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Site URL: hypothes.is/stream

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17.2: Before Reading

https://hypothes.is/a/Y0hr3JwEEfGUuBPUP2PQ9g

Published: August 19, 2026 19:30

One step you can take involves inquiry: asking yourself questions that will help to focus your reading experience.Ask yourself these questions before you write. Important!

AEC295_AnimComms-Course_Guide-v3.1_2026.08.17

https://hypothes.is/a/Gx1D0pwEEfGyeDc3s0PJSw

Published: August 19, 2026 19:28

Students are expected to complete exams and quizzes individually, using onlythe materials explicitly permitted by the instructor. Students may study, complete readings, and take notesin collaboration, but each student is expected to complete their own aids…

AEC295_AnimComms-Course_Guide-v3.1_2026.08.17

https://hypothes.is/a/wqF4VJwDEfG8d8-Y73iB_g

Published: August 19, 2026 19:25

I will carefully consider all polite, professionally argued, and well-reasoned disputations of your scorefor any assignment. Any disputation must be made prior to the date of the subsequent assignment;You are able to politely refute your grade if you…

17.1: Becoming a Critical Reader

https://hypothes.is/a/qxhETJwDEfGH4V98pPfESg

Published: August 19, 2026 19:24

No text, however well written and authoritative, contains its own, pre-determined meaning.Stands out to me, and good to know!

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/dbKxjpwDEfG5wE9B-0Av5w

Published: August 19, 2026 19:23

When you reach the little house, the place your journey started, you will recognize it, although it will seem much smaller than you rememberthis instruction means the way you went or the process you have been working on and if you go over them again it…

5-Minute Personality Test (Document)

https://hypothes.is/a/cv3RTpwDEfG3_LsnNeDpPQ

Published: August 19, 2026 19:23

I got the golden retriever and Jack Russell Terrier. The only thing I don't agree with is that I am not over-accommodating at all because I get annoyed too quickly.

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/Z-axSpwDEfGgNJsQ12QEzw

Published: August 19, 2026 19:23

OrThe beggining is the end and the end the begining is oddly satisfying its as if you've completed your journey and you will rest before you begin again

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/CZs4uJwDEfG7pP8hnCeuvw

Published: August 19, 2026 19:20

When you come back, return the way you came. Favors will be returned, debts will be repaid.I think that this poem is trying to teach people that if you are kind to other things they will be kind in return

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/6zkxGJwCEfGXPGey2WNscQ

Published: August 19, 2026 19:19

However, if any creature tells you that it hungers, feed it. If it tells you that it is dirty, clean it. If it cries to you that it hurts, if you can, ease its pain.I think this is trying to say be selveless and help people in more need of thing then…

17.1: Becoming a Critical Reader

https://hypothes.is/a/zc03RpwCEfG0Xuf1Yoxdcg

Published: August 19, 2026 19:18

Critical readers interact with the texts they read through carefully listening, writing, conversation, and questioning.Important! Write this down.

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/w-T9IpwCEfGs2TfKIgcPSw

Published: August 19, 2026 19:18

If an eagle gives you a feather, keep it safe.If someone gift you something vauable or precious, you should protect it and keep it safe because it was an important gift.

6.3: Contested and Competing Meanings in Chicanx and Latinx Studies

https://hypothes.is/a/lUlQxpwCEfGmlN8uUjw93A

Published: August 19, 2026 19:17

Chicanx feminism has always created space in the community and in higher education, but it has simultaneously always faced individual or group suppression to Chicanx machismo. Many male Chicano activists expressed that they felt Chicana feminist groups…

Chapitre 13 — Donner une institution au non-événement – La société au prix du risque

https://hypothes.is/a/kTjpfpwCEfGfHzdEwJ337w

Published: August 19, 2026 19:17

Elle avait aussi révélé un défaut de la relation annuelle.C'est une vraie question. Qu'est-ce que la résiliation à tout moment au bout d'un an a réellement apporté à l'assurance, au bout du compte ?

Chapitre 13 — Donner une institution au non-événement – La société au prix du risque

https://hypothes.is/a/RNa6jpwCEfGwAkOPCH5AlQ

Published: August 19, 2026 19:14

Le projet pilote fut accepté.Vous pouvez m'assurer que cela a vraiment existé? Dites-moi, allons, ne me racontez plus d'histoires :o)

Classroom Norms & Procedures

https://hypothes.is/a/EkA_oJwCEfGOK7vbwyNhpg

Published: August 19, 2026 19:13

If students do not understand the reason behind the consequence or do not care about the impact of the consequence, then the chances of the consequence changing behavior decrease.How can we as teachers get students to understand or care about the…

1.2: Our Narratives

https://hypothes.is/a/DTC2vJwBEfGUrdufQwSxew

Published: August 19, 2026 19:06

I had nieces and nephews that were taken away by the state and placed in foster care when they should have been placed by law with my mom and our family.This statement shows that strong emotional situations can inspire some individuals to help and prevent…

Chapitre 10 — Quand le climat entre dans les contrats – La société au prix du risque

https://hypothes.is/a/qwZcVpvuEfGk-s8pCZLl9g

Published: August 19, 2026 16:54

La carte retient un phénomène, une période, une résolution, un scénario et un seuil. Elle peut être exacte dans ce qu’elle représente et silencieuse sur l’endettement, le statut des locataires, le coût des travaux, la disponibilité des artisans ou les…

What Employers Need: Meaningful Framework for Work-integrated Learning | wilaccelerator

https://hypothes.is/a/Vg4GQJvuEfGkHMNUcpiAfQ

Published: August 19, 2026 16:52

Reporting should be automatic, not something employers need to request. Rather than the onus being put on the employer to request access, they should be encouraged to participate in facilitated meetings and introductions.Simple systems thinking and change…

What Employers Need: Meaningful Framework for Work-integrated Learning | wilaccelerator

https://hypothes.is/a/AV_rGJvuEfGa9B_1eMrYyg

Published: August 19, 2026 16:49

Small organizations oftentimes will not have the staff or resources to dedicate toward [work-integrated learning projects] so the need to have a plug and play processes is imperative to successful partnerships at this scale.”Partnership is not just…

Naše služby | Sociální sítě v bezpečí

https://hypothes.is/a/-AO4sJvtEfGfKrM_4NIiAw

Published: August 19, 2026 16:49

Od prevence přes obnovu až po dlouhodobé zabezpečení. Pomáháme jednotlivcům, firmám i celebritám chránit jejich digitální majetek.Nechybí tady v té větě čárky? Od prevence přes obnovu až po dlouhodobé zabezpečení. Pomáháme jednotlivcům, firmám i celebritám…

Vzdálená pomoc - stáhněte RustDesk | Sociální sítě v bezpečí

https://hypothes.is/a/c0WyVJvtEfGUkE95MlCSmA

Published: August 19, 2026 16:45

Vzdálené připojení je bezpečné - a vy ho máte vždy pod kontrolouSmazat pomlčku u Vzdálené připojení je bezpečné - a vy ho máte vždy pod kontrolou.

Classroom Norms & Procedures

https://hypothes.is/a/Yb66EpvtEfGNR09HxCI0aw

Published: August 19, 2026 16:45

The more you plan and define your expectations, the more likely your classroom will run smoothly. Having a plan does not mean you won’t have to make adjustments along the way, but with a system in place, you and your students can spend more time focusing…

Chapitre 10 — Quand le climat entre dans les contrats – La société au prix du risque

https://hypothes.is/a/SHlAaJvtEfGU9Ns9g3AGpA

Published: August 19, 2026 16:44

Un tarifJe dirai une évolution de tarif plutôt qu'un tarif, c'est uniquement dans ce cadre que l'assuré est captif ?

Classroom Norms & Procedures

https://hypothes.is/a/voH-GJvsEfGYxGfF3DW7sw

Published: August 19, 2026 16:40

Consequences are the result of an action. Therefore, consequences could result in a positive or negative outcome. Applying positive consequences can be used to reinforce desired behavior and help you establish a positive learning environment. However,…

Classroom Norms & Procedures

https://hypothes.is/a/yngV0pvrEfGrcJ9-8U5oMw

Published: August 19, 2026 16:34

Consider how the typical set of classroom rules listed below defines expectations for student behavior. Treat others with courtesy and politeness. Make sure to bring the required materials to class and to activities. Be on time for class and other…

A sequence-to-function model to predict T7 transcription rates and redesign T7 expression systems with lowered production of immunogenic RNA byproducts

https://hypothes.is/a/4DMTzpvpEfGgHf-gOokFnA

Published: August 19, 2026 16:20

a sequence-to-function machine learning model that predicts the T7 transcription rate on arbitrary DNA sequence across a 500-fold range with high accuracy (R2 = 0.80)Would be interesting to know how this compares to the mechanistic model in promoter…

Rezervace konzultace | Sociální sítě v bezpečí

https://hypothes.is/a/PacGNJvoEfGQ0ztp7yZFcg

Published: August 19, 2026 16:08

SlužbaÚvodní konzultaceTermín21. 8. 2026 v 14:00Typ termínuvlastní návrh - podléhá schváleníDélka20 minut zdarma, poté dle domluvyVratná záloha2 900 Kč (platí se až po schválení termínu)JménoTomáš SkalkaE-mailtomas.skalka05@seznam.czS čím pomociOsobní…

eXtensible Host Controller Interface for Universal Serial Bus (xHCI)

https://hypothes.is/a/j6QgOpvYEfGERL8PqirQNA

Published: August 19, 2026 14:16

Note that Figure 3-2 does not imply a particular xHC implementation, however the functional partitioning that it illustrates is useful for this discussion. The Host Interface Logic manages the Registers and DMA associated with the…

AEC295_AnimComms-Course_Guide-v3.1_2026.08.17

https://hypothes.is/a/x2Qu0JvXEfG224scuniczQ

Published: August 19, 2026 14:10

At minimum, you will need to complete the readings, complete the assignments, and meetproject deadlinesThis is in addition to studying time for optimal success.

Good Enough and Better Than Me: Two Problematic Student Perspectives on Gen AI

https://hypothes.is/a/sy7dypvXEfGf9VNV0LXQPw

Published: August 19, 2026 14:10

There was a common concern across senior school visual arts students that there would be no point going into career pathways in the creative industries because AI is “already better than them” at producing illustrations and digital artworks.Many students…

eXtensible Host Controller Interface for Universal Serial Bus (xHCI)

https://hypothes.is/a/qXOoBpvXEfGjRlPdw0S7HA

Published: August 19, 2026 14:09

The xHCI architecture allows the USB3 host controller to provide USB functionality for all speed devices without requiring, as in previous generations, companion controllers along with the associated software support for their respective drivers. The…

Good Enough and Better Than Me: Two Problematic Student Perspectives on Gen AI

https://hypothes.is/a/IR8f2pvXEfGWdNvap95BDQ

Published: August 19, 2026 14:06

tasks that they perceived as low stakes, including homework, classwork that wasn’t being directly assessedStudents seem not to care as much about homework as they do classwork and quizzes. The no pressure aspect of it might lead to them believing it might…

AEC295_AnimComms-Course_Guide-v3.1_2026.08.17

https://hypothes.is/a/4C9vKpvWEfGU0Du_uUogDg

Published: August 19, 2026 14:04

Attendance is mandatory for all meetings of this course.Attendance factors into participation grade and can affect class assignments.

https://bafkreigwgp2bucfqaijb55ufmdot7cm4mmqamf3atjwnudpjf4uqwzg22i.ipfs.inbrowser.link/?filename=GMT20260812-140213_Recording.transcript.vtt

https://hypothes.is/a/Nj7AApvVEfGcFycIERH7mg

Published: August 19, 2026 13:52

Make it as We Use IT

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/Lg6dWJvVEfGstiseVYEfDg

Published: August 19, 2026 13:52

If you turn around here, you can walk back, safely; you will lose no face. I will think no less of you.in this segment, the author tells us that if we desire, we can go back to how our life was originally, although it is likely that the compulsion of…

https://bafkreigwgp2bucfqaijb55ufmdot7cm4mmqamf3atjwnudpjf4uqwzg22i.ipfs.inbrowser.link/?filename=GMT20260812-140213_Recording.transcript.vtt

https://hypothes.is/a/Jb3VGpvVEfGMO_-XMrkEUw

Published: August 19, 2026 13:51

The exploratory experimental workflow for working with video and transcript for a call using/composing existing minimal workable capabilities of IndyWiki and IPFS+CryptPad InterPlayN

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/SrQufpvUEfGlBSNmVKYbow

Published: August 19, 2026 13:45

They may do favors for you, if you are polite.The whole poem is giving instructions on how to please the creatures of the forest, and this explains how they will return your politeness.

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/P1JYbJvUEfGtC_vqsSZkTA

Published: August 19, 2026 13:45

Trust the wolves, but do not tell them where you are going.Gaiman's fantasy poem includes lots of creative writing, and some references too. I highlighted the part about the wolves because I think it is a reference to Little Red Riding Hood because she…

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/OZexppvUEfGi9Vc_RERZYQ

Published: August 19, 2026 13:45

Walk through the house. Take nothing. Eat nothing. However, if any creature tells you that it hungers, feed it.This line promotes selflessness and generosity, whilst still giving an air of tension in the house.

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/D2k-cpvUEfGiWRs7chfK_g

Published: August 19, 2026 13:44

Trust the wolves, but do not tell them where you are going.I think this passage means that you should give people with a bad reputation a chance, but be careful around them.

https://bafkreigwgp2bucfqaijb55ufmdot7cm4mmqamf3atjwnudpjf4uqwzg22i.ipfs.inbrowser.link/?filename=GMT20260812-140213_Recording.transcript.vtt

https://hypothes.is/a/9vstyJvTEfGE-KNQptencg

Published: August 19, 2026 13:43

CryptPad document related to this experiment https://cryptpad.fr/pad/#/2/pad/edit/uN+-lwNmfm4RdDhCwRIjBPjj/

How can LLM RL Work Despite Information-Theoretic Inefficiency

https://hypothes.is/a/icwCkJvTEfGE3BMByGHVgw

Published: August 19, 2026 13:40

can successfully solve tasks where the required change is relatively few bits away from the baseif the base model has 0% chance to succeed then every rollout will essentially be a "fail" and we don't have a useful learning setting. we want to differentiate…

https://bafkreigwgp2bucfqaijb55ufmdot7cm4mmqamf3atjwnudpjf4uqwzg22i.ipfs.inbrowser.link/?filename=GMT20260812-140213_Recording.transcript.vtt

https://hypothes.is/a/S-N6OpvTEfGq9c_mFik1qQ

Published: August 19, 2026 13:38

on my asus machine indy0 brave profile 🟡🌱indy0☯🦁@zen@brave [IndyWikiPad/?transcript-Dialogue2.0~call-2026-8-12%C2%A0@ 🟡🌱indy0☯🦁~](@zen@bravehttps://indy.peergos.me/Wiki/Pad/?t=transcript-Dialogue2.0~call-2026-8-12%C2%A0)

Poem 6: Instructions by Neil Gaiman – Dr. Bevill's English 1 Honors

https://hypothes.is/a/RQZlsJvTEfGOBTPwLnZwWA

Published: August 19, 2026 13:38

do not touch it; it will bite your fingers. Walk through the house. Take nothing. Eat nothing. However, if any creature tells you that it hungers, feed it. If it tells you that it is dirty, clean it. If it cries to you that it hurts, if you can, …

How can LLM RL Work Despite Information-Theoretic Inefficiency

https://hypothes.is/a/LflQMJvTEfGftDdbZkbWYQ

Published: August 19, 2026 13:37

next token prediction, which is essentially a massive ensemble of a huge variety of sub-tasksthese tasks are implicit and improving NTP coincidentally improves since pretraining data is some projection of the world which happens to often be concerning…

Quarterly financial report for the quarter ended June 30, 2026

https://hypothes.is/a/9saNMJvSEfGp53te2Gft-g

Published: August 19, 2026 13:36

Hi is it possible to switch the text with the budgetary authorities and expenditures at quarter end that I'll upload to the ticket

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

https://hypothes.is/a/6bmu2Ju-EfG7jTtbCuk5MA

Published: August 19, 2026 11:12

**eLife Assessment** This important study combines cryo-EM, biochemical, and cell-based assays to examine how Gβγ interacts with and potentiates PLCβ3. The authors present evidence for multiple Gβγ interaction surfaces and argue that Gβγ primarily…

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

https://hypothes.is/a/6R7b2Ju-EfGjzEd7VIw3Ag

Published: August 19, 2026 11:12

**Reviewer #3 (Public review):** Summary: PLCβ3 is activated by both Gαq and Gβγ subunits. This paper follows previous solution and cryoEM studies of the PLCβ3 / Gβγ complex to delineate the molecular details of activation using cellular BRET…

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

https://hypothes.is/a/6YZc1pu-EfGN7-P4U1eWxA

Published: August 19, 2026 11:12

**Reviewer #1 (Public review):** The manuscript by Fisher et al describes the molecular mechanism underlying how G beta gamma subunits engage with the beta 3 isoform of PLC. The paper used a combination of cryo EM, BRET assays, and biochemical assays…

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

https://hypothes.is/a/6VTX4pu-EfGejbfyyqHE1Q

Published: August 19, 2026 11:12

**Reviewer #2 (Public review):** In this manuscript, the authors dissect how Gβγ potentiates PLCβ3 signaling in cells. Using engineered crosslinking to stabilize a Gβγ-PLCβ3 complex, single particle cryo-EM, and cell-based functional assays, they…

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

https://hypothes.is/a/6ObULJu-EfGe6xfGpHgjBQ

Published: August 19, 2026 11:12

**Author response:** The following is the authors’ response to the original reviews. > **Public Reviews:** > **Reviewer #1 (Public review):** > The manuscript by Fisher et al describes the molecular mechanism underlying how G beta gamma subunits engage…

eXtensible Host Controller Interface for Universal Serial Bus (xHCI)

https://hypothes.is/a/RlNO_pu8EfGyT7vlJHRfLw

Published: August 19, 2026 10:53

The xHCI is used for all communications to devices connected through the Root Hub ports of the USB3 host controller.xhciはUSB3ホストコントローラーのルートハブを通じてデバイスを繋げるための全ての通信を使用します。

eXtensible Host Controller Interface for Universal Serial Bus (xHCI)

https://hypothes.is/a/Jb-Dupu8EfGh5IOl03ZA_g

Published: August 19, 2026 10:53

Native OS support for Device Classes allows a compliant device to provide a user with basic functionality if the vendor Device Class drivers are not available, however a vendor can define their own Class Driver to add value. Many commodity USB device…

Trail Maintenance Certification — Kalamunda Mountain Bike Collective

https://hypothes.is/a/qU8pwpu5EfGJvWu11wx_nw

Published: August 19, 2026 10:35

KMBC Trail Maintenance WorkingAn example annotation. You can leave comments by selecting text and clicking the '"' symbol. More options using the buttons on the top-right of the page.

1  Manuscript – The problem with the OME metric

https://hypothes.is/a/oQDycJu3EfGZ3PPEqZOSKg

Published: August 19, 2026 10:20

I think there was an obligation with regards to funding that research teams had to use their conversion sets. How can I rephrase?

Nerve Injury-Induced Protein 2 Is Necessary for the Lysosome Membrane Integrity and Protects Cells from Ferroptosis

https://hypothes.is/a/kG2kwJuuEfGyrm9wTT6lyA

Published: August 19, 2026 09:15

**eLife Assessment** This fundamental work uncovers an unexpected lysosomal function for NINJ2 and links it to ferroptosis and cancer biology. The evidence supporting the conclusions appears to be convincing. This work will be of general interest to…

Nerve Injury-Induced Protein 2 Is Necessary for the Lysosome Membrane Integrity and Protects Cells from Ferroptosis

https://hypothes.is/a/kDupDJuuEfGfHjN81H3ppw

Published: August 19, 2026 09:15

**Reviewer #1 (Public review):** Summary: This study reports a novel and potentially impactful role for NINJ2 in maintaining lysosomal integrity and regulating cellular susceptibility to ferroptosis. The authors demonstrate that NINJ2 localizes…

Nerve Injury-Induced Protein 2 Is Necessary for the Lysosome Membrane Integrity and Protects Cells from Ferroptosis

https://hypothes.is/a/kAOwzpuuEfGxslNinfe-TQ

Published: August 19, 2026 09:15

**Reviewer #2 (Public review):** This manuscript, "Nerve Injury-Induced Protein 2 preserves lysosomal membrane integrity to suppress ferroptosis", identifies a previously unrecognized function of NINJ2 as a regulator of lysosomal membrane integrity…

Nerve Injury-Induced Protein 2 Is Necessary for the Lysosome Membrane Integrity and Protects Cells from Ferroptosis

https://hypothes.is/a/j8_PUpuuEfGyIXfvgqyVng

Published: August 19, 2026 09:15

**Author response:** The following is the authors’ response to the original reviews. > **Public Reviews:** > **Reviewer #1 (Public review):** > Summary: > This study reports a novel and potentially impactful role for NINJ2 in maintaining lysosomal…

The Drosophila IR20a Integrates L-arginine and Salt Signals via Distinct Subunit Assemblies

https://hypothes.is/a/gWXyqJutEfGOYXOU3XY4Lg

Published: August 19, 2026 09:08

**eLife Assessment** This valuable study uses genetic, behavioural, neuronal activity and cell-based assays to show that the Drosophila ionotropic receptor IR20a contributes to the detection of arginine and low-sodium salt, and suggests that…

The Drosophila IR20a Integrates L-arginine and Salt Signals via Distinct Subunit Assemblies

https://hypothes.is/a/gTeSeJutEfGdFoO6ZHeOkg

Published: August 19, 2026 09:08

**Reviewer #1 (Public review):** Summary: The authors investigated the function of a Drosophila chemosensory receptor, IR20a, using genetics, neuronal histology, calcium imaging (in vivo and in cultured cells), and behavioral approaches. They…

The Drosophila IR20a Integrates L-arginine and Salt Signals via Distinct Subunit Assemblies

https://hypothes.is/a/gQUZLputEfG2s0NLGjEwog

Published: August 19, 2026 09:08

**Reviewer #2 (Public review):** Summary: This study identifies IR20a-expressing gustatory neurons in Drosophila as a multimodal sensory population integrating amino acid (arginine) and low-salt signals through combinatorial IR20a/IR25a/IR76b…

The Drosophila IR20a Integrates L-arginine and Salt Signals via Distinct Subunit Assemblies

https://hypothes.is/a/gJfefJutEfGjqGdVCCdyFQ

Published: August 19, 2026 09:08

**Author response:** We thank the editors and three reviewers for their careful evaluation and constructive feedback. We are pleased that our identification of IR20a as a multimodal tuning receptor required for both low-salt and arginine sensing in a…

The Drosophila IR20a Integrates L-arginine and Salt Signals via Distinct Subunit Assemblies

https://hypothes.is/a/gM3OzputEfGX32sfhU58iA

Published: August 19, 2026 09:08

**Reviewer #3 (Public review):** Summary: Drosophila, like other animals, use sophisticated taste systems with specialized chemoreceptors to identify gustatory cues in their environment. Multiple gustatory cues associated with a food source are…

A senescent-immune reserve niche model for incomplete lobular involution in the aging breast

https://hypothes.is/a/PJ2KyJutEfGk7nMYLxZ6qg

Published: August 19, 2026 09:06

**eLife Assessment** This Review delineates postmenopausal age-related lobular involution (ARLI) in the breast that remains only partially resolved. In contrast to the conventional view of persistent lobules as passive residual structures, this work…

A senescent-immune reserve niche model for incomplete lobular involution in the aging breast

https://hypothes.is/a/OnuhHJutEfGu88M-MZSq7w

Published: August 19, 2026 09:06

**Reviewer #1 (Public review):** Summary: This Perspective proposes a conceptual model in which incomplete age-related lobular involution (ARLI) in the breast reflects an actively maintained senescent-immune "reserve niche," rather than simply passive…

A senescent-immune reserve niche model for incomplete lobular involution in the aging breast

https://hypothes.is/a/NsRKJJutEfGtti813XMTNQ

Published: August 19, 2026 09:06

**Reviewer #2 (Public review):** Summary: This review constructs a novel theoretical framework to elucidate incomplete postmenopausal age-related lobular involution (ARLI) in the breast. Differing from the conventional view of persistent lobules as…

A senescent-immune reserve niche model for incomplete lobular involution in the aging breast

https://hypothes.is/a/LaQ8YJutEfGNSd_p6zOBnA

Published: August 19, 2026 09:05

**Author response:** We thank the editors and reviewers for recognizing the originality and potential value of the proposed framework. The reviews rightly ask us to distinguish three things more sharply: what is established directly in human breast…

Local Roots Within a National Political Divide: Evidence from a Split-Ballot Candidate Conjoint in Poland

https://hypothes.is/a/Ml9ZypusEfGe5nMvI5wTUQ

Published: August 19, 2026 08:58

Three limits qualify the conclusions.these findings. First, the released materials do not include the verbatim outcome screen: the technical report refers to a preferred profile, whereas the data label refers to the candidate judged more competent. The…

Local Roots Within a National Political Divide: Evidence from a Split-Ballot Candidate Conjoint in Poland

https://hypothes.is/a/3X_ZNJurEfGuBoswcUghXA

Published: August 19, 2026 08:56

Related studiesbased on election results - o ile one takie właśnie są. Przedstawiałbym experimental evidence jako kompatybilny względem registry data

Local Roots Within a National Political Divide: Evidence from a Split-Ballot Candidate Conjoint in Poland

https://hypothes.is/a/gKQ74purEfGk7Cv3fPWqjg

Published: August 19, 2026 08:53

attitude cutoffs.niejasne "attitude cutoffs" - może lepiej alternative cutoff points defining political (party) alignment

Local Roots Within a National Political Divide: Evidence from a Split-Ballot Candidate Conjoint in Poland

https://hypothes.is/a/TmTT7purEfGXBwfhDSUtSA

Published: August 19, 2026 08:52

Government alignment has larger point estimatesAligmnent effects have larger magnitude.

The Town of Vallaki

https://hypothes.is/a/eZH9XpuqEfG7TNfw5PTJtA

Published: August 19, 2026 08:46

In the center of the room, perched on a stool, is a thin young man with a premature streak of gray in his dark hair. He cradles an open leather-bound book in his arms.**PLAYER INFO:** He sees you and says did my father send you? **DM INFO:** Victor, if…

PMID_39255019-html.html

https://hypothes.is/a/nRin2JupEfGGqed6TT9RBQ

Published: August 19, 2026 08:40

BDSC 58320DOI: 10.7554/elife.93604 Resource: RRID:BDSC_58320 Curator: @maulamb SciCrunch record: RRID:BDSC_58320 What is this?

INTS6 loss of function disrupts transcriptional regulation in mild intellectual disability

https://hypothes.is/a/nJWEIJupEfGi1RPBnPcUEQ

Published: August 19, 2026 08:40

Addgene_52047DOI: 10.64898/2026.07.17.737701 Resource: RRID:Addgene_52047 Curator: @sonofthor SciCrunch record: RRID:Addgene_52047 What is this?

Mechanically induced pre-mitotic nuclear deformations promote nuclear rupture through lamin B1 depletion

https://hypothes.is/a/nO2mKJupEfG2vM95GtP8lQ

Published: August 19, 2026 08:40

Addgene_55069DOI: 10.64898/2026.07.17.739104 Resource: RRID:Addgene_55069 Curator: @sonofthor SciCrunch record: RRID:Addgene_55069 What is this?

INTS6 loss of function disrupts transcriptional regulation in mild intellectual disability

https://hypothes.is/a/nMG-5pupEfG2sZt2zo0_gQ

Published: August 19, 2026 08:40

Addgene_19780DOI: 10.64898/2026.07.17.737701 Resource: RRID:Addgene_19780 Curator: @sonofthor SciCrunch record: RRID:Addgene_19780 What is this?

Cryo-electron tomography of Nipah virus structural protein complexes in virus-like particles

https://hypothes.is/a/nG3wXpupEfGyq7cXrv5V-w

Published: August 19, 2026 08:40

SCR_022900DOI: 10.64898/2026.07.16.738223 Resource: University of California at Los Angeles California NanoSystems Institute Electron Imaging Center for Nanomachines Core Facility (RRID:SCR_022900) Curator: @sonofthor SciCrunch record: RRID:SCR_022900 …

Intermolecular disulfide bond formation promotes Hsp42 higher-order assembly and shapes client selection in yeast

https://hypothes.is/a/m_X7qJupEfGpWCtru0eX9A

Published: August 19, 2026 08:40

SCR_027015DOI: 10.64898/2026.07.13.738256 Resource: RRID:SCR_027015 Curator: @sonofthor SciCrunch record: RRID:SCR_027015 What is this?

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