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🦜 Hypothesis Stream

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The Web. Annotated

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Site URL: hypothes.is/stream

Feed URL: hypothes.is/stream.rss#ToDo/@lma%23ToDo/@lma@mstdn.social%23ToDo/@lma

Posts: 1835

Followers: 1

1.1: Functions and Function Notation

https://hypothes.is/a/_sYa6KGTEfGDp2emNtxH3Q

Published: August 26, 2026 21:20

There is an urban legend that a goldfish has a memory of 3 seconds, but this is just a myth. Goldfish can remember up to 3 months, while the beta fish has a memory of up to 5 months. And while a puppy’s memory span is no longer than 30 seconds, the adult…

Klein & Jones Annotation (#1)

https://hypothes.is/a/G3PWUKGSEfGkofNl_7llqQ

Published: August 26, 2026 21:07

Anchoring what this paper is about This is a subject I am familiar with but it never hurts to review and maybe learn something new.

Impacts of mutation accumulation and order on tumor initiation revealed by engineered murine colorectal cancer organoids

https://hypothes.is/a/kDYcdKGREfGHhjcdQRWS0w

Published: August 26, 2026 21:03

**eLife Assessment** This study presents a valuable finding on impacts of the common driver mutations APC, KRAS G12D, and TP53 in murine colorectal organoids. In particular, the authors examine how the order of APC and TP53 acquisition influences…

Impacts of mutation accumulation and order on tumor initiation revealed by engineered murine colorectal cancer organoids

https://hypothes.is/a/kALtuKGREfGyCg_g7WjRFA

Published: August 26, 2026 21:03

**Reviewer #2 (Public review):** Summary: This study addresses an important and timely question in colorectal cancer biology by systematically examining the effects of the common driver mutations APC, KRAS G12D, and TP53 in murine colorectal…

Impacts of mutation accumulation and order on tumor initiation revealed by engineered murine colorectal cancer organoids

https://hypothes.is/a/j89odqGREfGAa98SEJ3xog

Published: August 26, 2026 21:03

**Author response:** The following is the authors’ response to the original reviews. > **Public Reviews:** > > **Reviewer #1 (Public review):** > > Summary: > > In this study, Li et al. used genetically engineered murine intestinal organoids to…

1.1: Functions and Function Notation

https://hypothes.is/a/jjowVKGREfGlk7MOsf-gPw

Published: August 26, 2026 21:03

We can rewrite it to decide if p is a function of n.A better description of how one would determine whether something is a function based on two variables that appear to be dependent on each other would make sense here. It would seem that they are…

Prenatal Alcohol Exposure Disrupts γ-Secretase Activity and Impairs Learning and Memory in Wild-Type and 3xTg-AD Mice

https://hypothes.is/a/_ToN1qGQEfGdzfd-4hOYGQ

Published: August 26, 2026 20:59

**eLife Assessment** This important study shows that prenatal alcohol exposure produces lasting changes in amyloid precursor protein processing, including altered APP C-terminal fragments and Notch intracellular domain levels, that persist into…

Prenatal Alcohol Exposure Disrupts γ-Secretase Activity and Impairs Learning and Memory in Wild-Type and 3xTg-AD Mice

https://hypothes.is/a/_NZxcqGQEfGfwjuVaB4BSg

Published: August 26, 2026 20:59

**Reviewer #2 (Public review):** Summary: In this study, the impact of prenatal alcohol (PAE) on amyloid precursor protein (APP) C-terminal fragments and notch intracellular domain (NICD) levels in adulthood is measured in 3xTg-AD mice. …

Prenatal Alcohol Exposure Disrupts γ-Secretase Activity and Impairs Learning and Memory in Wild-Type and 3xTg-AD Mice

https://hypothes.is/a/_QiAIqGQEfGFBtMG6ISf8A

Published: August 26, 2026 20:59

**Reviewer #1 (Public review):** Summary: The manuscript by Montenegro and colleagues reports a uniquely significant set of compelling results from a carefully designed study. The findings are fundamental and should substantially advance our…

Prenatal Alcohol Exposure Disrupts γ-Secretase Activity and Impairs Learning and Memory in Wild-Type and 3xTg-AD Mice

https://hypothes.is/a/_KZ_iqGQEfGXJ5eJG7s5gg

Published: August 26, 2026 20:59

**Reviewer #3 (Public review):** Summary: The goal of this study was to test the hypothesis that prenatal alcohol exposure (PAE) can affect Alzheimer's disease (AD) pathogenesis using biochemical proxies, histology, and a behavioral paradigm…

Prenatal Alcohol Exposure Disrupts γ-Secretase Activity and Impairs Learning and Memory in Wild-Type and 3xTg-AD Mice

https://hypothes.is/a/_HModKGQEfGB-tsoQ-vBdw

Published: August 26, 2026 20:59

**Author response:** > **Public Reviews:** > **Reviewer #1 (Public review):** > (1) It would be useful to have a timeline of the study, much like the one provided for the water maze protocol. On that timeline, please include the sample sizes examined,…

"The Allegory of the Cave" by Plato

https://hypothes.is/a/l0_aKKGQEfGWyG9ch_pscg

Published: August 26, 2026 20:56

This entire allegory, Iplato directly explains the symbols: the cave = world of sight; the journey upward = the soul gaining knowledge

1.1: Functions and Function Notation

https://hypothes.is/a/Y6YhxKGPEfGWxF8hwp2fWw

Published: August 26, 2026 20:47

With an input value of a+h, we must use the distributive property.We could include here that f(a) is contained within the output of f(a+h) and substitute it to show that it =f(a)+h^2+2ah+3h

"The Allegory of the Cave" by Plato

https://hypothes.is/a/-eA2CKGOEfG2TIfp-8YEIg

Published: August 26, 2026 20:44

This entire allegoryplato directly explains the symbols: the cave = world of sight: the journey upward = the soul gaining knowledge

What Is Implicit Bias?

https://hypothes.is/a/SzlVeqGKEfGiB2dZSJawPg

Published: August 26, 2026 20:11

I agree with your point that having multiple people involved could help reduce implicit bias. I think having more than one person look at a decision could make it more fair because they might notice things that one person could overlook. I also think it…

"Talk-Talk" — Anike Foundation

https://hypothes.is/a/PZxJXqGKEfGikzfo3_FuIg

Published: August 26, 2026 20:10

the pineapple would ripen and fall towards the road so that it caught the attention of passersby. Although squirrel and her children passed through that road all the time, they stopped stealing Tortoise’s pineapple, not because they did not want to eat…

2.1: Introduction

https://hypothes.is/a/FmthMKGKEfG4YoP9Gptr8Q

Published: August 26, 2026 20:09

Scholars in the field of Ethnic Studies have also maintained a critique of the ways in which other disciplines have been associated with systems of power and domination.Hegemony.

"Talk-Talk" — Anike Foundation

https://hypothes.is/a/BwRO8KGKEfGE4FNWPTE8tg

Published: August 26, 2026 20:09

while she was forgiven, she would continue to be the subject of gossipThe story shows that embarrassment and gossip can be used to discourage people from doing wrong.

SpaceCareerResourceGuide-.pdf

https://hypothes.is/a/9fM2dqGJEfGREyP0hx8M0w

Published: August 26, 2026 20:08

YAGUANG (SUNNY) LUOThe research food technologist is would be a pretty cool career. I didn't even know this was a job. I think the part of going to space would be scary but seeing all the living things up there would be so cool.

"Talk-Talk" — Anike Foundation

https://hypothes.is/a/6KavIKGJEfGWpje6_JjGpg

Published: August 26, 2026 20:08

Tortoise he had forgiven her.I understand why Squirrel is upset because she thought being forgiven meant the situation was over.

When AI Gets It Wrong: Addressing AI Hallucinations and Bias - MIT Sloan Teaching & Learning Technologies

https://hypothes.is/a/wYt-ZqGJEfGDzMvMs1mHaA

Published: August 26, 2026 20:07

I agree with your point on this. AI can be beneficial, but it can also give us misinformation. I also think relying too much on AI can cause a problem because we still need to learn how to think and find information for ourselves. This made me think more…

When AI Gets It Wrong: Addressing AI Hallucinations and Bias - MIT Sloan Teaching & Learning Technologies

https://hypothes.is/a/SgTIDKGJEfGV4JugQkRLGA

Published: August 26, 2026 20:04

Generative AI tools can produce fabricated information that appears authentic—a problem widely known as “hallucination”This surprised me because I thought AI was more advanced than this, and I didn’t think it could or would make up information while making…

"Talk-Talk" — Anike Foundation

https://hypothes.is/a/B2Mk5KGJEfGV34dxhLlqlw

Published: August 26, 2026 20:02

Tortoise would gather his friends and tell them what Squirrel and her children did to him.Is this really forgiveness if Tortoise is still telling everyone about what she did?

When AI Gets It Wrong: Addressing AI Hallucinations and Bias - MIT Sloan Teaching & Learning Technologies

https://hypothes.is/a/2r_fLKGIEfGwQsd4uWd-CQ

Published: August 26, 2026 20:00

These technology tools can generate content that’s skewed or misleadingThis was something that stood out to me because I did not know that AI could create information that is biased or misleading. I think that this is important to know because it shows us…

What Is Implicit Bias?

https://hypothes.is/a/SbL8JqGIEfGYnFtL-71CuQ

Published: August 26, 2026 19:56

It happens to everyone all of the time.This is what surprised me the most in this article because I did not know that implicit bias was something that happens to everyone. I used to think that bias was something that only certain people had, but now I know…

This is Water by David Foster Wallace (Full Transcript and Audio)

https://hypothes.is/a/Orcr3qGIEfGZBWuUWzJASQ

Published: August 26, 2026 19:56

Worship power, you will end up feeling weak and afraid, and you will need ever more power over others to numb you to your own fear. Worship your intellect, being seen as smart, you will end up feeling stupid, a fraud, always on the verge of being found…

"Talk-Talk" — Anike Foundation

https://hypothes.is/a/MJL4fKGIEfGkbBOj0JoUEA

Published: August 26, 2026 19:56

Squirrel heard the news, she pleaded with Tortoise.Squirrel realizes she went too far and is asking for another chance.

This is Water by David Foster Wallace (Full Transcript and Audio)

https://hypothes.is/a/I1rsAKGIEfGfB99z-7DvdA

Published: August 26, 2026 19:55

If you’re automatically sure that you know what reality is, and you are operating on your default setting, then you, like me, probably won’t consider possibilities that aren’t annoying and miserable. But if you really learn how to pay attention, then you…

"Talk-Talk" — Anike Foundation

https://hypothes.is/a/GASKUKGIEfGz9yNSM_QLMQ

Published: August 26, 2026 19:55

Tortoise knew that he had to stop Squirrel from eating his pineapples. He concluded that he would ask the local priest to curse anyone eating his pineapple.Tortoise is trying to find another way to stop Squirrel since he can't fight her.

"Talk-Talk" — Anike Foundation

https://hypothes.is/a/9IbTdqGHEfGW9ONjiV4JeA

Published: August 26, 2026 19:54

whenever Tortoise saw Squirrel on his farm, she was always on top of a palm tree, or some other tree that was impossible for Tortoise to climb.Squirrel has an advantage because Tortoise can't reach her.

What Is Implicit Bias?

https://hypothes.is/a/65kCeqGHEfGUmGf3ngocPA

Published: August 26, 2026 19:54

Research strongly suggests, however, that your decision might still be influenced by the race and gender of the applicant.This stood out to me because it shows that people can be influenced by things without even realizing that they are affecting their…

This is Water by David Foster Wallace (Full Transcript and Audio)

https://hypothes.is/a/42cDmqGHEfGkaiNKGk1T5g

Published: August 26, 2026 19:54

But most days, if you’re aware enough to give yourself a choice, you can choose to look differently at this fat, dead-eyed, over-made-up lady who just screamed at her kid in the checkout line. Maybe she’s not usually like this. Maybe she’s been up three…

The Despising King — Anike Foundation

https://hypothes.is/a/if8NVKGAEfGVDtvqYEG33Q

Published: August 26, 2026 19:01

One day, the Council of Chiefs decided to crown himWhy would the chiefs crown him if they knew he was not going to listen to anyone?

The Despising King — Anike Foundation

https://hypothes.is/a/_OPekKF_EfGHhWd7pr3klg

Published: August 26, 2026 18:57

He did what was right in his own eyes and not what would benefit the people.This started to makes me think he was becoming selfish. A good king should think about his people, not just himself.

The Despising King — Anike Foundation

https://hypothes.is/a/ycut2qF_EfGImfNhZ1yXKw

Published: August 26, 2026 18:56

The heir apparent began to rule, but he did not take any advice from the Council of Chiefs.This is a major change from his father. He refuses to listen to people who are trying to help him.

The Despising King — Anike Foundation

https://hypothes.is/a/cXIC9qF_EfG1_5u0A3tTcw

Published: August 26, 2026 18:53

He could not perform the ritualThis decision caused serious consequences for his father and his future as king.

The Despising King — Anike Foundation

https://hypothes.is/a/QWB1UqF_EfGoUlM4UhdFPg

Published: August 26, 2026 18:52

The young man agreed, but before sunset, he went to his concubine’s houseI think this was irresponsible because he knew his father needed him.

Facilitative Teaching for Transformational Learning in the Age of AI

https://hypothes.is/a/weSdHKF-EfGZ-88ctQgcEQ

Published: August 26, 2026 18:48

the AI-augmented workforce that increasingly needs "super facilitators"—professionals skilled at fostering collaborative, problem-solving conversations.FootnoteThe "new" workforce profile?

The Despising King — Anike Foundation

https://hypothes.is/a/i7Fs_KF-EfGkIVu4dnAsDQ

Published: August 26, 2026 18:47

The King would seek advice in every matterThe King understands that listening to other people helps him rule well.

The Despising King — Anike Foundation

https://hypothes.is/a/ZdccXKF-EfGWeu-UibzxLQ

Published: August 26, 2026 18:46

The King had a kind heart and his people loved him.The King seems like a good ruler because his people respect and love him.

W1.1.Introducing East Asia.pdf

https://hypothes.is/a/vvM0hKF9EfG909_WnzpjMw

Published: August 26, 2026 18:41

East Asia is very diverse and has a multitude of backgrounds, advancements, and philosophies without history. To group all these different countries under one category of "East Asia" is acceptable because all fall under the geographical topic, but there…

Yacob and Amo: Africa’s precursors to Locke, Hume and Kant – Dag Herbjørnsrud | Aeon Essays

https://hypothes.is/a/RCymVKF9EfGBDDPuB4cQ9A

Published: August 26, 2026 18:38

In his Hatäta, Yacob criticises his contemporaries for not thinking independently, but rather accepting the claims of astrologers and soothsayers just because their predecessors did soHow commonplace was literacy for philosophical texts in this time period…

Yacob and Amo: Africa’s precursors to Locke, Hume and Kant – Dag Herbjørnsrud | Aeon Essays

https://hypothes.is/a/GvLb8KF9EfGy-1vmeMIMZA

Published: August 26, 2026 18:36

Yacob, who was teaching in the Axum region, had declared that no religion was more right than any other, and his enemies brought charges against him to the king.I found it very interesting that this foundational idea of religious freedom and rejection of…

The Best Cook With a Sore and the Wise King — Anike Foundation

https://hypothes.is/a/3zrRYqF8EfGX8DejbyYYug

Published: August 26, 2026 18:35

On the day of the event, the Cook prepared food for the Duke and his guests. They all ate and were happy.Mamara is finally being recognized for her talent instead of her appearance.

The Best Cook With a Sore and the Wise King — Anike Foundation

https://hypothes.is/a/xdku-KF8EfGP0VOd3bKkyA

Published: August 26, 2026 18:34

The king pleaded with the people not to tell anybody who had not known that the Cook had a sore, and they obeyed.I think this shows respect for Mamara and protects her from being embarrassed.

The Best Cook With a Sore and the Wise King — Anike Foundation

https://hypothes.is/a/gkf7pqF8EfGzuHcvXRYFWA

Published: August 26, 2026 18:32

The Duke in his wisdom decided to employ a doctor to treat the cook.The Duke shows kindness by helping her instead of judging her.

The Best Cook With a Sore and the Wise King — Anike Foundation

https://hypothes.is/a/XjDkHKF8EfGBRvtLLlo97A

Published: August 26, 2026 18:31

After the contest, Mamara was judged to be the best and the winner.This proves that the people who judged her because of her sore were wrong.

The Best Cook With a Sore and the Wise King — Anike Foundation

https://hypothes.is/a/FBSSNKF8EfGHcuPT22nd4w

Published: August 26, 2026 18:29

The chief who recommend Mamara advised the Duke to conduct a contest for the cooks so that he could choose the best of them.I think Mamara will use the contest to prove everyone wrong.

The Best Cook With a Sore and the Wise King — Anike Foundation

https://hypothes.is/a/sKUAxqF7EfG4Ik9pN8unkw

Published: August 26, 2026 18:26

Although they knew that Mamara was the best in her community and all the neighboring villages, they did not contact her because of the ugly sore at the back of her hand.I think this is unfair because they are judging her before seeing what she can do.

The Best Cook With a Sore and the Wise King — Anike Foundation

https://hypothes.is/a/juHsVqF7EfGZR5vOjIEZfw

Published: August 26, 2026 18:25

He needed a cook to prepare food for his guests.This gives Mamara a chance to show her cooking ability.

The Best Cook With a Sore and the Wise King — Anike Foundation

https://hypothes.is/a/eXIvUqF7EfGrgHvYgH8zlw

Published: August 26, 2026 18:25

but she had an ugly sore at the back of her left hand that refused to heal.I think this sore is going to cause problems for Mamara even though it doesn't affect her cooking.

The Best Cook With a Sore and the Wise King — Anike Foundation

https://hypothes.is/a/Y4V59qF7EfG88IsHZ_hyOw

Published: August 26, 2026 18:24

Mamara was a very beautiful lady and a good cookMamara is talented, but the story is going to show that people focus on something else about her.

Week-6_2_9_Newkirk_The-First-Five-Minutes_Conferences.pdf

https://hypothes.is/a/ueLQXKF0EfGLYeu9zc54Kw

Published: August 26, 2026 17:36

What stands out in this conference is the domination of the teacher.She speaks more than twice as much as the student (351 to 162 words),but a word count alone does not make clear the nature of thatdominationAfter reading the conversation between the…

1584 - Abasing Spain - US History 1 with Primary Source Anthology - Obsidian Publish

https://hypothes.is/a/38SU3KFzEfGD_c8hjUX4kQ

Published: August 26, 2026 17:30

If these enter into the due consideration of wise men and if platforms of these things be set down and executed duly and with speed and effect, no doubt but the Spanish Empire falls to the groundThis is how they think they can defeat Spain.

1.8: Glossary

https://hypothes.is/a/kuE-fKFzEfG2eI-p4GpdNQ

Published: August 26, 2026 17:28

1. What are the personal, professional and public benefits of enhancing your public speaking skills?Enhancing your public speaking skills allows for benefits in personal, professional, and public scenarios because it equips the communicator with the skills…

Week-6_2_9_Newkirk_The-First-Five-Minutes_Conferences.pdf

https://hypothes.is/a/gF6PjqFzEfGvVLsysApuIA

Published: August 26, 2026 17:28

Was there a part thatyou thought needed work still? You know, something you were sort ofunhappy with?I appreciate how the teacher is being very transparent with the student and constantly asking for their opinion with these open ended questions.

1568 - An English Free-booter - US History 1 with Primary Source Anthology - Obsidian Publish

https://hypothes.is/a/eFU6GKFzEfG3MSchvtkoHA

Published: August 26, 2026 17:27

I found also in the same port 12 ships which had in them by the report 200,000 lb. in gold and silverThis probably changed Europe for a while.

(2) Vintage Typewriter Enthusiasts | It's one problem after another. | Facebook

https://hypothes.is/a/NCXoVqFzEfGm9OOcEXQqiQ

Published: August 26, 2026 17:25

I worked in the SCM plant in Groton NY back in the 60's. This is one of the machines that we built there. Plastic was never ment to last over 50 years.via Greg Hubert

(2) Vintage Typewriter Enthusiasts | It's one problem after another. | Facebook

https://hypothes.is/a/409jlKFyEfGxk3_OnLc4KA

Published: August 26, 2026 17:23

I would be more than happy to help you fix it, or if you are just done with it, I have a large number of machines for sale. I have everything from the 1920's to the 1980s, Manual, electric, electronic. I have portables and ultra portables. I also sell mine…

Week-6_2_9_Newkirk_The-First-Five-Minutes_Conferences.pdf

https://hypothes.is/a/0lyIgqFyEfGHcZPdXh8gGA

Published: August 26, 2026 17:23

The agenda often deals with a possiblerevision of the paper, but there are other possibilities: it could dealwith the writing process of the student or with a paper that is yet tobe written.This paragraph mainly sets up the importance of an agenda during…

1542 - De Soto on the Mississippi - US History 1 with Primary Source Anthology - Obsidian Publish

https://hypothes.is/a/x4lpcKFyEfG-d2uImtBGRQ

Published: August 26, 2026 17:22

Many of these animals escaped and went feral in America.This might have been the start of wild pigs in America.

1497 - First English Voyage - US History 1 with Primary Source Anthology - Obsidian Publish

https://hypothes.is/a/kJoLpKFyEfGddTeNMxKdUw

Published: August 26, 2026 17:21

He further says that he was once at Mecca, whither the spices are brought by caravans from distant countries. And having inquired from whence they were brought and where they grow, they answered they did not knowMultiple countries are selling spices, but…

Week-6_2_9_Newkirk_The-First-Five-Minutes_Conferences.pdf

https://hypothes.is/a/SsoknKFyEfGqF--6jzEUcw

Published: August 26, 2026 17:19

There is no neat way to reconcile these mandates, no formulato prevent missteps just the endless prospect of gambling, of riskingsilence at some points and assertiveness at others.Similar to the talks we had in training, there is not exactly a correctly…

(1) Vintage Typewriter Enthusiasts | Facebook

https://hypothes.is/a/NwB47qFyEfGLUJOvZh9gsw

Published: August 26, 2026 17:18

gray fivesTypewriter repair people colloquially called the Underwood Touchmaster 5 the "gray fives". via Jim Tuxbury on Facebook

(1) Vintage Typewriter Enthusiasts | Facebook

https://hypothes.is/a/7FHJOKFxEfGIutOE2HN_IA

Published: August 26, 2026 17:16

I am an old typewriter repairman. I worked at the underwood assembly plant in Hartford Connecticut for two years and became a typewriter service man for 20 years in St. Louis. I don’t own any typewriter’s I know the gray fives like the back of my hand. As…

1492 - Columbus' Discovery - US History 1 with Primary Source Anthology - Obsidian Publish

https://hypothes.is/a/sTKLCKFxEfGItmPUjhdXOw

Published: August 26, 2026 17:15

They afterwards came to the boats of the vessels swimming, bringing us parrots, cotton thread in balls, and spears, and many other things which they bartered for others we gave themThey were showing peace by exchanging gifts.

Trans-acting mutations reveal non-nuclear modulators of both intrinsic and extrinsic gene expression noise in a eukaryote.

https://hypothes.is/a/hUfAbKFxEfGItRugi2IUyQ

Published: August 26, 2026 17:13

**Note:** This preprint has been reviewed by subject experts for *Review Commons*. Content has not been altered except for formatting. Learn more at [Review Commons](https://reviewcommons.org) ----- ### Referee \#2 #### Evidence, reproducibility and…

Trans-acting mutations reveal non-nuclear modulators of both intrinsic and extrinsic gene expression noise in a eukaryote.

https://hypothes.is/a/hRoRiqFxEfG3Jm9-JEGJHA

Published: August 26, 2026 17:13

**Note:** This preprint has been reviewed by subject experts for *Review Commons*. Content has not been altered except for formatting. Learn more at [Review Commons](https://reviewcommons.org) ----- ### Referee \#1 #### Evidence, reproducibility and…

Trans-acting mutations reveal non-nuclear modulators of both intrinsic and extrinsic gene expression noise in a eukaryote.

https://hypothes.is/a/hXsA0KFxEfGIVrdG4yM1MQ

Published: August 26, 2026 17:13

**Note:** This response was posted by the corresponding author to *Review Commons*. The content has not been altered except for formatting. Learn more at [Review Commons](https://reviewcommons.org) ----- ### Reply to the reviewers We provide below a…

Lynx: Unlock Native for More

https://hypothes.is/a/b3LGVqFxEfGuPEPbww5SeA

Published: August 26, 2026 17:13

but we believe in opening source what we actually rely on. In fact, we are moving all development to GitHub, making it open and transparent to the community.

2.1: Perception Process

https://hypothes.is/a/nVwKBKFoEfGvLwdWNRMSQw

Published: August 26, 2026 16:10

We tend to pay attention to information that we perceive to meet our needs or interests in some way. This type of selective attention can help us meet instrumental needs and get things done. When you need to speak with a financial aid officer about your…

A functional influence based circuit motif that constrains the set of plausible algorithms of cortical function

https://hypothes.is/a/IJUW3KFoEfGGgaOgTfqx0w

Published: August 26, 2026 16:06

**eLife Assessment** This fundamental work significantly advances our understanding of the circuit-level implementation of predictive processing by elucidating the functional influence between putative prediction error neurons in layer 2/3 and…

A functional influence based circuit motif that constrains the set of plausible algorithms of cortical function

https://hypothes.is/a/IC_1XqFoEfGA-C9N6CuP3g

Published: August 26, 2026 16:06

**Reviewer #2 (Public review):** This manuscript reveals functional connectivity of two different classed of cortical neurons that respond in opposite ways to mismatches between sensory and top-down inputs. These data are very valuable because…

A functional influence based circuit motif that constrains the set of plausible algorithms of cortical function

https://hypothes.is/a/IGMl-qFoEfGtPYu9rAXfPw

Published: August 26, 2026 16:06

**Reviewer #1 (Public review):** Vasilevskaya and Keller test different models of cortical function through the lens of predictive processing, a powerful framework for the brain to learn and predict the statistics of the world via generative internal…

A functional influence based circuit motif that constrains the set of plausible algorithms of cortical function

https://hypothes.is/a/H_4spKFoEfGGgI9_Yn9OWQ

Published: August 26, 2026 16:06

**Reviewer #3 (Public review):** Vasilevskaya and Keller set out to experimentally distinguish between two variants of predictive processing: a hierarchical and a non-hierarchical variant. The hierarchical variant assumes a hierarchical organization…

A functional influence based circuit motif that constrains the set of plausible algorithms of cortical function

https://hypothes.is/a/H8jWbKFoEfGQizOXHDZBzQ

Published: August 26, 2026 16:06

**Author response:** The following is the authors’ response to the original reviews. We thank you for the time you took to review our work and for your feedback! We have performed the following additional analyses: (1) We analyzed the optomotor mismatch…

Unidades Semánticas

https://hypothes.is/a/34PheKFnEfGMjKeClj4NfA

Published: August 26, 2026 16:04

Completamente de acuerdo contigo. He estado tan acostumbrado a softwares de escritura como Word, que a veces complejizo lenguajes como Markdown que, con la práctica, es mucho más sencillo y asertivo de utilizar.

Applying the Baldwin Test to Ed-Tech — Civics of Technology

https://hypothes.is/a/y1hC6KFnEfG2_Je8pGQc6A

Published: August 26, 2026 16:04

2) Identify any obstacles to our own understanding of a technology that result from failures of corporate or government transparency.This is one of the most important commitments because it ensures that we are able to identify any foul play on our personal…

2.1: Perception Process

https://hypothes.is/a/q-2y-KFnEfGBqStBe9oCHw

Published: August 26, 2026 16:03

It’s probably better to have a serious conversation with a significant other in a quiet place rather than a crowded food court. As we will learn later in the chapter titled “Public Speaking in Various Contexts”, altering the rate, volume, and pitch of your…

Unidades Semánticas

https://hypothes.is/a/n7TYNqFnEfGcZo_D7qDoeQ

Published: August 26, 2026 16:03

Desarrollar una actitud crítica respecto a la selección de software y hardware adecuadoEste punto de los RAE es uno de los que más me gusta abordar en la clase porque en otras asignaturas usualmente se alienta el uso de la IA y otras herramientas, a veces…

9781439064184.pdf

https://hypothes.is/a/9RVR0KFmEfG7i6_WvKeRxA

Published: August 26, 2026 15:58

G is a group under this operationNote that this definition does not include closure, so a group under this operation is not necessarily a group (see example 5).

Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

https://hypothes.is/a/PwT1TqFmEfGY4TeqxbK8ew

Published: August 26, 2026 15:53

**eLife Assessment** This important study provides new insights into the patterns of organelle inheritance in the protozoan parasite Toxoplasma gondii. The authors introduce an innovative dual-labeling approach to distinguish maternally inherited from…

Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

https://hypothes.is/a/Pp7cZKFmEfGIES_tFNfyHQ

Published: August 26, 2026 15:53

**Reviewer #2 (Public review):** Summary: Toxoplasma gondii is an obligate intracellular parasite and the causative agent of toxoplasmosis. Parasite invasion of host cells, intracellular replication, and subsequent egress, which results in…

Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

https://hypothes.is/a/PtIdrqFmEfGXH-fsYt8V6Q

Published: August 26, 2026 15:53

**Reviewer #1 (Public review):** Summary: This work asks the question of how different organelles and structures in the apicomplexan parasite Toxoplasma gondii are recycled and/or segregated to the daughter cells during cell replication. In…

Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

https://hypothes.is/a/PmfCaqFmEfGNzI_Y318lCw

Published: August 26, 2026 15:53

**Reviewer #3 (Public review):** Summary: Knoerzer-Suckow et al. explore the mechanisms of organelle inheritance during endodyogeny in Toxoplasma gondii using an innovative dual-labeling approach to track the distribution of maternal organelles…

Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

https://hypothes.is/a/PheiMKFmEfGmuONMWrxC2w

Published: August 26, 2026 15:53

**Author response:** The following is the authors’ response to the original reviews. We sincerely thank the reviewers and the Reviewing Editor for their careful evaluation of our manuscript and for their constructive and insightful comments. Their…

2.1: Perception Process

https://hypothes.is/a/A8Tm4qFmEfGZlDMiKPjj9w

Published: August 26, 2026 15:51

It is probably not surprising to learn that visually and/or aurally stimulating things become salient in our perceptual field and get our attention. Creatures ranging from fish to hummingbirds are attracted to things like silver spinners on fishing poles…

Unidades Semánticas

https://hypothes.is/a/iYO8rKFjEfGeW6ePaUOyrQ

Published: August 26, 2026 15:33

sistemas expertosSegún la Wikipedia, > Un [sistema experto](https://es.wikipedia.org/wiki/Sistema_experto) (SE) es un sistema informático que emula el razonamiento actuando tal y como lo haría un experto en cualquier área de conocimiento.

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