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Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.

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Large-scale brain analysis reveals multiple pathways to placebo effects on pain

Published: July 24, 2026 15:20

Scientists have long known that expectations can reduce pain. What remained unclear was whether different ways of generating placebo effects rely on the same biological mechanisms. A new study published in Nature Communications now provides compelling…

Your gut can get jet lag too: How not to waste the first days of your vacation

Published: July 24, 2026 15:00

A dream vacation, an exotic destination, a long-haul flight and finally some well-deserved rest. The problem is that many travelers arrive at their destination only to spend the first days of their vacation struggling with fatigue, sleep disturbances, low…

Redesigned lung cancer drug matches tumor control with fewer off-target interactions

Published: July 24, 2026 14:40

Researchers at Moffitt Cancer Center have developed a new chemical approach that could help make targeted cancer medicines safer and more precise. The discovery gives scientists a new way to design drugs that bind more selectively to cancer-driving…

Inherited gene variants may shape CAR-T therapy benefits and toxic side effects

Published: July 24, 2026 14:00

Chimeric antigen receptor (CAR)-T cell therapy, which reprograms an individual's immune cells to seek out and destroy certain cancer cells, has revolutionized treatment for blood cancers such as lymphoma. But in some patients, the treatment can cause…

Increased social media use linked to anxiety, suicidal ideation among young adults

Published: July 24, 2026 13:40

Teenagers who spent six or more hours a day on social media were twice as likely to experience symptoms of anxiety and three times as likely to report suicidal ideation than those who spent less than one hour on social media each day, according to…

Scientists develop more photostable near-infrared fluorescent dye for longer surgical imaging

Published: July 24, 2026 13:40

Researchers in Korea have developed a new near-infrared (NIR) fluorescent dye with significantly improved photostability, overcoming the rapid signal fading that has long limited fluorescence imaging during surgery for cancer, lymph node mapping and other…

Tiny BAP1 mutations can disrupt internal signals that suppress tumor growth

Published: July 24, 2026 13:20

Scientists at the Institute of Biochemical Sciences at National Taiwan University have uncovered how tiny genetic changes can disable one of the body's most important tumor-suppressing proteins. Their study, published in Nature Communications, reveals how…

Injectable biomaterial harnesses the immune system to promote brain repair after stroke

Published: July 24, 2026 13:00

Biomedical engineers at Duke University have developed an injectable biomaterial that helps transform the cavity left behind after a stroke caused by a blood clot into an environment more supportive of repair. By recruiting the body's own immune cells, the…

Beyond inflammation: Caspase-11's unexpected role in bone remodeling

Published: July 24, 2026 12:40

Millions of people worldwide suffer from osteoporosis, a disease marked by progressive bone loss, weakened skeletal strength and increased fracture risk. Healthy bone is maintained through continuous remodeling, where osteoblasts build new bone and…

New mechanoresistant cancer cells show how they survive high stress environments

Published: July 24, 2026 12:40

When a cancer cell leaves the original tumor to spread to a new, faraway location, it first has to survive what most cells cannot: periodic high-force moments in the vessels and heart of up to 5,000 dynes per centimeter squared as it circulates throughout…

Giving antibodies 'eyes' may help target hidden KRAS mutations in cancer cells

Published: July 24, 2026 12:20

Antibodies are like "guided missiles" that find and attack cancer cells, but cancer-causing mutations inside cells have remained a "blind spot" for treatment because antibodies cannot reach them. KAIST researchers have now succeeded in precisely targeting…

New treatment approach improves survival, reduces recurrence risk in muscle-invasive bladder cancer

Published: July 24, 2026 12:00

Researchers have found that a combination of enfortumab vedotin and pembrolizumab helps patients with muscle-invasive bladder cancer live longer while reducing the risk that their cancer will return after surgery, according to an international phase 3…

Red meat-related gut byproduct tied to higher atrial fibrillation risk

Published: July 24, 2026 12:00

A Cleveland Clinic-led study shows a connection between elevated blood levels of TMAO (trimethylamine N-oxide)—a byproduct of gut bacteria digestion of nutrients found in red meat and other animal products—and a higher risk of atrial fibrillation.

Recall-by-genotype study demonstrates scalable path toward precision psychiatry

Published: July 24, 2026 11:40

Clinical biobanks that combine genomic data with electronic health records (EHRs) have become powerful resources for discovering genetic variants associated with disease. These biobanks may also be used to identify individuals carrying clinically relevant…

Experimental plague vaccine strategy protects mice with missing key immune defenses

Published: July 24, 2026 11:00

The plague has killed more people than World War II. The bacterium Yersinia pestis (Yp), which causes plague, has triggered three major pandemics throughout history, leaving behind a casualty toll of more than 200 million people. Although the plague no…

Birth exposes babies to maternal gut bacteria that help build early microbiomes

Published: July 24, 2026 10:40

The very first thing many babies encounter when they're born is their mother's poop. If they're born vaginally, head down, with the face against their mother's rectum, the pressure can expel fecal material just as they are born. This early exposure is not…

Oral antiviral blocks airborne measles-like virus spread in ferret model

Published: July 24, 2026 10:40

A new oral antiviral drug candidate, administered either before or after direct-contact or airborne exposure to canine distemper virus, which causes measles-like disease in ferrets, blocks virus transmission and reduces clinical symptoms, according to a…

Moral distress: For primary care doctors, 'doing the right thing' can feel impossible

Published: July 24, 2026 10:20

Modern health care systems ask much of primary care doctors. They are expected to diagnose, reassure, coordinate care, manage chronic illness and increasingly fill the gaps when other parts of the system come under strain.

New wearable ring tracks glucose, ketone and other biomarkers in sweat simultaneously

Published: July 24, 2026 10:20

Engineers at the University of California San Diego created a smart ring that simultaneously and continuously monitors up to four different chemical biomarkers from finger sweat. The biomarkers the smart ring can monitor in sweat are glucose, ketones,…

The low‑tech fix that will reduce brain injuries in sport

Published: July 24, 2026 10:00

For parents around the world, weekend mornings often look the same: standing on the sidelines of a soccer field, basketball court or American football field. In Australia's southern states, it's often an Australian rules football oval. But a few weeks ago,…

Could this enzyme help remove 'zombie' cells from our tissues?

Published: July 24, 2026 10:00

Our population is aging. The United Nations reports that by 2050, the number of people age 85 and older on our planet is set to triple. But a longer life span isn't the same as a longer health span (the number of years we spend healthy). Salk Institute…

Is it worse to eat unhealthy food in the morning, or later in the day? And what if you skip breakfast?

Published: July 24, 2026 09:40

Many of us have grown up with the mantra that breakfast is the most important meal of the day. But whether it's snatching an extra half hour of sleep or focusing on getting the kids out of the house, there are various reasons why assembling a healthy…

Clinical trial a step forward in easing kidney dialysis shortfall

Published: July 24, 2026 09:20

A trans-Tasman clinical trial led by University of Queensland researchers has marked a key step toward easing the kidney dialysis crisis in Australia and New Zealand. The researchers led a large-scale trial to test whether a standardized peritoneal…

Clinical trial finds low-dose olanzapine reduces nausea after surgery

Published: July 24, 2026 09:00

Many people feel that the worst part of surgery happens after they wake up. Countless patients who undergo general anesthesia worry about nausea and vomiting, common side effects after surgery. A clinical trial by Yale School of Medicine's Department of…

Scientists find compound that may help muscles stay strong as we age

Published: July 24, 2026 05:00

Skeletal muscle is one of the first tissues to decline with age. This decline can lead to weakness, scarring, fat accumulation inside muscle and the loss of fast-twitch muscle fibers that are important for quick, powerful movements.

Poll: Costs are top health care issue for midterm voters, but fraud tops GOP list

Published: July 23, 2026 23:00

Health care costs top the list of voters' health care priorities for the midterm elections, with half (51%) of all voters and more than half of Democratic (60%) and independent (55%) voters saying the issue is extremely important for candidates to discuss,…

Stroke center anesthesia practices may shape patient outcomes after mechanical thrombectomy

Published: July 23, 2026 21:40

A hospital's overall experience with general anesthesia (GA) or conscious sedation (CS) may influence how anesthesia choice affects patient outcomes during mechanical thrombectomy, according to research presented at the Society of NeuroInterventional…

Novel neurointerventional procedure shows early promise for severe back pain

Published: July 23, 2026 20:00

Researchers at the Society of NeuroInterventional Surgery (SNIS) 23rd Annual Meeting presented an experimental neurointerventional technique designed to treat severe back pain, a leading cause of disability and opioid use, by delivering medication directly…

Molecular imaging enhances diagnosis of fever of unknown origin

Published: July 23, 2026 19:20

PET/CT can add valuable information to aid the diagnosis of fever of unknown origin (FUO), according to a new multicenter, retrospective study published in the June issue of The Journal of Nuclear Medicine. In a cohort of more than 900 FUO patients,…

Persistent money struggles tied to faster brain aging

Published: July 23, 2026 19:10

Persistent financial hardship accelerates age-related cognitive decline, according to a new study led by University College London (UCL) researchers. The study, published in Innovation in Aging, looked at data from 2,759 people in the UK who filled out…

What's the deal with peptides? The hyped market under US review

Published: July 23, 2026 18:40

Glowing skin, deeper sleep, stronger muscles, an alert mind? Such are the enticing promises of peptides, an increasingly buzzy class of substances touted by influencers and celebrities as the key to an optimized life.

Children with severe pneumonia can leave hospital sooner after switching to oral antibiotics, trial shows

Published: July 23, 2026 18:30

Children hospitalized with severe pneumonia can safely switch from injectable to oral antibiotics once they begin to recover, allowing many to return home sooner and complete treatment outside the hospital. That is according to a major international…

Multi-omics map paves way for personalized medicine in Down syndrome

Published: July 23, 2026 18:20

In a recent study published in Nature Communications, researchers from the University of Colorado Anschutz Linda Crnic Institute for Down Syndrome (Crnic Institute) discovered unique biological processes altered among individuals with Down syndrome who…

Natural clotting 'switch' may one day reduce reliance on blood thinners to prevent heart attacks and strokes

Published: July 23, 2026 18:00

Cardiovascular conditions such as strokes or heart attacks are among the most common causes of death in Germany. Today, treatment and prevention are primarily based on so-called platelet aggregation inhibitors and anticoagulants—types of medication…

Misfolded DNA blueprint: A new origin for genetic disease

Published: July 23, 2026 17:40

Congenital heart disease is the most common birth defect, affecting approximately 1 in 100 babies born each year. One of the many causes of this disorder is having only one functional copy of the gene TBX5, rather than the two healthy copies inherited from…

Research reveals persistent racial disparities in stroke treatment and outcomes

Published: July 23, 2026 17:40

Three studies presented at the Society of NeuroInterventional Surgery's (SNIS) 23rd Annual Meeting found that racial, geographic and socioeconomic disparities continue to influence stroke treatment and outcomes across the United States. Together, the…

Blurred genome boundaries emerge as a new layer of Alzheimer's biology

Published: July 23, 2026 17:20

Researchers from Carnegie Mellon University's School of Computer Science, the University of Pittsburgh School of Medicine and the University of Washington have shed new light on Alzheimer's disease that could point to new directions for treatment.

Beyond antibiotics—a paradigm shift toward bacteria-control-centric therapies

Published: July 23, 2026 17:00

Antimicrobial resistance is one of the world's most alarming public health challenges because multidrug-resistant (MDR) gram-negative bacteria increasingly render even last-line antibiotics ineffective, leading to substantially higher mortality rates.…

Overlooked brain protein tied to epilepsy yields first inhibitors in early experiments

Published: July 23, 2026 17:00

Scientists at the Icahn School of Medicine at Mount Sinai have uncovered the first high-resolution structure of NBCn2, a brain protein linked to epilepsy, autism spectrum disorder and other neurological conditions, and developed the first compounds capable…

New PPAR therapies could slow fibrosis in primary biliary cholangitis

Published: July 23, 2026 16:40

Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and…

New strategy could prevent T cell exhaustion and boost immunotherapy

Published: July 23, 2026 16:40

A major pillar of cancer immunotherapy involves stimulating T cells, the specialized killers of the immune system, to attack tumors. But this strategy has been undermined by the tendency of T cells to tire out before finishing the job. When the cells reach…

From urinary tract infection to brain abscess: How bacterial subpopulations can spread to distant body sites

Published: July 23, 2026 16:20

Researchers from the University of Cologne, the German Center for Infection Research (DZIF), and the Broad Institute of Harvard and MIT present a clinical case in the New England Journal of Medicine that provides new insights into the evolution of…

Two ways to read a genome: Body-wide, single-cell atlas maps DNA folding and methylation together

Published: July 23, 2026 16:00

Every cell in the human body carries the same 3 billion letters of DNA, yet a neuron, a heart muscle cell and a pancreatic beta cell each use that shared code to do entirely different jobs. How cells pull off this trick comes down to epigenetics—chemical…

Gene regulation map reveals treatment targets for heart failure

Published: July 23, 2026 15:40

Researchers from the University of California San Diego have created the most detailed map to date of how gene regulation breaks down in human heart failure, revealing how genes are controlled in specific cell types as the disease develops and pointing to…

Cruise ship outbreak highlights need for clear communication on emerging disease threats

Published: July 23, 2026 15:40

A small outbreak of a rare hantavirus on a cruise ship earlier this year captured worldwide attention and sparked concerns about a possible new pandemic. But according to a new University of Maryland School of Medicine (UMSOM) commentary published in JAMA…

Brain immunity may undergo a major midlife overhaul linked to neuroinflammation

Published: July 23, 2026 15:20

A new study indicates that the immune cell landscape of the hippocampus, a brain region critical for learning and memory, rapidly undergoes substantial remodeling beginning in midlife. This previously unrecognized shift suggests a potential mechanism by…

Dormant pigment cells found in vitiligo patches may offer treatment target

Published: July 23, 2026 15:00

Vitiligo is an autoimmune disease in which the body's immune system attacks and destroys melanocytes, the cells that produce the skin pigment melanin. Once the melanocytes are gone, the skin turns white, leading to the characteristic skin patches of the…

Colorectal cancer isn't the only gastrointestinal cancer rising in young adults

Published: July 23, 2026 15:00

You may have heard that colorectal cancer is increasingly affecting young adults. However, it is not the only gastrointestinal (GI) cancer that doctors are diagnosing in patients below the age of 50, explains Christina Wu, M.D., an oncologist at Mayo…

Researchers develop AI-based brain stimulation hologram technology

Published: July 23, 2026 14:40

A research team led by Professor Jae Youn Hwang of DGIST's Department of Electrical Engineering and Computer Science, in collaboration with a team led by Professors Euiheon Chung and Hyuk Sang Kwon of GIST's Department of Biomedical Science and…

Chemotherapy leaves detectable DNA fingerprints in childhood tumors within 18 months

Published: July 23, 2026 14:40

Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids). Researchers say these…

Two new therapies and rapid tests could reshape drug-resistant gonorrhea care

Published: July 23, 2026 14:20

Drug-resistant Neisseria gonorrhoeae (the bacterium that causes gonorrhea) has become one of the most urgent antimicrobial-resistant threats to public health worldwide. Clinicians expect to be confronted by rising rates of treatment failure in the years to…

How systemic immune regulation is 'hijacked' during tumor progression

Published: July 23, 2026 14:00

The immune system plays a critical role in protecting the body from cancer by recognizing and eliminating abnormal cells before they can develop into tumors. This process relies on T cells that can recognize tumor-derived antigens presented by dendritic…

RNA testing uncovers 171 mutations driving MET exon 14 skipping in lung cancer

Published: July 23, 2026 14:00

New research has shown that RNA-based testing can improve the detection and interpretation of clinically actionable genomic alterations that lead to MET exon 14 skipping in patients with lung cancer—important biomarkers that may be missed by DNA-only…

Parents' socioeconomic status is more important than prenatal behaviors to a future child's health, study suggests

Published: July 23, 2026 14:00

Family socioeconomic position may be a more important determinant of children's health than parental behaviors such as smoking, drinking or caffeine consumption, according to a study published in PLOS Medicine by Gemma Sharp from the University of Exeter,…

By the Numbers: This year's Ebola outbreak has spread faster than the worst on record

Published: July 23, 2026 13:50

The Ebola outbreak in Congo has killed over 1,000 people, reaching the grim milestone nearly three times faster than the 2014-2016 Ebola epidemic that is considered the worst on record.

Why air travel can be so hard on the body

Published: July 23, 2026 13:40

At any given time, hundreds of thousands of people are traveling by air. For many, these journeys will pass without consequence. But for some, a routine flight may trigger a health emergency.

Gene activity in blood fluctuates more than expected—and that has consequences for medicine

Published: July 23, 2026 13:40

Take a blood sample from someone in the dead of winter. Take another in midsummer. Same person, same laboratory. And yet, at the level of gene activity, the molecular picture can look surprisingly different. This is not an anomaly. This, a new Nature…

Study reveals stress a significant factor in women experiencing long COVID

Published: July 23, 2026 13:20

Stress appears to play a role in women with young children who are diagnosed with post-acute sequelae of SARS-CoV-2 infection, known as Long COVID, and those who report having Long COVID symptoms. This finding, based on results from 2,500 U.S. women who…

Aspirin reverses diet-driven depression-like behavior in mice

Published: July 23, 2026 13:20

Depression is among the most common psychiatric disorders, estimated to affect between 280 million and 332 million people worldwide. This disorder is characterized by persistent sadness and hopelessness, low energy, a loss of interest in everyday…

Traveling waves in rat brains give hints about information transfer in consciousness

Published: July 23, 2026 13:00

How and why we experience consciousness is a question that has long plagued philosophers and scientists alike. We have come to understand that, when awake, our brains organize neural information for perception, yet we completely lose this organization…

Cerebral small vessel disease: New treatment possibilities for the little‑known condition affecting millions of people

Published: July 23, 2026 12:40

Cerebral small vessel disease (CSVD), which notably increases the risk of stroke and cognitive disorders, is estimated to affect more than 5 million people in France alone. In the absence of a curative treatment, preventing cardiovascular risk factors…

Brain cancer map uncovers thousands of hidden targets for personalized immunotherapies

Published: July 23, 2026 12:40

Researchers from the Clinical Neuroscience Consortium (CNC), a collaborative platform jointly established by the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and Queen Mary Hospital, in collaboration with the Hong Kong Genome Institute…

Adolescent substance use continues to rise through mid-teens, national study finds

Published: July 23, 2026 12:20

As substance use continues to be a major public health concern among adolescents, researchers from the University of California San Diego analyzed the latest data from one of the nation's largest longitudinal studies of youth to better understand when…

Premature blood stem cell aging in sickle cell disease may be reversible

Published: July 23, 2026 12:00

Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital. Patients with sickle cell disease experience higher…

American Indian and Alaska Native adults in California struggle with chronic disease and substance use, study finds

Published: July 23, 2026 11:40

Although American Indian and Alaska Native (AIAN) adults make up 5% of California's adult population, they shoulder a disproportionate burden of chronic disease and substance use, according to a new study from the UCLA Center for Health Policy Research…

A mother's devotion to newborns begins in the brain, study suggests

Published: July 23, 2026 11:40

New research has found that a hormone is responsible for making mothers' interactions with newborns feel rewarding rather than just necessary. The University of Otago—Ōtākou Whakaihu Waka study, published in Science Advances, looked at how a mother's brain…

Ancient molecule made inside tumors drives immune response, study finds

Published: July 23, 2026 11:20

An ancient molecule that existed long before the circulatory system evolved has been found to support cancer immunotherapy. Researchers at Nagoya University in Japan found that complement C3 protein acts inside tumors to prevent the accumulation of…

Modifiable cardiovascular risk factors may drive dangerous plaque buildup in coronary arteries

Published: July 23, 2026 11:00

Cardiovascular risk factors are linked to a higher risk of heart disease, but it has been unknown how they are related to abrupt closure of the coronary arteries leading to heart attack and sudden cardiac death. A study by Mass General Brigham Heart and…

Artery-on-a-chip helps predict stroke risk

Published: July 23, 2026 11:00

Predicting an individual's risk of ischemic stroke is difficult because thrombosis embolization—the process of a blood clot detaching from the area where it formed, traveling and then sticking in another blood vessel—is based on factors unique to each…

How the heart's 'little brain' helps it function and protects it against stress

Published: July 23, 2026 10:28

For years, scientists have known that the heart has its own network of nerves, the intrinsic cardiac nervous system (ICNS), sometimes called its "little brain." Exactly how it functions has remained something of a mystery, but a new paper published in the…

New immune mechanism helps explain why ovarian cancer stops responding to chemotherapy

Published: July 23, 2026 10:20

Scientists at The Wistar Institute have identified a new mechanism behind the chemotherapy resistance that makes ovarian cancer so lethal. In a new study published in The Journal for ImmunoTherapy of Cancer, the researchers show that chemotherapy triggers…

Test offers new way to personalize treatment, reduce unnecessary chemotherapy for patients with breast cancer

Published: July 23, 2026 10:20

A new cancer diagnostic test marketed by Veracyte and developed by a group of researchers, including UNC geneticist Charles Perou, Ph.D., has been found to accurately predict whether patients with breast cancer need chemotherapy or whether hormone therapy…

Could increasing omega-3 intake boost recovery and long-term health in elite athletes?

Published: July 23, 2026 10:00

As the Commonwealth Games approach, athletes chasing every extra edge on the track, court or in the pool might not find it in training, but on their dinner plates. In a study published in Sports Medicine—Open, University of Wollongong (UOW) researchers…

Living in a neighborhood with traffic noise may increase Parkinson's disease risk over time

Published: July 23, 2026 09:30

Loud traffic noise has long been recognized as more than just a disturbance; it is a significant public health concern. Prolonged exposure to excessive traffic sounds can contribute to a range of health problems, including heart disease, hypertension,…

Study finds malaria chemoprevention for school-aged children could deliver billions in health and economic benefits

Published: July 23, 2026 09:20

Providing malaria chemoprevention to school-age children in some of Africa's highest-burden countries could generate billions of dollars in societal benefits while improving health and education outcomes, according to a new study led by researchers at…

Study uses virtual reality to improve walking balance assessment

Published: July 23, 2026 09:00

A new study led by Clarkson University Associate Professor of Physical Therapy Kwadwo Appiah-Kubi introduces a virtual reality tool that could help clinicians better evaluate walking balance and detect balance problems before they lead to falls.

Study reveals how networks of switches in DNA, which regulate gene expression, drive cancer growth

Published: July 23, 2026 07:40

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated. Scientists know these switches play a critical role in cancer and other diseases, but they have yet to fully understand how…

Motor abnormalities predict mental illness in both general and specific symptoms

Published: July 23, 2026 07:00

Motor issues—such as coordination problems, motor slowing or sudden, uncontrolled movements—have been recognized as signs of psychological disorders since the 1800s. How they map to mental health conditions, however, remains unknown.

Drug temporarily reverses autism-like brain changes in adult mice within hours

Published: July 23, 2026 05:00

A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but those brain and behavioral effects may be rapidly, though temporarily, reversible in adulthood with a single dose of the…

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