@bsky.app.profile.dereklowe.bsky.social@rss-parrot.net
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Medicinal chemist / chemical biologist, author of “In the Pipeline” at http://science.org/blogs/pipeline. All opinions are mine; I don’t speak for my employer in any way.
Site URL: bsky.app/profile/dereklowe.bsky.social
Feed URL: bsky.app/profile/did:plc:yeyl36oymo6dp6rlgibtljvo/rss
Posts: 10
Followers: 1
https://bsky.app/profile/dereklowe.bsky.social/post/3mjxfexzoqc2m
Published: April 20, 2026 21:18
Like most drug discovery researchers, I’ve been watching the “peptides for everything” craze with a mixture of amusement and alarm: https://www.science.org/content/blog-post/ah-peptides-where-begin
https://bsky.app/profile/dereklowe.bsky.social/post/3mjvh2eubas2v
Published: April 20, 2026 02:42
Agree completely. This looks like a variation on good ol' staurosporine, which hits half the kinases known to man. This compound is great news, but surely not because it's some sort of selective inhibitor. [contains quote post or other embedded content]
https://bsky.app/profile/dereklowe.bsky.social/post/3mjnsgrc3gc2v
Published: April 17, 2026 01:45
Looks like the Dark-Eyed Junco birds have finally left the neighborhood here in Eastern MA. They show up in the fall from Canada; this is their Florida, the little weirdos. I've been watching every day. Tuesday they were around. Yesterday I saw only one.…
https://bsky.app/profile/dereklowe.bsky.social/post/3mjneswjqys2g
Published: April 16, 2026 21:41
The possibility of an opioid pain-relief compound with fewer side effects and lower addiction potential. Let’s hope it pans out: https://www.science.org/content/blog-post/new-opioid-agonist
https://bsky.app/profile/dereklowe.bsky.social/post/3mjnbmv4zgc2g
Published: April 16, 2026 20:44
This is the horrible secret sauce behind some of Trump’s public supporters, not to mention his enemies. If you turn against him, the death threats start. It’s no way to run a country. [contains quote post or other embedded content]
https://bsky.app/profile/dereklowe.bsky.social/post/3mjkprog3vc2g
Published: April 15, 2026 20:19
I guarantee that you have not considered this method of CNS drug delivery! https://www.science.org/content/blog-post/right-through-skull
https://bsky.app/profile/dereklowe.bsky.social/post/3mjk63abwo22g
Published: April 15, 2026 15:02
Man, I sure hope this goes according to plan! [contains quote post or other embedded content]
https://bsky.app/profile/dereklowe.bsky.social/post/3mjjudm3hj22q
Published: April 15, 2026 12:08
Evidence that you can make lipid nanoparticle delivery work much better by giving the dose along with amino acid supplements. Who knew? https://www.science.org/content/blog-post/revving-lnp-delivery
https://bsky.app/profile/dereklowe.bsky.social/post/3mjhtvjvh2s2n
Published: April 14, 2026 16:55
Improving CAR-T therapies very important work, but it can be pretty painful going: https://www.science.org/content/blog-post/latest-car-t-work
https://bsky.app/profile/dereklowe.bsky.social/post/3mjfqslo33c2z
Published: April 13, 2026 20:54
Is part of fentanyl’s high activity as an opioid agonist because it slides through cell membranes even more quickly than morphine? https://www.science.org/content/blog-post/fentanyl-s-membrane-behavior