RSS Parrot

https://bsky.app/profile/erictopol.bsky.social/post/3lpwbmvkvms22

Published: May 24, 2025 13:43

"I have no time to sit too long. I'm happier when I can produce something."—Lee Rushall, age 98, a Super Ager In Chasing Life w/ Sanjay Gupta @cnn.com w/transcript…

https://bsky.app/profile/erictopol.bsky.social/post/3lpudpdgj5s2a

Published: May 23, 2025 19:15

Excess deaths in the US vs other high-income countries. Coming down relative to prior US data but still the outlier …

https://bsky.app/profile/erictopol.bsky.social/post/3lpttglznw22j

Published: May 23, 2025 14:23

A pill for sleep apnea that keeps the airway open…

https://bsky.app/profile/erictopol.bsky.social/post/3lprzqhpji22z

Published: May 22, 2025 21:11

p-tau217 and other biomarkers for Alzheimer’s disease also tracked with loss of muscle strength in ~2,000 participants followed 12 years (Figures hand grip and chair-to-stand) Suggests Brain-to-Muscle bidirectional axis …

https://bsky.app/profile/erictopol.bsky.social/post/3lpri4gx6ss2v

Published: May 22, 2025 15:56

Experimental evidence that post-stress sleep has the capacity to build resilience https://cell.com/neuron/fulltext/S0896-6273(25)00311-3

https://bsky.app/profile/erictopol.bsky.social/post/3lprhctfn2225

Published: May 22, 2025 15:41

Good cover @economist.com

https://bsky.app/profile/erictopol.bsky.social/post/3lpp47pf5sk2n

Published: May 21, 2025 17:17

New @nature.com An ingenious way to track DNA replication patterns at the single-cell level that leads to cell heterogeneity and daughter cells that can potentially give rise to cancer https://www.nature.com/articles/s41586-025-08986-0#MOESM8

https://bsky.app/profile/erictopol.bsky.social/post/3lpozqoymks27

Published: May 21, 2025 16:33

Join us today @scripps.edu. Meet my patient Mrs. L.R., featured in Super Agers Link:…

https://bsky.app/profile/erictopol.bsky.social/post/3lpowwxpn5s2b

Published: May 21, 2025 15:43

Less sedentary time among American adults https://jamanetwork.com/journals/jama/fullarticle/2834380

https://bsky.app/profile/erictopol.bsky.social/post/3lpotq54umc2j

Published: May 21, 2025 14:45

On social engagement and healthy aging. open-access "High social engagement was associated with lower mortality risk than low engagement (a-HR:0.58) https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.19511

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Published: May 21, 2025 14:40

Good news: Major discoveries, persistent disruptions in science are on the rise https://www.nature.com/articles/s43588-025-00808-7 https://www.nature.com/articles/d41586-025-01548-4…

https://bsky.app/profile/erictopol.bsky.social/post/3lpnciyojdk2x

Published: May 21, 2025 00:05

The risk of sudden cardiac death among male bodybuilders https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehaf285/8131432

https://bsky.app/profile/erictopol.bsky.social/post/3lpmzimxdv22c

Published: May 20, 2025 21:23

Tracking consumption of ultra-processed foods via metabolites in blood or urine https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1004560

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Published: May 20, 2025 14:01

Our ability to accurately predict #Alzheimer's disease years in advance of any symptoms keeps getting better with plasma proteins and A.I. analytics @nataging.nature.com https://www.nature.com/articles/s43587-025-00872-8

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Published: May 19, 2025 22:36

Glycemic control among people with Type 2 diabetes linked to modestly reduced cognitive performance…

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Published: May 19, 2025 13:51

Today the 1st case of CRISPR 3.0 (Prime genome editing) announced for a teenager with chronic granulomatous disease https://www.nature.com/articles/d41586-025-01593-z [contains quote post or other embedded content]

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Published: May 18, 2025 21:32

How Type 2 diabetes leads to blood vessel dysfunction and sequelae related to this adverse effect @jclinical-invest.bsky.social https://jci.org/articles/view/193128

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Published: May 18, 2025 18:06

My frank conversation with @realdoctormike.bsky.social about longevity, supplements, extending healthspan, and the science of aging https://www.youtube.com/watch?v=EBAwZLxs_OE

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Published: May 18, 2025 14:37

This week's genome editing triumph is a big deal. Here's why https://erictopol.substack.com/p/the-first-human-to-undergo-in-vivo

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Published: May 17, 2025 13:50

We can build on this. It doesn't require reversing aging. It's the theme of SUPER AGERS. GIft link https://www.wsj.com/health/wellness/americans-in-their-80s-and-90s-are-redefining-old-age-5f8ae8a6?st=yjjjU6&reflink=desktopwebshare_permalink

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Published: May 16, 2025 20:52

Another example of opportunistic A.I. applied to medical imaging. @ai.nejm.org Quantifying coronary artery calcium score from chest CT (nongated, not performed for this purpose) https://ai.nejm.org/doi/full/10.1056/AIoa2400937

https://bsky.app/profile/erictopol.bsky.social/post/3lpcskvyldk22

Published: May 16, 2025 19:53

On finding treatments for #LongCovid “What’s so sad here is people are so desperate, and we don’t have anything [of so many solid candidates] validated." gift link:…

https://bsky.app/profile/erictopol.bsky.social/post/3lpcqszklxk27

Published: May 16, 2025 19:21

There is remarkable extent of bi-directional cross-talk between the nervous system and Type 2 immunity (vs infectious parasites, allergens, irritants, and toxins). A new and superb review @sciimmunology.bsky.social …

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Published: May 16, 2025 15:53

The link between high quality carbohydrates and dietary fiber with healthy aging …

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Published: May 16, 2025 14:38

No it Won't and No It Isn't. https://www.popularmechanics.com/science/health/a64781298/can-ai-double-human-lifespan/

https://bsky.app/profile/erictopol.bsky.social/post/3lpc7hs6ovk2y

Published: May 16, 2025 14:11

Another example of opportunistic A.I. applied to medical imaging. Quantifying coronary artery calcium score from chest CT (nongated, not performed for this purpose) https://ai.nejm.org/doi/full/10.1056/AIoa2400937

https://bsky.app/profile/erictopol.bsky.social/post/3lpc53r66p22h

Published: May 16, 2025 13:28

“Americans die earlier and are sicker than people in other high-income countries. This has been true for a long time, and the trend is getting worse.” gift link…

https://bsky.app/profile/erictopol.bsky.social/post/3lpa7lyswvk23

Published: May 15, 2025 19:08

I thought I was an "infovore" but then I met the real deal: Tyler Cowen https://erictopol.substack.com/p/tyler-cowen-the-prototypic-polymath

https://bsky.app/profile/erictopol.bsky.social/post/3lpa6kdcdyk2i

Published: May 15, 2025 18:49

Astrocytes have long been conceived as passive support player cells in the brain. But today @science.org (via 3 reports) they got a big upgrade for their active role in neuromodulation and control of brain function…

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Published: May 15, 2025 18:05

Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism" —the 1st human to undergo custom genome editing —from decades of NIH funded research https://www.nejm.org/doi/full/10.1056/NEJMe2505721…

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Published: May 15, 2025 16:02

This is ridiculous and reflects how the longevity craze is out of control "The new bill was drafted and lobbied for by people interested in extending human lifespans—a group of longevity enthusiasts that includes scientists, libertarians, and influencers."…

https://bsky.app/profile/erictopol.bsky.social/post/3lp7sbrbu3k2l

Published: May 15, 2025 15:10

Our A.I. times ;-)

https://bsky.app/profile/erictopol.bsky.social/post/3lp57lp7m222g

Published: May 14, 2025 14:30

My conversation with Vijay Pande on promoting healthy aging https://app.magellan.ai/listen_links/Super_Agers

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Published: May 14, 2025 14:18

What, if anything, is OK for A.I. to write of science papers? feature @nature.com https://nature.com/articles/d41586-025-01463-8

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Published: May 14, 2025 13:39

Some quick book bites from SUPER AGERS on healthspan science @nextbigidea.bsky.social https://nextbigideaclub.com/magazine/5-revolutionary-findings-longevity-science-bookbite/55485/

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Published: May 14, 2025 13:32

How Claude helped a patient "A.I. isn’t a magic bullet. But it uncovers hidden connections in data at speeds no human can match, freeing doctors to focus on what they do best: care." gift link…

https://bsky.app/profile/erictopol.bsky.social/post/3lp3wwuczks2w

Published: May 14, 2025 02:22

So this is MAHA??? https://www.washingtonpost.com/climate-environment/2025/05/13/epa-pfas-drinking-water-rule/?utm_source=alert&utm_medium=email&utm_campaign=wp_news_alert_revere&location=alert

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Published: May 13, 2025 15:40

What do we know about creatine as a supplement? gift link https://www.wsj.com/health/wellness/creatine-health-fitness-benefits-63cdff4f?st=A9Labc&reflink=desktopwebshare_permalink

https://bsky.app/profile/erictopol.bsky.social/post/3lp2pbzahu225

Published: May 13, 2025 14:33

New ways/data to dial the immune system up or down —Probiotics to increase Treg cells, potential adjunct for multiple sclerosis and autoimmune diseases https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00187-2/fulltext —NK cells for cancer…

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Published: May 13, 2025 13:30

In today's @nytimes.com "If they're hawking a supplement, I would kick them off the list of being credible." Gift link…

https://bsky.app/profile/erictopol.bsky.social/post/3loybjaayo22x

Published: May 12, 2025 15:21

When should you take your blood pressure medication? A new randomized trial shows no difference bedtime vs morning @jama.com https://jamanetwork.com/journals/jama/fullarticle/2833860

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Published: May 12, 2025 14:47

New and concerning finding of brain inflammation and cognitive deficit from CAR T cell cancer immunotherapy but ability to mitigate it is also identified (in mouse model) https://www.cell.com/cell/fulltext/S0092-8674(25)00391-5 @cellpress.bsky.social…

https://bsky.app/profile/erictopol.bsky.social/post/3loy4vhw3es2r

Published: May 12, 2025 13:58

The mRNA/nanoparticle platform has saved over 20 million lives during Covid, is being used to treat cancer, rare diseases (via genome editing) and autoimmune diseases, no less many other infectious diseases w/o a vaccine. Now it's under siege. A1, NYT gift…

https://bsky.app/profile/erictopol.bsky.social/post/3loy35n2s322x

Published: May 12, 2025 13:27

From the research and writing SUPER AGERS, some of the practical steps I've incorporated (and suggest avoiding) for extending healthspan gift link…