https://bsky.app/profile/erictopol.bsky.social/post/3lolgr2dx2s2t
Published: May 7, 2025 12:50
Our A.I. times ;-)
@bsky.app.profile.erictopol.bsky.social@rss-parrot.net
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physician-scientist, author, editor https://www.scripps.edu/faculty/topol/ https://erictopol.substack.com
Site URL: bsky.app/profile/erictopol.bsky.social
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Posts: 35
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https://bsky.app/profile/erictopol.bsky.social/post/3lolgr2dx2s2t
Published: May 7, 2025 12:50
Our A.I. times ;-)
https://bsky.app/profile/erictopol.bsky.social/post/3lolfibgtjk23
Published: May 7, 2025 12:27
Get ready for the PROTACS, targeting proteins related to cancer and potentially other diseases a new feature @nature.com https://www.nature.com/articles/d41586-025-01350-2
https://bsky.app/profile/erictopol.bsky.social/post/3loleollghs2q
Published: May 7, 2025 12:13
The gut microbiome uniqueness increases with age but is not associated with longevity or changed ("rejuvenated") by caloric restriction @natmicrobiol.nature.com https://www.nature.com/articles/s41564-025-01963-3…
https://bsky.app/profile/erictopol.bsky.social/post/3lolc6mvsic2o
Published: May 7, 2025 11:28
Our means for lowering LDL cholesterol keeps expanding. A new CETP inhibitor adds to the mix of drug options New RCT @nejm.org (And Lp(a) drugs are not far behind) https://www.nejm.org/doi/full/10.1056/NEJMoa2415820
https://bsky.app/profile/erictopol.bsky.social/post/3lok55nadd22i
Published: May 7, 2025 00:26
Important effort in England to enhance precise and accurate medical forecasting— "Foresight" https://www.nature.com/articles/d41586-025-01422-3
https://bsky.app/profile/erictopol.bsky.social/post/3lojk4yyijc2e
Published: May 6, 2025 18:45
Review of SUPER AGERS by @dshaywitz.bsky.social @wsj.com gift link https://www.wsj.com/health/wellness/super-agers-review-living-the-good-life-9a38c55c?st=um4irz&reflink=mobilewebshare_permalink
https://bsky.app/profile/erictopol.bsky.social/post/3lojafrwocc2c
Published: May 6, 2025 15:51
https://www.nytimes.com/2025/05/06/well/live/eric-topol-longevity-tips.html?smid=nytcore-ios-share
https://bsky.app/profile/erictopol.bsky.social/post/3loj23snd622q
Published: May 6, 2025 13:58
2 podcasts out today on SUPER AGERS and the quest for preventing the 3 major age-related diseases, the Wellderly —with @alanalda.bsky.social clear-vivid-with-alan-alda.simplecast.com —at @healthaffairs.bsky.social …
https://bsky.app/profile/erictopol.bsky.social/post/3loiwqk74vk25
Published: May 6, 2025 12:58
This will surely help American's health status. Not.…
https://bsky.app/profile/erictopol.bsky.social/post/3loipj43ofs23
Published: May 6, 2025 10:49
Today is the birthday for SUPER AGERS, about how we can become one of the "Wellderly," without age-related diseases, like my patient Mrs. Lee Rushall (age 98) https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666
https://bsky.app/profile/erictopol.bsky.social/post/3lohsufms7s2s
Published: May 6, 2025 02:16
A nationwide study in South Korea shows substantial cardiovascular benefit of a Shingles vaccine beyond preventing shingles and the 3 recent natural experiments of some protection vs Alzheimer's disease (open-access)…
https://bsky.app/profile/erictopol.bsky.social/post/3loh6cg7nyc2z
Published: May 5, 2025 20:08
Now the discovery of the 4th gene variant which promotes short sleep (4-6 hours) with full restfulness, potentially a path to a drug for sleep efficiency someday https://www.pnas.org/doi/10.1073/pnas.2500356122
https://bsky.app/profile/erictopol.bsky.social/post/3loeufqg6vc2y
Published: May 4, 2025 22:06
Good summary of this important study linking blood pressure control and reduced dementia https://www.nature.com/articles/s41591-025-03694-8 [contains quote post or other embedded content]
https://bsky.app/profile/erictopol.bsky.social/post/3loenbmae6c2y
Published: May 4, 2025 19:58
My conversation with @melrobbins.bsky.social on extending our healthspan, SUPER AGERS, out in 2 days https://www.melrobbins.com/episode/episode-285/
https://bsky.app/profile/erictopol.bsky.social/post/3loe6rsjn222f
Published: May 4, 2025 15:39
The gylmphatics of our brain, which clear waste products, interact with our immune system and are key to preserving brain health, modulating its aging process, and propensity for neurodegenerative diseases A superb review @cp-immunity.bsky.social…
https://bsky.app/profile/erictopol.bsky.social/post/3loe6afqkkk2t
Published: May 4, 2025 15:29
Common immune system mediated threads of Alzheimer's disease and age-related macular degeneration, a new open-access review @cp-immunity.bsky.social https://www.cell.com/immunity/fulltext/S1074-7613(25)00176-1
https://bsky.app/profile/erictopol.bsky.social/post/3loe4ep4bcc2z
Published: May 4, 2025 14:56
How NOT to make a universal vaccine against any pathogen, no less influenza or SARS-CoV-2 @statnews.com by @helenbranswell.bsky.social https://www.statnews.com/2025/05/03/nih-500-million-univeral-flu-vaccine-project-uses-old-technology/
https://bsky.app/profile/erictopol.bsky.social/post/3loe3hpcwpc2r
Published: May 4, 2025 14:39
Front page @nytimes.com today 1 of 6 charts of the 1st 100 days https://www.nature.com/articles/s41591-025-03694-8
https://bsky.app/profile/erictopol.bsky.social/post/3lobtov4fl22q
Published: May 3, 2025 17:15
What's trusted and verified X4? AG1, the most heavily marketed supplement, with no independent peer reviewed data to show any improvement in health outcomes
https://bsky.app/profile/erictopol.bsky.social/post/3lo7j6jtphs22
Published: May 2, 2025 19:02
Along with prior validation of a heart organ proteomic clock to determine its pace of aging in an individual, there's a heart MRI clock, distinguishing healthy vs unhealthy aging open-access…
https://bsky.app/profile/erictopol.bsky.social/post/3lo7el4vwqs2p
Published: May 2, 2025 17:39
Texas measles update today: 20 more cases since Tuesday, 89 of the 683 cases have been hospitalized US-wide tally likely many thousands across 25+ states, with much under-reporting…
https://bsky.app/profile/erictopol.bsky.social/post/3lo5javcmkk2q
Published: May 1, 2025 23:58
Epigenetic (methylation, biological) age is associated with increased risk of dementia and brain structural changes (including atrophy). From UK Biobank's 280,000 participants, ~4,800 cases of dementia over 14-year follow-up…
https://bsky.app/profile/erictopol.bsky.social/post/3lo4we4psqs2v
Published: May 1, 2025 18:19
After decades of research on stem cells and their reprogramming, we're now seeing extensive clinical trial assessment, some with very encouraging results. This is a new @science.org outstanding review of the biology and ongoing research efforts…
https://bsky.app/profile/erictopol.bsky.social/post/3lo4vc2l3a226
Published: May 1, 2025 18:00
New @science.org An innovative way to deliver drugs to the gut at low doses to suppress inflammation https://www.science.org/doi/10.1126/science.adk7633
https://bsky.app/profile/erictopol.bsky.social/post/3lo2wammtc22x
Published: April 30, 2025 23:12
On the dysregulation of the immune system after infection resulting in #LongCovid, 2 new studies @natimmunol.bsky.social https://www.nature.com/articles/s41590-025-02140-8
https://bsky.app/profile/erictopol.bsky.social/post/3lo2t7ghnms2w
Published: April 30, 2025 22:18
In people with diabetes, a primary concern has been avoiding hyperglycemia, a driver of retinopathy. But hypoglycemia can also be a culprit, as identified here, with a mechanism, in the experimental model…
https://bsky.app/profile/erictopol.bsky.social/post/3lo2sj6fr6s2s
Published: April 30, 2025 22:05
New @nejm.org Another win for semaglutide (Ozempic) and the GLP-1 drugs: reduction of liver fibrosis in MASH https://www.nejm.org/doi/full/10.1056/NEJMoa2413258
https://bsky.app/profile/erictopol.bsky.social/post/3lo2j2ruxhs2l
Published: April 30, 2025 19:16
Cells differ in their cell-division cycle pace. But only now has it been shown that those types with faster cycles are more susceptible to cancer. https://www.nature.com/articles/d41586-025-01138-4
https://bsky.app/profile/erictopol.bsky.social/post/3lo2i575ggs2r
Published: April 30, 2025 19:00
There a lot of use of NAD+ supplements out there, without evidence of anti-aging effects in people. Here's some new data that detracts from NAD's role in modulating the aging process https://www.cell.com/cell-metabolism/fulltext/S1550-4131(25)00212-8
https://bsky.app/profile/erictopol.bsky.social/post/3lo2hy7zovc2b
Published: April 30, 2025 18:57
To restore the gut microbiome after antibiotics, the right diet (rich in carbohydrates, low in fat) was a better approach than fecal microbial transplants (in the experimental model) https://www.nature.com/articles/s41586-025-08937-9…
https://bsky.app/profile/erictopol.bsky.social/post/3lnzvxoajtk2p
Published: April 30, 2025 13:34
That's right. Today's banner headline @nytimes.com
https://bsky.app/profile/erictopol.bsky.social/post/3lnzvcja35c2l
Published: April 30, 2025 13:23
Exercise and brain health: a dose-dependent association with lower amyloid burden https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.70007
https://bsky.app/profile/erictopol.bsky.social/post/3lnzubry6bs2o
Published: April 30, 2025 13:04
"The precision nutrition field is rapidly advancing, drawing considerable attention and investment." A new @naturemedicine.bsky.social review https://www.nature.com/articles/s41591-025-03669-9
https://bsky.app/profile/erictopol.bsky.social/post/3lnzthwwxks23
Published: April 30, 2025 12:50
How not to do a kidney biopsy to diagnose diabetic nephropathy? A.I. of the retina! https://www.thelancet.com/journals/landig/article/PIIS2589-7500(25)00040-8/fulltext
https://bsky.app/profile/erictopol.bsky.social/post/3lnzszabaxc2y
Published: April 30, 2025 12:42
If we really want to take on chronic diseases.... by @virusesimmunity.bsky.social and @hmkyale.bsky.social #LongCovid, post-infection syndromes, immune system assessment and intervention gift link…