 9, 2025 00:00
Replacement as an aging intervention
https://www.nature.com/articles/s43587-025-00858-6
Published: May 8, 2025 00:00
Recycling tRNA fragment ‘trash’ into treasure
https://www.nature.com/articles/s43587-025-00870-w
Published: May 5, 2025 00:00
Quasi-spatial single-cell transcriptome based on physical tissue properties defines early aging associated niche in liver
https://www.nature.com/articles/s43587-025-00857-7
Published: May 5, 2025 00:00
Life-course approaches are needed to foster equitable healthy aging
https://www.nature.com/articles/s43587-025-00875-5
Published: May 2, 2025 00:00